MTA-SZTE Research Group on Artificial Intelligence
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The Effect of Low-Level Laser Therapy to Reduce Pain Caused by Orthodontic Separators: A Randomized, Double-Blind Placebo-Controlled, Split-Mouth Study
Get PDFStudies on the Synthesis of Some Functionalized Azaheterocycles through Oxidative Ring Opening/Ring Closing by Reductive Amination
Get PDFSelected functionalized saturated azaheterocycles have been prepared by ring expansion from their unsaturated counterpart or using substituted cycloalkenes involving oxidative ring opening/ring closing by reductive amination. Studies have been conducted regarding the outcome of the transformations, the effect of the ring strain, and stereocontrol. The synthesized amino acid derivatives possessing either an aryl or fluorine element in their structure might be relevant building blocks for foldamer chemistry
Tumour dimension is a prognostic factor in thymic epithelial tumours : An update analysis from the ESTS thymic database: Tumour dimension in thymic tumours
Get PDFThe 9thTNM proposal for thymic epithelial tumours (TETs) introduced size as category in stage I, confirming tumour infiltration type as descriptor for the other stages. Aim of this study is to evaluate the role of tumour size in TETs considering different possible cut-offs also among different subgroups.Clinical and pathological data of patients from ESTS thymic database who underwent surgery for TETs from1/2000 to 12/2022 were reviewed and analysed. Patients clinical data, tumour characteristics, size and organs infiltration were collected and correlated to overall survival (OS), Disease free Survival (DFS) and Cancer specific Survival (CSS) using Kaplan Meier curves. The log-rank test was used to assess differences between subgroups. A multivariable model was built using Cox-regression analysis including clinical relevant variables resulting significant at univariable (p-value 5 cm(59 %)and without surrounding structures infiltrations (51.3 %). During FUP, a recurrence occurred in 235 (11%) patients, 199 (9.3%) died, 38 due to tumour progression. Multivariable confirmed as independent negative prognostic factors age (p 5 cm (p 5 cm (p = 0.024, p < 0.001 and p < 0.001).Tumour size resulted a significant prognosticator in TETs, and its associations with infiltration permits to identify different prognostic groups
Spatio-temporal diagnosis of few-cycle 3.2 µm pulses from a mid-IR OPCPA system
Get PDFFour-cycle pulses from a 3.2 µm OPCPA system were characterized by spatially resolved Fourier transform spectroscopy, for the first time. Combining the spatio-spectral information with temporal characterization yielded the spatio-temporal structure of the pulses revealing up to now inaccessible details in the mid-IR spectral region. The proposed technique offers efficient and simple characterization for the optimization of MIR OPCPA systems in terms of spatio-spectral couplings. © 2025 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement
