5358 research outputs found
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Circular industry 4.0: an integrative framework
No full textBoth in theory and practice Circular Economy and Industry 4.0 have been historically considered as isolated mechanisms for economic growth, although some scientific contributions have recently highlighted strong synergetic relationships between them. Despite the existence of roadmaps for sustainable operations in Circular Economy through Industry 4.0 or of conceptual frameworks of Industry 4.0 in Circular Economy contexts, we still lack an integrative framework of Industry 4.0 and Circular Economy. Thus, we examine whether and to what extent Industry 4.0 is interdependent and interrelated with Circular Economy and can support the value creation and capture in Circular Economy business models.24-26 June 201
Populismo, tecnocrazia e la globalizzazione delle informazioni: influenza dei social network sull'opinione pubblica nelle consultazioni elettorali
No full text
Social network e tutela dei consumatori: le ultime decisioni delle corti straniere
No full textLa natura del contratto di adesione a Twitter, l'utilizzo dell'advertisement sponsorizzato su Facebook, il vantaggio economico (in denaro o in prodotti) degli influencer su Instagram sono alcuni tra i più recenti casi trattati dalle Corti straniere
Circular economy in the building sector: analysis of a US case study
No full textThe research stream on circular economy business model tries to investigate the managerial practices that companies need to implement in their business model to address the principles of circular economy. Several studies have highlighted two main dimensions of business model on which companies can leverage to implement circular economy principles. On one hand, the value network dimension concerns the creation of value through the management of the supply chain and of the key relationships along the entire supply chain with suppliers, manufacturers and retailers. On the other hand, the customer value proposition and interface dimension concerns the capture of value through the management of relationships with clients, supported by new mechanisms of value transferring such as pay-as-a-service. In this paper, we focus on the dimension of the value network, thus we put emphasis on the Design for X practices in the adoption of circular economy and on the actions conducted by the key partners of the supply chain to push the realization of a circular economy business model. Accordingly, by incorporating the recent contributions on business model innovation in the context of circular economy, a framework has been proposed. Then, we tested the empirical suitability of our framework on a US company operating in the building sector to illuminate on the managerial practices a company in this industry is required to consider in its value network dimension. Accordingly, among the main results, we emphasize the valorization of natural waste through the harmonization of managerial practices, socio-economic regeneration, and sustainable behaviours among the actors of the supply chain, which have been identified as essential for value creation in circular economy business models in the building sector.30 June-4 July 201
Why laparoscopists may opt for three-dimensional view: a summary of the full HTA report on 3D versus 2D laparoscopy by S.I.C.E. (Società Italiana di Chirurgia Endoscopica e Nuove Tecnologie)
No full textBackground. Three-dimensional view in laparoscopic general, gynaecologic and urologic surgery is an efficient, safe and sustainable innovation. The present paper is an extract taken from a full health technology assessment report on threedimensional vision technology compared with standard two-dimensional laparoscopic systems.
Methods. A health technology assessment approach was implemented in order to investigate all the economic, social, ethical and organisational implications related to the adoption of the innovative three-dimensional view. With the support of a multi-disciplinary team, composed of eight experts working in Italian hospitals and Universities, qualitative and quantitative data were collected, by means of literature evidence, validated questionnaire and self-reported interviews, applying a final MCDA quantitative approach, and considering the dimensions resulting from the EUnetHTA Core Model.
Results. From systematic search of literature, we retrieved the following studies: 9 on general surgery, 35 on gynaecology and urology, both concerning clinical setting. Considering simulated setting we included: 8 studies regarding pitfalls and drawbacks, 44 on teaching, 12 on surgeons’ confidence and comfort and 34 on surgeons’ performances. Three-dimensional laparoscopy was shown to have advantages for both the patients and the surgeons, and is confirmed to be a safe, efficacious and sustainable vision technology.
Conclusions. The objective of the present paper, under the patronage of Italian Society of Endoscopic Surgery, was achieved in that there has now been produced a scientific report, based on a HTA approach, that may be placed in the hands of surgeons and used to support the decision-making process of the health providers
Health technology assessment of the available NRTI backbones in Italy
No full textObjectives: Triple therapy with a 2-NRTI backbone is the standard of care approach for HIV treatment. The introduction of emtricitabine/tenofovir alafenamide (FTC/TAF) will alter the HIV drugs market in Italy. The study's aim was to analyse the effects of FTC/TAF introduction and emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) disinvestment, with a Health Technology Assessment (HTA) methodology. Methods: The HTA, considering the 9 EUnetHTA (European Network for Health Technology Assessment) Core Model dimensions, involved 18 Italian Infectious Disease Department clinicians. The assessment compared the 2-NRTI backbones available in Italy; FTC/TAF, FTC/TDF and abacavir/lamivudine (ABC/3TC). Clinician perceptions were collected using validated questionnaires (a 7 level Likert scale, from -3 to +3), and economic modelling (Budget Impact Analysis) was performed. Differences among the groups were studied using ANOVA test. Results: Results from questionnaires showed that FTC/TAF ensures a higher percentage of virological and immunological control compared to FTC/TDF and ABC/3TC (1.36 vs 0.89 and 0.68 respectively; p-value: 0.023). FTC/TAF also presents a better safety profile compared to both FTC/TDF and ABC/3TC (0.93 vs -0.09 and 0.14 respectively; p-value: 0.04). FTC/TAF decreases the burden of adverse events management (0.85 vs 0.10 [FTC/TDF] and 0.26 [ABC/3TC], p-value: 0.016). From an organisational perspective, FTC/TAF could simplify the overall management of drug complications for hospitals, both in the short term (0.60 vs -0.13 [FTC/TDF] and 0.01 [ABC/3TC], p-value<0.001) and in the long term (0.65 vs -0.18 [FTC/TDF] and 0.03 [ABC/3TC], p-value<0.001). The economic modelling revealed a 6% cost saving for the NHS with FTC/TAF introduction and FTC/TDF disinvestment. Conclusions: The introduction of FTC/TAF was found to deliver improvements in efficacy, with a greater chance of virological control, and safety compared with the older 2-NRTI backbones, FTC/TDF and ABC/3TC. A FTC/TDF disinvestment strategy could be cost saving for the Italian NHS, suggesting that FTC/TAF is a dominant alternative.10-14 November 201
