JURNAL KIMIA MULAWARMAN
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ISOLASI SENYAWA ALKALOID DARI DAUN SIDAGURI (Sida rhombifolia L.)
Full text linkThe secondary metabolite compound was isolated from sidaguri (Sida rhombifolia L.) leaves. The diethylether extract was subjected to a column chromatography with a mixture of chloroform:methanol (7:3) was obtained as amorf (59 mg). The FT-IR and 1H-NMR spectrum indicated the isolated compound was alkaloid compound.Keywords : Sidaguri (Sida rhombifolia L.), column chromatography, alkaloi
UJI TOKSISITAS (Brine Shrimp Lethality Test) DAN AKTIVITAS ANTIOKSIDAN DARI DAUN SINTRONG (Crassocephalum Crepidioides) DENGAN METODE 2,2-diphenyl-1-picrylhidrazil (DPPH)
Full text linkThe phytochemical test, brine shrimp lethality test and antioxidant activity test on secondary metabolits of terap (Artocarpus odoratissimus B.) leaves has been completed. The leaves samples are extracted by masseration method that is concentrated by using rotary evaporator. The total extract are fractioned with n-hexane and ethyl acetate. Based on secondary metabolits phytochemical test of terap (Artocarpus odoratissimus B.) leaves showed that total extract and Ethyl Acetat fraction extract contains alkaloids, phenolics, flavonoids, saponins, steroids and triterpenoids. N-hexane fraction extract contain alkaloids, steroids and tritepenoids. In brine shrimp lethality test, the increase larvae death data was recorded and processed using SAS Probit Analysis to determine the Lethal Concentration 50 % (LC50) value. The results of this test showed that the most active extract is metanol extract with LC50 value of 88.0227 ppm. Based on the antioxidant activity by scavenging activity of DPPH used spectrophotometry was obtained that Inhibition Concentration 50% (IC50) of total extract is 369.0833 ppm, extract of n-hexane fraction is 1532.267 ppm and extract of ethyl acetat fraction is 82.89003 ppm
STUDI AB INITIO GRAFIT BATUBARA SEBAGAI MATERI PENYIMPAN HIDROGEN
No full textCalculation of density functional theory (DFT) is carried out to investigate the adsorption of six molecules of H2 molecules on a graphite planar layer with a doping of alkali metal (Li, Na, and K). We reported that the DFT-GGA method, the presence of alkali metals on graphite, and H2-(GICs), have changed the interaction and the electronic system. We also reported that the ratio increased electron transfer from K to Na and Li. The calculation of the charge density shows that the increase in energy due to the transfer of electrical charge from GICs to six molecules of H2. This changes the electronic properties of graphite that are important in applications such as hydrogen storage.Keywords: Molecule Hydrogen, Graphite Intercalated Compounds, Density Functional Theor
UJI FITOKIMIA DAN AKTIVITAS ANTIOKSIDAN DARI EKSTRAK ETANOL BIJI KELENGKENG (Euphoria Iongan STEUD) DENGAN METODE PERENDAMAN RADIKAL 2,2-DIPHENIL-1-PICRYLHIDRAZYL (DPPH)
No full textKelengkeng fruit already well known for Indonesian society. Not only from the contents of the fruit, but Kelengkeng also have many other beneficial from the seed, leather, root and leaves that useful for human health. In this research, phytochemical and antioxidant activity test have been done. Antioxidant activity test was carried out with scavenging test to 2,2-diphenyl-1-picrylhidrazil (DPPH) radical. On antioxidant activity test, mix of extract and DPPH are incubated for 30 minutes at 37oC, then the absorbance measured at λ = 517 nm using spectrophotometer. The absorbance from sample, blank and negative control are converted as Antioxidant Activity Absorbance (AA%). Based on result of phytochemical etanol extract, Kelengkeng contains phenolic compounds. And based on antioxidant activity test with DPPH radical scavenging method by spectrophotometer, ethanol extract of Kelengkeng has antioxidant activity about EC50(72.23±2.55) while Vitamin C as comparison has antioxidant activity about EC50(6.07±0.36).Keywords: Kelengkeng, phytochemical, antioxidant activity and DPP
Pengaruh Pemberian Ekstrak Etanol Daun Kecapi (Sandoricum koetjape (Burm.f.) Merr.) Terhadap Penurunan Kadar Kolesterol Total pada Mencit Jantan (Mus musculus)
Full text linkThe research about utilization of ethanol extract form leafkecapi (Sandoricum koetjape (Burm.f.)Merr.)has been done, it proved could decrease total cholesterol levels in male mice (Mus musculus). In this research sample macerated with ethanol 96% and then concentrated by rotary evaporator, and gained 15.6% of yield. Based on the results of phytochemical test, secondary metabolites compound that contained in bark kecapi are alkaloid, flavonoid, triterpenoid, steroid, phenolic and saponin. On antihiperkolesterolemia activity test by using male mice, there are several treatments that negative control (-), positive control (+) and three treatment with different doses i.e. a low doses (9.5 mg/kg BB), middle doses (19 mg/kg BB) and high doses (38 mg/kg BB). The parameter measured was blood serum of male mice by using a Cholesterol Test Strips. From this test it showed that the effectiveness of decreased total cholesterol level doses of 19 mg/kg BB showed total cholesterol level under 100 mg/dL. Keywords: Leaf kecapi (Sandoricum koetjape (Burm.f.) Merr.), Phytochemicals test, Total cholesterol levels, Cholesterol test strips
Optimasi Suhu Reaksi Transesterifikasi Pada Minyak Jerami Padi (Oryza sativa L.) Menjadi Biodiesel Dengan Menggunakan Katalis CaO Dari Kulit Telur Ayam)
Full text linkThe research on optimization of transesterification temperature for production of biodiesel from rice straw oil (Oryza sativa L.) using CaO catalyst derived from the chicken egg skin has been conducted. Production of biodiesel was conducted at varied temperatures, namely 30oC, 40oC, 50oC, 60oC and 70oC. The fatty acid compositions of the transesterification products were determined by using GC-MS and the physical and chemical characteristics were determined using SNI Methods 04-7182-2006. The AAS result suggested that the chicken egg skin contained 91.41% CaO. The optimum transesterification temperature was 60oC producing 90,8405% methyl ester. The results of GC-MS showed that the highest percentage of fatty acid was methyl oleic (44.56%).The research on optimization of transesterification temperature for production of biodiesel from rice straw oil (Oryza sativa L.) using CaO catalyst derived from the chicken egg skin has been conducted. Production of biodiesel was conducted at varied temperatures, namely 30oC, 40oC, 50oC, 60oC and 70oC. The fatty acid compositions of the transesterification products were determined by using GC-MS and the physical and chemical characteristics were determined using SNI Methods 04-7182-2006. The AAS result suggested that the chicken egg skin contained 91.41% CaO. The optimum transesterification temperature was 60oC producing 90,8405% methyl ester. The results of GC-MS showed that the highest percentage of fatty acid was methyl oleic (44.56%)
UJI TOKSISITAS DAN AKTIVITAS ANTIBAKTERI BERBAGAI FRAKSI EKSTRAK DAUN TANAMAN KAMBOJA (Plumeria acuminate Ait.)
Full text linkResearch about phytochemical, brine shrimp lethality and antibacterial activity tests in each fraction from kamboja leaves (Plumeria acuminate Ait.) from Loa Janan, East Kalimantan has been carried out. Plumeria acuminate Ait. leaves was extracted with ethanol and then concentrated by using rotary evaporator. The total extract was fractioned with n-hexane, and ethyl acetate. Based on the secondary metabolites phytochemical test of the Plumeria acuminate Ait. leaves show that total extract is contain alkaloid, steroid, and phenolic. n-hexane fraction is contain steroid. Ethyl acetate fraction is contain steroid. Ethanol-water fraction is contain alkaloid and phenolic. Brine shrimp lethality test exhibit mortality rate of Artemia salina (L) by Probit SAS analysis to determine lethal concentration 50% (LC 50 ) value. The test show that the most active was ethyl acetate fraction with LC 50 value of 44.7968 ppm. Antibacteria activity test of extracts for Staphylococcus aureus bacteria (positive Gram) and Escherichia coli (negative Gram) was carried out by paper disc method. The test showed that the most active were ethyl acetate fraction with minimum inhibitor consentration of 1.563% which clear zone diameter was 5.3 mm on Staphylococcus aureus bacteria and 6.3 mm on Escherichia coli bacteria
UJI TOKSISITAS DAN AKTIVITAS ANTIBAKTERI EKSTRAK DAUN MERAH TANAMAN PUCUK MERAH (Syzygium myrtifolium Walp.) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli
Full text linkA research aims to know the toxicity of Pucuk Merah (Syzygium myrtifolium Walp.) red leaves extracts against brine shrimp Artemia salina Leach and its bioactivity against Escherichia coli and Staphylococcus aureus has been carried out. The dried samples were macerated with ethanol and were fractionated with n-hexane, ethyl acetate and ethanol-water. Phytochemical test showed the presence of alkaloids, triterpenoids, steroids, saponins, phenolic and flavonoid in ethanol extract. n-Hexane fraction contained alkaloids, triterpenoids and steroids, ethyl acetate fraction contained alkaloids, triterpenoids, phenolic and flavonoid while ethanol-water fraction contained triterpenoids, saponins and phenolic. Brine Shrimp Lethality Test showed that ethyl acetate fraction had the highest bioactivity in Artemia salina Leach with LC50 values of 149.8600 ppm. Antibacterial activity test using agar diffusion method showed that ethyl acetate fraction had the highest inhibiton against Staphylococcus aureus whereas total extract had the highest inhibition against Escherichia coli with MIC values of 0,5%. These results showed that Syzygium myrtifolium Walp. red leaves extract potential as an antibacterial agent.Keywords: Syzygium myrtifolium Walp., Toxicity, Antibacteria
STUDY SENYAWA KIMIA DALAM FASE EKSTRAK ETIL ASETAT SIMPLISIA Cinnamomum spp. Secara KCKT dan KG-SM
No full textCinnamomum burmanii (Nees n’ Th. Nees) Blume, Cinnamomum culilaban (L.) J.S. Presl dan Cryptocarpa massoy (Oken) Kosterm are a rare plant species that grow in Indonesia. Species with this same of genus (Cinnamomum) is a potential in the field of medicine, but the comparison of the composition and concentration of the chemical content has not been known so their utilization in medical applications is not optimal. Therefore, the research was conducted in order to analyze of chemical compounds in ethyl acetate extracts phase of three plants by chromatography, They were the HPLC (High Performance Liquid Chromatography), and GC-MS (Gas Chromatography Mass Spectrometry) analysis. The analysis was done of the ethyl acetate extract phase in order to identify of chemical compounds which largely composed of essential oils. Based on the results of HPLC analysis, with using by the reference standards of eugenol showed that in Cinnamomum burmanii and Cinnamomum culilaban (L.) J.S. Presl identified contain of eugenol essential oils, 0.18% and 3.11% respectively. Based on the result of GC-MS analysis, Cinnamomum burmanii was found two components of chemical compounds main with the largest og percentage, They were sinamaldehid (90.24%) and coumarin (53.46%) compounds. On the Cinnamomum culilaban (L.) J.S. Presl was found four components of chemical compounds main, They were metileugenol (40.68%), verbanone (14.58%), terpinol (8.74%) and spathulenol (8.12%) compounds. Later in the Cryptocarpa massoy (Oken) Kosterm was found three components of chemical compounds main, They were massoyalakton (73.64%), butanoat acid (12.25%) and pentadekanoat acid (9.76%) compounds
KAJIAN PERUBAHAN UKURAN RONGGA ZEOLIT RHO BERDASARKAN VARIASI RASIO Si/Al DAN VARIASI KATION ALKALI MENGGUNAKAN METODE MEKANIKA MOLEKULER
Full text linkThe structure modeling of zeolite RHO with variation of Si/Al ratio (5; 4.33; 3.8; 3.36; 3; 2.69; 2.43; 2.2; 2) and variation of alkaline cations (Li+, Na+, K+, Rb+, Cs+, Fr+) calculated by the molecular mechanics method has been investigated. The result shows that the structure of zeolite RHO with Si/Al ratio 3.36 has the most stable structure with a minimum energy 2652.0308 kcal/mol. The most stable structures of zeolite RHO impregnated with cation is that impregnated with Fr+ (alkaline) with a minimum energy 3006.6587 kcal/mol. The result shows that the zeolite RHO structure with cations Fr+ (alkaline) has the largest pore diameter which potentially has the best adsorption capacity.The structure modeling of zeolite RHO with variation of Si/Al ratio (5; 4.33; 3.8; 3.36; 3; 2.69; 2.43; 2.2; 2) and variation of alkaline cations (Li+, Na+, K+, Rb+, Cs+, Fr+) calculated by the molecular mechanics method has been investigated. The result shows that the structure of zeolite RHO with Si/Al ratio 3.36 has the most stable structure with a minimum energy 2652.0308 kcal/mol. The most stable structures of zeolite RHO impregnated with cation is that impregnated with Fr+ (alkaline) with a minimum energy 3006.6587 kcal/mol. The result shows that the zeolite RHO structure with cations Fr+ (alkaline) has the largest pore diameter which potentially has the best adsorption capacity