MTA-SZTE Research Group on Artificial Intelligence

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    Az uniós jog megsértése a 2019/1937 számú irányelv átültetésének hiánya miatt

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    Az Európai Unió Bírósága a 2025. március 6-án kelt, Magyarországot elmarasztaló ítéletében kifejtette, hogy az (EU) 2019/1937 számú irányelv határidőn belüli teljes körű átültetésének hiánya szükségképpen sérti az uniós jogot. Az EUB továbbá ismételten megerősítette a jogbiztonság érvényesülésére vonatkozó ítélkezési gyakorlatát is, azaz ha az irányelv kifejezetten előírja, hogy a végrehajtásához szükséges rendelkezésekben hivatkozni kell az irányelvre, vagy hivatalos kihirdetésük alkalmával ilyen hivatkozást kell hozzáfűzni, akkor pozitív átültető jogi aktus elfogadása szükséges

    "Lesznie kell" : Esterházy Péter: Vanni van

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    La representación contemporánea de la caza de nazis y el caso de la serie española "Jaguar"

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    En la era de los contenidos digitales, las películas y series que presentan un fragmento de la historia desempeñan un papel importante en la formación de la memoria histórica nacional y, en ocasiones, internacional. En la mayoría de los casos, estas obras nos cuentan sobre acontecimientos o personajes históricos sobre los que el espectador generalmente ha tenido menos información hasta ver estos productos audiovisuales. Estas obras son películas y series recientes o que se rodaron en épocas anteriores, pero que ahora están disponibles en plataformas de streaming. El objetivo de mi artículo es demostrar cómo se representa la caza de nazis en los largometrajes y series actuales, y examinar un caso concreto español a través de la serie Jaguar (Bambú Producciones, 2021) de seis capítulos, basada en hechos reales, que cuenta la historia de un grupo secreto que intenta capturar a los nazis que llegaron a España durante la dictadura de Franco

    Syndromic Retinitis Pigmentosa : A Narrative Review

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    Retinitis pigmentosa (RP) encompasses inherited retinal dystrophies, appearing either as an isolated eye condition or as part of a broader systemic syndrome, known as syndromic RP. In these cases, RP includes systemic symptoms impacting other organs, complicating diagnosis and management. This review highlights key systemic syndromes linked with RP, such as Usher, Bardet–Biedl, and Alström syndromes, focusing on genetic mutations, inheritance, and clinical symptoms. These insights support clinicians in recognizing syndromic RP early. Ocular signs like nystagmus and congenital cataracts may indicate systemic disease, prompting genetic testing. Conversely, systemic symptoms may necessitate eye exams, even if vision symptoms are absent. Understanding the systemic aspects of these syndromes emphasizes the need for multidisciplinary collaboration among ophthalmologists, pediatricians, and other specialists to optimize patient care. The review also addresses emerging genetic therapies aimed at both visual and systemic symptoms, though more extensive studies are required to confirm their effectiveness. Overall, by detailing the genetic and clinical profiles of syndromic RP, this review seeks to aid healthcare professionals in diagnosing and managing these complex conditions more effectively, enhancing patient outcomes through timely, specialized intervention

    The effect of transcranial direct current stimulation and inhibitory control training on depression and anxiety among post-stroke individuals

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    Recent research has highlighted the role of fronto-parietal brain networks and cognitive control in mood disorders. Transcranial direct current stimulation (tDCS) and computer-based cognitive training are used in post-stroke rehabilitation. This study examined the combined effects ofof computer-based inhibitory control training (ICCT) and anodal tDCS on post-stroke depression and anxiety.Thirty-five participants were randomly assigned to one of three groups: active tDCS treatment (A), sham tDCS treatment with ICCT (T), or active tDCS with ICCT (AT), for a duration of ten days. Primary outcome measures included the Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HAM-D), and Spielberger's State-Trait Anxiety Inventory (STAI-S/T). Statistical analysis was performed using a Mixed-model Analysis of Variance, with supplementary Bayesian analysis.The AT group showed a significant improvement in BDI scores (p < .001), whereas no significant effects were observed on the HAM-D, STAI-T, or STAI-S scales.The combination of tDCS and ICCT reduced depressive symptoms as measured by the BDI; while no significant effects were found with either treatment alone. Further research is needed to explore the mechanisms behind the synergistic effects in the treatment of post-stroke mood disorders

    Dysbiosis is associated with the behavioral phenotype observed in the triple-hit Wisket rat model of schizophrenia

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    Comorbidities between gastrointestinal diseases and psychiatric disorders have been widely reported, with the gut-brain axis implicated as a potential biological basis. Thus, dysbiosis may play an important role in the etiology of schizophrenia, which is barely detected. Triple-hit Wisket model rats exhibit various schizophrenia-like behavioral phenotypes. The present study aimed to compare the diversity and abundance of gut microbiota in Wisket model and control rats; furthermore, to correlate the microbial taxonomic profiles to indices of behavioral change. Tail-flick and Ambitus tests were used to assess acute heat pain sensitivity, and record exploration and locomotor activity along with motivation in young adult, control and Wisket model rats. Fecal microbiota composition was profiled by deep sequencing of bacterial 16S rRNA, and it was correlated to behavioral phenotype. Wisket rats exhibited significantly decreased pain sensitivity, lower locomotor activity and exploration, and impaired motivation compared with controls. No significant differences were observed in bacterial alpha diversity between the groups; however, clear differences in community structure were observed. Wisket rats showed decreases in several genera of Firmicutes and Saccharimonas, and increases in Bacteriodetes and Helicobacter phyla compared with controls. Correlation analysis revealed significant associations between the microbiota profile and the behavioral phenotype. This is the first demonstration that fecal microbiota composition is markedly altered in a triple-hit schizophrenia rat model, suggesting the contribution of the microbiota-gut-brain axis in the development of the schizophrenia-like behavioral phenotype. Thus targeting the gut microbiota may be a novel approach to treat such impairments

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