Qazvin University of Medical Sciences

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    10283 research outputs found

    Psychometric Properties of the Persian Generalized Trust Scale: Confirmatory Factor Analysis and Rasch Models and Relationship with Quality of Life, Happiness, and Depression

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    The psychometric properties of the Generalized Trust Scale (GTS) are well established. Furthermore,previousstudieshavefoundthattheGTSispositivelyassociatedwithbetter mental health and lower distress, and the literature finds that trust is good for mental health. However, current literature does not have any psychometric evidence concerning the Persian GTS. This study translated the GTS into Persian and validated its psychometric properties. After translating the GTS into Persian using robust and standardized translation procedure, 1200 Iranians (mean age=34.83 years; 583 [48.6%] males) completed the GTS, along with the Hospital Anxiety and Depression Scale (HADS), Short Form-12 (SF-12), and Oxford Happiness Questionnaire Short Form (OHQ-SF). The factor structure of Persian GTS was confirmed by a unidimensional model with a method factor (comparative fit index=0.998; Tucker-Lewis index=0.992). The unidimensional model was also supported by Rasch analysis (mean square=0.75 to 1.31). Other properties of the Persian GTS were satisfactory. More specifically, test-retest reliability was good (intraclass correlational coefficient=0.865), internal consistency was good (α=0.881), and concurrent validity was supported (standardized β=−0.086 with depression in the HADS [p=0.045];=−0.162 with anxiety in the HADS [p<0.001];= 0.077 with mental component score in the SF-12 [p=0.044]; =0.624 with OHQ-SF [p<0.001]).Thesix-itemPersianGTShas promisingpsychometricpropertiesand can be an effective measure to assess trust among Iranians

    The branding process for healthcare centers: Operational strategies from consumer’s identification to market development

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    Medicalcentersneedbrandingapproachtoimprovetheirpositioninpatients’minds.Thisstudy wascarriedoutusingmixedmethod.Theparticipantsincludedmainexperts,hospitalmanagers and headquarters of the Ministry of Health. The data collection tool was a semi-structured interview and a researcher-made questionnaire. Branding process was conceptualized in 5steps, including Market Identification, Brand Identity, Brand Positioning, Development and Consolidation Strategy. All path coefficients were defined in the range. The results of the indices showed that the fit was good and the final model was valid. The activities of Medical centers should be based on the identification of the target market. Unique services with new knowledge and equipment and experienced clinical staff to meet patients’ needs with appropriate price and quality have to be provided

    TheEffectofUsingOliveOilandFishOilProphylactic Dressings on Heel Pressure Injury Development in Critically Ill Patients

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    Introduction and Aim: Prevention of pressure injuries in patients hospitalized in intensive care units is significantly important. Therefore, in the present study, the effect of using olive oil and fish oil prophylactic dressings on the development of heel pressure injuries was investigated. Methods: The present study was a clinical trial conducted in the intensive care unit of Shahid Beheshti Hospital, in Yasuj. Fifty patients, who were at moderate to high risk of pressure injuries development, were randomly divided into two groups based on the mean score of the Braden scale. In one group, patients’ heels were dressed using olive oil prophylactic dressing, and in the other group, patients’ heels were dressed using fish oil prophylactic dressing. The dressings were changed 3 times a day. Collected data were then analyzed using SPSS v16. Results: No significant difference was determined in demographic variables among the two groups (p<0.05). In terms of the development of heel pressure injuries, none of the patients in the olive oil and fish oil groups had pressure injuries. Conclusion: Therewerenostatisticallysignificantdifferencesineithertreatmentgrouprelated to heel pressure injuries outcomes during the 7 days observed in the study. Additionally, both dressings had the same effects. Further studies are recommended in this regard

    فایل آموزشی کارگاه اسکولار

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    Comparison of the effects of sertraline and L-carnitine on intradialytic hypotension; a double blind clinical trial

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    Introduction: Although some studies have reported the positive effect of sertraline and L-carnitine on intradialytic hypotension (IDH), a common complication of dialysis, however the results are controversial. Objectives: The aim of this study was to compare the effects of sertraline and L-carnitine on blood pressure in patients with chronic renal failure who were undergoing dialysis. Patients and Methods: This double-blind clinical trial was conducted on 32 hemodialysis patients who suffered from IDH in more than 50% of dialysis sessions. Patients were randomly divided into two groups of sertraline (50 mg daily) and L-carnitine (1000 mg daily), with 16 patients in each group. Duration of treatment was four weeks, then patients were followed up for additional three weeks. The changes in patients’ blood pressure were monitored in each group and the results compared between the two groups. Results: Of all, 18 patients (56%) were female, 14 patients (44%) were male, and their mean (SD) age was 60±15 years. At the end of the study, mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP), and mean arterial pressure (MAP) were significantly increased in both the sertraline and L-carnitine groups (P<0.05). In addition, nadir SBP, nadir DBP, and nadir MAP in each group were significantly increased compared to pre-treatment period (P<0.001). An increase of more than 5 mm Hg in SBP, DPB, and MAP was observed in half of the subjects in the sertraline group and more than two-thirds of the patients in the L-carnitine group, however there was no significant difference between the two groups (P>0.05). Conclusion: The findings of this study showed that the administration of sertraline or L-carnitine for one month could significantly increase SBP, DBP, MAP, and nadir blood pressures in dialysis patients suffering from IDH during dialysis sessions because there was no significant difference between the two drug

    Synthesis of immobilised Ni-doped TiO2 nanoparticles through hydrothermal route and their efficiency evaluation in photodegradation of formaldehyde

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    The aim of the present study was to synthesis Ni-doped TiO2 nanoparticles (NPs) in order to evaluate their effectiveness in photocatalytic degradation of formaldehyde in the aqueous phase. The Ni-doped TiO2 NPs were synthesised using a mild hydrothermal method. They were then immobilized on glass plates by the calcination method. Characterisation of Ni-doped TiO2 NPs was also carried out using scanning electron microscopy (SEM) and X-ray diffraction (XRD) analyses. The SEM images showed the uniform distribution of assynthesised NPs on the surface of glass plates, with multidimensional crystalline structures. The results indicated that increasing the dopant weight ratio to 0.7% enhanced the photocatalytic degradation efficiency of formaldehyde; however, a further increase in the dopant weight ratio reduced the process efficacy. According to the results, increasing the initial pH from acidic and neutral to alkaline conditions decreased the efficacy of the process. Furthermore, the results showed that increasing the amount of nanocatalyst and decreasing the initial concentration of formaldehyde favoured the photocatalytic degradation of formaldehyde

    Antimicrobial peptides-loaded smart chitosan hydrogel: Release behavior and antibacterial potential against antibiotic resistant clinical isolates

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    In this study, we synthesized thermo -responsive chitosan (TCTS) hydrogels, and loaded with different concentrations of antimicrobial peptide (AMP) (0, 4, 8 and 16 µg.ml - 1 ) to fabricate an antibacterial wound dressing against resistant clinical isolates. Physico -chemical properties, release behavior, cytobiocompatibility and antibacterial activity of the AMP -TCTS hydrogels against standard strain and resistant Acinetobacter baumannii were fully determined in vitro. The TCTS -40% β -glycerolphosphate hydrogels showed a gelation time of 15 min at 37 °C. 80% weight loss at day 35 with no changes in pH value was observed. AMP -TCTS hydrogels showed a burst release of AMP (around 40%) at day 1, and a controlled release up to day 7. A dramatic water uptake was observed at first 4 h, and then continued for 10 h in a steady manner. All the AMP -TCTS hydrogels showed excellent cytobiocompatibility for human fibroblasts. The TCTS showed no antibacterial activity against both standard strain and clinical isolates. All the AMP - TCTS hydrogels had strong antibacterial activity against standard strains, but only 16 µg.ml - 1 showed antibacterial behavior against resistant A. baumannii . Our results strongly suggest the 16 µg.ml - 1 AMP -TCTS hydrogel as a n excellent antibacterial wound dressing against resistant A. baumannii , and now promises to proceed with pre -clinical investigations

    Evidence for hyperprolactinemia in migraineurs: a systematic review and meta-analysis

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    Background One of the hypothalamus-pituitary axis hormones which may play a crucial role in pathophysiology of migraine is prolactin which is secreted from anterior pituitary gland and synthesized by various immune system cells as well. Whether prolactin blood levels can affect the migraine pathogenesis is an open question. Therefore, investigating prolactin circulatory levels in migraineurs may pave the way to underpin the mechanisms of migraine pathophysiology at biochemical levels. In the current investigation, the prolactin blood levels in the migraine subjects were investigated using systematic review and metaanalysis. Methods Using online and specialized biomedical databases including Google Scholar, Medline, Pubmed, Pubmed Central, Embase, and Scopus, without the beginning date restriction until Feb 2019, the systematic review retrieved 11 publications in this systematic review after fulfilling for the inclusion and exclusion criteria. For heterogeneity, extent calculation statistical testing was applied. In the present study, the levels of circulatory prolactin in migraineurs assessed using standardized mean difference (SMD) as the effect size. Results Q quantity and I 2 % statistic index showed a high heterogeneity in the 13 selected publications (188.370 and 92.568, respectively) and random-effects model was chosen for further analyses. The meta-analysis on a total number of 460 migraineurs and 429 healthy controls found that the weighted pooled SMD for the effects of prolactin blood concentrations on migraine pathogenesis was as follows: SMD = 1.435 (95% confidence interval, 0.854–2.015). Conclusion The current investigation presents evidence that prolactin blood levels are higher in migraineurs than healthy subjects

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