Qazvin University of Medical Sciences
Qazvin University of Medical Sciences RepositoryNot a member yet
10283 research outputs found
Sort by
Predicting psychological factors affecting regular physical activity in hypertensive patients: Application of health action process approach model
Get PDFAim: The aim of this study was to determine the factors affecting the behaviour of
regular physical activity in patients with hypertension using the health action process
approach (HAPA) model.
Design: This cross-sectional study was conducted on 176 hypertension patients, in
Astaneh-e-Ashrafiyeh, Guilan, Iran, 2018–2019.
Methods: Data collection tools included demographic characteristics, medical history,
the short form of International Physical Activity Questionnaire (IPAQ) and
scales related to the HAPA model. The data were analysed using chi-square, independent
t test, one-way ANOVA, Pearson's correlation coefficient and path analysis
on AMOS, version 23.0.
Results: Action self-efficacy (β = 0.59), outcome expectancy (β = 0.20) and risk perception
(β = 0.18) had a statistically significant effect on intention. Moreover, the
path coefficient between intention (β = 0.35) and coping self-efficacy (β = 0.29) with
physical activity was statistically significant. The results revealed that HAPA constructs
were able to describe 45% of the variance in intention and 31% of the variance
in physical activity behaviour.
Conclusion: The HAPA model is a useful framework for describing the factors affecting
physical activity in hypertension patients
The Effectiveness of Group Cognitive‑Behavioral Therapy on General Self‑Efficacy, Self‑Control, and Internet Addiction Prevalence among Medical University Students
Get PDFIntroduction: Various studies have highlighted the high prevalence of psychological and psychiatric problems among students with Internet addiction (IA). This study aimed to determine the effect of GCBT on self-control, self-efficacy as well as the prevalence of IA amongst students of Qazvin University of
Medical Sciences (QUMS). Methods: This randomized controlled trial was performed on 80 students addicted to the Internet. Participants were randomly divided into control (without intervention) and treatment group (GCBT). The experimental group participated in a GCBT program consisted of 10 two2-hour sessions based on psychosocial training, cognitive reconstruction, behavior modification, and improving emotion regulation. Data were collected using demographic information, Yang IA test, brief self-control scale, and compulsive iInternet usage scale before and 3 months after GCBT. Results: The Rfindings demonstrated significant improvements in general self-efficacy (21.90 ± 5.1-–27.31 ± 3.9, F = 46.131, df = 1, P < 0.001) and self-control (33.03 ± 4.7-–44.78 ± 6.1, F = 59.252, df = 1, P < 0.001), while compulsive Internet usage (41.41 ± 6.35-–25.13 ± 3.97, F = 163.359, df = 1, P < 0.001) and IA (60.83 ± 9.95-–36.10 ± 5.16, F = 183.302, df = 1, P < 0.001) were remarkably reduced in the experimental group after GCBT. Conclusion: This study suggests that GCBT can be an effective treatment for those college students struggling with IA, with improving the psychological variables affecting IA
بررسی تاثیر حساسیت زدایی با حرکات چشم و پردازش مجدد بر میزان ترس از هیپوگلیسمی در بیماران دیابتی نوع 2 مراجعه کننده به کلینیک مرکز آموزشی درمانی ولایت در شهر قزوین سال 1397
Get PDFEffect of ambient air pollution and temperature on the risk of stillbirth: a distributed lag nonlinear time series analysis
Get PDFGenotypic and antimicrobial resistance characterizations of Cronobacter sakazakii isolated from powdered milk infant formula: A comparison between domestic and imported products
Get PDFCronobacter sakazakii, an opportunistic foodborne pathogen and a main cause of meningitis in neonates, is usually isolated from powdered milk infant formula (PMIF). At the present study, C. sakazakii were isolated from imported and domestically produced PMIF samples and identified by detection of ompA gene using real-time PCR SYBR green melting curve following the evaluation of antimicrobial susceptibility and genotyping of the isolates employing BOX-PCR and RAPD methods. We detected totally 5% contamination rate and a significantly higher prevalence of C. sakazakii in bulky imported domestically packaged PMIF samples. Also, our isolates were recognized as multidrug-resistant pathogen completely resistant to ampicillin and amoxicillin; and intermediately resistant to ciprofloxacin and tetracycline antimicrobials. Genotype clustering patterns of bulky imported and imported product isolates were identical by both genotyping methods. Far genetic relatedness of domestic isolate to other isolates and the reference strain indicated higher genetic diversity of the domestic isolate genome. Multidrug resistance and diverse population genetic make complicated situation for determination of strategies for infectious disease prevention
Quality of life of family caregivers of patients with a stoma: A cross sectional study from Iran
Get PDFAim:
The family plays a key role in supporting and caring for patients who have a gastrointestinal stoma
because of cancer. This study investigated the quality of life of family members caring for such patients.
Methods:
A descriptive study was conducted in 2020 in Iran. The study sample consisted of 250 family members
caring for cancer patients with an intestinal stoma. The Caregiver Quality of Life Index–Cancer scale
was used to measure quality of life. This scale has 35 questions, which are categorised into four
subscales: mental/emotional burden; lifestyle disruption; positive adaptation; and financial concerns.
The highest possible total score is 140 (35 in each subscale), and a high score indicates a poor quality
of life.
Results:
A total of 250 carers took part in the study. Of these, 143 (57.2%) were men and the average age was
35.1 years. Mean scores of mental/emotional burden, lifestyle disruption, positive adaptation, and
financial concerns were 28.4±41, 17.3±3.2, 19.8±28, and 8.6±1.2 respectively. No significant
relationship was found between participants' quality of life and demographic variables.
Conclusion:
Carers' quality of life is relatively poor. Carers' quality of life need to be improved and support
programmes, devised and delivered by nurses, could have a role in thi
Effects of Chronic Administration of Pioglitazone on Learning and Memory in Rat Model of Streptozotocin-induced Alzheimer’s Disease.
Get PDFBackground Alzheimer’s Disease (AD) is a chronic neurodegenerative disease characterized by abnormal
protein accumulation, synaptic dysfunction, and cognitive impairment. Peroxisome Proliferator-Activated
Receptor-γ (PPARγ) play a crucial role in regulating insulin sensitivity and may serve as potential
therapeutic targets for AD. Pioglitazone (PIOG), as a PPARγ agonist, reduces β-amyloid and tau proteins,
and inhibits neuroinflammation.
Objective This study aims to evaluate the effects of PIOG chronic administration on learning and memory
in rat model of Streptozotocin (STZ)-induced AD
Methods Forty-two male Wistar rats were divided into two groups: A. Normal rats divided into three subgroups
of Control, Dimethyl Sulfoxide (DMSO), and PIOG; and B. AD rats divided into four subgroups of
Vehicle, STZ, STZ+DMSO and STZ+PIOG. The last two AD subgroups received 0.2 mL DMSO and PIOG (10
mg/kg per day) for 21 days. For induction of AD, STZ (3 mg/kg, 10 μl per injection site) were administered
into lateral ventricles. All rates were trained under the Morris water maze task.
Findings PIOG impaired the spatial learning and memory in normal rats. Intracerebroventricular injection
of STZ significantly increased escape latency and swimming time to find the hidden platform compared
to the control group (P<0.05). The amnesic effect of STZ was prevented by PIOG administration such
that the escape latency and swimming time to find the hidden platform in the STZ+PIOG group were
significantly lower than in the STZ+DMSO group (P<0.05). Conversely, the percentage of time spent and
distance swimming in the target quadrant in the probe test in the STZ+ PIOG group rats were significantly
higher than those in the STZ + DMSO group.
Conclusion PIOG administration impaired spatial learning and memory in normal rats, but improved
learning and memory in rats with STZ-induced AD. It can be useful for treatment of cognitive impairment
in AD patients
A Comparative Study on Deoxynivalenol Mycotoxin Level in Wheat Flour and Bread Samples
Get PDFBackground Deoxynivalenol (DON) is one of the most common mycotoxins found in cereal products.
Objective The purpose of this study is to compare the DON contamination level in raw wheat flour and
bread.
Methods In this analytical study with cross-sectional design, a total of 44 wheat flour and bread samples
(Lavash flour and bread, and Barbari flour and bread) were collected. The DON level was measured using
ELISA method. Collected data were analyzed in SPSS software by using ANOVA and t-test considering a
significance level of P≥0.05.
Findings The Mean±SD total DON level in the flour and bread samples was 0.03±0.04 and 0.12±0.21 μg/
kg. The mean DON level in the Lavash and Barbari flour samples was 0.01±0.02 and 0.01±0.01 μg/kg,
and in the Lavash and Barbari bread samples as 0.04±0.03 and 0.16±0.27 μg/kg, respectively. There was
no statistically significant difference in the DON levels between flour and bread samples (P≥0.05).
Conclusion The presence of DON in the studied samples was observed, but its contamination level was
lower than the permissible limit
Prevalence and phylogenetic analysis of gastrointestinal helminths(Nematoda: Trichostrongylidae) in ruminant livestock of northwest Iran
Get PDFTrichostrongylidae family is considered as a group of gastrointestinal nematodes of ruminants with widespread
distribution in the world. The parasites are the major causes of productivity loss in many countries including Iran. This study was
carried out to determine the distribution of abomasal Trichostrongylidae among livestock of Qazvin, Iran. Totally, 160 abomasum
samples including 83 from sheep, 72 from cattle and 5 from goats were collected from slaughterhouses throughout the Qazvin Province.
The ribosomal DNA internal transcribed spacer 2 (ITS2) region was amplified using PCR followed by sequencing 13 different isolates.
Phylogenetic analysis of the identified sequences was performed using MEGA 7 software. The prevalence rate of the nematodes was
19.4% among the specimens. Also, two spices including Marshallagia marshalli and Teladorsagia circumcincta were identified among
the isolates with M. marshalli at higher frequency. No Trichostrongylus spp. was detected in the region. Since livestock plays a major
role in ecosystem balance and as some species of nematodes have a zoonotic nature, it is necessary to proceed with more comprehensive
epidemiologic studies to clarify the infection rate among the human population living in the region
Evaluating the Effects of Vanadyl Sulfate on Biomarkers of Oxidative Stress and Inflammation in Renal Tissue of Rats with Diabetes Type 2
Get PDFVanadyl Sulfate (VS) is an ingredient in some food supplements and experimental drugs. This study
was designed to assay the effects of VS on biomarkers of oxidative stress and inflammation in renal
tissue of rats with diabetes type 2. 30 male Wistar rats were divided into three equal groups as follow:
non-diabetics, non-treated diabetics and VS-treated diabetics. Diabetes type 2 has been induced
through high fat diet and fructose in the animals. Diabetic rats were treated with 25 mg/kgBW of VS
in water for 12 weeks. At the end of study, glucose and insulin were measured using commercially
available kits in serum and biomarkers of oxidative stress and inflammation in renal homogenates of
animals were measured by related methods. Compared to controls, glucose and insulin were increased
significantly in non-treated diabetic rats (p-value <0.05) that showed the induction of diabetes type
2 in rats. The results showed that in VS-treated diabetic rats compared to the non-treated diabetic
group, vanadyl sulfate significantly reduced the glucose and insulin secretion and changed renal
inflammatory and oxidative markers, except protein carbonyl so that we couldn’t find any significant
changes. Our study showed that vanadyl supplementation had positive effects on oxidative stress and
inflammation biomarkers in kidney of diabetic rats