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DIFFERENTIATION BETWEEN PORCINE AND BOVINE GELATIN IN CAPSULE SHELLS BASED ON AMINO ACID PROFILES AND PRINCIPAL COMPONENT ANALYSIS
Get PDFGelatin used for capsule shells can be derived from porcine origin. Some religion like Islam prohibited their followers to consume any products containing porcine derivatives including porcine gelatin in the products. Consequently, some rapid and reliable techniques are continuously developed for detection of porcine gelatin in some pharmaceutical products like capsule shells. The aim of this study was to evaluate the possibility to use amino acid profile in combination with chemometrics of principal component analysis for detection and classification between gelatin in capsule derived from porcine and bovine. Based on score plot of first principal components (PC1) and second principal components (PC2), porcine and bovine gelatins in capsule could be apparently distinguished
INFLUENCE OF Morinda citrifolia, L. FRUIT EXTRACTAS ADJUVANT ON IG-Y PRODUCTION RAISED IN LAYING CHICKENS AGAINST AVIAN INFLUENZA VACCINE
Get PDFImmunized avian with vaccine, produces specific antibody in the serum as well as in the egg yolk. An adjuvant is used to augment the effects of a vaccine by stimulating the immune response. Morinda citrifolia, L., especially the fruit contains of some chemical compounds such as polysaccharide, scopoletin, damnacanthal, proxeronine and proxeroninase. All those of active compounds, are soluble in different solvents and have different activities. Some of those compounds have adjuvant activity. The aim of our study was to observe the capability of M.citrifolia fruit extracts as adjuvant to enhance the specific antibody (IgY) production in immunized laying chickens Lohmann strain (28 weeks old) with a commercially available avian influenza (H5N2) vaccine. To the groups (@6) of laying chickens were orally administered once a day, through out of the study, with n-hexane (group Idivided ino 3 sub groups), ethanolic (group IIdivided into 3 subgroups) and aqueous extract (group IIIdivided into 3 subgroups) of M.citrifolia (prepared in capsules) on dose of 29 mg58 mgand 116 mg/chicken/day, respectively, and group IV as plasebo control and group V as normal control. All of the groups were induced with avian influenza vaccine, except the normal control. Eggs of 3, 6, and 10 weeks after immunized, were collected. Isolation of IgY was performed by repeated polyethylene glycol 6000 precipitation steps. IgY obtained was analyzed by indirect ELISA method. The serum was tested for antibody specificity against the influenza H5N2 virus by hemagglutination-inhibition (HI) method. The result of this study showed that the dose of 58 mg/chicken/day of aqueous extract of M.citrifolia fruit had an optimal capability to enhance specific antibody (IgY) as well as IgG serum production against avian influenza (H5N2) vaccine
IDENTIFICATION OF SAFETY ALERT BY MONITORING ANALYTICAL PARAMETERS AND HIGH-RISK DRUGS
Get PDFEarly detection of adverse drug reactions (ADR) increases patient safety. Our objective was to identify ADR by monitoring laboratory parameters and high-risk drugs. We carried out a two-month prospective observational study in a Internal Medicine Department, with daily recording of drugs prescribed and the following parameters: Na, K, Ca, serum creatinine, glomerular filtration rate (GFR), INR, glucose, haemoglobin, platelets, ALT, AST, bilirubin, GGT, alkaline phosphatase, TSH, T4, and blood digoxin. High-risk drugs were closely monitored. 52 patients included, of whom 46.2% experienced an ADR. We opserved an association with drugs in 25.5%, as follows: reduction in GFR, 26.9% (associated with loop diuretics [41. 7%], angiotensin-converting enzyme [ACE] inhibitors [33.3%], angiotens1n II receptor blockers [ARB] [16.6%], and anti-diabetic drugs [8.3%])hypokalemia, 22.3% (associated with loop diuretics [50.0%], potassium-free fluid [37.5%], and salbutamol [12.5%])hyperkalemia, 14.4% (associated with ACE inhibitors [60.0%] and ARB [40.0%])INR out of range, 10.8% (associated with drug interactions [66.7%])hyperglycemia, 8.1% (associated with corticosteroids [66.7%] and anti-diabetic drugs [33.3%])and other conditions, 18.8%. We conclued that patient safety could be improved by implementing warnings in electronic prescriptions jn cases of a decrease in GFR or modification of potassium levels in patients who are prescribed loop diuretics, ACE inhibitors, or ARBs
PROTESA MAKSILO FASIAL KERANGKA LOGAM KOMBINASI BAHAN TERMOPLASTIK PADA DEFEK KELAS II ARAMANY PASCA HEMIMAXILLECTOMY
Get PDFLatar Belakang: Tindakan bedah hemimaxilectomy dapat menyebabkan terjadinya cacat pada w,ajah, gangguan fungsi bicara, penelanan, pengunyahan, estetik serta kejiwaan penderita dan dapat menimbulkan masalah pada rehabilitasinya. Tujuan: Laporan kasus untuk mengetahui pengaruh penggunaan protesa maksilofasial kerangka logam kombinasi bahan termoplastik pada defek kelas IIAramany terhadap estetik, retensi, dan stabilisasi protesa. Kasus: Seorang wan ita umur 58 tahun telah dilakukan hemimaxilectomysejak setahun yang lalu. Defekkelas IIAramany, sebagian besar gigirahang atas sudah tidak ada, gigi yang masih ada 11, 13, dan 17. Dilakukan pemeriksaan, subyektif, obyektif dan radiografi, kemudian dilakukan pencetakan dengan menggunakan bahan cetak hidrokoloid irreversible, kemudian proses laboratorium pembuatan kerangka logam kemudian MMR, penyusunan gigi, try in gigi tiruan malam, kemudian dilakukan proses laboratorium bahan termoplastik, dan insersi protesa. Pada insersi diperhatikan retensi stabilisasi dan oklusi. Pembuatan protesa kerangka logam kombinasi bahan termoplastik pada defek kelas II Aramay merupakan pilihan yang tepat. Kesimpulan: dapat menghasilkan retensi, stabilisasi, oklusi dan estetik yang baik. Maj Ked GiJuni 201219(1): 89-9
PENGEMBANGAN ".MADRASAH BERPARADIGMA PEMBANGUNAN BERKELANJUTAN
Get PDFThis study aims to discaver learning inrwvation education for sustainable development (EfSD) that can bring sustainability messages to the resource values, environmental, social and cultural. EfSD can teach morality to human beings as actors in their environment to always be careful and wise in every activity that uses natural resources. The use of natural resources for the development is not only to meet short-term economic needstherefore it is necessary to establish management strategies that ensure sustainability, fairness, and effidency. Efforts to achieve these strategies are mediated by debriefing people with environment ethical values which in this case implemented in the children education. The results of this research explain: (1) developing sustainable development paradigmatic learning inrwvation must comply with the talents of students, which can be done by developing KTSP (curriculum of unit-level education)(2) socia-cultural values conservation become the basis to achieve sustainable development paradigm(3) innovation towards sustainable development paradigm variation for each school background. This innovation is then expected could guarantee the realization of sustainable development paradigm in formal educationfor the sake of inter generation environment conservation.
Keywords: islamic education, madrasah and sustainable development
Penelitian bertujuan untuk menemukan inovasi pendidikan untuk pembangunan berkelanjutan (EfSD) yang dapat membawa pesan-pesan keberlanjutan terhadap nilai-nilai sumberdaya, lingkungan hidup, dan sosial budaya. EfSD dapat mengajarkan moralitas kepada umat manusia untuk selalu berhati-hati dalam setiap aktivitas yang bersinggungan dengan lingkungan. Pengguna.an sumberdaya alam untuk pembangunan tidak hanya menitikberatkan pada ekonomi jangka.pendek, namun juga hams menekankan pada aspek keberlanjutan, keadilan, dan efisiensi. Usaha untuk mencapai strategi tersebut hams diberikan dalam pendidikan anak. Hasil penelitian ini menunjukkan, (1) pengembangan inovasi pembelajaran berparadigma pembangunan berkelanjutan harus sesuai dengan talenta siswa, yang dapat dilakukan dengan mengembangkan K1BP (kurikulum tingkat satuan pendidikan)(2) pelestarian nilai sosial budaya menjadi basis untuk menuju paradigma pembangunan berkelanjutan(3)inovasi menuju paradigma pembangunan berkelanjutan bervariasi untuk masing-masing latar belakang sekolah. Inovasi tersebut selanjutnya diharapkan dapat menjadi jaminan terwujudnya paradigma pendidikan pembangunan berkelanjutan pada jalur pendidikan formal, demi kelestarian lingkungan hidup yang berkesinambungan antargenerasi.
Kata kunci: Pendidikan Islam, Madrasah dan Pembangunan Berkelanjuta
PENINGKATAN PROTEIN TEPUNG BERAS MELALUI PROSES ENZIMATIS DANPENGE NGANSEMPROT
Get PDFThe purpose of this research is to produce HPRF of dry and wet milled rice flour through enzymatic process by a-amylase and spray-drying. The steps of research include determination of the concentration of rice flour suspension, determination of the enzyme concentration, producing slurry, and spray-drying. The result show that enzymatic process of dry and wet milled rice flour required concentration of suspension 10% and 20% respectively with the addition of amylase 0,1% (v/v). Enzymatic process takes 45 minutes to achieved DE 30% :t 2%. Theyield of powder produced from dry and wet milled rice flour based on raw material are 7,77% and 11,6%, with protein content 37,35% and 22,18% respectively. The conclusion is the production of HPRF through the stages of dry-milling wasbetter than wet-milling rice flour in term of both technical as well as result obtaine
PENGEMBANGAN WIRELESS SENSOR NETWORK UNTUK APLIKASI HOME CONTROLLING
Get PDFHome controller, is a system to control home appliances or building, such as lighting systems, and household appliances. The operation of the equipment controlled by an electronic switch, home system controller will control the switches via IP-based controller unit. Application of home media controller with cables on existing installation system on a home or building would be impractical because they have to change the existing system installation, it would require an expensive cost. TechnologyWSN(Wireless Sensor Network), as analternative network, whichcan replace the cable network, as well as PLC (Power Line Carrier) technology already exists. Besides the above technical considerations, the implementation of this controlling system home business is intended to enhance and enrich the utility speedy network service types of PT TelekomunikasiIndonesia Tbk., Which is a network of public Internet access.WSNarchitecture, consisting of WSNgateway, WSNnodes, and router.WSNWSNgateway function to connect the WSNnetwork with a network computer connected to the internet. WSNnode is a system on a chip (Sac: system on chip), which consists of RF and microcontroller systems that have multiple input ports, output ports and several types of sensors. WSN gateway and the nodes are programmable, WSN node is programmed as a tool that can control the electronic switch to turn off or turn on lights and other household appliances. WSN Gateway serves to control the number of WSNnodes through RF (Radio Frequency) and connect to the Internet network. The application is designed based on WSN Gateway WEB, so it can be controlled with a Webbrowser remotely over the internet.The results of this study is a frame work, to build a home system controlling applications, devices and home controller API and wireless sensor devices that connect with sensors and input/output devices
THE POLITICS OF BELONGING: PLUNDERING THE LOCAL, CLAIMING THE GLOBAL
Get PDFGlobal dan lokal seringkali ditempatkan dalam posisi yang saling berseberangan dan saling menghapuskan. Ketika globalisasi semakin intensif orang membayangkan adanya proses kepunahan segala sesuatu yang bersifat lokal. Proses migrasi yang semakin intensif ke kota-kota besar dan pada saat bersamaan internalisasi nilai-nilai baru ke dalam tatanan masyarakat lokal melalui perangkat telekomunikasi dibayangkan akan menyebabkan hilangnya lokalitas. Pada intinya. globalisasi menyebabkan alienasi masyarakat lokal pada sistem nilai dan kulturnya sendiri. Namun beberapa ahli dalam studi globalisasi juga memperlihatkan tumbuhnya genre-genre baru kebudayaan global yang jelas-jelas memperlihatkan akar lokalnya. Migrasi ke kota tidaklah serta merta menyebabkan orang kehilangan kontak dengan desa asalnya. Secara berkala orang kota terse but terlibat aktif mensponsori ritual-ritual komunitas di daerah asalnya untuk memperjuangkan status-status sosial baru. Hal ini menunjukkan bahwa proses global dan lokal bukanlah hal yang selalu beroposisi, melainkan bersifat komplementer. Inilah yang menyebabkan lokalitas tidak akan pernah terhapuskan, bahkan proses globalisasi dalam beberapa hal justru merevitalisasi lokalitas meskipun tidak dalam bentuk dan nilai awalnya
PENERAPAN NORMA DAN ASAS-ASAS HUKUM ADAT DALAM PRAKTIK PERADILAN PERDATA
Get PDFThis research was descriptive research. Secondary and primary data were analysed qualitatively. The result of the research shows that mostly, the application of adat law norm and principles appear in the domain of private, contract, marital, and inheritance law. The adat law norms which arefrequently used asjudge considerations are the right of spouse on the matrimonial property, the guardian of a child under his mother, and the status of ex-wife as the heir of her former husband. Wealso identify a number of adat law principles, which include the clear (terang), cash (tunai), real (konkret) andfamiliarity (kekeluargaan). Application of adat law is necessary owing to the normative legislative obligation. In practice, judges need to ensure that adat law norms are consistent with the applicable civil procedure.
Penelitian ini bersifat deskriptif, yaitu melukiskan fakta obyek penelitian. Data primer dan sekunder dianalisis seeara kualitatif. Hasil penelitian menunjukkan bahwa norma hukum adat yang dijadikan dasar pertimbangan putusan hakim adalah istri berhak atas harta bersama, anak keeil diasuh ibu yang bercerai, dan istri adalah ahliwaris mendiangsuaminya.Asas hukum adat yang mendasari putusan hakim meneakup asas terang, tunai, konkrit dan kekeluargaan. Alasan hakim menerapkan norma dan asas hukum adat dikarenakan kewajiban normatif dari undang-undangdan dalamupaya membentuk yurisprudensi.Namun, praktiknya tidak mudah sehingga hakim hams melakukan harmonisasi ke dalam hukum acara positif
KEBIJAKAN PIDANA MATI TERHADAP PEREMPUAN
Get PDFThe government must accord special legal protection for pregnant and lactatingfemale prisoners. Act Nr. 2/Pnps/J 964 has been stipulated to the effect of regulating capital punishment to women. However, the Act does not yet reflect the sense ofjustice, humanity, and protection. Capital punishment for women must be reviewed. In a number of countries capital punishment for women has been abolished. In addition, several international legal instruments calling for abolishment of capital punishment for women are extant. In addition, the review of capital punishment for women stands upon the spirit that the implementation of capital punishment must not be applied too broadly in order to ensure that the objective of punishment would not go in a wrong way.
Perlindungan hukum dan pengayoman terhadap perempuan pelaku tindak pidana khususnya yang sedang hamil dan menyusui, tidak dapat disamaratakan dengan laki-laki. Undang-Undang Nomor 2/ Pnps/1964, telah mengatur nonna pelaksanaan pidana mati terhadap perempuan, akan tetapi aturan ini belum mencenninkan rasa keadilan, kemanusiaan, dan perlindungan. Kebijakan pidana mati terhadap perempuan di Indonesia sudah selayaknya ditinjau ulang. Di banyak negara ditemukan penerap~npidana mati secara terbatas dengan menghilangkan pidana mati khusus terhadap perempuan. Selain itu, berbagai ketentuan-ketentuan hukum intemasional juga cenderung melarang pidana mati untuk perempuan. Peninjauan kebijakan pidana mati terhadap perempuan ini juga didasari semangat bahwa penerapan hukum pidana tidak boleh disamaratakan karena malah akan menjadi pengancam bagi tujuan hukum pidana itu sendiri