Qazvin University of Medical Sciences

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    Predictors of Quality of Life in Patients with Heart Disease

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    Individuals with heart disease have been found to have more negative psychological and physical effects that impact their quality of life (QoL) than the general population. Spiritual well-being is considered a protective factor associated with QoL in people with heart disease. Therefore, the current research seeks to evaluate whether sociodemographic factors and spiritual well-being predict QoL among patients with heart disease. A total of 500 patients who were selected through a convenient sampling method from an Iranian hospital participated in this descriptive-correlational study. Data were collected using the McGill QoL Questionnaire, the Spiritual Wellbeing Scale, and demographic variables. The data analysis included descriptive and inferential statistics powered by SPSS (v. 23). Following multivariate analyses, findings revealed that those participants with their main source of income derived from family or a government pension and with College or intermediate educational levels were more likely to have higher QoL. Those participants with average or poor socioeconomic status reported higher QoL than those who were more affluent. Furthermore, younger patients (− 0.2, 95% CI − 0.3 to − 0.003, p = 0.016) and those with higher social support (0.7, 95% CI 0.2 to 1.3, p = 0.006) and spiritual well-being (0.2, 95% CI 0.1 to 0.3, p < 0.001) had significantly better QoL. In the current study, spiritual well-being and social support led to reduced negative psychological sequelae and improved QoL in cardiac patient

    Pathological Variants of Aminoacyl-tRNA-synthetase-Interacting Multifunctional Protein 1 Gene in an Iranian Consanguineous Family With Autosomal Recessive Intellectual Disability

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    Background Intellectual disability (ID) is one of the most common neurodevelopment disorders that caused by both environment and genetic factors. Genetic diseases account for 50% of ID incidents and have important role in its development. One of the most important risk factors of ID in most countries is consanguineous marriage. In consanguineous families, the risk of developing autosomal recessive ID is 3.6-fold higher. There is high prevalence of consanguineous marriage in Iran (about 40 %). Objective In this study, we aimed to investigate the pathological variants of aminoacyl-trna-synthetaseinteracting multifunctional protein 1 (AIMP1) in an Iranian consanguineous family with multiple-ID affected members. Methods this analytical epidemiological study, whole exome sequencing method was used to examine the molecular etiology in two female ID patients of a consanguineous family living in Qazvin, Iran. Sanger sequencing was carried out for validating potential causative variants in patients, and co-segregation analysis for other family members. Findings A stop-gain variant (p. Arg158*) in the AIMP1 gene was identified as pathological variant in the study family according to American College of Medical Genetics and Genomics guidelines. Conclusion The found variant in the AIMP1 gene caused truncated protein and clinical manifestations such as developmental delay, ID, spastic paraplegia, thin corpus callosum, and speech impairment in the two patients

    Psychometric Testing of Three COVID-19-Related Scales Among People with Mental Illness

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    Fear of novel coronavirus 2019 (COVID-19) may result in psychological health problems among different populations. Moreover, believing COVID-19 information and preventive COVID-19 infection behaviors are relevant constructs associated with fear of COVID-19. Therefore,thepresent studyvalidatedthreeinstrumentsassessingfear,beliefs,andpreventive behaviors related to COVID-19 among individuals with mental illness. Moreover, relationships between the three constructs were examined. Individuals with mental illness (N=400; 178 females; mean age=46.91 years) completed the Fear of COVID-19 Scale (FCV-19S), Believing COVID-19 Information Scale (BCIS), Preventive COVID-19 Infection Behaviors Scale (PCIBS), and Depression Anxiety Stress Scale-21 (DASS-21). The FCV-19S, BCIS, and PCIBS demonstrated a single-factor structure with satisfactory fit indices. MoreoverbelievingCOVID-19informationpositivelyandsignificantlyassociatedwithfearofCOVID19, and fear of COVID-19 negatively and significantly associated with preventive behaviors and positively and significantly associated with psychological distress. The FCV-19S, BCIS, and PCIBS may assist healthcare providers in assessing COVID-19-related information among individuals with mental illness. Consequently, relevant programs may be designed to help individuals with mental illness going through the period of crisis

    Predictors of Quality of Life in Patients with Heart Disease

    Get PDF
    Individuals with heart disease have been found to have more negative psychological and physical effects that impact their quality of life (QoL) than the general population. Spiritual well-being is considered a protective factor associated with QoL in people with heart disease. Therefore, the current research seeks to evaluate whether sociodemographic factors and spiritual well-being predict QoL among patients with heart disease. A total of 500 patients who were selected through a convenient sampling method from an Iranian hospital participated in this descriptive-correlational study. Data were collected using the McGill QoL Questionnaire, the Spiritual Wellbeing Scale, and demographic variables. The data analysis included descriptive and inferential statistics powered by SPSS (v. 23). Following multivariate analyses, findings revealed that those participants with their main source of income derived from family or a government pension and with College or intermediate educational levels were more likely to have higher QoL. Those participants with average or poor socioeconomic status reported higher QoL than those who were more affluent. Furthermore, younger patients (− 0.2, 95% CI − 0.3 to − 0.003, p = 0.016) and those with higher social support (0.7, 95% CI 0.2 to 1.3, p = 0.006) and spiritual well-being (0.2, 95% CI 0.1 to 0.3, p < 0.001) had significantly better QoL. In the current study, spiritual well-being and social support led to reduced negative psychological sequelae and improved QoL in cardiac patient

    A theory-based intervention to promote medication adherence in patients with rheumatoid arthritis: A randomized controlled trial

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    Introduction/objectives Adherence to prescribed medication regimens is fundamental to the improvement and maintenance of thehealthofpatientswithrheumatoidarthritis.Itisthereforeimportantthatinterventionsaredevelopedtoaddressthisimportant health behavior issue. The aim of the present study was to design and evaluate a theory-based intervention to improve the medication adherence (primary outcome) among rheumatoid arthritis patients. Methods The study adopted a pre-registered randomized controlled trial design. Rheumatoid arthritis patients were recruited from two University teaching hospitals in Qazvin, Iran from June 2018 to May 2019 and randomly assigned to either an interventiongroup(n=100)oratreatment-as-usualgroup(n=100).Theinterventiongroupreceivedatheory-basedintervention designed based on the theoretical underpinnings of the health action process approach (HAPA). More specifically, action planning (making detailed plans to follow medication regimen), coping planning (constructing plans to overcome potential obstacles that may arise in medication adherence), and self-monitoring (using a calendar to record medication adherence) of the HAPA has been used for the treatment. The treatment-as-usual group received standard care. Results Dataanalysiswasconductedbasedontheprincipleofintentiontotreat.Usingalinearmixed-effectsmodel(adjustedfor age, sex, medication prescribed, and body mass index), the results showed improved medication adherence scores in the intervention group (loss to follow-up=16) compared to the treatment-as-usual group (loss to follow-up=12) at the 3-month (coefficient=3.9; SE=0.8) and 6-month (coefficient=4.5; SE=0.8) follow-up. Intervention effects on medication adherenc

    The effect of education intervention based on the theory of planned behavior on the intention of third-level driving license applicants to observe safe driving behaviors

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    Abstract Background and Purpose: Road accidents are one of the leading causes of death and disability in the world. The aim of this study was to determine the effect of educational intervention based on the theory of planned behavior Observing safe driving behaviors in applicants for licenses in Khorramdarreh city of Zanjan province. Materials and methods: The present study was an experimental study which is from April 2020 to Aug 2020 It was performed in Khorramdarreh city of Zanjan province. 100 applicants for driver's license using random sampling method in the form of experimental and control groups participated in the study. Training program in three months included six Groups discussion session in groups Five to seven of people For Forty-five to sixty minutes and three times face-to-face training session For fifteen minutes with the focus on identifying high-risk driving behaviors. The importance of observing safe behaviors, positive and negative consequences, external and mental barriers was observing safe behaviors. Research tools demographic characteristics questionnaire and scale for measuring the structures of planning behavior theory. chi-square, independent and paired t-tests and analysis of covariance were used to analyze the data. Results: The mean age of participants was 30.61±6.55 years. Before the educational intervention between the two experimental groups And there was no significant difference in control in terms of TPB -related structures But after training, the results showed analysis of covariance applicants' attitude score (from 16.40±4.22 to 29.60±3.36 , P <0.05), Abstract norms score (from 10.08±2.85 to 15.52 ± 2.06 ,P <0/05), Perceived behavioral control score (from 15.30±1.97 to 21.24±2.50 ,P <0.05), And intention score (from 18.68±6.90 to 35.68±5.51 ,P <0.05), In the applicants for driving licenses, the participants in the experimental group significantly improved. Discussion: Application of the theory of programmed behavior can be effective in training drivers to observe safe behavior and in designing educational interventions, emphasis should be placed on model constructs or the same psychological antecedents related to safe driving behavior. Keywords: Attitude, safety, Driving, Accident, Health education, Self-efficac

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