JURNAL KIMIA MULAWARMAN
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IDENTIFIKASI DEKSAMETASON PADA JAMU PENGGEMUK BADAN YANG DIJUAL DI E-MARKETPLACE SHOPEE MENGGUNAKAN KROMATOGRAFI LAPIS TIPIS: DETERMINATION OF DEXAMETHASONE IN WEIGHT GAIN HERBAL SOLD AT SHOPEE\u27S E-MARKET PLACE USING THIN LAYER CHROMATOGRAPHY
Full text linkThe regulation of Indonesian Health Ministry number 007 of 2012 about traditional medicines registration explained that traditional medicines are prohibited from containing Drug Chemicals (DC). The aim of the study was to identify the DC of dexamethasone in Agency Fattening Herbs sold in Shopee e-marketplace. Dexamethasone is a corticosteroid drug used as an anti-inflammatory agent. Long-term use can cause a hormonal effect, iatrogenic chusing syndrome. This study was a qualitative descriptive using thin layer chromatography (TLC). The mobile phase used to identify dexamethasone in this study was Ethyl acetate: Toluen: Methanol (45 : 54: 1) and the solvent used was Chloroform: Methanol (9 : 1). Many of the samples tested were 3, namely X, Y and Z. The results of TLC formed purple stain spots on all three samples that were parallel to the comparison on 254 nm UV light. The price of dexamethasone comparison Rf is 0.53. The Rf value of the sample X was 0.34. The Rf value of sample Z is 0.53. The calculation results of Rf value were analyzed by SPSS with a significant value (p ≤ 0.001). The analysis was continued by the Duncan test to show groups that had differences. Of the three samples Agency Fattening Herbs tested two of them (X and Z) containing Dexamethasone whereas one (Y) does not has Dexamethasone.
Keywords: Agency fattening herbs, dexamethasone, e-marketplace, thin layer chromatograph
PREPARASI MAGNETIT-ASAM FULVAT (Fe3O4-AF) DARI TANAH GAMBUT SERTA APLIKASINYA UNTUK MENGADSORPSI RHODAMIN-B
Full text linkPada penelitian ini dilakukan preparasi adsorben Fe3O4 terlapis asam fulvat (Fe3O4-AF) dari tanah gambut dan diaplikasikan untuk mengadsorpsi zat warna rhodamin B. Sintesis Fe3O4-AF dilakukan dengan metode ko-presipitasi, karakterisasi meliputi analisis FTIR, XRD, SEM dan VSM serta mengetahui kondisi pH optimum adsorpsi rhodamin-B pada Fe3O4-AF. Adsorben Fe3O4-AF berhasil disintesis dengan menunjukkan munculnya spektra FTIR yang khas yakni gugus Fe-O, O-H, C-H, C=C dan C=O. Struktur kristal Fe3O4-AF tidak mengalami perubahan, morfologi permukaan berupa koloid rigid AF tertempel bulatan sferis Fe3O4 dan nilai kemagnetan Fe3O4 menurun dengan adanya AF. Kondisi optimum adsorpsi rhodamin B pada Fe3O4-AF terjadi pada pada pH 3 dengan saya serap 1,96 mg/g
Validasi Metode Penentuang Minyak dan Lemak dalam air Laut dengan Spektrofotometri Inframerah
No full textValidation research method of determining oil and grease in sea water with Infrared Spectrophotometry has been conducted. To obtain valid measurement results, the research stages included measurements in the form of validation parameters such as linearity test, limit detection (LOD), quantization limit (LOQ), recovery, precision, reproducibility, detection limit of method (MDL), instrument validation and measurement uncertainty. The results showed that linearity met the good results with a correlation coefficient (R2) ≥ 0.995; LOD is 0.1 mg/L, LOQ is 0.5 mg/L, % recovery with a range of(104,59 ± 1,73)%; repetition and reproducibility was expressed as % SBR <% KV Horwitz, MDL is 0.2745 mg/L. Based on the results of this study, infrared spectrophotometry methods can be used in determining oil and fat in seawater samples with valid results.
Keywords: method validation, oil and greace, infrared spectrophotometry.Penelitian validasi metode penentuan minyak dan lemak dalam air laut dengan Spektrofotometri Inframerah telah dilakukan. Untuk mendapatkan hasil pengukuran yang valid, maka dilakukan tahapan penelitian meliputi pengukuran berupa parameter validasi seperti uji linieritas, limit deteksi (LOD), limit kuantisasi (LOQ), recovery, presisi, reproducibility, batas deteksi metode (MDL), validasi instrumen serta ketidakpastian pengukuran. Hasil penelitian menunjukkan pengukuran linieritas memenuhi hasil baik dengan koefisien korelasi (R2) ≥ 0,995; LOD sebesar 0,1 mg/L, LOQ sebesar 0,5 mg/L, % recovery dengan rentang (104,59 ± 1,73)%; pengulangan dan reproducibility dinyatakan sebagai %SBR < % KV Horwitz, MDL sebesar 0,2745 mg/L. Berdasarkan hasil penelitian ini, metode spektrofotometri inframerah dapat digunakan dalam penentuan minyak dan lemak pada sampel air laut dengan hasil yang valid.
Kata kunci: Validasi metode, minyak dan lemak, spektrofotometri inframera
PENURUNAN COD DAN TSS PADA LIMBAH LAUNDRY MENGGUNAKAN ELEKTRODA ALUMINIUM (Al) DAN TEMBAGA (Cu) PADA METODE ELEKTROKOAGULASI
Full text linkA research about reduction of COD and TSS from laundry waste with Electrocoagulation method using Al and Cu electrodes in COD and TSS reduction parameters has been done. In this research, the voltage and optimum time determited based on occurred in electrocoagulation process. The determination of COD and TSS in the contact time was 60 minutes with the value of COD was 90.5645% and TSS 63.7279%. The value of voltage optimum was 12 Volt, obtain COD was 90.2392% and TSS 60.7052%.Penelitian tentang penurunan COD dan TSS pada limbah laundry dengan metode Elektrokoagulasi menggunakan elektroda Aluminium (Al) dan Tembaga (Cu) pada penurunan COD dan TSS telah dilakukan. Dalam penelitian ini ditentukan tegangan dan waktu optimum berdasarkan kejernihan yang terjadi pada proses Elektrokoagulasi. Hasil penelitian menunjukkan penurunan COD dan TSS pada waktu kontak 60 menit dengan waktu COD sebesar 90,5645% dan TSS sebesar 63,7279%. Kuat tegangan optimum yang diperoleh adalah 12 Volt, menghasilkan penurunan COD sebesar 90,2392% dan TSS sebesar 60,7052%
PERBANDINGAN KINERJA ANALITIK HASIL PENENTUAN ION LOGAM Pb DENGAN MENGGUNAKAN SPEKTROFOTOMETER SERAPAN ATOM DI BERBAGAI LABORATORIUM SAMARINDA
Full text linkThe study about the comparison of analytical performance of the determination of Pb metal ions using Atomic Absorption Spectrophotometer in various laboratories in samarinda has been conducted. The validated methods are linearity, detection limits, quantity and precision limits. The results showed, a standardized regression test obtained by laboratory A, a value of R2 ≥ 0.4103, laboratory B a value of R2 ≥ 0.983 and laboratory C, a value of R2 ≥ 0.000. The detection limit found at laboratory A was 0.6728 µg/L, laboratory B was 0.1989 µg/L and laboratory C was 0.0001 µg/L. The quantization limit obtained by laboratory A was 0.6817 µg/L, laboratory B was 0.6063 µg/L and laboratory C was 0.0001 µg/L. The precision test of laboratory A was 7.2208, laboratory B was 5.4557 and laboratory C was 0,000. The result of determining Pb of gas station soil samples in laboratory A is 0.737 µg/L and laboratory B is 0.391 µg/L, so that means they have exceeded the quality standards set by the Indonesian National Standard (INS)
Studi Penambatan Molekul Flavonoid Pada Reseptor α-Glukosidase menggunakan PLANTS
Full text linkABSTRACT
Plants that contain flavonoids are widely used in traditional medicine. Flavonoids can reduce blood glucose levels with their ability as anti-oxidants. The purpose of this study was to determine natural compounds from flavonoid derivatives that have good affinity and conformation and their interactions in inhibiting α-glucosidase (an enzyme that breaks down carbohydrates into glucose) and determine the sequence of ligands that interact more strongly with α protein / enzyme α-glucosidase. Molecular docking is a computational method that aims to imitate the interaction of a ligand molecule with the protein it targets in in-vitro tests. Molecular docking between flavonoids and α-glucosidase receptors was carried out using the PLANTS method to see its affinity. The flavonoids used as ligands were flavones, flavanols and chalcone with the results of the docking scores respectively, -65.41, -64.39 and -63.07 where the standard ligand used in this study was deoxynojirimycin (-77.12). In the active side of the α-Glucosidase enzyme that binds to flavonoid ligands is Gly 555, Glu 526 and Pro 556.
 
Studi Perubahan Ukuran Pori Zeolit Y Berdasarkan Pengaruh Variasi Rasio Si/Al, Variasi Kation Dan Penambahan Molekul Organik Menggunakan Metode Mekanika Molekuler
Full text linkPemodelan struktur zeolit Y telah diteliti dengan variasi rasio Si/Al, variasi kation dan penambahan molekul organik menggunakan metode mekanika molekuler. Pemodelan zeolit dilakukan dengan membuat kerangka struktur satu unit sel zeolit Y. Zeolit Y dengan energi optimasi terendah (Si/Al = 4,3) dipilih untuk studi pengaruh penambahan kation (Na+, K+, Ca2+, Mg2+) dan molekul organik (C4H9OH, C5H11OH, C6H5OH) pada diameter pori. Hasil penelitian menunjukkan struktur zeolit Y dengan impregnasi kation K+ dan molekul organik C4H9OH memiliki diameter pori terbesar yaitu 16,0303 dan 15,9126
STUDI KOMPUTASI SEMIBUCKMINSTERFULLERENE SEBAGAI PENYIMPAN HIDROGEN MENGGUNAKAN METODE PERHITUNGAN DENSITY FUNCTIONAL THEORY.
Full text linkHydrogen is an alternative energy source for fossil fuels. One of molecules that have an ability to store hydrogen is Semibuckminsterfullerene. This study was conducted to find out the optimum distance in adding hydrogen and the phenomenon of energy produced when adding hydrogen from 10 molecules to 100 molecules. Semibuckminsterfullerene was calculated using Density Functional Theory method, B3LYP with a basis set of 6-31G*. The optimum distance of Semibuckminsterfullerene with hydrogen was 3 ? Furthermore, the results of adding hydrogen from 10 to 100 molecules showed a decrease in energy due to the bowl-shaped structure of Semibuckminsterfulleren
ANALISIS RHODAMIN B PADA SAUS TOMAT YANG BEREDAR DI SAMARINDA MENGGUNAKAN SPEKTROFOTOMETER UV-VIS
Full text linkAbstract
Analysis of rhodamine B in tomato sauce which is distributed in Samarinda city have been done. The identification are used chromatography paper and spectrophotometer UV-Vis in wavelength of 553nm. The result of research are showed in 5 of 20 samples that identified are positive of rhodamin B, which is tomato sauce in spring rools are 2.865 mg/L, tomato sauce in sausage are 2.033 mg/L, tomato sauce in meatball snacks are 2.008 mg/L, tomato sauce in cireng snacks are 1.058 mg/L, and the tomato sauce in tofu snacks 1.756 mg/L.
Keywords: Rhodamine B, Chromatography Paper, Spectrophotometer UV-Vi