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Online sequential learning based on extreme learning machines for particulate matter forecasting
No full textsem informaçãoMicroscopically small solid particles and liquid droplets suspended in the air, known as particulate matter (PM), may significantly affect not only human health but also urban, natural and agricultural systems. Therefore, it is imperative to keep the conc169174sem informaçãosem informaçãosem informação6. Brazilian Conference on Intelligent System
Fog-assisted translation: towards efficient software emulation on heterogeneous IoT devices
No full textCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOWith predictions that in the near future tens of billions of devices will be added to the Internet of Things (IoT), new challenges arise, including the development and deployment of software for a wide variety of devices, architectures, instruction set ar12681277CAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOsem informaçãosem informação13/08293-732. IEEE International Parallel and Distributed Processing Symposium Workshop
A re-identification risk-based anonymization framework for data analytics platforms
No full textsem informaçãoPreserving individual privacy is one of the major issues in the context of Big Data, since handling huge volumes of data may contribute to the disclosure of sensitive or personally identifiable information. In fact, even when data is anonymized there is a101106sem informaçãosem informaçãosem informação14. European Dependable Computing Conferenc
Implementation of ISDB-Tb LDM broadcast system on SDR platform
No full textFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOThis paper aims to apply Layered Division Multiplexing (LDM) by Software Defined Radio (SDR) in the Brazilian Digital TV System (ISDB-Tb) for its evolution to the next generation Digital TV (DTV). It presents in detail the architecture of the transmitterFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO2016/06446-9IEEE Broadcast Symposiu
Analyzing railway capacity using a planning tool
No full textSem informaçãoRailway transportation is a mean of conveying ore, goods or passengers on wheeled vehicles running on rails. The operation is costly and the transported goods have low aggregated value, therefore profitability is enabled under long distances and large quaSem informaçãoSem informaçãoSem informaçãoJoint Rail Conferenc
Equity in the use of dental services provided by the Brazilian Unified Health System (SUS) among the elderly: a population-based study
No full textPropõe-se caracterizar os idosos usuários de serviços odontológicos ofertados pelo Sistema Único de Saúde, considerando o princípio da equidade. Trata-se de um estudo transversal analítico com modelagem hierarquizada, conduzido a partir de uma amostra probabilística, complexa, por conglomerados de idosos (65-74 anos) residentes em um município brasileiro de grande porte populacional. Foram incluídas variáveis independentes referentes a: características sociodemográficas, acesso a informações em saúde, comportamentos/sistema de atenção à saúde e desfechos em saúde. Realizou-se análises descritivas, bivariadas e múltiplas hierarquizadas. Dos 480 idosos incluídos, 138 (31,2%) utilizaram serviços odontológicos provenientes do SUS. O uso desses serviços foi maior à medida que diminuíam a renda per capita e a escolaridade dos idosos, menor entre os que não haviam realizado o autoexame da boca e maior entre os que usavam os serviços odontológicos para procedimentos que não fossem rotina. Além disso, verificou-se que utilizaram mais o SUS pessoas que tiveram o relacionamento afetado pela saúde bucal e uma autopercepção negativa da sua aparência. Conclui-se que o uso dos serviços odontológicos no SUS foi predominante entre os idosos que vivem sob condições de vulnerabilidade.211135093523CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE MINAS GERAIS - FAPEMIGSem informaçãoSem informaçãoThe scope of this study is to establish the profile of elderly users of dental services provided by the Brazilian Unified Health System(SUS) and associated factors from the standpoint of equity. It involves an analytical cross-sectional study with hierarchical modeling conducted on the basis of a complex probabilistic sample of groups of the elderly (65-74 years of age) living in a densely populated Brazilian city. Independent variables were included relating to: socio-demographic characteristics, access to information on health, behaviors/health-care system and health outcomes. Descriptive, bivariate and multiple hierarchical analysis was performed. Of the 480 elderly persons included, 138 (31.2%) used dental services from the SUS. Use of these services was greater as per capita income and level of schooling decreased. It was lower among those who had not conducted exams of their own mouths (oral self-examinations) and higher among those individuals who used dental services for non-routine procedures. In addition, people whose relationship had been affected by oral health issues and a negative perception of their appearance used the SUS more frequently. The conclusion drawn is that the use of dental services of the SUS was most prevalent among the elderly living in precarious conditions
The vegetative state and stem cells: therapeutic considerations
No full textThe vegetative state (VS), also known as “unresponsive wakefulness syndrome,” is considered one of the most devastating outcomes of acquired brain injury. While diagnosis of this condition is generally well-defined clinically, patients often appear to be awake despite an absence of behavioral signs of awareness, which to the family can be confusing, leading them to believe the loved one is aware of their surroundings. This inequality of agreement can be very distressing. Currently, no cure for the VS is available; as a result, patients may remain in this condition for the rest of their lives, which in some cases amount to decades. Recent advances in stem cell approaches for the treatment of other neurological conditions may now provide an opportunity to intervene in this syndrome. This mini review will address the development of VS, its diagnosis, affected cerebral structures, and the underlying basis of how stem cells can offer therapeutic promise that would take advantage of the often long-term features associated with this maladie to effect a repair of the severely damaged circuitry. In addition, current limitations of this treatment strategy, including a lack of animal models, few long-term clinical studies that might identify benefits of stem cell treatment, and the potential for development of tumors are considered7FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPnão temThe author’s laboratory is supported by the Canadian Institutes of Health Research and Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) in Brazi
The role of stand structure and palm abundance in predicting above-ground biomass at local scale in southern Amazonia
No full textMost work in Amazonia has concentrated on dense lowland evergreen rain forest, a vegetation type with >40% cover. Large parts of southern Amazonia are covered by open evergreen lowland rain forest, physiognomically dominated by high abundance of palms. This vegetation type has received relatively little attention so far. Understanding the key predictors of above-ground biomass (AGB) across scales is important to accurately quantify the impacts of land cover change on the terrestrial carbon budget. We assessed the structure of southern Amazonian forests, Brazil, to quantify the relative importance of variation in AGB caused by the abundance/density of palm species and by forest structure. We stratified the landscape into homogeneous units in terms of vegetation types and elevation for using as a guide for plot establishment. We used the variation partitioning technique to decompose the relative contribution of forest structure and palm abundance. The AGBcommunity (including trees, palms and lianas) and AGBtree (excluding palms and lianas) significantly decreased with increasing abundance of palms. The Attalea speciosa, a large-leaved palm species, was the most important for explaining the variance of AGB. The total variance of AGBtree was partially explained by a redundant effect of A. speciosa and trees (28%) and by trees alone (62%), based on models of basal area. The redundant effect, alongside with additional analyses, indicated (1) competition between A. speciosa and small trees and (2) covariation between A. speciosa and large trees. The abundance of palms plays a minor but significant role in predicting the AGB at the local scale in southern Amazonia94409420This work was supported by the David and Lucile Packard Foundatio
Copper transporter 1 affinity as a delivery strategy to improve the cytotoxic profile of rationally designed copper(II) complexes for cancer treatment
No full textCisplatin is widely used to treat different types of cancer, but its severe side effects are the major disadvantage of this treatment. Therefore, other metals are currently the subject of research in the rational development of anticancer drugs, such as copper, that has been demonstrated to be promising in this scenario. Here, we evaluated the effects of two novel copper complexes against breast cancer cell lines, and also examined the influence of overexpressing copper transporter 1 (CTR1) on the cytotoxicity of these complexes. Complex (1) [Cu(sdmx−)2(phen)] showed low IC50 values, induced intense cell morphological changes and arrested the cell cycle at the sub-G1 phase in cancer cells. Complex (1) was tested in transfected cells overexpressing the CTR1 receptor in order to compare its steric effects with a less bulky ligand and more labile complex (2) [CuCl2(impy)]. A significant reduction of IC50 value was observed in CTR1 overexpressing cells for complex (2) (32 μM to 20 μM) as compared to (1) (2.78 μM to 3.41 μM), evidencing a possible uptake through copper reduction (Cu+2 → Cu+1) mediated by CTR1. Thus, considering that CTR1 is a mediator of metallodrugs uptake, the development of strategies that use rational drug design is important in order to improve the therapeutic efficacy through greater specificity and consecutive reduction of side effects. Here we show the example for the case of copper(II) complexes67FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP2015/20882-3; 2017/19504-0; 2018/17170-0; 2013/07600-3; 2018/12062-
Correlation between office and home blood pressure in clinical practice: a comparison with 2017 American College of Cardiology/American Heart Association Hypertension Guidelines recommendations
No full textsem informação381179181CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ306154/2017-