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pH dependent structures of bovine serum in solution by small angle neutron scattering
No full textThe pH-dependent structures of the bovine serum albumin (BSA), under physiological conditions that permit enzymatic activity, were investigated by small-angle neutron scattering (SANS). The unfolding behavior of BSA in solution is important to understand the mechanism of protein aggregation due to protein conformational change. The information of protein structure is crucial to design the perfect protein-based drug delivery device. This information will be useful as a complementary data of BSA crystal structure in static state. The structure of BSA in solution was found to be heart shaped, nearly identical to bovine serum albumin crystal structure. The globular heart shaped structure of BSA was still maintained at alkaline pH range of 7 to 11. It underwent partial unfolding at pH 5 and continued to unfold at pH 3. The unfolded-structure of BSA shows that the globular structure started to change into a cylinder-like structure at pH 3 which was clearly shown in Kratky plot. These results were confirmed with ab initio low-resolution shape calculation model analysis using GNOM and DAMMIF in obtaining the three-dimensional protein structure model
Nurses\u27 knowledge and practice towards prevention of surgical site infection
No full textSurgical Site Infection (SIS) is a common healthcare-associated infection that significantly impacts patient safety and financial losses for health systems. Enhancing nurses\u27 knowledge and practice is an essential component in the prevention of the spread of infection. The study aims to assess the knowledge and practice of preventing surgical site infection among nurses. A cross-sectional study was conducted among 306 nurses in two public hospitals in Malaysia. Data were obtained from selfadministered questionnaires and analyzed using the IBM Statistical Packages for Social Science (SPSS) Window Version 23. This study revealed that 85.3 % of nurses had good knowledge, and 97.7 % had good practice regarding SSI prevention. However, there was no significant difference between the nurses\u27 knowledge and practice towards Prevention SSI (x2 : 1.10p-value: 0.28). There was a statistically significant association between working unit/ward and the total knowledge score (x2:24.51p-value: 0.01). Nurses who worked in the Operation Theatre were found to have higher percentage of good knowledge (n: 10835.3%). It can be concluded that the nurses had good knowledge and practice regarding surgical site infection. Successful strategies of infection control measures were the well-structured guidelines, continuing education programs, adequate supervision, good support, and regular basis of the necessary consumables and supplies
Factors associated with customers\u27 satisfaction in online purchasing: a study in a malaysian public University
No full textImmune-genetic algorithm(IGA) with local search for intrusion detection system in computer network
No full textThe Internet provides almost unlimited connectivity to the online world that is widely used in our daily lives nowadays. As for borderless connections, inventors have to face great challenges in providing the greatest quality of service specifically in terms of security. Even with existing security measures such as firewalls, Intrusion Detection System (IDS) and antivirus to protect the network, the network is still vulnerable and its resources can be compromised by third parties. This problem highlights the need to address network intrusion problems efficiently. By formulating a specific algorithm for this problem, the purpose of this study is to examine the performance of improvised Genetic Algorithms for network intrusion problems. Based on the 1999 KDD Cup data set with various disruptions simulated from the military network, this research was conducted based on this standard dataset. The performance in terms of average intrusion detection rate and false alarm rate of the proposed method and other available techniques were analyzed to evaluate and determine the best performance. The combination of Genetic Algorithm, Immune Algorithm and local search has produced good detection with acuracy rate of 98.91% and has the potential to be further investigated for other research areas
Kemahiran meta kognitif kanak-kanak dalam penggunaan perisian dan peranti input tanpa sentuhan leap motion
No full textKemahiran metakognitif memainkan peranan penting bagi kanak-kanak untuk belajar bagaimana mengurus, mengawal dan memikirkan cara belajar. Artikel ini menerangkan kajian mengenai penggunaan peranti input tanpa sentuhan dalam mengembangkan kemahiran metakognitif kanakkanak dalam persekitaran pembelajaran. Kajian ini menggunakan kajian kes deskriptif dengan seorang kanak-kanak berusia empat tahun menggunakan peranti tanpa sentuhan Leap Motion Controller dengan tiga jenis perisian aplikasi. Kajian ini mengikuti Model Meta Kognitif Pemantauan oleh Flavell yang merangkumi empat kelas fenomena dan hubungannya. Artikel ini menerangkan penemuan dari sesi temu ramah dengan tiga orang guru, rakaman video dan sesi pemerhatian berstruktur. Penemuan menunjukkan bahawa bukan sahaja tahap kemahiran metakognitif untuk kanak-kanak yang terpilih ini meningkat, ia juga menunjukkan peningkatan kemahiran motor halus. Penggunaan peranti input tanpa sentuhan mempunyai kaitan dengan pengalaman kanak-kanak, kesesuaian interaksi dan antara muka aplikasi, dan kemampuan kanak-kanak dalam berlatih dan mengaplikasikan isyarat dan gerakan jari dan tangan. Kesimpulannya, kanak-kanak ini bersedia menggunakan peranti input tanpa sentuhan untuk pembelajaran abad ke-21. Implikasinya, peranti input tanpa sentuhan boleh digunakan dalam aktiviti pembelajaran untuk mengembangkan kemahiran metakognitif dalam kalangan kanak-kanak generasi muda
Challenges Counselors Face in Effecting School Counseling Programs for Academic Achievement of Secondary School Students in Kiambu County, Kenya
No full textPrecocious Puberty and The Self Esteem of Preadolescent Girls
No full textThis article examines the relationship between precocious puberty and the
self-esteem of preadolescent girls in public primary schools in Kiambu
County, Kenya. This article introduces the two variables precocious puberty
and self-esteem, reviews the literature on the relationship between the
physical, biological, cognitive, and cultural changes of precocious puberty as
they relate to the self-esteem of adolescent girls, discusses the findings of the
study, and makes conclusions and recommendations. The sample population
was 410 preadolescent girls and 8 class teachers, who were purposively
sampled from 12 randomly, selected public primary schools in Kiambu
County. Primary data was collected using three instrumentsa questionnaire
structured interviews and focus group discussions. The instruments were pilot
tested on 36, 8-12 years old girls from 3 public primary schools in the study
location who were omitted from the actual study. The qualitative data was
analysed using the content analysis method, while the quantitative data was
analysed using the Statistical Package for Social Sciences (SPSS) version 26.
Analysed data was presented using tables and figures. Statistical data indicated
that there was a significant relationship (?=0.354, p=0.000) between
precocious puberty and the self-esteem of pre-adolescent girls. This was
confirmed by the responses from both interviews and focus group discussions.
Given these findings, the researcher study concluded that earlier pubertal
maturation as indicated by breast development before age 8 and the onset of
menstruation before age 12 can lead to low self-esteem in preadolescent girls.
The article recommends that awareness of the incidence of precocious puberty
and its relationship with the self-esteem of preadolescent girls be created among parents, teachers, peers, policymakers, and other stakeholders so that
the negative effects from the incidence can be mitigated
Pelaksanaan Pengajaran dan Pembelajaran Hadis dalam Pendidikan Islam Sekolah-Sekolah Menengah Harian di Negeri Perak
No full textKertas kerja ini adalah untuk mengenal pasti pelaksanaan pengajaran dan
pembelajaran hadis dalam pendidikan Islam sekolah menengah di negeri Perak.
Bentuk penyelidikan ini menggunakan kaedah kuantitatif. Seramai 269 orang
guru pendidikan Islam di sekolah menengah harian di negeri Perak dipilih
sebagai responden kajian yang menggunakan teknik persampelan rawak. Data
kajian telah dianalisis secara deskriptif menggunakan Statistical Package for
Social Sciences (SPSS) untuk mendapatkan kekerapan, peratus, min sisihan
piawai. Dapatan kajian pada konstruk peruntukan masa berada pada tahap
sederhana tinggi (min=3.51, s.p =0.3). Manakala dapatan bagi konstruk Bahan
Bantu Mengajar skor min keseluruhan item ialah (min=3.75, s.p=0.15) dan
interpretasi adalah sederhana tinggi dan konstruk bagi kaedah pengajaran guru
(kitabah) skor min keseluruhan item ialah (min=4.65, s.p=0.23) dan
interpretasi pada tahap tinggi Kesimpulannya, dapatan utama kajian
menunjukkan bahawa guru dapat melaksanakan kaedah pengajaran dengan
baik untuk mempengaruhi pencapaian pelajar. Walaupun begitu peruntukan
masa mengajar dan kemudahan bahan bantu mengajar perlu dipertingkatkan.
Implikasi kajian menunjukkan pihak berkenaan perlu menambah peruntukan
masa pengajaran dan memberi pendedahan penggunaan bahan bantu mengajar
kepada guru, agar pelajar boleh menguasai dengan dan mempertingkatkan
amalan sunnah di dalam kehidupan seharian sebagaimana pengajaran yang
diperolehi daripada pembelajaran hadis di sekolah
Sikap Guru Terhadap Perubahan di Sekolah Kebangsaan di Semenanjung Malaysia
No full textKajian ini bertujuan untuk mengenal pasti tahap Sikap Guru Terhadap
Perubahan (SGTP) dalam kalangan guru di Sekolah Kebangsaan (SK) di
Semenanjung Malaysia. Secara khususnya, kajian ini bertujuan untuk
mengenal pasti tahap SGTP berdasarkan dimensi Kognitif, Afektif dan
Tingkah Laku. Kajian ini mengaplikasikan kaedah kuantitatif yang
menggunakan pendekatan tinjauan soal selidik. Seramai 384 orang guru SK
merupakan responden dalam kajian ini. Dapatan kajian ini dianalisis secara
deskriptif dengan menggunakan skor min dan sisihan piawai. Dapatan kajian
ini menunjukkan tahap SGTP secara keseluruhannya berada pada kuadran
Penerimaan (Min=4.38, SP=.57). Selain itu, dapatan kajian juga
menunjukkan dimensi Kognitif (Min=4.53, SP=.71), dimensi Afektif
(Min=4.18, SP=.68) dan dimensi Tingkah Laku (Min=4.43, SP=.59) SGTP
berada pada kuadran Penerimaan. Kajian ini dapat menyumbang kefahaman
kepada para guru tentang kepentingan sikap mereka terhadap perubahan yang
dilaksanakan di sekolah. Dapatan kajian ini memberi makluman kepada pihak
berkaitan untuk merancang program atau latihan yang sesuai bagi
meningkatkan SGTP di sekolah
