Qazvin University of Medical Sciences
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"ارزیابي مقایسه ای میزان برداشت اسمیر لایر با محلول های چیتوزان واتیلن دی آمین تترا استیک اسید با استفاده از تكنیک فعال سازی XP endo finisher"
Comparing immunogenicity of VZV gE antigen in mRNA, subunit and attenuated vaccine in primates(ارائه ژورنال کلاب)
Differential Anti-Proliferative and Anti-Migratory Activities of Ursolic Acid 3-O-Acetylursolic Acid and Their Combination Treatments with Quercetin on Melanoma Cells(ارائه ژورنال کلاب)
Theragnostic Glycol Chitosan-Conjugated Gold Nanoparticles for Photoacoustic Imaging of Regional Lymph Nodes and Delivering Tumor Antigen to Lymph Nodes(ارائه ژورنال کلاب)
Sleep duration and its relationship with school performance in Iranian adolescents
Background. Inadequate or poor sleep quality is common problems in adolescent that affect on their learning, memory and
school performance. The present study aimed to determine the
association between sleep hours and academic performance in
young adults.
Methods .This cross-sectional study was designed as a descriptive-
analytic study. Samples of adolescents of 14-18 years old
in Qazvin city were enrolled. The Pediatric sleep questionnaire
and BEARS questionnaire used for all students to screen comprehensively
major sleeps problems in them. Chi-square test, t-test,
analysis of variance (ANOVA), and correlation were performed to
determine the relationship between the data (P < 0.001).
Results. Between 653 adolescents, 40% were male and 60% were
female. Sleep duration, sleep onset delay, sleep insufficient, rate
of oversleeping and academic performance had a direct relationship
with gender (P < 0.001). The sleep duration, rate of oversleeping
and academic performance were significantly higher in
boys, sleep onset delay and sleep insufficient was significantly
higher in girls. Time of falling sleep at weekend nights and weekday
nights have positively correlation with age (P < 0.001). Also,
a significant relationship between students’ sleep hours with academic
performance was shown (P < 0.001).
Conclusions. The overall result was that sleep duration, sleep
onset delay, sleep insufficient and rate of oversleeping of students
in this study had a significant influence on academic performance.
Students without difficulty in falling asleep had good
academic performance in compared to students with difficulty in
falling asleep
The effect of risperidone and electroconvulsive therapy on corrected QT interval in electrocardiogram of psychiatric patients
BACKGROUND: Some types of antidepressants and antipsychotic medications have cardiovascular side effects that can be life-threatening. Electroconvulsive therapy (ECT) is capable of generating physiological stress and may lead to increased QT interval followed by arrhythmias. Risperidone can also increase the risk of arrhythmia by increasing the corrected QT (QTc) interval. Since many patients require co-administration of risperidone and ECT, this study aimed to investigate the concurrent effect of ECT and risperidone administration on the QTc interval.
METHODS: For this cross-sectional study, 60 patients (18-65 years) admitted in 22 Bahman Psychiatric Hospital (Qazvin, Iran) that were candidate for treatment with risperidone, ECT, or both methods were concurrently divided into three groups. The groups included patients treated with ECT, risperidone, and combination treatment (risperidone and ECT). At the beginning of the study, electrocardiogram (ECG) was obtained for all patients and QT was performed manually, and finally, QTc interval was measured two times for each group. Required information was collected through medical records. Then, inferential statistics, analysis of variance (ANOVA), was used to determine differences between different variables.
RESULTS: A significant increase in heart rate (HR) in the third group compared to first and second groups was observed. None of the treatments had a significant effect on QTc interval, but the QTc interval increased slightly in groups treated with the ECT alone and particularly, the ECT plus risperidone in comparison to the baseline values.
CONCLUSION: Our study showed that risperidone, ECT, and their concomitant combination did not affect the QTc interval. Therefore, risperidone and ECT are safe and their combination can also be a good option for refractory patients undergoing ECG monitoring and cardiopulmonary devices.
Keywords: Antipsychotic; Arrhythmia; Electroconvulsive Therapy; QTc Interval; Risperidon
Investigation of Antibiotic Resistance Pattern in Isolated From Urine and Blood Samples of Patients Admitted To the Intensive
Background and objectives: Antibiotic resistance is a global health challenge that affects both individuals and the health system in many ways. The aim of this study was to evaluate the antibiotic resistance pattern in isolates from patients admitted to the intensive care unit (ICU) of a hospital in Qazvin, Iran.
Methods: This descriptive and retrospective study was performed on urine and blood samples collected from 1318 ICU patients in the Velayat Hospital of Qazvin (Iran) during 2017-2019. Data were collected from patients’ medical records. All statistical analyses were performed using SPSS software (version 25).
Results: Based on the findings, 65.2% of the samples were related to urinary tract infections and 34.7% to bloodstream infections. Escherichia coli (68.6%) and Stenotrophomonas (41.0%) were the most common bacteria isolated from urinary tract infections and bloodstream infections, respectively. Moreover, the rate of antibiotic resistance was higher among Acinetobacter, Escherichia coli, Stenotrophomonas, Enterococcus and Pseudomonas isolates.
Conclusion: The rate of drug resistance in isolates from ICU patients is alarmingly high and requires immediate attention. It is recommended to modify antibiotic prescriptions in the hospital based on the results of antibiotic resistance pattern, particularly for treatment of infections caused by E. coli and Stenotrophomonas.
Keywords: Drug resistance, Intensive care units, Hospitals