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Studies on the role of cholesterol in the pathogenesis of prion diseases: I. Correlation between cell susceptibility to prion infection/replication and altered cellular cholesterol distribution
The aim of the research project was to investigate whether cell susceptibility to prion infection/replication was somehow related to alterations in the intracellular cholesterol homeostasis, and in particular whether unbalanced FC vs. CE pools could be found in prion infected/prion susceptible cells with respect to cell conditions of no infection or genetic resistance
The adoption of a Comprehensive Income Statement in Italy: has the time of a new disclosure come?
Nowadays financial and economic performances achieved in the period and their projections in the future are of particular relevance to all users of financial statements. Although they utilize and search for different financial information, all of them require comprehensive, appropriate, timeliness, relevance and reliable information. This study examines the lack of information provided by current Italian and European forms of Income Statement as fundamental instrument for financial and economic disclosure and how this information could not be useful to users in making their economic decisions, especially now that IFRSs will be adopted for preparing separate and only financial statements of Italian non-financial listed companies. If until now, Italian and European GAAP have preferred accounting principles to determine distributable incomes, IFRSs’ adoption will move our care in determining comprehensive performances and companies’ assets and liabilities expressed at current value. In such cases a new form of Income Statement is required. In this study a proposal of Comprehensive Income Statement is given. It considers the different Italian concepts of realization, prudence and restrictions on fair value gains distributability, as well as the new IFRSs’ accounting measurements required by their adoption. Such Statement fosters the quality of information to investors for their economic decision-making, taking into account the law requirements concerning capital maintenance
Aspetti e problemi dell'appartenenza dei soggetti umani all'impresa
I soggetti umani disponendo di creatività, vitalità e sapere forniscono le risposte più adatte per operare in un mercato caratterizzato da un’elevata complessità sistemica e da una forte competitività. Affinché questa condizione si verifichi è necessario che si diffonda una cultura organizzativa orientata all’esaltazione, alla valorizzazione, alla responsabilizzazione e alla motivazione dei soggetti umani.
L’obiettivo della ricerca è pertanto, quello di richiamare, per il tramite dell’adozione di un approccio multidisciplinare, dove le teorie economiche si integrano e si fondono con le teorie psicologiche, l’attenzione sui fattori che incidono sulla condizione di appartenenza dei soggetti umani. In particolare, si fa riferimento a quelli che creano condizioni di coesione, di condivisione e di supporto, in modo da ridurre in maniera drastica gli atteggiamenti passivi e non collaborativi e favorire l’identificazione degli obiettivi personali con gli obiettivi di sistema. I risultati conseguiti, devono necessariamente considerarsi di prima approssimazione, poiché lo studio di fenomeni complessi quali gli interessi, i bisogni più profondi di ogni soggetto umano operante nell’impresa, gli elementi che influiscono sul loro comportamento e sull’attribuzione del valore di ciascun individuo all’entità nella quale opera, non conduce mai ad una conoscenza oggettiva e completa a causa della molteplicità dei fattori che concorrono a determinarli, alcuni intrinsechi negli stessi soggetti umani
Analisi della vegetazione del distretto minerario di Montevecchio (Sardegna sud-occidentale)
Montevecchio (SW-Sardinia) are presented. The statistic analysis of the relevés let to recognize 14 plant communities. The hygrophilous communities
have been ascribed to the class Phragmito-Magnocaricetea, the hemicryptophytic mesohygrophilous ones to Juncetea maritimi, the therophytic to
Tuberarietea guttatae and the hemicryptophytic mesoxerophilous to Lygeo-Stipetea.
The most interesting vegetation types turned out to be the chamaephytic and nanophanerophytic ones, both kinds are belonging to sardo-corsican
endemic alliances: Ptilostemono casabonae-Euphorbion cupanii and Teucrion mari, respectively. The first alliance comprises pebble vegetation with
distinctive ecological preferences, as they are able to colonize substrata polluted by heavy metal, with low pH values. Within this alliance, 4 new
associations have been recognized: Scrophularietum bicoloris, Dactylo hispanicae-Helichrysetum tyrrhenici, Mercurialido corsicae-Euphorbietum
cupanii and Dauco maritimi-Dittrichietum viscosae, the latter with two subassociations (typicum and rumicetosum glaucescentis). As to the Teucrion
mari, 1 new association and 1 subassociation have been described (Helichryso tyrrhenici-Genistetum sulcitanae and Stachydi glutinosae-Genistetum
corsicae euphorbietosum cupanii), found on aged mining dumps, where the long abandonment made possible the beginning of the pedogenetic
processes.
The present study let to reconstruct the vegetation dynamics, that in the mining areas are clearly differing from the surrounding territory. It was
possible to identify two special series, strictly related to these habitats and verging to the establishment of plant communities pertaining to the
climatophilous series: the first is developing on coarse, hard-sloping debris, with very low water retention; the second is developing on fine-grained
and coherent materials, found on flattened or gently-sloping sites, with high edaphic humidity. In wetlands, it was also possible to identify an
edaphohygrophilous series and a geoseries of endoreic water bodies, not exclusive of the mining habitats
Conservazione ex situ e in situ della biodiversità vegetale dell'Area Marina Protetta di Capo Carbonara (Sardegna sud-orientale)
The first results of the project "Plant Biodiversity Conservation in the Protected Marine Area of Capo Carbonara (PMA)" are illustrated. This
initiative, promoted by the CCB and the Municipality of Villasimius (CA), was funded for three-year period (2005/07) by the Ministry of the
Environment and Territory protection. The project provides the study, monitoring and conservation of the coastal habitat, principally on all the Sites
of Communitary Importance (pSIC) of the Villasimius Municipality territory, in order to plan a harmonic development between coastal and sea areas
unifying the environmental protection secured by the PMA with that relatives to the Natura 2000 network.
During the first year there were started ecological, floristic-sociological and chorological studies, in order to value the actual state of conservation and
have a possibility to propose adequate measures for a sustainable management.
In order to guarantee the effective plant biodiversity conservation, the following ex situ actions have been made: collection, study and conservation
for a long time of the seed of selected species in the structures of the Sardinian Seed Bank (BG-SAR), according to international procedures and
protocols. At the end of the first year the seed harvest was completed relatively to all the species with a greater risk of extinction.
The project provides also actions directed to sensitize the population, local and non, on the thematics of the conservation and the sustainable development
of the territory
La flora del Monte Arcuentu (Sardegna sud occidentale)
The results of an anaytical survey of the flora of Monte Arcuentu, a volcanic
massif in SW Sardinia, are reported. The survey resulted in 556 recorded taxa, belonging to 335 genus, 84 families and 39
orders. The most represented Phylum is Magnoliophyta (539 taxa), of which the Eudicots represent the richest systematic
group, with 22 orders, 54 families and 405 species. The most represented orders are: Asterales (74 taxa), Lamiales (59), Fabales
(53) and Caryophyllales (30).
Most of the recored taxa were belonging to Asteraceae (71), followed by Fabaceae (52) and Poaceae (51). Most frequent genera
are: Trifolium (11), Euphorbia (9), Allium, Geranium, Juncus, Medicago, Ophrys, Orobanche (7).
The biological spectrum highlights the remarkable Mediterranean connotation of the studied district, being the therophytes
(40.8%), followed by hemicriptophytes (27.0%) and geophytes (14.7%) being the most frequent growth forms. Indeed, the
chorologic spectrum is dominated by the Mediterranean chorotype (48.4%), whose main partitions are: steno-Mediterranean
(22.8%), endemic (9.7%) and W-Medit. (9.3%). Taxa with a broader distribution range, but centred in the Mediterranean
basin, represent the 26.6%. The endemic taxa were 54 , among which Asteraceae (8) and Fabaceae (5) were the most
represented families. The chorologic spectrum of the endemic units is dominated by Sardo-Corsican taxa (20), followed by
Italo-Tyrrhenian ones (14).
The analysis of rarity, according to the categories of Rabinowitz, highlighted the fact that the largest group (231) consists of
WBL (i.e. species diffused over the territory, with a wide ecology and a large local population, in some places dominant),
while the smallest one (5) is formed by the NBL (i.e. species with a limited spread over the territory, a wide ecology and a
large local population, at times dominant).
The taxa protected by international regulations are all the recorded orchids (19) and Cyclamen repandum subsp. repandum,
included in the attached II of CITES, Brassica insularis in the Berne Convention, 2 in the Habitat Directive (Brassica insularis
and Ruscus aculeatus), plus 3 (Soleirolia soleirolii, Hyoseris taurina and Genista morisii) cited in the IUCN- red lists
Uno specchio frammentario. La soggettività umana in H. G. Gadamer tra determinazione storica e responsabilità al singolare
The research aims to analyse the terms in which Hans Georg Gadamer’s philosophical hermeneutics considered the idea of human subjectivity. The way that has been developed at first took up again the fundamental gadamerian text, Truth and Method, finding in it the lines of an overcoming the subjectivity and of its heterodetermination by the historical and sociocultural context in the first place. The principal and more characteristic concepts of the gadamerian thought (play, prejudice, the consciousness of historical determination, the history of effects, and so on), have been treated again, just according to the peculiar key of interpretation of the subjectivity. Special attention has been given to the language, since through it an accurate diachronic analysis was possible about this theme in the author’s writing. Subsequently to this founding part we have outlined the subject of a social reason, understood as a collective concrete matter which inserts itself in the social dialogue and the culture and then becomes a heritage of contents and ideas that are a background for every individual reflection and action. In a third section the presence of some elements in Gadamer’s hermeneutics has been detected, especially through the examination of a series of short essays written in his “second philosophical youth”, which can be traced back to a conception of liberty of the subjectivity of man, glimmers that express themselves mainly in the moment of decision, with its solitude, and are synthesized in the extreme formula of a responsibility which, though raised on a base of communitarian ethos, continues to be an irrevocable principle of singularity
Lagrangian acceleration measurements via PTVA (Particle Tracking Velocimetry and Accelerometry) on a turbulent-like flow
Quasi-two-dimensional turbulence (Q2D) has both a practical and theoretical relevance. Following the topological approach, turbulent-like flows have the aim to model and study some of the aspects of turbulence. With this target, in the laboratory of the Imperial College London, Q2D electromagnetically-controlled multiple-scale flows are experimentally studied. To study those flows, an accurate Lagrangian technique to measure acceleration is needed: a novel technique, Particle Tracking Velocimetry and Accelerometry (PTVA), based on Image Analysis techniques, has been designed, developed and validated. PTVA is a self-adaptive methods which relies on a number of positions to approximate the trajectories that adapts to the topology and acceleration of the flow and grants much more precise measurements compared to previous methods. PTVA has allowed to experimentally measure all the Navier-Stokes equation’s terms over the entire investigation field, to classify zero acceleration points, to extract the map of power input and output along with the one of the divergence of acceleration (stirring intensity), measured for the first time, obtaining the tools to work on mixing efficiency. The pdf of the acceleration components has turned out to be very similar to the one usually measured in real turbulence: as this pdf has been often considered as the signature of turbulence, this result makes the question of which characteristics of turbulence generate which features arise
Flora e paesaggio vegetale del Sarrabus-Gerrei (Sardegna sud orientale)
Le ricerche hanno riguardato lo studio della flora e del paesaggio vegetale del Sarrabus-Gerrei (Sardegna sud orientale), un’area che si estende per 160000 ettari nella provincia di Cagliari. Il territorio è caratterizzato in prevalenza da rocce intrusive granitiche del Carbonifero e metamorfiche devoniche e siluriane. Dal punto di vista bioclimatico i territori indagati sono compresi in termotipi variabili dal termomediterraneo inferiore al mesomediterraneo superiore e ombrotipi che vanno dal secco inferiore all’umido inferiore. Le ricerche sulla flora hanno permesso di censire 1447 unità tassonomiche comprese in 125 famiglie e 565 generi. Le endemiche sono risultate costituite da 112 taxa compresi in 68 generi e 30 famiglie. Relativamente alle misure di tutela e protezione 60 taxa risultano inseriti nelle Liste Rosse IUCN, 4 nella direttiva Comunitaria Habitat 92/43 e 17 nella CITES. Il paesaggio vegetale risultato costituito da numerose fitocenosi appartenenti alle seguenti classi: Quercetea ilicis, Querco-Fagetea, Nerio-Tamaricetea, Salicetea purpureae, Cisto-Lavanduletea, Rosmarinetea officinalis, Lemnetea, Potametea, Phragmito-Magnocaricetea, Ammophiletea, Helichryso stoechadis-Crucianelletea maritimae, Cakiletea maritimae, Ruppietea maritimae, Posidonietea, Crithmo-Limonietea, Juncetea maritimi, Saginetea maritimae, Salicornietea fruticosae, Arthrocnemetea, Thero-Suadetea, Asplenietea tricomanis, Paritarietea, Anondo-Polypodietea, Scrophulario-Helichrysetea italici, Helianthemetea, Artemisietea vulgaris, Polygono-Poetea annue, Stellarietea mediae, Thero-Brachypodietea, Poetea bulbosae
Studio di tecniche di gestione e di processi di assegnazione automatica nel monitoraggio di fattori di inquinamento acustico a mezzo dei Sistemi Informativi Territoriali
The purpose of this work is to analyze a model for the management and development of categories of environmental data, using some decision support systems such as the Geographic Information Systems (GIS), applied to the fuzzy analysis. As a "case study", the research was focused on the analysis of noise data and on the geographical context of the Province of Cagliari. During the research project, all the geographical themes and the socio-economic and noise data, once stored, processed and structured, were put into many databases, related to each other by logical, geographical and topological links and rules. All the databases, dialoguing among themselves and with the GIS, create the Noise Decision Support System: a model that improves the analysis effectiveness, increasing the number of the verifiable alternatives and providing assistance to the “acoustics landscape planning”. One of the results of the work was to create a sort of "provincial acoustics zoning", identifying where some possible "critical areas" are located in the region