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Causes and prognosis of adults experiencing a first seizure in adulthood: A pilot cohort study conducted in five countries in Latin America
No full textThere are limited data on first seizure (FS) among adults in low and middle-income countries. We describe findings from a prospective cohort study involving 180 adults presenting with seizures in emergency departments in five Latin American countries. Overall, 102 participants (56.7%) had acute symptomatic seizures (ASyS) while 78 (43.3%) had unprovoked seizures (UPS). Among patients with ASyS, 55 (53.9%) had structural causes, with stroke (n = 24, 23.5%), tumor (n = 10, 9.8%), and trauma (n = 3, 3%) being the most frequent. Nineteen patients (18.6%) had infectious causes, including four (4%) with meningoencephalitis, three (3%) neurocysticercosis, and two (2%) bacterial meningoencephalitis. Twenty patients (19.6%) had metabolic/toxic evidence, including four (4%) with uremic encephalopathy, two (2%) hyponatremia, and three (3%) acute alcohol intoxication. Immune dysfunction was present in seven (7%) patients and neurodegenerative in two (2%). Among participants with UPS, 45 (57.7%) had unknown etiology, 24 (30.7%) had evidence of structural disorders (remote symptomatic), four (5%) were related to infectious etiology (>7 days before the seizure), and five (6.4%) had genetic causes. During the 3- and 6-month follow-up, 29.8% and 14% of patients with UPS, respectively, experienced seizure recurrence, while 23.9% and 24.5% of patients with ASyS had seizure recurrence. Longer follow-up is necessary to assess seizure recurrence for patients with ASyS after the acute cause is resolved and to determine the 10-year risk of recurrence, which is part of the definition of epilepsy. Plain Language Summary: We monitored 180 adults who presented with their first seizure in emergency departments across five Latin American countries. Among these patients, 57% had acute symptomatic seizures, with structural causes such as stroke (23%), infection (17%), or tumor (10%) being more prevalent. Among the 43% with unprovoked seizures, 58% showed no identifiable acute cause, while 6.4% were due to genetics. Within 3 months after their initial seizure, 26.6% of individuals experienced a second seizure, with 11.9% continuing to have seizures in Months 3–6. Between Months 3 and 6, an additional 20% of patients encountered a second seizure. Research is needed to better understand the cause and prognosis of these patients to improve outcomes
Diferencias sonoras del arco barroco y el arco moderno en la ejecución de las Variaciones sobre las Folías de España de Marin Marais
No full textEl presente trabajo propone una guía de interpretación sobre Las Variaciones de las Folías
de España escrita por Martin Marais, edición de P. Bazelera, partiendo del estudio de los
diferentes tipos de arcos utilizados para la interpretación de esta pieza. Para dicho propósito
se identificarán los tipos de arcos utilizados. Otorgando especial importancia al arco barroco
de la época, el cual fue construido y utilizado en la interpretación de la pieza con el propósito
de presentar diferentes perspectivas de sonidos producidos por estos arcosThe present work proposes an interpretation guide on "The Variations of the Folías the Spain"
written by Martin Marais, edition by P. Bazelera, starting from the study of the different types
of bows used for the interpretation of this piece. For this purpose, the types of bows used will
be identified. Special importance will be given to the baroque bow of the time, which was built
and used in the interpretation of the piece with the purpose of presenting different perspectives
of sounds produced by these bows0009-0007-0215-605
Efecto del uso de probióticos sobre la salud y la calidad de leche en vacas Holstein Friesian en lactancia
No full textEl objetivo de esta investigación fue determinar el efecto de probióticos en la salud y calidad
láctea de vacas Holstein. Los tratamientos fueron: T1 control; T2 dieta basal, más 50 ml del
probiótico con bacterias L. acidophillus. y L. bulgaricus; T3 con dieta basal, y 50 ml del
probiótico K. fragilis y S. cerevisiae. Los cuales se repitieron 6 veces durante 75 días. Se
utilizó un Diseño Completamente Aleatorizado. Se midieron los glóbulos rojos, glóbulos
blancos, hemoglobina, volumen corpuscular medio y plaquetas. Se midió Colesterol,
Proteínas totales y Aspartato aminotransferasa. El recuento de glóbulos rojos fue superior
para T1 (P<0,10) con 10,15 109
/ L el día 0. PLT fue mayor en T2 presentado 375,83 109
/ L
el día 0 y mayor para T3 en el día 75 con 366,50 109
/ L (P<0,10). La hemoglobina fue alta en
T1 (P<0,10) con 103,17 109
/ L el día 45. En Calidad Láctea a 60 días, T3 fue mayor (P<0,10)
em grasa con 3,52%, ́proteína 3,13%, lactosa 4,80%, solidos no grasos 8,72%. T3 fue mayor
también a los 75 (P<0,10), en grasa 3,67%, proteína 3,22% solidos no grasos 8,88% solidos
totales 12,55% sales 0.67%. Se confirman las posibilidades del uso de biopreparados
probióticos con actividad antimicrobiana en la producción de alimento para animales de
interés zootécnico, además de sus efectos en indicadores de calidad láctea, hematológicos y
de bioquímica sanguínea en vacas lecheras en el primer tercio de lactancia; presentando
cambios en los últimos días del ensayoThe aim of this research was to determine the effect of probiotics on the health and milk quality
of Holstein cows. The treatments were as follows: T1 control; T2 basal diet plus 50 ml of
probiotic containing L. acidophilus and L. bulgaricus; T3 basal diet plus 50 ml of probiotic
containing K. fragilis and S. cerevisiae. These treatments were repeated 6 times over 75 days.
A Completely Randomized Design was used. Red blood cells, white blood cells, hemoglobin,
mean corpuscular volume, and platelets were measured. Cholesterol, total proteins, and
aspartate aminotransferase were also measured. The red blood cell count was higher for T1
(P<0.10) at day 0 with 10.15 × 10^9/L. Platelets were higher in T2 at day 0 with 375.83 ×
10^9/L and higher for T3 at day 75 with 366.50 × 10^9/L (P<0.10). Hemoglobin was high in T1
(P<0.10) at day 45 with 103.17 × 10^9/L. At 60 days, T3 showed higher milk quality (P<0.10)
in fat with 3.52%, protein 3.13%, lactose 4.80%, and non-fat solids 8.72%. T3 also showed
higher values at 75 days (P<0.10), in fat 3.67%, protein 3.22%, non-fat solids 8.88%, total
solids 12.55%, and salts 0.67%. The potential use of probiotic biopreparations with
antimicrobial activity in animal feed production of zootechnical interest is confirmed, in addition
to their effects on milk quality, hematological, and blood biochemical indicators in dairy cows
in the first third of lactation; showing changes in the final days of the trial0009-0000-2082-713
Effect of resveratrol supplementation in conventional slow and ultra-rapid freezing media on the quality and fertility of bull sperm
No full textThe study investigated the impact of resveratrol (RES) on bull sperm cryopreservation employing conventional slow (CS) and ultra-rapid (UR) freezing methods on sperm quality and in vitro fertility. Twenty-four ejaculates from four bulls were divided into four groups based on the cryopreservation method and RES addition: CS-RES (n = 80), CS-Co (n = 80), UR-RES (n = 24), and UR-Co (n = 24). The CS freezing involved exposing sperm straws with 5% glycerol to liquid nitrogen (LN2) vapors, while UR freezing submerged sperm drops with 100 mM sucrose directly into LN2. Overall, sperm kinematic parameters and integrity of plasma and acrosome membranes significantly decreased (P < 0.001) after cryopreservation. Post-thaw values of motilities (total [TM] and progressive [PSM]), velocities (curvilinear and straight-line), beat cross frequency (BCF), and sperm with intact plasma membrane/intact acrosome (PI-/PNA-) were higher (P < 0.05) with CS-RES and CS-Co treatments compared to UR-RES and UR-Co treatments. CS-RES treatment resulted in greater percentages (P < 0.05) of TM, PSM, PI-/PNA-, and fertility (blastocyst rate) than their control, CS-Co; while UR-RES showed higher BCF values (P < 0.05) than its control, UR-Co. Additionally, UR-RES treatment exhibited lower oxidative stress percentages than UR-Co (P < 0.05). This study presents the following conclusions: (1) the CS freezing resulted in better cryosurvival of bull sperm than UR freezing; (2) the RES supplementation to CS freezing medium improved sperm motility, membrane integrity, and fertility; and (3) despite low cryosurvival sperm and fertility, the RES addition to ultra-rapid freezing medium reduced oxidative stress
The moon cycle influences reproductive and productive traits in guinea pigs (Cavia porcellus) from a tropical Andean area
No full textThere is currently innumerable evidence showing that the lunar cycle affects various reproductive aspects in farm animals. However, there is very little information on the effect of the lunar cycle on productive traits in these species. A retrospective study was conducted (2015–2018) to evaluate the influence of the lunar cycle on some reproductive and productive traits in a guinea pig (Cavia porcellus) production system in the southern Andean region of Ecuador. A total of 7352 productive and reproductive records of guinea pig females housed in 3 m2 cages with a breeding male were analyzed. The following variables were considered: offspring sex ratio, litter size per cage, number of weaned guinea pigs, mortality, individual and litter weaning weight of guinea pigs, and delivery frequency. The lunar cycle was split into eight periods of ~3.7-d length each. Data were analyzed by logistic regression and general linear model, and means were compared by the least mean squares method of the SAS. The offspring sex ratio was not correlated to the lunar cycle. The lunar cycle at mating and parturition influenced the litter size per cage, number of weaned, and mortality of guinea pigs. The individual and litter-weaning weights were influenced by the lunar cycle at parturition. The frequency of deliveries was greater around the new and full moon than in the remaining periods of the lunar cycle. In conclusion, the lunar cycle influenced several productive and reproductive traits in guinea pigs, such as litter size, mortality, number of pups weaned, and individual and litter weaning weights. This valuable information may have practical applications in management of guinea pig production systems
Visibilización en sistema de la tribu urbana Hip-Hop, para su comprensión sociocultural integrada en una propuesta mural contemporánea
No full textEl movimiento Hip-Hop ha evolucionado a lo largo de las décadas en formas que resultan
extremadamente diversas, pues abarca una gran variedad de elementos como la música, la
danza, el graffiti y la moda. En múltiples ocasiones se lo ha asociado con estereotipos
negativos que establecen una comprensión errónea y muy limitada de lo que realmente
implica; ya que no todas las personas tienen acceso a una información completa sobre el Hip Hop. Ante esta problemática, se propuso plasmar en un mural a la Cultura Hip-Hop con base
en sus cuatro fundamentos: breakdancing, graffiti, rapping y turntablism. Dicho de otro modo,
se pretendió difundir este arte mediante una propuesta visual contemporánea a fin de entablar
una comprensión sociocultural integradora. A tal efecto, se elaboró un mural de estilo
caricatura con pintura de exteriores que consistió en la representación de personajes
femeninos y masculinos, con elementos representativos de varias tribus urbanas que
convergen en el Hip-Hop. Dichos elementos acentuaron la expresividad de los personajes
para dejar un manifiesto visual de, qué es y cómo se conforma el hip-hop como movimiento
artístico-cultural. Todo esto para contribuir a una asimilación e impacto positivo de la cultura.
Esta experiencia estética propició el reconocimiento e identificación iconográfica de
elementos seleccionados que aluden a la Hip-Hop, con énfasis en la mujer artista, frente a
una tradición en que frecuentemente se le omite; todo ello, a través de la belleza, el diálogo
con la apropiación de espacios comunitarios.The Hip-Hop movement has evolved over the decades in ways that are extremely diverse,
encompassing a wide variety of elements such as music, dance, graffiti and fashion. On
multiple occasions it has been associated with negative stereotypes that established an
erroneous and very limited understanding of what it really implies; since not all people have
access to complete information about Hip-Hop. Faced with this problem, it was proposed to
capture Hip-Hop Culture in a mural based on its four foundations: breakdance, graffiti, rap and
turntablism. In other words, the aim was to disseminate this art through a contemporary visual
proposal in order to establish an integrative sociocultural understanding. To this end, a
caricature-style mural was created with outdoor painting that consisted of the representation
of female and male characters, with representative elements of various urban tribes that
converge in Hip-Hop. These elements accentuated the expressiveness of the characters to
leave a visual manifesto of what hip-hop is and how it is shaped as an artistic-cultural
movement. All this to contribute to the assimilation and positive impact of culture. This
aesthetic experience led to the recognition and iconographic identification of selected
elements that allude to Hip-Hop, with emphasis on the female artist, in the face of a tradition
in which she is frequently omitted; all of this, through beauty, dialogue with the appropriation
of community spaces.0000-0002-3423-653
Design of a mass valuation system for urban land based on the land rent theory. Application to the case of Cuenca, Ecuador
No full textLas municipalidades, frente a la obligatoriedad de generar avalúos prediales, predominantemente han empleado el método de comparación, caracterizado por someterse a las distorsiones del mercado de suelo, excluyendo la consideración explícita de factores que lo valorizan. En este artículo se expone un método de valuación masiva del suelo urbano basado en la generación de rentas de suelo que valorizan la propiedad y que, en su forma capitalizada, se expresan en su precio. A través de la aplicación en la ciudad de Cuenca, se establece un conjunto de procedimientos para la determinación del precio unitario base, identificando para ello el capital incorporado al suelo en infraestructuras y equipamientos, y cuantificando las rentas primarias y secundarias más relevantes a partir de las expresiones de la estructura espacial de los usos de suelo vinculadas a su generación. Los resultados obtenidos demuestran que la teoría de la renta de la tierra es aplicable a la valuación masiva del suelo urbano con fines catastrales, obteniendo un significativo grado de comprensión sobre la conformación de los precios del suelo en la ciudad asociados a sus dinámicas.The municipalities, faced with the obliga-tion to generate property appraisals, have predom-inantly used the comparison method, characterized by submitting to the distortions of the land market, excluding the explicit consideration of factors that value it. This article presents a method of valuing urban land massively, based on the generation of land rents that value the property and that in its capitalized form are expressed in its price. Through the application in the city of Cuenca, a set of pro-cedures is established for the determination of the base unit price, identifying for this the capital incor-porated into the land in infrastructures and equip-ment, and quantifying the most relevant primary and secondary rents from the expressions of the spatial structure of land uses linked to their gener-ation. The results obtained show that the theory of land rent is applicable to the massive valuation of urban land for cadastral purposes, obtaining a sig-nificant degree of understanding of the conforma-tion of land prices in the city associated with their dynamic
Manifestaciones Musculoesqueléticas Post-Covid19 en la población de la parroquia Ricaurte. Periodo marzo 2020 - septiembre 2023. Cuenca - Ecuador
No full textAntecedentes: las manifestaciones post-Covid19 son diversas y afectan múltiples sistemas
entre ellos el musculoesquelético, provocando síntomas como fatiga, mialgias y artralgias que
pueden prolongarse hasta 60 días posteriores a la infección, impactando negativamente la
calidad de vida de los pacientes. Estas manifestaciones forman parte del llamado “Síndrome
de Covid Prolongado”. Objetivo: determinar las principales manifestaciones
musculoesqueléticas post-Covid19 en la población de la parroquia Ricaurte, periodo marzo
2020 - septiembre 2023. Cuenca - Ecuador. Métodos: se trata de un estudio descriptivo, que
toma como universo a adultos entre 18-65 años residentes en Ricaurte, la muestra consta de
164 participantes seleccionados a conveniencia. La información se obtuvo mediante un
cuestionario, los datos obtenidos fueron procesados aplicando el programa SPSS versión
25.0, utilizando estadígrafos de frecuencias y porcentajes para su evaluación y análisis.
Resultados: las manifestaciones musculoesqueléticas se presentaron en 89,6% de los
participantes, en su mayoría adultos entre 30 a 60 años (53%), principalmente hombres
(46,3%), con educación secundaria (53%), la mayor parte no presentaban comorbilidades
(56,7%), no se encontraban vacunados (66,5%), y recibieron atención ambulatoria (84,1%).
Las principales manifestaciones encontradas fueron dolor muscular (74,1%), dolor articular
(46,9%), y debilidad muscular (46,3%), la intensidad del dolor fue moderada (51,8%), y se
localizó en cuello (58,8%), rodillas (31,3%) y espalda alta (51,1%), la duración de la
sintomatología fue de 2 a 4 semanas (54,4%). Conclusiones: la presencia de manifestaciones
musculoesqueléticas post-Covid19 fue alta, siendo las mialgias de intensidad moderada el
síntoma más prevalente, con una prolongación de hasta 4 semanas post-infección.Background: the post-Covid19 manifestations can be varied and affect multiple systems
including the musculoskeletal, causing symptoms such as fatigue, myalgias and arthralgias
which can extend up to 60 days after the infection, causing a negative impact to the quality of
life of patients. These symptoms are part of the syndrome known as “Long Covid”. Objective:
to determine the main post-Covid19 musculoskeletal manifestations in the population of
Ricaurte, March 2020 - September 2023. Cuenca - Ecuador. Methods: a descriptive study,
which covers all adults between 18-65 years of age residing in Ricaurte, the sample consists
of 164 participants selected by convenience. The information was obtained through a
questionnaire and the data was processed using SPSS statistics software version 25.0,
applying frequency statistics for its evaluation and analysis. Results: musculoskeletal
manifestations occurred in 89.6% of participants, who were mostly adults between 30 and 60
years old (53%), the majority were men (46.3%), with secondary education (53%), the most
part did not have comorbidities (56.7%), hadn’t been vaccinated (66.5%), and received only
ambulatory care (84.1%). The main manifestations included muscular pain (74.1%), joint pain
(46.9%), and muscle weakness (46.3%), the intensity of the pain was moderate (51.8%), and
was located in neck (58.8%), knees (31.3%) and upper back (51.1%), the duration of
symptoms was 2 to 4 weeks (54.4%). Conclusions: the presence of post-Covid19
musculoskeletal manifestations was high, with moderate muscle pain being the most prevalent
symptom, which lasted up to 4 weeks post-infection.0000-0002-6466-393
Propuesta gastronómica para la elaboración de macarons con base en: harina de chulpi (Zea mays sacchara), semillas de sambo (Cucurbita ficifolia) y semillas de zapallo (Cucurbita máxima) con rellenos de dulces y bebidas tradicionales del Azuay
No full textEl macaron es un representante de la repostería fina francesa, un bocadito muy apetecido
por diferentes países del mundo, por este motivo el siguiente trabajo de titulación busca,
mediante el uso de harinas de: chulpi (tostado), semillas de sambo y zapallo, la innovación
de los tradicionales macarons con rellenos de dulces y bebidas tradicionales del Azuay. Se
investigará las principales características organolépticas de cada una de las semillas, sus
beneficios para la salud, sus propiedades organolépticas, vitaminas, minerales y el consumo
de macarons en la ciudad de Cuenca, también su nivel de aceptación en el público mediante
una encuesta realizada en la facultad de ciencias de la hospitalidad. Se elaboraron fichas técnicas tanto de los macarons como de los rellenos y tomando en cuentas las características de cada dulce o bebida tradicional del Azuay se asignó un diferente tipo relleno para cada tipo de macaron. Se realizó pruebas error; la primera consistió en agregar un porcentaje de la harina de almendras en la elaboración del macaron, la segunda, es en donde se utilizó las harinas de chulpi, pepa de sambo y zapallo al 100% en la elaboración del macaron, hemos analizado y
detallado cada resultado de manera escrita y visual para que se pueda comprender el proceso
que ha tenido cada tipo de macaron. Finalmente, al culminar el presente trabajo presentamos recetas estándar de cada tipo de macaron con su respectivo relleno de bebidas y dulces tradicionales del Azuay.
Palabras claves: macarons, semillas, chulpi, sambo, zapalloThe macaron is a representative of French fine pastry, a snack highly desired by different
countries of the world, for this reason the following title work seeks, through the use of flours
of: toasted chulpi, sambo seeds and pumpkin, the innovation of traditional macarons with
fillings of sweets and traditional drinks of Azuay. The main organoleptic characteristics of each
of the seeds will be investigated, their health benefits, organoleptic properties, vitamins,
minerals, the consumption of macarons in the city of Cuenca, their level of acceptance in the
public through a survey carried out in the Faculty of Hospitality Sciences. Technical sheets
were prepared for both the macarons and the fillings and, taking into account the
characteristics of each traditional sweet or drink of Azuay, a different type of filling was
assigned for each type of macaron. Trial and error was performed; The first consisted of
adding a percentage of the almond flour in the preparation of the macaron, the second is
where the chulpi flour, sambo seed and 100% pumpkin were used in the preparation of the
macaron, we have analyzed and detailed each result in a written and visual way so that the
process that each type of macaron has had can be understood. Finally, at the end of this work,
we present standard recipes for each type of macaron with their respective filling of traditional
drinks and sweets from Azuay.
Author Keywords: macarons, seeds, chulpi, sambo, pumpkin, macaronage0000-0003-2080-047
Propuesta didáctica: Uso del GeoGebra para la Enseñanza de Oscilaciones Reales
No full textEn el presente trabajo de titulación se abordó el tema Uso del GeoGebra para la enseñanza de Oscilaciones Reales, ya que existen escasas investigaciones donde el uso del software aporte a la comprensión de los contenidos dados en la unidad de Oscilaciones Reales, lo que conlleva a que la enseñanza se vea afectada en el proceso de consolidación de los contenidos. Actualmente se desarrolla un aprendizaje mecánico donde el estudiante memoriza el concepto, sus ecuaciones, pero sin tomar en cuenta la representación gráfica y sus características. Se ha elaborado una propuesta didáctica que fomenta una enseñanza constructivista la cual cuenta con actividades que acompañadas con el uso del software GeoGebra, tiene el propósito de complementar el proceso de enseñanza. Se planteó una metodología con un enfoque cualitativo, mediante la técnica de la entrevista y la recolección de la información se la hizo por medio de un cuestionario. Con los resultados de la
investigación se pudo identificar la problemática que existe en la enseñanza de Oscilaciones Reales. Finalmente, se detalla la propuesta didáctica que inicia con una apertura de conocimientos con el fin de despertar el interés y motivación en el tema, actividades de desarrollo y consolidación de conocimientos que con el apoyo del software GeoGebra facilitan el proceso de enseñanza, permitiendo realizar representaciones gráficas, desarrollar un
aprendizaje dinámico, entretenido y significativo.In this degree work, the topic Use of GeoGebra for teaching Real Oscillations was addressed, since there is little research where the use of the software contributes to the understanding of the contents given in the Real Oscillations unit, which leads to Teaching is affected in the process of consolidating content. Currently, mechanical learning is developed where the student memorizes the concept, its equations but without taking into account the graphic representation and its characteristics. A didactic proposal has been developed that promotes constructivist teaching which has activities that, accompanied by the use of GeoGebra software, have the purpose of complementing the teaching process. A methodology was proposed with a qualitative approach, using the interview technique and the information was collected through a questionnaire. With the results of the research, it was possible to identify the problems that exist in the teaching of Real Oscillations. Finally, the didactic proposal is
detailed, which begins with an opening of knowledge in order to awaken interest and motivation in the topic, development activities and consolidation of knowledge that, with the support of the GeoGebra software, facilitate the teaching process, allowing representations to be made. graphics, develop dynamic, entertaining and meaningful learning.0000-0002-2644-134