Qazvin University of Medical Sciences
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ارتباط ویژگی های شخصیتی پرستاران با رفتار های ایمن آنان در بیمارستان های شهر قزوین طی سال های 99-1398(چکیده طرح تحقیقاتی)
بررسی اثر مکمل الایژیک اسید بر مقاومت انسولینی، وضعیت استرس اکسیداتیو، فاکتورهای التهابی و سطح هورمون های جنسی در زنان مبتلا به سندروم تخمدان پلی کیستیک (چکیده طرح تحقیقانی)
ارزیابی آمادگی بیمارستان های شهر اهواز در جذب گردشگران سلامت: رویکرداستانداردهای کمیسیون مشترک بین الملل JCI (فایل ارائه دفاع نهایی)
The effect of training based on the health belief model on self-care behaviors of women with high blood pressure during pregnancy
Background and Purpose: High blood pressure in pregnancy is the main cause of many maternal and fetal complications and deaths, as well as one of the three main causes of maternal deaths worldwide after hemorrhage and sepsis. Therefore, proper management and control of high blood pressure in pregnancy is considered as an important key factor, and performing self-care behaviors is one of the most important strategies to control blood pressure and maintain it at a normal level. This study was conducted with the aim of investigating the effect of education based on the health belief model on the self-care behaviors of women with high blood pressure during pregnancy
materials and ways: This study was a two-group randomized controlled trial (intervention and control) that was conducted on 90 women with high blood pressure during pregnancy who referred to Al-Zahra Hospital in Rasht in 2019-2020. Data collection tools included demographic and midwifery questionnaires, researcher-made questionnaires on health belief model and self-care behaviors in high blood pressure during pregnancy. The educational intervention took place during 3 sessions of 90 minutes. Information was collected by completing questionnaires during direct interviews before the educational intervention and one month after. Finally, the data were analyzed using spss25 software and descriptive statistical methods (including frequency, mean, and standard deviation) and inferential statistics including t-test, paired t, chi-score, Ancova, and Cohen's effect.
Findings: It showed that the average scores of awareness and perceived constructs of the health belief model and self-care behaviors in high blood pressure in pregnancy before and after the intervention show a significant difference (p-value < 0.001) and in other words, training based on the model Health belief has increased awareness, perceived sensitivity, perceived severity, perceived benefits, action guidelines, self-efficacy and self-care behaviors in the test group compared to the control group, and the mean score of perceived barriers has also decreased in the test group, and these differences from The opinion of Cohen's work has been very large
Conclusion: Education based on HBM increased self-care behaviors in mothers with high blood pressure during pregnancy through increasing awareness and perceived constructs of the health belief model. Therefore, it is recommended to use education based on the health belief model in order to increase self-care behaviors and proper control of high blood pressure in pregnancy
Keywords: Health belief pattern, self-care behaviors, high blood pressure in pregnanc
Magnetic Hyperthermia as an adjuvant cancer therapy in combination with radiotherapy versus radiotherapy alone for recurrent/progressive glioblastoma: a systematic review
Abstract
Introduction Hyperthermia therapy (HT) is a recognized treatment modality, that can sensitize tumors to the effects of
radiotherapy (RT) and chemotherapy by heating up tumor cells to 40–45 °C. The advantages of noninvasive inductive magnetic
hyperthermia (MH) over RT or chemotherapy in the treatment of recurrent/progressive glioma have been confirmed
by several clinical trials. Thus, here we have conducted a systematic review to provide a concise, albeit brief, account of the
currently available literature regarding this topic.
Methods Five databases, PubMed/Medline, Embace, Ovid, WOS, and Scopus, were investigated to identify clinical studies
comparing overall survival (OS) following RT/chemotherapy versus RT/chemotherapy + MH.
Results Eleven articles were selected for this systematic review, including reports on 227 glioma patients who met the study
inclusion criteria. The papers included in this review comprised nine pilot clinical trials, one non-randomized clinical trial,
and one retrospective investigation. As the clinical trials suggested, MH improved OS in primary glioblastoma (GBM),
however, in the case of recurrent glioblastoma, no significant change in OS was reported. All 11 studies ascertained that no
major side effects were observed during MH therapy.
Conclusion Our systematic review indicates that MH therapy as an adjuvant for RT could result in improved survival, compared
to the therapeutic outcomes achieved with RT alone in GBM, especially by intratumoral injection of magnetic nanoparticles.
However, heterogeneity in the methodology of the most well-known studies, and differences in the study design
may significantly limit the extent to which conclusions can be drawn. Thus, further investigations are required to shed more
light on the efficacy of MH therapy as an adjuvant treatment modality in GBM.
Keywords Magnetic hyperthermia · Glioma · Clinical Trial · Overall survival · Systematic Revie