STOMATOGNATIC- Jurnal Kedokteran Gigi
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Efektivitas Gel Esktrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) terhadap Penyembuhan Ulser Pada Tikus Wistar
Ulcer is a lesion that is often found in the oral cavity that causes discomfort, pain, difficulty speaking and difficulty eating. Nowdays, herbal ingredients are widely used as alternative medicine choice besides drugs on the market. Pandan leaf contains flavonoids, alkaloids, saponins, and polyphenols which have antiinflammatory, antibacterial, and antioxidant abilities, allowing faster healing of ulcers. Purpose of this study was to determine the effect of pandanus leaf extract gel on healing ulcers and determine the most effective concentration in healing ulcers. This study used 25 Wistar rats divided into 5 groups, which were applied CMC-Na gel, aloclair gel, 25%, 50% dan 75% pandan wangi leaf extract gel. Each rat was made ulcer by heating the stopper amalgam on the bunsen fire for 30 seconds, then touching to the left buccal mucosa for 1 second, and waiting for 2x24 hours to form an ulcer. Giving the gel every morning and evening and measure the diameter of ulcers every day. This study showed healing time and decrease ulcer diameter pandanus leaf extract gel faster than negative control. The average recovery day was negative control for 9.8 days, positive control for 8 days, pandanus leaf extract gel concentration 25% for 8.6 days, concentration 50% for 8 days, and concentration 75% for 6.8 days. Pandan leaf extract gel accelerated ulcer healing and 75% concentration is the most effective
Hubungan Ekspresi Osteocalcin dan Interleukin-1β dengan Status Inflamasi Periodontal
Periodontitis is inflammation of the periodontal tissue that can cause progressive damage to the periodontal ligament and alveolar bone. Clinical examination to determine the degree of damage to the alveolar bone using a periodontal probe instrument or probing. Cellular activity in the gingival crevicular fluid is thought to be a biomarker to determine the inflammatory status of the periodontal tissue. Cellular immune responses suggest the role of cytokines in the pathogenesis of gingivitis and periodontitis. The cytokines observed in this study were the protein Osteocalcin and Interleukin-1β (IL-1β) in the gingival crevicular fluid (GCF). In this study, 67 patients were examined for the condition of their periodontal tissues including the severity of gingivitis and periodontal probing. The gingivitis group was divided into 4 groups, namely normal, mild, moderate, and severe. Meanwhile, for probing samples were grouped based on probing into 3 groups. Group I (0-3 mm), group II (3.1-5 mm) and group III (> 5 mm). GCF was obtained using paper points that were left in the gingival sulcus for 30 seconds. Then paper points are put into cryovial tubes which are sent to the laboratory for ELISA test. The observed data on the expression of Osteocalcin and IL-1β were then performed statistical tests. Osteocalcin and IL-1β expression showed a significant difference with the severity of gingivitis cases. In the other hand, it did not show a significant difference with difference of periodontal pocket depth. Osteocalcin and IL-1β expression associated with the severity of gingivitis cases
Efektivitas Gel Ekstrak Biji Kopi Robusta (Coffea canephora) terhadap Peningkatan Jumlah Fibroblas pada Penyembuhan Luka Pasca Gingivektomi
Gingivectomy is a surgical procedure aimed at eliminating pseudo pocket in gingival hyperplasia, and also to obtain a good gingival margin aesthetic. The process of wound healing after gingivectomy takes a long time. Fibroblasts are cells that takes an important role in the process of wound healing. One alternative treatment giving medication by applying Robusta coffee bean extract gel which acts as an anti-inflammatory and antioxidant in the wound healing process. The objective was to determine the potential and optimal concentration of Robusta coffee bean extract gel to increase the number of fibroblast cells in post-gingivectomy wound healing phase. This study used 32 male wistar rats were divided into 4 groups. All male wistar rats were treated with gingivectomy in the left mandibular first molar tooth area. The first group as a negative control did not apply any drug, the second group applied 40% robusta coffee extract gel, the third group applied 50% robusta coffee extract gel, and the fourth group 60% robusta coffee extract gel was applied. On the 3rd and 7th day, the experimental animals in all groups were decapitated to do a histological examination of fibroblasts in post-gingivectomy wounds phase. The result showed that applied robusta coffee extract gel present higher number of fibroblasts than the negative control group. The group of 40% dan 50% shows a significant difference of the number of fibroblasts on the 3rd and 7th day. The conclusion was robusta coffee bean extract (Coffea canephora) potential to increase the number of fibroblasts in wound healing phase after gingivectomy, with an effectivity concentration of 40% and 50%
Arsitektur dan Komposisi Mineral Atom Tulang Korpus Mandibula Tikus dengan Perbedaan Konsistensi Diet
The physical consistency of diet can affect the force exerted during muscle contraction when chewing food from the load sent to the mandible and cause adaptation of bone structure. The mechanical properties of bone are determined by the architecture of the trabeculae covering the walls and spaces. The difference in bone microstructure are influenced by the properties of the atoms that substitute for the composite. This study aimed to analyze the effect of dietary consistency on bone architecture and atomic mineral composition of the mandibular corpus. This study used eighteen male wistar rats aged 3 weeks were randomly divided into three groups, the hard diet (HD), the soft diet (SD) and the liquid diet (LD). After eight weeks the mice were sacrificed. The right mandibular corpus was examined to study the effect of masticatory functional load on the architecture and atomic mineral composition of bone. Qualitative analysis of SEM images showed that the HD group had the best bone architecture compared to the other groups. The atomic composition of Ca, Fe and Ca/P ratio in the HD group were also higher based on SEM-EDX examination. The results of this study on the mandibular corpus showed that masticatory muscle activity through the consistency of the diet consumed could affect the bone quality and quantity of atomic mineral composition. Further research is needed to elucidate the molecular mechanisms of how atomic minerals can play a role in influencing bone quality
Prakiraan Usia Gigi Menggunakan Standar Blenkin (Modifikasi Metode Demirjian) pada Anak Penderita Down Syndrome
Age has an important role in the forensic identification process. Age estimation need to be done accurately in determining a person's age. The use of the Blenkin standard as a method of age estimation to the Javanese population produces accurate results. Chronological age estimation can be known through the dental age which is largely controlled by genetic factors. One of the genetic disorders that is associated as one of the causes of delayed development and eruption of teeth is Down Syndrome. The manifestation of Down syndrome in children's teeth is the delay in the timing and sequence of tooth eruption. The purpose of this study was to assess dental age estimates using the Blenkin standard (modified Demirjian method) in children with Down syndrome. This study is a cross-sectional study using children with Down Syndrome as research subjects, aged 10-16 years and willing to sign an informed consent for further panoramic x-rays. The results of the panoramic X-ray are then assessed using the Blenkin Standard for age estimation. The results showed that the dental age was different from the chronological age, which was 2.8 years for the sample of boys with Down Syndrome and 0.72 years for the sample of girls with Down Syndrome
Karakteristik dan Derajat Keparahan Atrisi pada Narapidana Pengguna Sabu-Sabu (Methamphetamine) di Lembaga Pemasyarakatan Kelas IIA Kabupaten Jember
Using methamphetamine has negative effects on oral health. The negative effect of methamphetamine use is bruxism which causes tooth attrition. It is able to cause masticatory disorders which affect the nutrient intake and reduce the quality of life. Methamphetamine prisoners in Prison Class IIA Jember who represent the methamphetamine users in Jember Regency are group of people who are susceptible to have tooth attrition because of their history using methamphetamine. This research aimed to determine the characteristics and description of severity degree of tooth attrition of methamphetamine prisoners in Prison Class IIA Jember. Methods: This is a description research which use cross sectional approach and was conducted in Prison Class IIA Jember in January 2020. We observed and interviewed 53 prisoners in Prison Class IIA Jember as respondent. Meanwhile, the attrition severity degree was examined by using the clinical judgement with benchmark of occlusal tooth wear index, while prisoners’ characteristics obtained from questionnaire analysis. Most of the respondents were male with the highest level of education is Senior high school, never attended Islamic school based, never get educated in Islamic boarding school, a frequency user with duration of drug use less than 1.5 years, using inhalation method, first experience using drugs in the late teens, unawareness of bruxism habit, experienced sensitive teeth, and keen to eat hard-textured food. The highest severe degree of attrition is moderate with a percentage of 43.4%. The inmates who use methamphetamine have several characteristics which may interfere health and lead to attrition
Gambaran Kesehatan Gigi Mulut dan Jumlah Streptococcus Sp pada Anak Sindroma Down di Kecamatan Patrang dan Sumbersari Jember
Down syndrome is a disorder that causes distinctive physical and mental disorders, causing a slower learning process than normal people. One of the consequences of these physical and mental limitations is the magnitude of dental and oral health problems. To check the state of oral hygiene, DMF-T and OHI-S examinations can be done. In addition, the presence of caries causes, such as Streptococcus sp can be a state of oral hygiene. This study aimed to examine the description of dental and oral health and the effect of the number of Streptococcus sp bacteria in saliva on the incidence of caries in children with Down syndrome at SLB Negeri Patrang, SLB C Taman Pendidikan and Asuhan (TPA) Sumbersari and SLB C Bintoro Regency. Jember. This study was a descriptive study with cross sectional design. This study was held at SLB Negeri Patrang, SLB C Bintoro, and SLB C TPA Sumbersari. This study showed there were differences to the caries incidence and dental hygiene of Down syndrome’s children at SLB Negeri Patrang, SLB C Bintoro, SLB C TPA Sumbersari. Besided it, there were significant differences between the DMF-T index and the colonies of Streptococcus sp, while there was no significant difference of oral hygiene down syndrome children in SLB Negeri Patrang, SLB C Bintoro, SLB C TPA Sumbersari. Briefly, this study showed that the number of Streptococcus sp colonies not frequently correlated to caries incidence and oral hygiene
Jumlah Sel Osteoklas pada Tulang Alveolar Daerah Tekanan Gigi Tikus yang Diinduksi Gaya Mekanis Ortodonti
The mechanical force of orthodontics produces areas of pressure and pull. In the pressure area occurs resorption of alveolar bones carried out by osteoclast cells. The study aims to find out the change in the number of osteoclast cells in the alveolar bone pressure area of mouse teeth that induced mechanical force orthodontics. 36 male rats are divided into 6 groups. Group K: mice are not given a mechanical style of orthodontics. Group P: mechanically styled orthodontics (GMOs). GMOs in mice were administered to the upper jaw molar-1 (M-1) teeth (RA) right and in both RA incisive teeth using Ni-Ti Orthodontic Closed Coil Spring diameter 0.01 inches in orthodontic force of 3.5 oz = 85.05 gr/cm2 = 10 grF for 1 week, 2 weeks and 3 weeks. The results of the study were 1 week (1.99), 2 weeks (1.92), and 3 weeks (1.75). Conclusion of mechanical administration of orthodontic force increases the number of osteoclast cells on the 8th day (1 week), the 15th (2 weeks), and the 22nd (3 weeks). Based on the observation time there was a decrease in the number of osteoclast cells from 1 week to 2 weeks then to 3 weeks but not significant
Gambaran Pemanfaatan Pelayanan Kesehatan Gigi dan Mulut oleh Pasien ODHA di Puskesmas Puger dan Puskesmas Jember Kidul Tahun 2019
HIV-AIDS is a complex health problem and the number of cases increases year by year. The highest number of new HIV-AIDS cases in East Java in 2018 was found in Jember at Primary Health Center (PHC) of Puger and Jember Kidul. In PLWHA (People Living with HIV-AIDS) patients, HIV-AIDS gives manifestation in their oral cavity. PHC plays a role in handling oral health problems of PLWHA and also HIV-AIDS problems. Purpose was to determine the utilization of oral health services by PLWHA in primary health center of Puger and Jember Kidul in 2019. This research was a descriptive study by analyzing secondary data. The data was taken from medical record data of VCT and registration book of oral health services at PHC of Puger and Jember Kidul. In 2019, there were 47 new PLWHA patients at PHC of Puger and there were 36 new and old PLWHA patients with oral health problems at PHC of Jember Kidul. Most of the oral health problems of PLWHA are oral candidiasis. PLWHA with oral candidiasis were treated at VCT, while caries was referred to oral health services. There were no PLWHA who utilize the oral health services in oral health services room at PHC of Puger meanwhile, the research wasn't carried out at the oral health services room of Jember Kidul primary health center due to the COVID-19 pandemic. The utilization of oral health services by PLWHA in PHC of Puger and Jember Kidul was low, and more persuasive approaches were needed to motivate PLWHA