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Effect of different load during eccentric training with blood flow restriction on muscle size, strength, and performance: A randomized controlled trial✰
Background/Objective: studies on eccentric training with blood flow restriction (BFR) still has gaps, especially in strength and muscle hypertrophy. Therefore, this study aimed to analyze and compare the effects of six weeks of eccentric training of knee extensors at different load associated or not with BFR on strength, hypertrophy, and performance of knee extensors. Methods: 61 men, healthy and untrained, performed six weeks of quadriceps muscle eccentric training in isokinetic dynamometer were randomized into four groups: high-load eccentric training with BFR (HLET-BFR), low-load eccentric training with BFR (LLET-BFR), high-load eccentric training (HLET) and low-load eccentric training (LLET). The strength, muscle structure and performance outcomes were evaluated at baseline, after 3 and 6 weeks of training. Results: for eccentric peak torque in the first three weeks, HLET was superior to LLET, but similar to LLET-BFR. In the final three weeks, superiority was observed in relation to LLET-BFR; however, there was no difference in relation to HIET-BFR. For the outcomes isometric and concentric peak torque, muscle structure and performance, there were no differences between groups. Conclusion: eccentric training led to strengthening of knee extensors and improved performance, but without altering the muscle structure. LLET-BFR promoted gains similar to HLET in the first three weeks of training.Postgraduate Program in Movement Sciences Universidade Estadual Paulista (FCT/UNESP), SPPostgraduate Program in Physiotherapy Universidade Estadual Paulista (FCT/UNESP), SPGraduate in Physiotherapy Universidade Estadual Paulista (FCT/UNESP), SPDepartment of Physiotherapy Universidade Estadual Paulista (FCT/UNESP), SPPostgraduate Program in Movement Sciences Universidade Estadual Paulista (FCT/UNESP), SPPostgraduate Program in Physiotherapy Universidade Estadual Paulista (FCT/UNESP), SPGraduate in Physiotherapy Universidade Estadual Paulista (FCT/UNESP), SPDepartment of Physiotherapy Universidade Estadual Paulista (FCT/UNESP), S
Effects of deforestation on multitaxa community similarity in the Brazilian Atlantic Forest
Habitat loss can lead to biotic homogenization (decrease in β diversity) or differentiation (increase in β diversity) of biological communities. However, it is unclear which of these ecological processes predominates in human-modified landscapes. We used data on vertebrates, invertebrates, and plants to quantify β diversity based on species occurrence and abundance among communities in 1367 landscapes with varying amounts of habitat (60% of forest cover) throughout the Brazilian Atlantic Forest. Decreases in habitat amount below 30% led to increased compositional similarity of vertebrate and invertebrate communities, which may indicate a process of biotic homogenization throughout the Brazilian Atlantic Forest. No pattern was detected in plant communities. We found that habitat loss was associated with a deterministic increase in faunal community similarity, which is consistent with a selected subset of species being capable of thriving in human-modified landscapes. The lack of pattern found in plants was consistent with known variation between taxa in community responses to habitat amount. Brazilian legislation requiring the preservation of 20% of Atlantic Forest native vegetation may be insufficient to prevent the biotic homogenization of faunal communities. Our results highlight the importance of preserving large amounts of habitat, providing source areas for the recolonization of deforested landscapes, and avoiding large-scale impacts of homogenization of the Brazilian Atlantic Forest.Natural Environment Research CouncilCentro Nacional de Conservação da Flora Jardim Botânico do Rio de JaneiroPrograma de Pós-Graduação em Ecologia Universidade Federal do Rio de JaneiroMombakInstitute for Capacity Exchange in Environmental DecisionsDepartamento de Ecologia Universidade do Estado do Rio de JaneiroDepartamento de Ecologia Universidade Federal do Mato Grosso do SulInstituto de Biociências Universidade de São PauloDepartment of Life Science Imperial College London - Silwood Park CampusDepartamento de Ecologia Universidade Federal do Rio Grande do NorteDepartamento de Ciências Florestais Universidade de São Paulo - Escola Superior de Agricultura Luiz de QueirozInstituto de Biociências Departamento de Ecologia Universidade de São PauloSenckenberg Biodiversität und Klima Forschungszentrum (BiK-F)Departamento de Biologia e Zootecnia Universidade Estadual PaulistaCampus Mata Norte Universidade de PernambucoInstituto de Biologia Universidade Federal da BahiaCentre for Ecology Evolution and Conservation School of Environmental Sciences University of East Anglia - Norwich Research ParkCentro Nacional de Monitoramento e Alertas de Desastres NaturaisSecretaria do Meio Ambiente do Estado da Bahia Instituto do Meio Ambiente e Recursos HídricosLaboratório de Ecologia Aplicada à Conservação Departamento de Ciências Biológicas Universidade Estadual de Santa CruzDepartamento de Botânica Universidade Federal do ParanáDepartamento de Ecologia Universidade de BrasíliaInstituto de Ciências da Natureza Universidade Federal de AlfenasCentro de Conservação e Manejo de Fauna da CaatingaSuperintendência de Estudos Econômicos e Sociais da BahiaDepartamento de Ciências Biológicas Universidade Regional do CaririDepartamento de Botânica Centro de Biociências Universidade Federal de PernambucoMuseu Paraense Emílio Goeldi Coordenação de Ciências da Terra e EcologiaCentro de Formação em Ciências Agroflorestais Universidade Federal do Sul da BahiaDepartamento de Ecologia e Conservação Universidade Federal de LavrasDepartamento de Ciências Biológicas Universidade Estadual do Sudoeste da BahiaDepartamento de Ecologia e Zoologia Universidade Federal de Santa CatarinaPrograma de Pós-Graduação em Ecologia Universidade Federal de SergipePrograma de Pós-graduação em Ecologia e Evolução Universidade Estadual de Feira de SantanaDepartamento de Botânica Universidade Federal de ViçosaDepartamento de Ciências Ambientais Instituto de Ciências Ambientais Químicas e Farmacêuticas Universidade Federal de São PauloDepartamento de Biologia e Zootecnia Universidade Estadual PaulistaNatural Environment Research Council: NE/K016393/
Euclid preparation: LVII. Observational expectations for redshift z < 7 active galactic nuclei in the Euclid Wide and Deep surveys
We forecast the expected population of active galactic nuclei (AGN) observable in the Euclid Wide Survey (EWS) and Euclid Deep Survey (EDS). Starting from an X-ray luminosity function (XLF), we generated volume-limited samples of the AGN expected in the Euclid survey footprints. Each AGN was assigned a spectral energy distribution (SED) appropriate for its X-ray luminosity and redshift, with perturbations sampled from empirical distributions. The photometric detectability of each AGN was assessed via mock observations of the assigned SED. We estimate 40 million AGN will be detectable in at least one Euclid band in the EWS and 0.24 million in the EDS, corresponding to surface densities of 2.8 × 103 deg-2 and 4.7 × 103 deg-2. The relative uncertainty on our expectation for Euclid detectable AGN is 6.7% for the EWS and 12.5% for the EDS, driven by the uncertainty of the XLF. Employing Euclid-only colour selection criteria on our simulated data we select a sample of 4.8 × 106 (331 deg-2 ) AGN in the EWS and 1.7 × 104 (346 deg-2 ) in the EDS, amounting to 10% and 8% of the AGN detectable in the EWS and EDS. Including ancillary Rubin/LSST bands improves the completeness and purity of AGN selection. These data roughly double the total number of selected AGN to comprise 21% and 15% of the Euclid detectable AGN in the EWS and EDS. The total expected sample of colour-selected AGN contains 6.0 × 106 (74%) unobscured AGN and 2.1 × 106 (26%) obscured AGN, covering 0.02 ≤ z ≲ 5.2 and 43 ≤ log10(Lbol/erg s-1 ) ≤ 47. With these simple colour cuts expected surface densities are already comparable to the yield of modern X-ray and mid-infrared surveys of similar area. The EWS sample is most comparable to the WISE C75 AGN selection and the EDS sample is most similar to the yield of the collated Spitzer cryogenic surveys when considering Euclid bands alone, or the XXL-3XLSS survey AGN sample when also considering selection with ancillary optical bands. We project that 15% (7.6%) of the total Euclid detectable population in the EWS (EDS) will exhibit X-ray fluxes that could be detected in the XMM-COSMOS survey, showing that the vast majority of Euclid-detected AGN would not be detectable in modern medium-depth X-ray surveys.Agenzia Spaziale ItalianaFundação para a Ciência e a TecnologiaMagyar Tudományos AkadémiaMinisterio de Ciencia, Innovación y UniversidadesNational Aeronautics and Space AdministrationSchool of Physics HH Wills Physics Laboratory University of Bristol, Tyndall AvenueINAF Istituto di Radioastronomia, Via Piero Gobetti 101Dipartimento di Fisica e Astronomia 'G. Galilei' Università di Padova, Via Marzolo 8Department of Physics Centre for Extragalactic Astronomy Durham University, South RoadMax-Planck-Institut für Astronomie, Königstuhl 17INAF Osservatorio di Astrofisica e Scienza dello Spazio di Bologna, Via Piero Gobetti 93/3Department of Physics and Astronomy University of SouthamptonJet Propulsion Laboratory California Institute of Technology, 4800 Oak Grove DriveINAF Osservatorio Astrofisico di Arcetri, Largo E. Fermi 5Dipartimento di Fisica e Astronomia Università di Firenze, Via G. Sansone 1, Sesto FiorentinoINAF Istituto di Astrofisica e Planetologia Spaziali, via del Fosso del Cavaliere, 100INAF Osservatorio Astronomico di Capodimonte, Via Moiariello 16Department of Mathematics and Physics Roma Tre University, Via della Vasca Navale 84INAF Osservatorio Astronomico di Roma, Via Frascati 33Max Planck Institute for Extraterrestrial Physics, Giessenbachstr. 1Jodrell Bank Centre for Astrophysics Department of Physics and Astronomy University of Manchester, Oxford RoadSchool of Mathematics and Physics University of Surrey SurreyINAF Osservatorio Astronomico di Brera, Via Brera 28Dipartimento di Fisica e Astronomia Università di Bologna, Via Gobetti 93/2INFN Sezione di Bologna, Viale Berti Pichat 6/2Universitäts-Sternwarte München Fakultät für Physik Ludwig-Maximilians-Universität München, Scheinerstrasse 1INAF Osservatorio Astrofisico di Torino, Via Osservatorio 20, (TO)Dipartimento di Fisica Università di Genova, Via Dodecaneso 33INFN Sezione di Genova, Via Dodecaneso 33Department of Physics 'E. Pancini' University Federico II, Via Cinthia 6INFN Section of Naples, Via Cinthia 6Instituto de Astrofísica e Ciências do Espaço Universidade do Porto CAUP, Rua das EstrelasDipartimento di Fisica Università degli Studi di Torino, Via P. Giuria 1INFN Sezione di Torino, Via P. Giuria 1INAF IASF Milano, Via Alfonso Corti 12Centro de Investigaciones Energéticas Medioambientales y Tecnológicas (CIEMAT), Avenida Complutense 40Port d'Informació Científica, Campus UAB, C. Albareda s/n, BellaterraInstitute for Theoretical Particle Physics and Cosmology (TTK) RWTH Aachen UniversityDipartimento di Fisica e Astronomia 'Augusto Righi' Alma Mater Studiorum Università di Bologna, Viale Berti Pichat 6/2Institute for Astronomy University of Edinburgh Royal Observatory, Blackford HillEuropean Space Agency ESRIN, Largo Galileo Galilei 1, FrascatiESAC ESA, Camino Bajo del Castillo, s/n., Urb. Villafranca del Castillo, Villanueva de la CañadaUniversité Claude Bernard Lyon 1 CNRS IN2P3 IP2I Lyon UMR 5822Institute of Physics Laboratory of Astrophysics Ecole Polytechnique Fédérale de Lausanne (EPFL) Observatoire de SauvernyUCB Lyon 1 CNRS IN2P3 IUF IP2I Lyon, 4 rue Enrico FermiMullard Space Science Laboratory University College London, Holmbury St Mary, DorkingDepartamento de Física Faculdade de Ciências Universidade de Lisboa, Edifício C8, Campo GrandeInstituto de Astrofísica e Ciências do Espaço Faculdade de Ciências Universidade de Lisboa, Campo GrandeDepartment of Astronomy University of Geneva, ch. d'Ecogia 16INFN Padova, Via Marzolo 8Université Paris-Saclay Université Paris Cité CEA CNRS AIMINAF Osservatorio Astronomico di Trieste, Via G. B. Tiepolo 11Istituto Nazionale di Fisica Nucleare Sezione di Bologna, Via Irnerio 46INAF Osservatorio Astronomico di Padova, Via dell'Osservatorio 5Dipartimento di Fisica 'Aldo Pontremoli' Università degli Studi di Milano, Via Celoria 16Institute of Theoretical Astrophysics University of Oslo, P.O. Box 1029 BlindernLeiden Observatory Leiden University, Einsteinweg 55Higgs Centre for Theoretical Physics School of Physics and Astronomy The University of EdinburghDepartment of Physics Lancaster UniversityFelix Hormuth Engineering, Goethestr. 17Technical University of Denmark, Elektrovej 327Cosmic Dawn Center (DAWN)Institut d'Astrophysique de Paris UMR 7095 CNRS Sorbonne Université, 98 bis boulevard AragoDepartment of Physics Helsinki Institute of Physics University of Helsinki, Gustaf Hällströmin katu 2Aix-Marseille Université CNRS IN2P3 CPPMUniversité de Genève Département de Physique Théorique Centre for Astroparticle Physics, 24 quai Ernest-Ansermet, 4Department of Physics University of Helsinki, P.O. Box 64Helsinki Institute of Physics University of Helsinki, Gustaf Hällströmin katu 2European Space Agency ESTEC, Keplerlaan 1NOVA Optical Infrared Instrumentation Group ASTRON, Oude Hoogeveensedijk 4INFN Sezione di Milano, Via Celoria 16Universität Bonn Argelander-Institut für Astronomie, Auf dem Hügel 71Aix-Marseille Université CNRS CNES LAMDipartimento di Fisica e Astronomia 'Augusto Righi' Alma Mater Studiorum Università di Bologna, via Piero Gobetti 93/2Université Paris Cité CNRS Astroparticule et CosmologieUniversity of Applied Sciences and Arts of Northwestern Switzerland School of EngineeringInstitut d'Astrophysique de Paris, 98bis Boulevard AragoIFPU Institute for Fundamental Physics of the Universe, Via Beirut 2School of Mathematics Statistics and Physics Newcastle University, Herschel BuildingDepartment of Physics Institute for Computational Cosmology Durham University, South RoadInstitut de Física d'Altes Energies (IFAE) The Barcelona Institute of Science and Technology, Campus UAB, BellaterraDepartment of Physics and Astronomy University of Aarhus, Ny Munkegade 120Waterloo Centre for Astrophysics University of WaterlooDepartment of Physics and Astronomy University of WaterlooPerimeter Institute for Theoretical PhysicsSpace Science Data Center Italian Space Agency, Via del Politecnico sncCentre National d'Etudes Spatiales - Centre spatial de Toulouse, 18 avenue Edouard Belin, Cedex 9Institute of Space Science, Str. Atomistilor, nr. 409 MǎgureleInstituto de Astrofísica de Canarias, Calle Vía Láctea s/n, TenerifeDepartamento de Astrofísica Universidad de La Laguna, TenerifeDepartamento de Física FCFM Universidad de Chile, Blanco EncaladaINFN Sezione di Roma Dipartimento di Fisica, Piazzale Aldo Moro, 2, Edificio G. MarconiUniversität Innsbruck Institut für Astro- und Teilchenphysik, Technikerstr. 25/8Institut d'Estudis Espacials de Catalunya (IEEC), Edifici RDIT, Campus UPC, CastelldefelsInstitute of Space Sciences (ICE CSIC), Campus UAB, Carrer de Can Magrans, s/nSatlantis, University Science Park, Sede BldInfrared Processing and Analysis Center California Institute of TechnologyInstituto de Astrofísica e Ciências do Espaço Faculdade de Ciências Universidade de Lisboa, Tapada da AjudaUniversidad Politécnica de Cartagena Departamento de Electrónica y Tecnología de Computadoras, Plaza del Hospital 1Institut de Recherche en Astrophysique et Planétologie (IRAP) Université de Toulouse CNRS UPS CNES, 14 Av. Edouard BelinINFN Bologna, Via Irnerio 46Institut für Theoretische Physik University of Heidelberg, Philosophenweg 16Université St Joseph Faculty of SciencesJunia EPA department, 41 Bd VaubanSISSA International School for Advanced Studies, Via Bonomea 265, TSINFN Sezione di Trieste, Via Valerio 2, TSICSC Centro Nazionale di Ricerca in High Performance Computing Big Data e Quantum Computing, Via Magnanelli 2Instituto de Física Teórica UAM-CSIC, Campus de CantoblancoCERCA ISO Department of Physics Case Western Reserve University, 10900 Euclid AvenueLaboratoire Univers et Théorie Observatoire de Paris Université PSL Université Paris Cité CNRSDipartimento di Fisica e Scienze della Terra Università degli Studi di Ferrara, Via Giuseppe Saragat 1Istituto Nazionale di Fisica Nucleare Sezione di Ferrara, Via Giuseppe Saragat 1Université de Strasbourg CNRS Observatoire Astronomique de Strasbourg UMR 7550Kavli Institute for the Physics and Mathematics of the Universe (WPI) University of Tokyo, ChibaDipartimento di Fisica - Sezione di Astronomia Università di Trieste, Via Tiepolo 11Minnesota Institute for Astrophysics University of Minnesota, 116 Church St SEInstitute Lorentz Leiden University, Niels Bohrweg 2Université Côte d'Azur Observatoire de la Côte d'Azur CNRS Laboratoire Lagrange, Bd de l'Observatoire, CS 34229, cedex 4Institute for Astronomy University of Hawaii, 2680 Woodlawn DriveDepartment of Physics & Astronomy University of California IrvineDepartment of Astronomy & Physics Institute for Computational Astrophysics Saint Mary's University, 923 Robie StreetDepartamento Física Aplicada Universidad Politécnica de Cartagena, Campus Muralla del Mar, MurciaUniversité Paris-Saclay CNRS Institut d'Astrophysique SpatialeDepartment of Physics Oxford University, Keble RoadCEA Saclay DFR IRFU Service d'Astrophysique, Bat. 709Institute of Cosmology and Gravitation University of PortsmouthDepartment of Computer Science Aalto University, PO Box 15400Ruhr University Bochum Faculty of Physics and Astronomy Astronomical Institute (AIRUB) German Centre for Cosmological Lensing (GCCL)DARK Niels Bohr Institute University of Copenhagen, Jagtvej 155Department of Physics and Astronomy University of Turku, Vesilinnantie 5Serco for European Space Agency (ESA), Camino bajo del Castillo, s/n, Urbanizacion Villafranca del Castillo, Villanueva de la CañadaARC Centre of Excellence for Dark Matter Particle PhysicsCentre for Astrophysics & Supercomputing Swinburne University of TechnologySchool of Physics and Astronomy Queen Mary University of London, Mile End RoadDepartment of Physics and Astronomy University of the Western Cape, BellvilleICTP South American Institute for Fundamental Research Instituto de Física Teórica Universidade Estadual PaulistaOskar Klein Centre for Cosmoparticle Physics Department of Physics Stockholm UniversityAstrophysics Group Blackett Laboratory Imperial College LondonUniv. Grenoble Alpes CNRS Grenoble INP LPSC IN2P3, 53, Avenue des MartyrsDipartimento di Fisica Sapienza Università di Roma, Piazzale Aldo Moro 2Centro de Astrofísica da Universidade do Porto, Rua das Estrelas, 4150-762 PortoInstitute of Astronomy University of Cambridge, Madingley RoadDepartment of Astrophysics University of Zurich, Winterthurerstrasse 190Dipartimento di Fisica Università degli studi di Genova INFN Sezione di Genova, Via Dodecaneso 33Theoretical astrophysics Department of Physics and Astronomy Uppsala University, Box 515Department of Physics Royal Holloway University of LondonDepartment of Astrophysical Sciences Princeton University, Peyton HallNiels Bohr Institute University of Copenhagen, Jagtvej 128Center for Cosmology and Particle Physics Department of Physics New York UniversityCenter for Computational Astrophysics Flatiron Institute, 162 5th AvenueDepartment of Astronomy University of MassachusettsUniversity of Trento, Via Sommarive 14ICTP South American Institute for Fundamental Research Instituto de Física Teórica Universidade Estadual Paulist
Postoperative Keratometry Prediction Model in Children Undergoing Bilateral Cataract Surgery With Primary Intraocular Lens Implantation
PURPOSE: To develop a model for predicting postoperative keratometry in children undergoing cataract surgery with primary intraocular lens (IOL) implantation. METHODS: The longitudinal retrospective study included all children who underwent bilateral cataract surgery and had available intraoperative and postoperative keratometry data. Variables that could influence postoperative keratometry were analyzed, and a generalized estimating equation regression model was used to predict postoperative keratometry. RESULTS: One hundred twenty eyes of 60 children were included. The mean age at surgery was 2.95 ± 2.78 years (range: 0.12 to 10.95 years), the mean age at the last follow-up was 7.25 ± 4.61 years (range: 0.50 to 20.41 years), and the mean follow-up was 2.40 ± 2.33 years (range: 0.25 to 10.37 years). Keratometry measurements were obtained in both eyes during 510 postoperative visits. The mean keratometry values before surgery and at the last follow-up were 45.32 ± 2.57 diopters (D) (range: 40.75 to 53.88 D) and 44.62 ± 2.25 D (range: 40.63 to 51.25 D), respectively. Preoperative mean keratometry, age at cataract surgery, and age at follow-up were statistically significant predictors of postoperative keratometry. The model to predict postoperative keratometry = 3.1304 + 0.9388 × (baseline keratometry) + 1.8294 × Log10 (baseline age), -1.1336 × Log10 (age at follow-up), -0.7045 × Log10 (baseline age) × Log10 (age at follow-up) was determined. The correlation between measured and estimated keratometry was R = 0.92. Using this model, a hypothetical patient who had surgery at 1 year of age with a mean keratometry value of 44.00 D would be estimated to have a keratometry value of 42.94 D at 21 years of age. CONCLUSIONS: The model is a good predictor for future keratometry after bilateral pediatric cataract surgery with an IOL implant.Storm Eye Institute Medical University of South CarolinaThe Department of Ophthalmology and Visual Sciences Universidade Federal de São PauloThe Division of Ophthalmology Surgical Specialties and Anesthesiology Department Botucatu Medical School São Paulo State University, BotucatuThe Division of Ophthalmology Surgical Specialties and Anesthesiology Department Botucatu Medical School São Paulo State University, Botucat
A Decade of Change in Peritoneal Dialysis in Brazil: Challenges and Perspectives in the Public Health System
Background/Objectives: The Brazilian Constitution defines health as a universal right and a State responsibility, with the Unified Public Health System (SUS) ensuring free access to comprehensive care, including renal replacement therapies (RRTs) such as dialysis and kidney transplantation. This study aimed to analyze trends in peritoneal dialysis (PD) usage within Brazil’s public health system over a 10-year period, focusing on geographic, demographic, and clinical changes. Methods: Using data from DATASUS and the Brazilian Society of Nephrology Dialysis Census, we analyzed PD usage and patient characteristics from 2014 to 2023. This methodology enabled an in-depth examination of shifts in RRT trends across regions and patient demographics. Results: PD usage declined from 6.5% in 2014 to 4.3% in 2023, with the steepest reductions observed in the North and Northeast regions. Usage increased in the Central-West region, while the Southeast and South experienced steady declines from 2016 to 2023. The proportion of centers offering PD decreased from 51.6% in 2014 to 37.9% in 2023. Over time, the average age of PD patients increased, as did the proportion of Brown/Black individuals receiving PD. Despite these shifts, patient serum levels of hemoglobin, parathyroid hormone, and phosphorus remained stable. Conclusions: This study highlights a relative decline in PD availability and use within Brazil’s public health system, with notable regional disparities. These findings underscore the urgent need for targeted policies to support PD infrastructure, funding, and training to ensure equitable access to RRT across the country.Department of Internal Medicine Bahiana School of Medicine and Public Health, BADepartment of Internal Medicine UNESP Universidade Estadual Paulista, SPDepartment of Internal Medicine UNESP Universidade Estadual Paulista, S
The combination of irrigation regime and water cutoff date increases the yield and water use efficiency of castor bean (Ricinus communis L.)
Castor bean (Ricinus communis L.) is a fibrous and fast-growing plant with increasing economic importance due to its ability to generate energy and in the pharmaceutical and chemical industries. This research aimed to determine the best combination of irrigation regime and irrigation cutoff date (ICD) that maximizes grain and oil yields and water use efficiency (WUE) in the castor bean hybrid AG IMA 110204. The experiments were conducted in greenhouses in randomized blocks using subdivided plots and four replicates. The plots were allocated to five irrigation regimes based on soil water tension: 20, 30, 40, 50, and 60 kPa, corresponding to I1, I2, I3, I4, and I5, respectively. The subplots show the four ICDs: 120, 130, 140, and 150 days after sowing (DAS). The I1, I2, and I3 treatments showed the highest values and did not differ in the two cycles for the following variables: weight of 100 grains, grain yield, oil yield, WUE of the grain (WUE-grains), and WUE of the oil (WUE-oil). When the irrigation cutoff was 120 DAS, in both cycles, the water regimes I1, I2, and I3 presented the highest values and did not differ in terms of grain or oil yields or WUE-grains or WUE-oil. Higher grain and oil yields with lower water demand for castor bean were obtained with the combination of 40 kPa soil water tension to define the time of irrigation and the irrigation cutoff at 120 DAS.Colombian Sugar Cane Research Center (CENICAÑA)Department of Rural Engineering and Socioeconomy School of Agronomical Sciences São Paulo State University (UNESP)Department of Horticulture São Paulo State University (UNESP)Institute of Science Engineering and Technology Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM)Department of Biosystem Engineering Luiz de Queiroz College of Agriculture/University of São Paulo (USP)Department of Plant Protection Rural Engineering and Soil São Paulo State University (UNESP)Department of Vegetable Production and Breeding School of Agronomical Sciences São Paulo State University (UNESP)Department of Rural Engineering and Socioeconomy School of Agronomical Sciences São Paulo State University (UNESP)Department of Horticulture São Paulo State University (UNESP)Department of Plant Protection Rural Engineering and Soil São Paulo State University (UNESP)Department of Vegetable Production and Breeding School of Agronomical Sciences São Paulo State University (UNESP
Euclid preparation: LVIII. Detecting extragalactic globular clusters in the Euclid survey
Extragalactic globular clusters (EGCs) are an abundant and powerful tracer of galaxy dynamics and formation, and their own formation and evolution is also a matter of extensive debate. The compact nature of globular clusters means that they are hard to spatially resolve and thus study outside the Local Group. In this work we have examined how well EGCs will be detectable in images from the Euclid telescope, using both simulated pre-launch images and the first early-release observations of the Fornax galaxy cluster. The Euclid Wide Survey will provide high-spatial resolution VIS imaging in the broad IE band as well as near-infrared photometry (YE, JE, and HE). We estimate that the 24 719 known galaxies within 100 Mpc in the footprint of the Euclid survey host around 830 000 EGCs of which about 350 000 are within the survey's detection limits. For about half of these EGCs, three infrared colours will be available as well. For any galaxy within 50 Mpc the brighter half of its GC luminosity function will be detectable by the Euclid Wide Survey. The detectability of EGCs is mainly driven by the residual surface brightness of their host galaxy. We find that an automated machine-learning EGC-classification method based on real Euclid data of the Fornax galaxy cluster provides an efficient method to generate high purity and high completeness GC candidate catalogues. We confirm that EGCs are spatially resolved compared to pure point sources in VIS images of Fornax. Our analysis of both simulated and first on-sky data show that Euclid will increase the number of GCs accessible with high-resolution imaging substantially compared to previous surveys, and will permit the study of GCs in the outskirts of their hosts. Euclid is unique in enabling systematic studies of EGCs in a spatially unbiased and homogeneous manner and is primed to improve our understanding of many understudied aspects of GC astrophysics.European Space AgencyUniversité de Strasbourg CNRS Observatoire Astronomique de Strasbourg UMR 7550Kapteyn Astronomical Institute University of Groningen, PO Box 800Department of Astrophysics/IMAPP Radboud University, PO Box 9010INAF Osservatorio Astronomico d'Abruzzo, Via MagginiEuropean Southern Observatory, Karl-Schwarzschild-Str. 2Université Paris-Saclay Université Paris Cité CEA CNRS AIMInstitut d'Astrophysique de Paris UMR 7095 CNRS Sorbonne Université, 98 bis Boulevard AragoDepartment of Mathematics and Physics E. De Giorgi University of Salento, Via per Arnesano, CP-I93INAF Sezione di Lecce Dipartimento Matematica e Fisica, Via per ArnesanoINFN Sezione di Lecce, Via per Arnesano, CP-193INAF Osservatorio Astronomico di Trieste, Via G. B. Tiepolo 11Max-Planck-Institut für Astronomie, Königstuhl 17INAF Osservatorio Astronomico di Capodimonte, Via Moiariello 16Johns Hopkins University, 3400 North Charles StreetINAF Osservatorio di Astrofisica e Scienza dello Spazio di Bologna, Via Piero Gobetti 93/3Sterrenkundig Observatorium Universiteit Gent, Krijgslaan 281 S9Institut de Recherche en Astrophysique et Planétologie (IRAP) Université de Toulouse CNRS UPS CNES, 14 Av. Edouard BelinJodrell Bank Centre for Astrophysics Department of Physics and Astronomy University of Manchester, Oxford RoadInstitute for Astronomy University of Edinburgh Royal Observatory, Blackford HillINAF Osservatorio Astrofisico di Arcetri, Largo E. Fermi 5Instituto de Astrofísica de Canarias, Calle Vía Láctea s/n, TenerifeDepartamento de Astrofísica Universidad de La Laguna, TenerifeDipartimento di Fisica Università di Roma Tor Vergata, Via della Ricerca Scientifica 1Universität Innsbruck Institut für Astro- und Teilchenphysik, Technikerstr. 25/8Dipartimento di Fisica 'E. Pancini' Universita degli Studi di Napoli Federico II, Via Cinthia 6INFN Section of Naples, Via Cinthia 6Space Physics and Astronomy Research Unit University of Oulu, Pentti Kaiteran katu 1UK Astronomy Technology Centre Royal Observatory, Blackford HillInstitute of Astronomy University of Cambridge, Madingley RoadINAF Osservatorio Astronomico di Brera, Via Brera 28IFPU Institute for Fundamental Physics of the Universe, Via Beirut 2INFN Sezione di Trieste, Via Valerio 2, TSSISSA International School for Advanced Studies, Via Bonomea 265, TSDipartimento di Fisica e Astronomia Università di Bologna, Via Gobetti 93/2INFN Sezione di Bologna, Viale Berti Pichat 6/2Max Planck Institute for Extraterrestrial Physics, Giessenbachstr. 1INAF Osservatorio Astrofisico di Torino, Via Osservatorio 20, (TO)Dipartimento di Fisica Università di Genova, Via Dodecaneso 33INFN Sezione di Genova, Via Dodecaneso 33Department of Physics 'E. Pancini' University Federico II, Via Cinthia 6Instituto de Astrofísica e Ciências do Espaço Universidade do Porto CAUP, Rua das EstrelasDipartimento di Fisica Università degli Studi di Torino, Via P. Giuria 1INFN Sezione di Torino, Via P. Giuria 1INAF IASF Milano, Via Alfonso Corti 12David A. Dunlap Department of Astronomy & Astrophysics University of Toronto, 50 St George StreetCentro de Investigaciones Energéticas Medioambientales y Tecnológicas (CIEMAT), Avenida Complutense 40Port d'Informació Científica, Campus UAB, C. Albareda s/n, BellaterraInstitute for Theoretical Particle Physics and Cosmology (TTK) RWTH Aachen UniversityINAF Osservatorio Astronomico di Roma, Via Frascati 33Dipartimento di Fisica e Astronomia 'Augusto Righi' Alma Mater Studiorum Università di Bologna, Viale Berti Pichat 6/2European Space Agency ESRIN, Largo Galileo Galilei 1, FrascatiESAC ESA, Camino Bajo del Castillo, s/n, Urb. Villafranca del Castillo, Villanueva de la CañadaUniversité Claude Bernard Lyon 1 CNRS IN2P3 IP2I Lyon UMR 5822Institute of Physics Laboratory of Astrophysics Ecole Polytechnique Fédérale de Lausanne (EPFL) Observatoire de SauvernyUCB Lyon 1 CNRS IN2P3 IUF IP2I Lyon, 4 Rue Enrico FermiMullard Space Science Laboratory University College London, Holmbury St Mary, SurreyDepartamento de Física Faculdade de Ciências Universidade de Lisboa, Edifício C8, Campo GrandeInstituto de Astrofísica e Ciências do Espaço Faculdade de Ciências Universidade de Lisboa, Campo GrandeDepartment of Astronomy University of Geneva, Ch. d'Ecogia 16INAF Istituto di Astrofisica e Planetologia Spaziali, Via del Fosso del Cavaliere, 100INFN Padova, Via Marzolo 8School of Physics HH Wills Physics Laboratory University of Bristol, Tyndall AvenueUniversitäts-Sternwarte München Fakultät für Physik Ludwig-Maximilians-Universität München, Scheinerstrasse 1Aix-Marseille Université CNRS IN2P3 CPPMIstituto Nazionale di Fisica Nucleare Sezione di Bologna, Via Irnerio 46FRACTAL S.L.N.E., Calle Tulipán 2, Portal 13 1AINAF Osservatorio Astronomico di Padova, Via dell'Osservatorio 5Institute of Theoretical Astrophysics University of Oslo, PO Box 1029 BlindernLeiden Observatory Leiden University, Einsteinweg 55Jet Propulsion Laboratory California Institute of Technology, 4800 Oak Grove DriveDepartment of Physics Lancaster UniversityFelix Hormuth Engineering, Goethestr. 17Technical University of Denmark, Elektrovej 327Cosmic Dawn Centre CopenhagenDepartment of Physics Helsinki Institute of Physics University of Helsinki, Gustaf Hällströmin katu 2Université de Genève Département de Physique Théorique Centre for Astroparticle Physics, 24 Quai Ernest-Ansermet, 4Department of Physics University of Helsinki, PO Box 64Helsinki Institute of Physics University of Helsinki, Gustaf Hällströmin katu 2European Space Agency ESTEC, Keplerlaan 1NOVA Optical Infrared Instrumentation Group ASTRON, Oude Hoogeveensedijk 4Dipartimento di Fisica 'Aldo Pontremoli' Università degli Studi di Milano, Via Celoria 16INFN Sezione di Milano, Via Celoria 16Universität Bonn Argelander-Institut für Astronomie, Auf dem Hügel 71INFN Sezione di Roma Dipartimento di Fisica, Piazzale Aldo Moro, 2, Edificio G. MarconiAix-Marseille Université CNRS CNES LAMDipartimento di Fisica e Astronomia 'Augusto Righi' Alma Mater Studiorum Università di Bologna, Via Piero Gobetti 93/2Department of Physics Centre for Extragalactic Astronomy Durham University, South RoadDepartment of Physics Institute for Computational Cosmology Durham University, South RoadUniversité Côte d'Azur Observatoire de la Côte d'Azur CNRS Laboratoire Lagrange, Bd de l'Observatoire, CS 34229, Cedex 4Université Paris Cité CNRS Astroparticule et CosmologieInstitut d'Astrophysique de Paris, 98 bis Boulevard AragoInstitut de Física d'Altes Energies (IFAE) The Barcelona Institute of Science and Technology, Campus UAB, BellaterraSchool of Mathematics and Physics University of Surrey SurreySchool of Mathematics Statistics and Physics Newcastle University, Herschel BuildingDepartment of Physics and Astronomy University of Aarhus, Ny Munkegade 120Space Science Data Center Italian Space Agency, Via del Politecnico sncCentre National d'Etudes Spatiales Centre spatial de Toulouse, 18 Avenue Edouard Belin, Cedex 9Institute of Space Science, Str. 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Grenoble Alpes CNRS Grenoble INP LPSC-IN2P3, 53, Avenue des MartyrsDipartimento di Fisica Sapienza Università di Roma, Piazzale Aldo Moro 2Centro de Astrofísica da Universidade do Porto, Rua das EstrelasDepartment of Astrophysics University of Zurich, Winterthurerstrasse 190Dipartimento di Fisica Università degli studi di Genova INFN Sezione di Genova, Via Dodecaneso 33Department of Physics and Astronomy Uppsala University, Box 515Department of Physics Royal Holloway University of LondonDepartment of Astrophysical Sciences Princeton University, Peyton HallNiels Bohr Institute University of Copenhagen, Jagtvej 128Center for Cosmology and Particle Physics Department of Physics New York UniversityCenter for Computational Astrophysics Flatiron Institute, 162 5th AvenueDepartment of Physics and Astronomy University of British ColumbiaICTP South American Institute for Fundamental Research Instituto de Física Teórica Universidade Estadual Paulist
Municipal government schools as a continuing education tool for work: transforming city administrators into citizenship pedagogues
O material aqui apresentado refere-se ao relatório de atividades do projeto de pesquisa de pós-doutorado intitulado - Projeto: “Escolas de Governo Municipais como ferramenta de educação continuada para o trabalho: transformando administradores de cidades em pedagogos da cidadania.”, Projeto nº 5.213/2024. A pesquisa foi realizada durante o período de abril de 2024 até abril de 2025 com a supervisão do Professor Doutor José Luís Bizelli.
A investigação originou-se da discussão a partir da Emenda Constitucional nº 19/98, o princípio da eficiência, entabulado em seu artigo 37, caput, passou a integrar ao ordenamento jurídico da Administração Pública. Por este princípio, se pressupõe que a atividade administrativa deve ser exercida com presteza, perfeição e rendimento funcional, com enfoque gerencial e voltada para o controle dos resultados na atuação estatal com implementação de gestão por competências, uma vez que as demandas da sociedade são cada vez maiores e os recursos públicos por outro lado mais escassos.
O relatório a seguir apresenta as referências bibliográficas sobre a temática estudada, o caminho metodológico para coleta de dados, as análises preliminares da pesquisa, além da produção científica do período, o projeto de lei e Minuta de Projeto Pedagógico da Escola de Governo nos moldes propostos.Verifica-se que a questão da eficiência na Administração foi incorporada ao Ordenamento Jurídico Brasileiro a partir da Emenda Constitucional nº 19/98. destacando a necessidade de ações administrativas ágeis e eficazes. Este princípio enfatiza não apenas a atuação do agente público, mas também a estrutura organizacional da administração, buscando resultados na prestação de serviços. A escassez de mão de obra qualificada e a alta rotatividade de servidores representam desafios permanentes, tornando essencial a valorização profissional e a capacitação contínua. A nova Lei de Licitações (Lei nº 14.133/2021) reforça a importância da gestão por competências e do profissionalismo dos agentes públicos. Neste contexto, a implantação de Escolas de Governo surge como uma estratégia para promover a educação continuada dos servidores, garantindo que estejam preparados para atender às demandas da sociedade. Essas instituições devem focar na formação de cidadãos conscientes e agentes públicos inovadores, transformando a cultura da administração e fortalecendo a profissionalização no serviço público.It appears that the issue of efficiency in Administration was incorporated into the Brazilian Legal System as of Constitutional Amendment No. 19/98. highlighting the need for agile and effective administrative actions. This principle emphasizes not only the performance of the public agent, but also the organizational structure of the administration, seeking results in the provision of services. The shortage of qualified labor and the high turnover of employees represent permanent challenges, making professional development and continuous training essential. The new Tenders Law (Law nº 14,133/2021) reinforces the importance of management by skills and the professionalism of public agents. In this context, the implementation of Government Schools appears as a strategy to promote the continued education of civil servants, ensuring that they are prepared to meet the demands of society. These institutions must focus on training conscious citizens and innovative public agents, transforming the culture of administration and strengthening professionalization in the public service.5.213/202
Electrical stimulation to improve meat quality: Factors at interplay, underlying biochemical mechanisms and a second look into the molecular pathways using proteomics
Ensuring consistent beef eating quality is paramount for meeting consumer demands and sustaining the meat industry. Electrical stimulation (ES) is a post-slaughter intervention used to accelerate post-mortem glycolysis, to avoid cold shortening, to control the tenderization rate of meat through sophisticated physical, chemical and biochemical mechanisms including proteolysis, to improve beef tenderness and to achieve normal pHu that might lead to positive impact on color. This review comprehensively examines the multifaceted effects of ES on beef quality, encompassing factors and settings influencing its efficacy and the underlying biochemical mechanisms revealed using traditional biochemistry methods. It then delves into the molecular pathways modulated by ES, as unveiled by muscle proteomics, aiming to provide a second look and an unprecedented understanding of the underlying biochemical mechanisms through an integrative proteomics analysis of low-voltage ES (LVES) proteomics studies. The proteins changing as a result of ES were gathered in a compendium of 67 proteins, from which 14 were commonly identified across studies. In-depth bioinformatics of this compendium allowed a comprehensive overview of the molecular signatures and interacting biochemical pathways behind electrically stimulated beef muscles. The proteins belong to interconnected molecular pathways including the ATP metabolic process and glycolysis, muscle structure and contraction, heat shock proteins, oxidative stress, proteolysis and apoptosis. Understanding the intricate interplay of molecular pathways behind ES could improve the efficiency of beef production, ensuring consistent meat quality and meeting consumer expectations. The integrative analysis approach performed in this study holds promise for the meat industry's sustainability and competitiveness.PEGASE INRAE Institut AgroLacombe Research and Development Centre Agriculture and Agri-Food CanadaAustralian Capital TerritorySchool of Veterinary Medicine and Animal Science São Paulo State UniversityLaboratory of Meat Processing and Quality Control College of Food Science and Engineering Shandong Agricultural University, ShandongDepartment of Agriculture Food Natural Resources and Engineering (DAFNE) University of FoggiaSchool of Veterinary Medicine and Animal Science São Paulo State Universit
A history of teaching and learning at the Faculty of Medicine of Marília - FAMEMA - in medical and nursing education
Trata-se de tese decorrente de pesquisa de doutorado, fundamentada nos pressupostos de análise da História Cultural e da História Oral, com o objetivo central de identificar, analisar e interpretar aspectos da trajetória histórica do ensino nos cursos médicos, Medicina e Enfermagem, da Faculdade de Medicina de Marília – FAMEMA, entre 1967 e 1997. A hipótese norteadora da pesquisa é a de que o ensino médico em vários momentos da trajetória histórica dos cursos ofertados pela FAMEMA foi pautado pela ênfase técnica em seus processos, em consonância com a formação de profissionais em atenção integral à saúde no Brasil. No entanto, o ápice de seus processos formativos teria sido a década de 1990, correspondente a criação do SUS, Sistema Único de Saúde, mediante a Lei nº 8080, assinada em 19/9/1990, e à implantação de um novo currículo mínimo do curso de Enfermagem e de reformulação do modelo educacional do curso de Medicina, como mencionado. Isso porque, com o SUS, a ideia fundante foi de busca e garantia “de acesso integral, universal e gratuito para toda a população do país [...] um direito de todos os brasileiros, desde a gestação e por toda a vida, com foco na saúde com qualidade de vida, visando a prevenção e a promoção da saúde.” Nesse sentido, a trajetória histórica do ensino nos cursos médicos da FAMEMA, centralmente entre 1967 e 1997, teria, portanto, contribuído para um perfil específico de formação de seus egressos, atrelado ao campo da pesquisa, em busca de reflexões sobre e soluções científicas para questões da saúde da população brasileira, ressaltando os aspectos humanos da formação médica, incluindo, sobretudo, as preocupações com os aspectos didático-pedagógicos para uma formação médica ampla e integral. Os documentos que compõem o corpus da investigação, base da estrutura da investigação, foram localizados no acervo local da FAMEMA, relacionados ao funcionamento dos seus cursos. Nesse sentido, procedeu-se à articulação da temática numa perspectiva plural, com os elementos de documentos legais e de documentos produzidos na e pela instituição. Tratou-se de uma pesquisa histórica, quanto à abordagem, e documental quanto às fontes. Ao final, foi possível compreender que a FAMEMA vivenciou momentos de intensos debates políticos e questionamentos sobre as estratégias de ensino e aprendizagem, caminhando como uma via de mão dupla com as necessidades dos estudantes, a partir do contexto e realidade local das épocas em que ocorriam os marcos históricos. Nesse sentido, foi necessário mudanças paradigmáticas, como a adoção de metodologias de ensino e aprendizagem e da perspectiva da Medicina Centrada na Pessoa, perspectivas essas para um ensino médico no Brasil, segundo a premissa de “abertura de muros para a comunidade”, e na valorização da participação social no processo de planejamento e organização do sistema e do cuidado em saúde, com o Sistema Único de Saúde – SUS.This is a thesis resulting from doctoral research, based on the assumptions of analysis of Cultural History and Oral History, with the main objective of identifying, analyzing and interpreting aspects of the historical trajectory of teaching in the medical courses, Medicine and Nursing, of the Faculty of Medicine of Marília – FAMEMA, between 1967 and 1997. The guiding hypothesis of the research is that medical education at various times in the historical trajectory of the courses offered by FAMEMA was guided by the technical emphasis on its processes, in line with the training of professionals in comprehensive health care in Brazil. However, the apex of their training processes would have been the 1990s, corresponding to the creation of the SUS, Unified Health System, through Law No. 8080, signed on 9/19/1990, and the implementation of a new minimum curriculum for the Nursing course and the reformulation of the educational model of the Medicine course, as mentioned. This is because, with the SUS, the founding idea was to seek and guarantee "full, universal and free access for the entire population of the country [...] a right of all Brazilians, from pregnancy and throughout life, with a focus on health with quality of life, aiming at prevention and health promotion." In this sense, the historical trajectory of teaching in FAMEMA's medical courses, centrally between 1967 and 1997, would have, therefore, contributed to a specific profile of training of its graduates, linked to the field of research, in search of reflections on and scientific solutions to health issues of the Brazilian population, emphasizing the human aspects of medical training, including, above all, the concerns with the didactic-pedagogical aspects for a broad and comprehensive medical education. The documents that make up the corpus of the investigation, the basis of the structure of the investigation, were located in the local collection of FAMEMA, related to the functioning of its courses. In this sense, the theme was articulated in a plural perspective, with the elements of legal documents and documents produced in and by the institution. It was a historical research, in terms of approach, and documentary research in terms of sources. In the end, it was possible to understand that FAMEMA experienced moments of intense political debates and questions about teaching and learning strategies, walking as a two-way street with the needs of students, from the context and local reality of the times in which the historical milestones occurred. In this sense, paradigmatic changes were necessary, such as the adoption of teaching and learning methodologies and the perspective of Person-Centered Medicine, perspectives for medical education in Brazil, according to the premise of "opening walls for the community", and valuing social participation in the process of planning and organizing the system and health care, with the Unified Health System – SUS.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)CAPES: 00