446494 research outputs found
Sort by
Reliability-oriented Stochastic Optimization of Integrated Energy Systems Under Extreme Weather Conditions: A Case Study in Ningbo, China
No full textAs extreme weather events become more frequent and severe, energy systems face growing challenges from increasing demand and equipment failures. This study presents a climate-resilient design framework through a case study of Ningbo, China—a coastal city facing typhoon risks. Using real energy demand data and operational parameters from a Ningbo energy center, a multi- scenario analytical model is developed to evaluate combined effects between extreme weather patterns, equipment vulnerability, and demand fluctuations. Three adaptation strategies are explored: equipment addition, energy storage integration, and active load optimization. The methodology employs NSGA-II multi-objective optimization and robust analysis techniques to systematically evaluate solutions under extreme conditions. Results show that equipment addition consistently achieves the best cost-reliability trade-off, while energy storage becomes more valuable under severe typhoon conditions. The active load strategy offers moderate improvements but is limited under extreme events. This work integrates real-world data and coordinates multi-strategy evaluation, providing quantitative insights into the resilience benefits of each approach. The proposed framework can be adapted to other regions and extreme weather types, offering practical guidance for designing robust energy systems in the face of climate change
Entanglement assisted via Kerr effect in exciton-optomechanics
No full textEntanglement lies at the core of numerous quantum information processing applications. A main obstacle against implementing powerful quantum information tasks is decoherence that degrades, or even destroys, entanglement. Therefore, developing strategies to mitigate decoherence is essential for practical implementations. Here, we propose a scheme to enhance exciton-exciton entanglement in an exciton-optomechanical cavity incorporating a Kerr medium. Under experimentally feasible conditions, we demonstrate that the Kerr nonlinearity not only strengthens excitonic entanglement, but also allows it to persist over a wide range of operating parameters. While strong exciton-phonon coupling is required for entangling the two excitonic modes in the Kerr medium-free case, we show that such coupling is no longer necessary when the Kerr interaction is introduced. Remarkably, the presence of the Kerr medium enables the excitonic entanglement to survive up to room temperature without requiring a very high mechanical quality factor. Our scheme provides a promising route for generating robust entanglement and may open new possibilities for quantum information applications
Development and Validation of an HPTLC Method for Simultaneous Estimation of Etofylline and Salbutamol
No full textA precise, robust, and cost-effective High-Performance Thin Layer Chromatography (HPTLC) method was developed and validated for the simultaneous estimation of Salbutamol and Etofylline in bulk and combined pharmaceutical dosage forms. Chromatographic separation was achieved on precoated silica gel 60 F254 TLC plates using a mobile phase consisting of toluene, ethyl acetate, and methanol in an optimized ratio. The detection was performed densitometrically at an appropriate wavelength using CAMAG TLC Scanner. The method demonstrated excellent linearity over the concentration range of 100-600 ng/band for both drugs, with correlation coefficients (R2) exceeding 0.998. Validation was carried out in accordance with ICH Q2(R2) guidelines, covering parameters such as accuracy, precision, linearity, limit of detection (LOD), limit of quantification (LOQ), specificity, robustness, and ruggedness. The recovery values were found to be within acceptable limits, confirming the method's accuracy. The proposed HPTLC method can be effectively applied for routine quality control and analysis of Salbutamol and Etofylline in combined pharmaceutical formulations, offering advantages such as reduced solvent consumption, lower cost, and faster analysis time compared to conventional methods
An Effective and Time-Saving HPTLC Densitometry Technique for the Measuring of Antidiabetic Triple-Drug Combination: From TLC Spot Formation to Method Validation
No full textA precise, rapid, linear & robust High-Performance Thin-Layer Chromatography (HPTLC)-Densitometric was successfully developed and validated method for the simultaneous estimation of a triple antidiabetic drug combination comprising Metformin Hydrochloride (MET), Teneligliptin Hydrobromide Hydrate (TEN), and Pioglitazone Hydrochloride (PIO) in bulk and ph'ceutical formulation. Chromatographic separation was achieved using precoated silica gel 60 F254 TLC plates with a mobile phase made up of n-butanol, 1,4-dioxane, glacial acetic acid, and n-hexane in a ratio of 4:2:2:2 (%v/v/v/v). Densitometry was used for detection at 242 nanometers. Spots were obtained using distinct and well-resolved Rf values 0.20 ± 0.01, 0.55 ± 0.02, and 0.90 ± 0.01 for MET, TEN, and PIO, respectively. The ICH Q2 (R1) guidelines were followed in the validation of the approach, demonstrating excellent linearity over the ranges of concentrations of 1000-3500 nanogram/band for MET, 40-140 nanogram/band for TEN & 30-115 nanogram/band for PIO, with correlation coefficients (r2) of 0.9983, 0.9961, and 0.9965, respectively. The recovery studies confirmed the method's accuracy, yielding mean recoveries of 99.92% (MET), 100.03% (TEN) & 100.97% (PIO). The LOD and LOQ were determined to be 154.22 nanogram/band and 467.34 nanogram/band for MET, 8.66 nanogram/band and 26.25 nanogram/band for TEN, and 10.95 ng/spot and 33.18 ng/spot for PIO, respectivelyThe assay results further confirmed the reliability of the developed method, showing percentage recoveries of 99.03% (MET), 99.34% (TEN), and 99.03% (PIO). Overall, the proposed HPTLC-densitometric method provides a simple, economical and effective analytical tool for the routine quality control and simultaneous quantification of Metformin hydrochloride, Teneligliptin hydrobromide hydrate, and Pioglitazon
Sunflower achene hulling ability: impact of water availability and genetic
No full textThis study investigated the determinants of sunflower hulling ability by evaluating 30 commercial hybrids across eight environments over two years Variance analysis revealed that environmental factors explained 50% of the variability in hull extraction rate, while genetic factors accounted for 33%. Water availability during key developmental stages was critical: sufficient water during flowering promoted pericarp development and improved hulling, whereas non limiting water supply during grain filling reduced hulling ability, likely by increasing hull-kernel adhesion. The negative correlation between oil content and hullability (R = –0.44) was confirmed, reflecting a trade-off between oil accumulation and pericarp development. Thousand-seed weight and bulk density showed only weak associations with hullability. The model incorporating water requirement coverage during flowering and grain filling explained over 90% of the environmental effect on hullability. These findings highlight the strong environmental plasticity of hulling ability and the importance of avoiding water stress during the flowering period. While genetic improvement remains feasible, the phenotypic expression of hullability is highly sensitive to environmental conditions, particularly water availability during flowering and seed filling. This work provides a framework for breeding and agronomic strategies aimed at optimizing both seed quality and processing efficiency in sunflowers
A Study on the Utilization of Essential Oils as Gasoline Additive
No full textOne of the efforts to mitigate the negative impact of motor vehicles is to improve gasoline cleanliness through the addition of fuel additives. Essential oils and their derivatives have potential as additives to enhance fuel quality, as indicated by increased engine performance of efficiency, reduced fuel consumption, and lower emissions. This study evaluates the effectiveness of essential oil-based additives in improving gasoline cleanliness, combustion stability, emissions, and engine performance. The additives used in this research are a mixture of clove terpene and turpentine, added to gasoline at concentrations of 0.1% and 1% (%v/v). The results showed a reduction in water content by 19.98% - 27.5%, increased density by 0.3% - 0.78%, decreased particulate content by 41%, 40%, and 20%, RON value of 92, and sulfur content of 100 ppm. Essential oil additives reduce HC emissions at high engine speeds, decrease specific fuel consumption by 5.2%, and enhance combustion within the engine. However, they are not effective in reducing CO and CO2 emissions, nor do they significantly impact engine power output
Lensless Hypercentric Imaging using Digital Holography
No full textHypercentric imaging is a powerful imaging modality that allows for the inspection of a specimen and its sides in the same recording. Typically, hypercentric imaging involves special lens objectives, which are bulky and limit the use of interferometric methods. To overcome this, we introduce lensless hypercentric imaging utilizing digital holography. We show, that the same hologram can be used to render various digital image perspectives, depending on the size and the position of a virtual aperture. We describe the perspective imaging model in detail and present experimental results, which proof the main concept and exemplarily show the dependence of the image perspective from the position of the aperture. To the best of our knowledge, this is the first time that lensless hypercentric imaging was realized. The results combine the benefits of lensless digital holography with the hypercentric imaging modality, thereby opening a path to a new class of inspection systems
Utilization of Biodiesel-Water Emulsion as Fuel for Crumb Rubber Drying
No full textCrumb rubber is one of the main export commodities in Indonesia from the plantation sector. In the industrial scale, the process of crumb rubber drying generally still uses industrial diesel oil (IDO) as fuel. In order to participate in supporting the government's program for the development of renewable energy, especially biofuels to replace fossil fuels, many research has been conducted regarding the use of biodiesel-water emulsion (W/O) as an alternative fuel for crumb rubber drying. The biodiesel used is a mixture of 70% diesel oil and 30% FAME (B30-water) and a mixture of 60% diesel oil and 40% FAME (B40-water) from crude palm oil (CPO). The use of water as substituent agent for biodiesel is intended to increase fuel economy and minimize NOx and PM emissions which potential to decrease the rubber quality. A homogeneous and stable water biodiesel emulsion (90:10), namely B30-water and B40-water, was obtained by adding 5% emulsifier consisting of a mixture of Span 80 and Tween 80 as surfactants to form a B30-water and B40-water emulsion. Homogenization of biodiesel, water and surfactants mixture using a high-speed mixer (23,000 rpm) for 1-2 minutes resulting homogenous and stable B30-water and B40-water emulsions minimum 24 hours were then used as alternative fuel for crumb rubber drying by direct heating to the rubber surface at a drying temperature of 130-135 °C and drying air rate 1-1.5 m/sec. The results showed that B30-water and B40-water emulsions with a water content of 10% were appropriate to use as alternative fuels for crumb rubber drying. The quality of the dry crumb rubber produced was fulfill the requirement standard according to SNI 1903: 2017
Field efficacy assessment of a combination of afoxolaner, moxidectin and pyrantel pamoate to treat dogs naturally infested with
No full textCanine sarcoptic mange, caused by Sarcoptes scabiei, is a highly contagious and intensely pruritic skin disease in dogs. It is prevalent worldwide and has zoonotic potential. Therefore, effective treatment is important to safeguard animal welfare and public health. The present clinical field study aimed to confirm the efficacy of NexGard® Plus, an oral combination of afoxolaner, moxidectin and pyrantel pamoate, in treating dogs naturally infested with S. scabiei. It was a blinded, randomised, single-centre, negative-controlled efficacy study. Twenty naturally infested dogs were allocated into two groups: a group treated on Day 0 and Day 26/28 at the label dose, and an untreated control group. Skin scrapings were conducted similarly, once between Day −6 to 0, then on Days 26/28 and 56 for mite counts. Assessments of clinical signs were conducted at the same time intervals. In the treated group, mite infestations were reduced by 97% after the first treatment and were eliminated (100%) after the second treatment (p < 0.0005), while all dogs in the untreated control group remained infested for the whole study. Treated dogs had no pruritus, papules or crusts and clear evidence of hair regrowth by Day 56, unlike the dogs in the control group. This study demonstrated the elimination of S. scabiei mites and significant improvement of sarcoptic mange clinical signs in naturally infested dogs treated with the oral combination of afoxolaner, moxidectin and pyrantel
Characterization of Particleboard Form Sisal Using Citric Acid and Sucrose as Adhesive
No full textParticleboard is a primary option in automotive industry. Sisal, a natural fiber commonly used in producing industrial ropes, can potentially serve as an alternative raw material for particleboard manufacturing. It offers good mechanical strength, making it a suitable alternative for industrial applications. This research aimed to determine effect of ratio citric acid, sucrose on physical and mechanical properties of particleboard from sisal. The characterization of particleboard is determined based on JIS A 5908:2003. The data will be analyze using statistical one sample t-test. The results show that particleboard using sisal with an adhesive ratio of 15% citric acid and 85% sucrose has the best value. The physical and mechanical properties of this particleboard were a density of 0.55 g/cm3, a moisture content of 3.92%, a water absorption of 172.98%, a thickness swelling of 69.06%, an MOE of 7.44 N/mm2, and an MOR of 711 N/mm2. From this physical and mechanical properties, only density meet JIS A 5908:2003 standard. This result also showed that particleboard can’t be used for industry and needs to select the best methods like higher adhesive component