Makara Journal of Health Research
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Biochemical Evaluation of Withania somnifera Root Powder on Adjuvant-Induced Arthritis in Rats
No full textThe present investigation was carried out to evaluate the biochemical effect of Withania somnifera Linn. Solanaceae, commonly known as ashwagandha on adjuvant induced arthritic rats. Results were compared to Indomethacin, a non steroidal anti-inflammatory drug. Arthritis was induced by an intra dermal injection of Complete Freund’s Adjuvant (0.1 ml) into the right hind paw of Wistar albino rats. Withania somnifera root powder (1000 mg/kg/day) and Indomethacin (3 mg/kg/day) were orally administered for 8 days (from 11th to 18th day) after adjuvant injection. After the experimental period, all the animals were sacrificed and serum, liver and spleen samples were collected for further biochemical analysis. A significant increase in the activities of gluconeogenic enzymes, tissue marker enzymes, blood glucose level, WBC, platelet count, erythrocyte sedimentation rate, and acute phase proteins (hyaluronic acid, fibrinogen and ceruloplasmin) was observed in adjuvant-induced arthritic rats, whereas the activities of glycolytic enzymes, body weight, levels of hemoglobin, RBC count, and packed cell volume were found to be decreased. These biochemical alterations observed in arthritic animals were ameliorated significantly after the administration of Withania somnifera root powder (1000 mg/kg/b.wt) and Indomethacin (3 mg/kg/b.wt). Our results suggest that Withania somnifera root powder is capable of rectifying the above biochemical changes in adjuvant arthritis and it may prove to be useful in treating rheumatoid arthritis
Energy Consumption during Lactation and Duration of Breastfeeding At Puskesmas Margajaya Bekasi City in 2014
No full textDespite recommendation for higher energy intake during lactation than during pregnancy, researches at Jakarta and Depok showed that energy consumption during lactation was lower than during pregnancy. The purpose of this study is to investigate the association between individual characteristics and energy consumption during lactation, and to assess the relationship between energy consumption during lactation to duration of breastfeeding among 60 mothers in the working area of PuskesmasMargajayaBekasi City in 2014. This research used a cross-sectional design; data was collected through primary data collection by questionnaire and Semi-quantitative Food Frequency Questionnaire. Analysis was conducted using chi-square technique. The study found that mothers of sufficient age (>27 years old), multiparous, and had low (<2,100 kcal/day) energy intake during pregnancy had significant higher risk to low energy consumption during lactation. Mothers with low energy consumption during lactation had 4 times higher risk of short duration of breastfeeding. It is recommended to provide information on the importance of higher energy intake during lactation due to the higher need to support breastmilk production and also to shift forward the nutrition recommendation regarding additional energy intake during lactation period from month 6 to month 4 due to higher energy requirement that commences when lactating mothers enter the fourth month of lactation
Smoking Behaviors of Street Children in Makassar 2013
No full textStreet children are vulnerable groups of risky behavior like smoking behavior. This study aims to describe smoking and relation with education, living with parents, family, peer influence, and religiosity. Study design was cross sectional study. The population was 990 street children with the sample of 277 street children. Sample selection in accidental sampling with criteria of respondents aged 10-19 years and Muslims. Data were analyzed with chi square test with confidence interval of 95% (α=0.05). Results show that 48% of street children have ever smoked and 37.2% of street children were still smoking in the last 30 days. Then, there is a relationship between living with parents (p=0.002) and levels of religiosity (p=0.023). However, there was no relationship with school status (p=0613), family history (p=0.874), and peer influence (p=0.157) with the smoking behavior of street children. This research suggests to give education about the dangers of smoking, provide religious values for them and involve them in religious social activities, family empowerment approach to parents to guide their children not to smoke, and optimize function of NGOs or shelters for street children
Hardness of Demineralized Enamel with the Application of Toothpaste Containing Green Tea Extract
No full textThe aim of this study was to analyze the influence of toothpastes with or without green tea extract on the enamel hardness. Human teeth were used as specimens and surface enamel demineralization by soaking in 1% citric acid. Teeth that have been demineralized were applied with a toothpaste containing green tea extract with concentrations of up to 15% on the surface of the enamel teeth and then proceed with surface hardness measurement using Knoop system. The results showed that soaking the teeth (enamel) in a demineralized solution has significantly decreased the hardness of tooth enamel. Applications of toothpaste without (0%) and with green tea extract 5% or 10% or 15% on the demineralized enamel surface have increased the enamel hardness significantly. However, no significant differences were seen between the demineralized enamel and enamel applied with toothpaste containing green tea 5% or 10% or 15%. It was concluded that the application of toothpaste containing 5% green tea extract was able to increase the hardness of demineralized enamel.  
The Correlation between Eating Utensils and Place of Sales in the Contamination of Escherichia coli in Food Sold at Campus Food Stalls
No full textUp to now, in general, the safety of food that is sold at any canteens in the campuses, the eating utensils are handled and the food stalls are managed are still uncertain. This research was aimed to understand the correlation between the eating utensils handling and the contamination of Escherichia coli (E. coli) in the food sold by the food vendors in the campus. The cross-sectional design research applied on the food stalls in the university campus in Depok with a total number of 173 consumers as respondents. The variables observed as independent variables were the sanitation of the eating utensils and the sanitation of the dining place. The examination method of the Most Probable Number (MPN) for E. coli was conducted to assess the food’s hygiene. The data analyzed using the chi-square test and followed by the logistic regression. The result showed that more than half of the food samples (59.54%) were contaminated by E. coli. The storage place of the eating utensils was most significantly correlated with the E. coli contamination of the served food with an OR=0.45 (0.21-0.87). Therefore, it is necessary to promote the awareness of this risk and reinforce supervision by the Health Authorities and by the management of the place of sales to provide guidance to the food vendors and to the consumers as well. Further research is recommended to observe the E. coli contamination through clean water, eating utensils, the hands of the consumers and the napkins used to wipe dry the eating utensils
Efficacy of Toothpaste Containing Nano Calcium in Dentin Remineralization
No full textBrushing teeth with toothpaste is the most effective method of removing plaque, preventing dental caries and repairing early caries. This research aims to conduct an efficacy test of toothpaste containing nano calcium as an active ingredient in repairing early caries over two weeks. A double-blind randomized parallel group clinical trial was conducted. Eighteen people were randomly assigned to use the test toothpaste, and eighteen others were assigned to use the control toothpaste. Assessments of early caries with DIAGNOdent Pen were performed before and after two weeks of toothpaste use. The results showed that the test toothpaste was more effective in repairing early caries over two weeks than the control toothpaste. Toothpaste containing nano-calcium has the potential to accelerate the healing of early dental caries
Risk Factors of Hypertension in Menopausal Women in Rejomulyo, Madiun
No full textHypertension is a state of blood pressure ≥140 mmHg (systolic) or ≥90 mmHg (diastolic). Incidence of women hypertension in Rejomulyo from January to November 2013 reached 28.4%, in which 87% were menopausal. Risk factors increased since early menopausal period. The aim of the study was to analyze risk factors of hypertension in menopausal women in Rejomulyo, Madiun. An observational analysis was conducted with cross-sectional study design. Samples were 90 menopausal women aged 50-80 years using stratified random sampling. Bivariate analysis showed association between obesity (p=0.023;CI: 1.4-116.8), abdominal obesity (p=0.002;CI: 1.8-24.9), family history suffering of hypertension (p=0.018;CI: 1.2-7.1), elderly age (p =0.028;CI: 1.2-12.9), high stress level (p=0.001;CI: 2.9-19.4) and often natrium consumption (p=0.001;CI: 2.4-15.2). Multivariate analysis showed that risk factors of hypertension were abdominal obesity (POR adj=9.2 CI: 1.7-50.9), elderly age or >65 years old (POR adj=8.6;CI: 1.6-45.1), high stress level (POR adj=8.6;CI: 2.6-28.3) and often natrium consumption (POR adj=6.4;CI: 1.9-20.5). This study found that risk factors of hypertension were abdominal obesity, elderly age (>65 years old), high stress level, and high natrium consumption. Tawangrejo Health Center should be in collaboration with relevant sectors such as the PKK and health cadres
Epidemiology of Dysmenorrhea among Female Adolescents in Central Jakarta
No full textDysmenorrhea is a naturally occurring condition experienced by female teenagers during menstruation, but numerous reports claimed its tendency to incur a negative impact on them. As a result, it is imperative that we are well informed of the condition in the effort to improve female teenagers’ quality of life. However, data on dysmenorrhea for the area of Central Jakarta is difficult to find. The aim of this research is to illustrate the prevalence, associated factors, impact and treatment for dysmenorrhea. Data for this descriptive research was gathered through questionnaires from 240 teenagers selected by accidental sampling. Data was processed by descriptive statistics and chi-square test to examine its significance. 87.5% of the respondents reported an experience of dysmenorrhea (20.48% mild pain, 64.76% moderate pain, 14.76% severe pain). 43.75% of the respondents reported that the condition has constrained them from conducting their daily activities. Most of the participants reported self-medication for the dysmenorrhea, and 5.6% of them have consulted with a physician for pain. Mothers and friends are considered as sources of information and assistance to treat dysmenorrhea. Significant factors behind this research that are associated with dysmenorrhea are age, volume of menstrual blood and occurrence of premenstrual syndrome
Relationship between Obesity and Periodontal Status in Vietnamese Patients
No full textThis study aims to investigate periodontal status, and the relationship between obesity and periodontal status in patients who first visited the Institute of Traditional Medicine, Ho Chi Minh City, Vietnam. 118 patients aged 18 or older, including 56 obese subjects (BMI≥27.5, mean age: 33.8, males: 11, females: 45) and 62 non-obese subjects (BMI<27.5, mean age: 34.3, males: 4, females: 58) were enrolled for a period of 5 months from February 2014 to June 2014. The information on socio-demographic characteristics and dental habits were collected by questionnaire. Periodontal status (PLI, GI, BOP, PD, CAL) was examined and the anthropometric index was measured. There was significantly higher prevalence of periodontitis (39.3%) in the obese group than the non-obese group (16.4%). Means of GI, BOP, PD, and CAL in obese subjects were significantly higher than those in non-obese subjects. Significantly higher percentages of subjects who had lower education, visited dental offices, scaled and polished their teeth regularly were in the non-obese group than in the obese group. Multiple logistic regression analysis revealed that age (OR=3.10), routine of dental visit (OR=3.34) and obesity (OR=2.79) were risk factors significantly related to periodontitis. Periodontal status in obese subjects was poorer than non-obese subjects. Obesity might be the risk factor for periodontitis in Vietnamese patients
Zinc and Copper Levels in Patients with Primary Hypertension and Normotension
No full textOne of the causes of primary hypertension is an exposure to free radicals. The formation of free radicals in the body can be prevented by taking antioxidants. Zinc and copper are cofactors of endogenous antioxidant enzyme superoxide dismutase. This study aimed to analyze the differences of zinc and copper levels in primary hypertensive and normotensive patients. This was an analytical observational study with cross sectional design and simple random sampling method. Subjects were patients aged 40-70 years at Haji General Hospital consisting of 15 primary hypertensive patients and 15 normotensive individuals (comparison group). Data was collected through interviews and laboratory test of blood samples. Zinc and Copper serum concentrations were measured by AAS. Data were analyzed by chi-square and independent samples t-test. The results showed that the mean levels of zinc and copper in primary hypertensive patients was lower than normotensive. However, statistically there was no difference in zinc serum levels (p=0.852) in the two groups, and there was a significant difference in copper serum levels (p=0.032). It can be concluded that there were differences in copper serum levels between the two groups but not with the levels of zinc