Jurnal Kesehatan Andalas
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Korelasi Kadar Protein C-Reaktif dengan Rasio Kolesterol Total / HDL pada Penyandang Obes di RSUP Dr M Djamil Padang
C-reactive protein is an acute-phase protein produced by the liver in response to inflammation. Dyslipidemia can trigger the inflammatory reaction in the blood vessels, causing atherosclerosis. The ratio of total cholesterol/High Density Lipoprotein (HDL) is considered as one of the sensitive predictor lipid ratio for the cardiovascular disease risk factor. Objectives: To determined the correlation of C reactive protein between cholesterol levels with total cholesterol/HDL ratio in obese people. Methods: This study was an analytical study with a cross-sectional design of 59 people who met the inclusion and exclusion criteria at the RSUP Dr. M. Djamil Padang from January to September 2019. Research subjects consisted of first degree obesity (25.0 ≤IMT <30.0 kg/m2) and second degree (≥30.0 kg/m2). C reactive protein levels were measured as high-sensitivity C-reactive protein. Total cholesterol and HDL levels were measured using automated clinical chemicals with the enzymatic colorimetric method. Data were analyzed by Pearson, significant if p <0.05. Results: The study subjects were 59 people (17 men and 22 women) with an average age was 35 (8.04) years. CRP levels in stage II obesity were slightly higher than grade I, with a mean difference between groups of 0.26 mg/L (95% CI: -1.80-1.2; p=0.74). The average ratio of total cholesterol/HDL levels in the obese group I and II was 5.13 and 4.80 (p=0.93). The correlation showed a very weak positive (r=0.12) and was statistically not significant (p=0.35). The results of the subanalysis showed relatively similar patterns between the first-degree obesity population (r=0.10; p=0.58) and second-degree (r=0.16; p=0.41). Conclusion: There is no significant correlation between protein C-reactive and total cholesterol/HDL ratio.Keywords: Obesity, C-Reactive Protein, total cholesterol/HDL rati
Efek Suplementasi Selenium terhadap Marker Darah Pasca Cedera Kontusio
Selenium is a trace element that has antioxidant properties and is a component of selenoproteins. In certain circumstances, such as injury, selenium supplementation is required to regulate the inflammatory response. Contusion injury increases the inflammatory response to a muscle or tissue that begins with vasodilation, increases blood flow, increases vascular permeability, and leads to edema formation at the site of injury. Objectives: To determine the effect of selenium supplementation on changes in blood markers in rats treated with contusion injury. Methods: Experimental design, using experimental male rats (Rattus norwegius), eight weeks old, weighing 200-220 grams, divided into three groups, namely: The Control group, the contusion group, the contusion + Selenium group. Selenium supplementation was given orally on days 1-3 after injury at a dose of 0.0153 mg into 2% PGA. Examination of markers such as White Blood cells (WBC), lymphocytes, monocytes, and neutrophils was carried out on day three after treatment. Results: This study found that the administration of post-muscular selenium supplementation based on examination of blood markers such as WBC, Lymphocytes, Monocytes was higher in the contusion group and lower in the selenium group. Neutrophils were higher in the contusion and selenium groups. This was not significantly different from the control group. The result of blood marker examination tended to change, but it was not statistically significant. Conclusion: Selenium supplementation in post-contusive injury mice did not provide significant changes in blood markers such as WBC, lymphocytes, monocytes, and neutrophils.Keywords: Â antioxidant, blood marker, contusion, seleniu
Sikap Ibu Terhadap Pemberian Imunisasi Measles Rubella Secara Tepat Waktu Selama Pandemi Covid-19
The timeliness of Measles-Rubella (MR) immunization is still low among other immunization services for infants, including at the Tempuran Health Center, Magelang Regency. Attitude is something that influences a person's actions. Objectives: To analyzed the mother's attitude towards MR immunization services on time during the covid-19 pandemic in the working area of the Tempuran Health Center, Magelang Regency. Methods: It was quantitative research with a cross-sectional approach. The research population was mothers who have babies aged 9-12 months with a sample of 100 mothers using cluster sampling technique in each village. The research instrument was a questionnaire. The data were analyzed univariately and bivariate with the Chi-square test. Results: The timeliness of MR immunization was still low. 74% of mothers were not punctual in immunizing MR to their children even though most mothers had a good attitude (65%). The Chi-square test showed a relationship between the mother's attitude and timeliness of MR immunization (p=0.004). Conclusion: The mother's attitude was not optimal because there were various problems with the mother's attitude, so it is hoped that the mother will increase knowledge, share experiences with peer groups, and if unable to attend, ask for family assistance, while health center is expected to carry out promotions, education about measles-rubella immunization and also coordinate with health office regarding vaccine stockKeywords: Â immunization, measles-rubella, timelines
Hubungan Kecemasan pada Visit Pre-Anestesi dengan Tekanan Darah sebelum Tindakan Anestesi di Rumah Sakit Universitas Sumatera Utara
Preoperative anxiety is frequently correlated with anesthesia procedures, resulting in the anesthesiologist being the most suitable person to decrease the patient's anxiety through effective doctor–patient communication during pre–anesthesia visits. During anxiety, one of the body responses is the release of epinephrine to the blood vessel resulting in increased blood pressure. Objectives: To knew the correlation between pre-anesthesia visit anxiety and blood pressure before anesthesia procedure. Methods: This study used a cross-sectional design that was conducted at Universitas Sumatera Utara General Hospital from September until October 2019. The sample was collected by consecutive sampling techniques, which meet inclusion and exclusion criteria. This study used primary data then was analyzed using Fisher’s Exact Test. Results: From 67 patients going through elective surgery, there are 41 patients (61,2%) with mild anxiety, 17 patients (25,4%) with moderate anxiety, and nine people (13,4%) with severe anxiety. There is no significant correlation (p>0,05) between anxiety with sex, types of anesthesia, PS ASA and heart rate. There is a significant correlation (p<0,05) between anxiety with blood pressure and types of surgery. Conclusion: There is a correlation between anxiety during the pre-anesthesia visit with blood pressure before anesthesia procedures.Keywords:  anesthesia, anxiety, blood pressure, pre-anesthesia visi
Hubungan Derajat Nyeri pada Brief Pain Inventory dengan Stadium Kanker Payudara
Breast cancer is a condition in which cells have undergone normal repairs, resulting in abnormal growth. In Indonesia, patients with metastatic cancer (stage IV) tend to have a lot of complaints and complications due to cancer they experience. Pain is the main complaint that is often complained of. Objectives: To determined the relationship between the degree of pain in BPI (Brief Pain Inventory) and the stage of breast cancer. Methods: Â Research conducted is analytic with cross-sectional design. The study sample was patients diagnosed with breast cancer in RSUP HAM who had met the inclusion and exclusion criteria based on the total sampling method. Research data are primary data taken using interview techniques. The research instrument was the BPI questionnaire. BPI is a measure of pain experience that measures the severity of pain and disruption of daily functioning due to the pain experienced by patients. Measured using a ratio scale where the score of 0 is the lowest and the ten highest scores have the worst pain intensity. Results: The analysis of the Chi-square test showed a significant relationship between the degree of pain and the stage of breast cancer in RSUP HAM with a p= 0,01 (p<0,05. Conclusion: There is a relationship between the degree of pain and the stage of breast cancer.Keywords: Â BPI, breast cancer, pain, stag
Pengaruh Art Therapy terhadap Kualitas Hidup Anak Kanker yang Menjalani Kemoterapi
Continuous chemotherapy causes side effects in children, one of which affects the quality of life of children. The quality of life of children with cancer can be improved by providing complementary and alternative therapies, one of which is art therapy. Objective: To determine art therapy's effect on the quality of life of cancer children undergoing chemotherapy. Methods: The design of this study was a quasi-experimental one-group pre-test post-test on 30 children with cancer who underwent chemotherapy. The art therapy in this study was coloring activities. Quality of life assessed using PedsQoL instruments (Pediatric‘s Quality of Life) Generic 4.0. Data analysis used the Mann-Whitney test. Results: The average age of children with cancer was ten, and more than half (53.3%) were male. Most of them were diagnosed with Acute Leukemia Limfoblastic and more than half (73.3%) were diagnosed more than six months. There was a difference in the quality of life of children with cancer before and after being given art therapy with a p-value = 0.000 (<0.05). Art therapy affected the quality of life of cancer children undergoing chemotherapy with a p-value of 0.000 (<0.05). Conclusion: Art therapy can improve the quality of life of cancer children undergoing chemotherapy. Keywords:  art therapy, chemotherapy, children with cancer, quality of lif
Hubungan antara Kadar HbA1c dan Derajat Retinopati Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Mata Cicendo Bandung
Diabetic retinopathy is the common complication of T2DM, which leads to vision loss. The severity of retinopathy can be affected by HbA1c levels. Controlling the glycemic such as HbA1c, may prevent the severity of diabetic retinopathy. Objective: To identified the association between HbA1c levels and severity of retinopathy in Type 2 DM patients at Cicendo Eye Hospital, Bandung. Methods: This research was an analytic observational study and cross-sectional approach. Samples were taken using purposive sampling and consisted of 70 people. The secondary data were from the outpatient's medical records at the Cicendo Eye Hospital in Bandung for the period September-October 2022. The Chi-square test was used for data analysis. Results: According to HbA1c levels, the uncontrolled HbA1C levels were found in 52 patients (74,3%) and the controlled were found in 18 patients (25,7%). Most of them were diagnosed with PDR were found 62% and the rest of it were diagnosed with NPDR. A significant association is found between HbA1c levels and the degree of diabetic retinopathy with p-value = 0.018 (p <0.05). Conclusion: HbA1c levels in Type 2 Diabetes Mellitus patients have a significant association with the severity of diabetic retinopathy, which can be used as a parameter for controlling diabetes complications, particularly retinopathy.Keywords: diabetic retinopathy, T2DM, HbA1c, glycemic contro
Pengaruh Mobilization With Movement terhadap Nyeri dan Lingkup Gerak Sendi Penderita Osteoarthritis Lutut di Rumah Sakit Islam Klaten
Osteoarthritis (OA) is characterized by pain that causes a decrease in knee joint range of motion, affecting a person's gait change and quality of life. Manipulation with Movement (MWM) is the most commonly used manual therapy technique in musculoskeletal disorders, especially in arthritis, to increase the range of movement (ROM). The MWM technique with a sliding direction aims to minimize pain and increase ROM in patients with knee OA. Objective: To determined the effect of MWM on pain and range of movement (ROM) in knee joint OA patients. Methods: This research was an experimental study with a quasi-experimental approach without a control group design. The research group consisted of 18 female patients who used the MWM technique two times a week for four weeks. The pain and ROM were measured by NRS and goniometer, respectively. Results: There were significant effects of MWM to reduce pain and increase ROM of knee joint (p<0.05). The average ROM of knee flexion and knee extension were improved by 12.2 and 1.7 degrees, respectively. The average pain was decreased by 2.4 as well after being treated by MWM for four weeks. Conclusion: MWM exercises were trained for four weeks to reduce pain and increase knee range of motion in flexion and extension in OA patients. MWM is recommended as an approach exercise for patients with knee OA to be involved in a rehabilitation program.Keywords: mobilization with movement, pain, range of joint movement, knee osteoarthriti
Profil Penderita Ablasio Retina Eksudatif di Klinik Mata SMEC Tahun 2019-2022
Retinal detachment is a critical ocular condition arising from separating two retina layers, leading to an abrupt decline in visual acuity. Exudative retinal detachment occurs due to fluid accumulation from the inflammatory reaction. Objective: To ascertain the demographic characteristics of individuals diagnosed with retinal detachment at SMEC Eye Clinic in Samarinda from 2019 to 2022. Methods: This study was a cross-sectional descriptive study that utilized data from the available population. The sample comprises seven medical records of patients with exudative retinal detachment at SMEC Eye Clinic in Samarinda between 2019 and 2022. Results: The age range observed was six patients (85.7%) between the ages of 15-65 years and one patient (14.3%) > 65. The mean age of patients was 39,4 years. Among the patients, 6 (85.7%) female and 1 (14.3%) male. Unilateral eye involvement was observed in 6 patients (85.7%), while bilateral involvement was observed in 1 (14.3%). The most commonly observed accompanying eye disease was choroidal disorder. In contrast, the most commonly observed non-eye comorbidity was diabetes mellitus. Conclusion: Most exudative retinal detachment cases observed at SMEC Eye Clinic between 2019 and 2022 were concentrated within the age bracket of 15 to 65 years, with a higher proportion of female patients. The condition was predominantly unilateral, and the presence of comorbidities such as choroidal disorder and diabetes mellitus was also noted.Keywords: Â affected eye side, comorbidities, exudative retinal detachment, risk factor
Gambaran Radiografi Toraks Sebagai Prediktor Outcome Pasien COVID-19
COVID-19 (coronavirus disease 2019) is a pulmonary infection disease caused by SARS-CoV-2. Chest radiographic examination of COVID-19 cases performed to make a diagnosis and monitor therapy. Objective: To   evaluated the results of chest radiography examination in COVID-19 cases as a predictor of patient outcome after treatment at the Sultan Agung Islamic Hospital in Semarang. Methods: This research was an observational analytic study with a retrospective design using medical record data from January until December 2021. The results of chest radiographs were analyzed using the Brixia Score system with a maximum score of 18. Outcomes of COVID-19 patients were described as recovered patients or died. Data analysis uses the ROC curve to determine the cut-off point. Results: This study showed that out of 47 patients (43±14 years old), 39 patients (81%) recovered and nine patients died (19%). The levels of leukocytes, D-dimer, Neutrophil-lymphocyte ratio (NLR), and Brixia scores were significantly higher in dead patients (p<0.05). Sensitivity and specificity values predictor of leukocyte count (83%, 61%), D-dimer (83%, 84%), NLR (83%, 82%), and Brixia score (83%, 79%), respectively. Conclusion: Increased levels of leukocytes, D-dimer, NLR, and Brixia Score can be used as a predictor of patient mortality after hospitalization.Keywords: Brixia score, COVID-19, thoracic radiograp