Jurnal Kesehatan Andalas
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Penguatan Intervensi Perilaku terhadap Pencegahan HIV pada Kelompok Berisiko: Sistematik Review
Full text linkIntervensi perilaku sangat penting dilakukan dalam pencegahan HIV sebagai intervensi dalam upaya meningkatkan status kesehatan. Tujuan: Mengetahui bentuk intervensi perilaku untuk mengukur outcome dari pencegahan terjadinya HIV terutama pada kelompok berisiko. Metode: Electronic database dari jurnal yang telah dipublikasikan melalui ProQuest, PubMed., dan ScienceDirect. Hasil: Review dari delapan jurnal yang telah dipilih menyatakan bahwa intervensi perilaku memberi pengaruh terhadap peningkatan pengetahuan tentang HIV/AIDS, konseling bagi kelompok dengan rIsiko tinggi seperti pada Lelaki Seks dengan Lelaki (LSL) dan juga pelaksanaan tes HIV atau yang dikenal dengan Voluntary Counseling and Testing (VST). Instrumen penelitian yang digunakan untuk mengukur behavioral intervention pada penelitian kuantitaif yakni kuesioner, instrumen berbasis komputer dan internet seperti sosial media, sedangkan pada penelitian kualitatif menggali informasi dengann indepth interview dan Focus Group Discussion (FGD). Hasil penelitian menunjukkan bahwa penguatan intervensi perilaku dalam pencegahan HIV memberi manfaat dalam peningkatan pengetahuan, persepsi dan perilaku pencegahan HIV positif, serta penurunan stigma bagi ODHA. Simpulan: Penguatan intervensi perilaku dapat mencegah terjadinya HIV pada kelompok berisiko sehingga dapat meningkatkan derajat kesehatan.Kata kunci: intervensi perilaku, pencegahan HIV, LS
Perbandingan Tingkat Keparahan Infeksi Sekunder Virus Dengue pada Keempat Serotipe di Indonesia: Systematic Review
Full text linkSecondary infection with the dengue virus causes mild to severe manifestations. The distribution of dengue virus serotypes varies in various areas and can change over time. There are four dengue serotypes, namely DENV-1, DENV-2, DENV-3 and DENV-4. Objectives: To knew the distribution of virus serotypes in an area and determined the pathogenesis of the disease, which can cause severe manifestations in patients with secondary infections. Methods: The data taken is the severity of secondary infections and dengue serotypes. The literature search was performed on PMC and Cochrane. Search criteria were performed using keywords (secondary infection * OR secondary dengue infection *) AND (Dengue Virus * OR Dengue Infection * OR Dengue * OR DENV) AND (Serotype * OR Serogroup) AND (severe dengue * OR severity * OR severity of illness indexs * OR dengue fever * OR dengue haemorrhage fever * OR dengue shock syndrome * OR DF * OR DHF * OR DSS *) AND (Indonesia *). Results: Literature study search found 387 literature with five studies conducted the analysis. From the results of the analysis, it was found that secondary infections were more common in patients with recurrent dengue infection with serotype 2 (DENV-2), serotype 3 (DENV-3) and serotype 4 (DENV-4). Conclusion: Secondary infection of dengue virus serotype 2 (DENV-2) and serotype 3 (DENV-3) can cause severe dengue infection.Keywords: Â Dengue Virus, Indonesia, Secondary Infection, Serotype, Severit
Coronavirus Disease 2019 in Chronic Kidney Disease: A Case Report
Full text linkThe COVID-19 pandemic has caused substantial morbidity and mortality worldwide. Older patients, male gender and those with preexisting comorbidities such as chronic kidney disease are reported to be more likely infected with SARS CoV-2 and are at higher risk of severe illness or death. It has been reported a 24 years old male was admitted to the hospital with shortness of breath, coughing, fever and paleness. The history of contact with confirmed COVID-19 cases was unclear. The patient works as a security officer. A history of hypertension is present. Laboratory results showed hemoglobin 7 g/dl, ureum 261 mg/dl, and creatinine 22,9 mg/dl. On the second day of admission, the patient experience increased shortness of breath, decreased consciousness and epistaxis. From the result of the nasopharyngeal swab, the patient tested positive for COVID-19 and was given Oseltamivir 75mg. The patient is prepared for hemodialysis, which was performed in the isolation room. After hemodialysis, the patient's condition improved with decreased shortness of breath and increased of consciousness. The patient comes out from the isolation room and discharges home in good condition. Antiviral therapy in CKD patients with Covid-19 infection requires dose adjustment. Immediate hemodialysis is required in patients with CKD and coexisting COVID-19 infection to improve the patient's condition. Prompt management for patients with CKD and COVID-19 will reduce the risk of mortality.Keywords: Â COVID-19, chronic kidney disease, hemodialysi
Gambaran Drug Related Problems (DRPs) Terapi Farmakologi Pasien ISPA Pediatrik di Rumah Sakit PKU Muhammadiyah Gamping Yogyakarta
Full text linkAcute Respiratory Infection has become the major cause of death in children in developing countries. There were about 11.9 million episodes of severe acute lower respiratory infection that resulted in hospital admission in young children worldwide. The method of drug administered was the common Drug-Related Problems found in young children. Objectives: To evaluated Drug-Related Problems of Acute Respiratory Infection drug therapy in pediatric patients. Methods: Ninety-four pediatric patients were included in this study. Drug therapy data were obtained from medical records from January 2018 until July 2019, as this study was using a retrospective method. Drug-Related Problems of drug therapy were analyzed based on the Cipolle classification system. Results: Prevalence of female and male patients are in the same number (50%) with the highest prevalence on 2-11 years (72.34%) in young children. The number of Drug-Related Problems was found about 61.49% from 148 numbers of used drugs with improper drug selection as the major Drug Related Problems (51,65%)Â followed by drugs without indication and underdose by 23.08% and 15.38%, respectively.Keywords: Â acute respiratory infection, hospital, pediatrics, pharmacologic therap
Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue
Full text linkDengue Hemorrhagic Fever diagnosis is supported by examining Blue Plasma Lymphocytes and C-Reactive Protein, in which Blue Plasma Lymphocytes can distinguish Dengue and Non-Dengue infections. At the same time, the C-Reactive Proteins are used to see the presence of inflammation due to infections such as Dengue Virus infection. Objectives: To analyzed the correlation of the number of Blue Plasma Lymphocytes with C-Reactive Protein (CRP) levels in Dengue Hemorrhagic Fever patients. Methods: This study was analytical observational research with a cross-sectional design. The sample used was a patient diagnosed with DHF with a positive Nonstructural protein 1 (NS1) or Rapid Diagnostic Test (RDT) IgG/IgM result. The data was collected and analyzed using Spearman's rank statistical test. Results: The average number of Blue Plasma Lymphocytes in positive samples was 8%, with the number of negative results, namely 4 (13.33%) samples and 26 (86.67%) samples with positive Blue Plasma Lymphocyte results. The average level of C–Reactive Protein in the positive samples was 29.36 mg/L, with results that had normal levels were 11 (36.67%) samples and 19 (63.33%) samples with abnormal C-Reactive Protein levels. Spearman's Rank statistical test results obtained a value of p = 0.000 < 0.05, indicating a correlation between the number of Blue Plasma Lymphocytes and C–Reactive  Protein levels in Dengue Hemorrhagic Fever patients. Conclusion: The more Blue Plasma Lymphocytes, the higher C–Reactive Protein levels in Dengue Hemorrhagic Fever.Keywords: blue plasma lymphocytes, C–reactive protein, dengue hemorrhagic feve
Insidensi Bayi Berat Lahir Rendah pada Spektrum Plasenta Akreta di Rumah Sakit Dr Hasan Sadikin Bandung
Full text linkLow birth weight (LBW) babies are closely related to infant morbidity, stunted growth and cognitive development, and chronic diseases. Placenta accreta spectrum (PAS) is a condition that complicates pregnancy and is closely related to low birth weight. Objectives: To determined the incidence of LBW in mothers with SPA at the hospital Dr. Hasan Sadikin Bandung. Methods: A descriptive observational study involving 71 cases of SPA in hospitals Dr. Hasan Sadikin Bandung, period 2016-2020, which has met the inclusion and exclusion criteria. SPA cases were divided into three groups: placenta accreta, increta, and percreta. In each SPA group, the incidence of LBW was evaluated. Results: 46.5% (33/71 cases of PAS) had low birth weight, while 53.5% (38/71 cases of PAS) had normal birth weight babies. The placenta accreta and percreta groups were dominated by normal birth weight infants [(18/31 cases), (5/9 cases)], while the placenta increta group was dominated by low birth weight infants (16/31 cases). The LBW category is divided into Extremely Low Birth Weight (ELBW), Very Low Birth Weight (VLBW), and LBW. In placenta accreta, there were 2 ELBW and VLBW infants, and 9 LBW infants. In the placenta increta, there are 3 ELBW and VLBW, and 10 LBW. In the placenta percreta, there were 1 ELBW and 3 LBW, while VLBW was not found in the placenta percreta. Conclusion: The incidence of LBW is found in almost half the population of SPA cases in hospitals. DR. Hasan Sadikin in the 2016-2020 period.Keywords:  low birth weight, placenta accreta spectru
Hubungan Kejadian Hipertensi dengan Kualitas Hidup Penduduk Lanjut Usia di Wilayah Kerja Puskesmas Rijali Desa Batu Merah Kota Ambon Maluku
Full text linkHypertension is a degenerative disease that is often encountered in older people. Health status, such as hypertension, can interfere with the quality of life of the elderly. Objective: To determined the relationship between the incidence of hypertension and the quality of life of the elderly in the working area of the Puskesmas Rijali, Batu Merah Village, Ambon City, in 2022. Methods: This study was an observational analytic study with a cross-sectional design and used a consecutive sampling technique in sampling. Results: This study showed that from 76 samples, as many as 40 people (52.6%) suffered from hypertension and 36 people (47.4%) did not. Eight people (10.5%) had poor quality of life and 68 people (89.5%) had a good quality of life. The bivariate analysis results using Chi-square showed a p-value = 0.715 (p > 0,05). Conclusion: It can be said that there is no significant relationship between the incidence of hypertension and the quality of life of the elderly. Further research is needed regarding other factors that affect the quality of life of the elderly such as subject characteristics, medication adherence, and other chronic diseases, which according to several studies, have significance in determining the quality of life.Keywords: elderly, Â hypertension, quality of lif
Hubungan antara Rasio Neutrofil Terhadap Limfosit Preterapi dengan Angka Harapan Hidup Pasien Karsinoma Nasofaring di RSUD Abdoel Wahab Sjahranie Tahun 2018
Full text linkNasopharyngeal carcinoma is a malignancy that originates from the epithelial tissues lining the nasopharynx and is considered one of the most common malignant cancers which cause mortality in Indonesia. Neutrophils and lymphocytes are the first lines to provide body immunity against foreign substances. Neutrophil-to-Lymphocyte Ratio (NLR) is a prognostic factor in various malignancies. Objective: To investigated the correlation between pre-therapy Neutrophil-to-Lymphocyte Ratio (NLR) and survival rate among patients with nasopharyngeal carcinoma at Abdoel Wahab Sjahranie Regional Public Hospital in 2018. Methods: The Neutrophil-to-Lymphocyte Ratio (NLR) data were obtained from outpatient medical records at Abdoel Wahab Sjahranie Regional Public Hospital in 2018. In addition, the data on mortality status were collected based on the information after directly contacting the patients. A purposive sampling technique was used to collect the data. Thirty-three data of patient medical records were obtained and analyzed using Kaplan-Meier survival analysis with a significant p-value of <0.05. Results: The analysis result showed p-value of 0.495. Conclusion: There is no correlation between pre-therapy Neutrophil-to-Lymphocyte Ratio (NLR) and survival rate among patients with nasopharyngeal carcinoma.Keywords: Â nasopharyngeal carcinoma, neutrophil-to-lymphocyte ratio, survival rat
Hubungan Kadar Enzim Transaminase Pasien COVID-19 dengan Derajat Keparahan Penyakit di RSUP Dr. M. Djamil Padang
Full text linkLiver injury can be caused by coronavirus disease 2019 (COVID-19), characterized by increased levels of transaminase enzymes (aspartate aminotransferase/AST and alanine aminotransferase/ALT). Objective: To determined the correlation between transaminase enzyme levels and the severity of COVID-19 in Dr. M. Djamil Central Public Hospital, Padang. Methods: This was an observational analytic study with a cross-sectional design. Data were obtained randomly from medical records of confirmed COVID-19 patients hospitalized in Dr. M. Djamil Hospital from June to August 2021, with moderate, severe, and critical severity based on Indonesian Ministry of Health criteria. Data were analyzed using the Chi-square test to examine the distribution and correlation between variables and a simple logistic regression test to assess the level of risk between variables. Results: 57,80% had abnormal AST, and 44,95% had abnormal ALT. The median AST was highest in the critical group, while the median ALT was highest in the severe group. The distribution of sex and age group were significantly different based on AST and ALT levels, and the distribution of patients with coronary heart disease was significantly different based on ALT levels. Transaminase enzyme levels had a significant correlation with the severity of COVID-19 (p-value = 0,00). Patients with critical degrees had the highest risk for abnormal AST and severe degrees had the highest risk for abnormal ALT. Conclusion: Transaminase enzymes have a significant correlation with the severity of COVID-19.Keywords: Â COVID-19, liver injury, transaminases, disease severit
Pengaruh Positifitas Leukosit Esterase dan Nitrit Urine Terhadap Nilai Neutrophil Lymphocyte Ratio (NLR) pada Pasien Infeksi Saluran Kemih
Full text linkUrinary tract infection (UTI) characterized by positivity of leukocyte esterase and nitrite can affect the Neutrophil Lymphocyte Ratio (NLR) value as a reflection of the degree of infection and inflammation by pathogenic microorganisms. Objective: To analyzed the effect of positivity leukocyte esterase and nitrite urine on NLR values in UTI patients. Methods: This study used an observational analytic method with a cross-sectional approach. UTI patients will be subjected to urinalysis and complete blood cell examination. The data obtained will be subjected to the Pearson correlation and linear regression tests. Results: This study used 36 samples of UTI patients with an abnormal number of positive leukocyte esterase samples in 36 samples (100%), positive urine nitrite in 20 samples (55,6%), and abnormal NLR values >3,5 are 27 samples (75%) with a mean of 10,21. Conclusion: There is a significant influence and relationship between the positivity of leukocyte esterase and urine nitrite on NLR value in UTI patients with a simultaneous value of 45,1% and p 0,000.Keywords: Â UTI, leukocyte esterase, urine nitric, NL