Qazvin University of Medical Sciences
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بررسی اثر کوئرسیتین استریفیه شده با اسیدهای چرب امگا3 و امگا6 بر روی تکثیر، خواص مکانیکی و بیان ERK در رده سلولی A375 ملانوما
Get PDFSources of academic stress among Iranian adolescents: a multilevel study from Qazvin City, Iran
Get PDFBackground: Academic stress can cause mental and physical problems and affect adolescents’ healthy
development. This study aimed to estimate academic stress and explore its sources at the individual- and school
levels among school-going adolescents in the city of Qazvin, Iran.
Results: This cross-sectional study used a stratified cluster sampling to recruit 1724 students aged 12–19 years from
53 schools in Qazvin City. Data were collected using a validated self-administered questionnaire. The mean
academic stress score was 45.7 (95% CI 45.2, 46.3). The stress level was statistically higher among older 47.5 (95% CI
46.7, 48.3) than younger 44.1 (95% CI 43.4, 44.9) adolescents. The main academic stressors included: future
uncertainty 69.7 (95% CI 68.8, 70.7), academic competition 58.5 (95% CI 57.3, 59.6), and interaction with teachers
56.1 (95% CI 55.3, 56.9). Gender, educational period, school type, family socioeconomic status, and father’s
education were associated with academic stress.
Conclusions: We conducted a multilevel study using a random sample of male and female students in the city of
Qazvin, Iran. Results indicated moderate levels of stress among Iranian adolescents. The academic stress was
associated with several individual and school-level variables. Students and their families and teachers need
education on stress prevention methods and coping mechanisms. Future research should focus on developing and
testing multilevel policies and interventions to improve students’ mental health and academic performance.
Keywords: Academic stress, Adolescence, Students, Multilevel analysis, Ira
آنالیز شغلی و شناسایی وظایف موثر درانتقال کووید-19 در مورد مرگ کارمند شاغل در بیمارستان شفا تاکستان استان قزوین(چکیده طرح تحقیقاتی)
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مقایسه سطح بیلی روبین توتال بند ناف با بیلی روبین روز سوم تولد در نوزادان ترم در بیمارستان کوثر قزوین
No full textEffects of the Esterified Quercetin with omega3 and omega6 fatty acids on cell viability and BAX and BCL-2 gene expression in MCF-7 Human Breast Cancer Cell Line.
Get PDFEffects of propolis supplementation on glycemic status, lipid profiles, inflammation and oxidative stress, liver enzymes, and body weight: a systematic review and meta-analysis of randomized controlled clinical trials
Get PDFThe aim of meta-analysis was to assess the effects of propolis on markers of oxidative stress, lipid profiles, inflammation and
glycemic control, liver enzymes, and weight control. The heterogeneity between the included studies was indicated using the
Cochrane’s Q test and I-square (I2
) statistic. 14 trials were included in this meta-analysis. Our meta-analysis indicated a significant reduction in fating glucose (WMD: -17.00; 95% CI: −30.88, −3.11), HbA1C (WMD: -0.42; 95% CI: −0.75, −0.10), and
insulin (WMD: -1.75; 95% CI: −3.24, −0.26) and a marginally significant reduction in insulin resistance (WMD: -0.60; 95% CI:
−1.20, 0.00) following propolis supplementation in 10, 8, 6, and 5 studies, respectively. Pooling 5 effect sizes, a significant
reduction was seen in ALT (WMD: -5.63; 95% CI: −10.59, −0.67) and aspartate aminotransferase (AST) (WMD: -3.09; 95% CI:
−5.15, −1.03) following propolis. A significant beneficial effect was observed for CRP (WMD: -1.11; 95% CI: −1.92, −0.29),
TNF-α (WMD: -6.71; 95% CI: −9.44, −3.98) and interleukin-6 (IL-6) (WMD: -17.99; 95% CI: −35.56, −0.42) concentrations
after propolis supplementation. This study demonstrated the beneficial effects of propolis on FPG, HbA1c, insulin, CRP, TNF-α
and liver enzymes levels
Prevalence of G6PD deficiency in Iranian neonates with jaundice: a systematic review and meta-analysis
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Comprehensive genotype-phenotype correlation in AP-4 deficiency syndrome; Adding data from a large cohort of Iranian patients
Get PDFMutations in adaptor protein complex-4 (AP-4) genes have first been identified in
2009, causing a phenotype termed as AP-4 deficiency syndrome. Since then several
patients with overlapping phenotypes, comprised of intellectual disability (ID) and
spastic tetraplegia have been reported. To delineate the genotype-phenotype correlation of the AP-4 deficiency syndrome, we add the data from 30 affected individuals
from 12 out of 640 Iranian families with ID in whom we detected disease-causing
variants in AP-4 complex subunits, using next-generation sequencing. Furthermore,
by comparing genotype-phenotype findings of those affected individuals with previously reported patients, we further refine the genotype-phenotype correlation in this
syndrome. The most frequent reported clinical findings in the 101 cases consist of ID
and/or global developmental delay (97%), speech disorders (92.1%), inability to walk
(90.1%), spasticity (77.2%), and microcephaly (75.2%). Spastic tetraplegia has been
reported in 72.3% of the investigated patients. The major brain imaging findings are
abnormal corpus callosum morphology (63.4%) followed by ventriculomegaly
(44.5%). Our result might suggest the AP-4 deficiency syndrome as a major differential diagnostic for unknown hereditary neurodegenerative disorders