13672 research outputs found
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Hypertension – Adults
No full textThe indicator (key figure) presented here is part of the Diabetes Surveillance indicator set (research project at the Robert Koch Institute 2015 – 2024) with a total of 40 defined indicators or indicator groups. In addition to the indicator results, the methodological approach and the data source are described and the data are provided in aggregated form. All indicators are categorised into four fields of action: (1) Reducing the risk of diabetes, (2) Improving the early detection and treatment of diabetes, (3) Reducing the complications of diabetes, and (4) Reducing the burden and costs of disease. There are indicators for children and adolescents as well as for adults. The results of the Diabetes Surveillance at the end of the project in 2024 are published on the publication server of the Robert Koch Institute (https://edoc.rki.de/handle/176904/12467). In future, some diabetes indicators will be regularly updated with new data as part of the extended surveillance of non-communicable diseases at http://www.gbe.rki.de
Insulin pump therapy for type 1 diabetes – Children and adolescents
No full textThe indicator (key figure) presented here is part of the Diabetes Surveillance indicator set (research project at the Robert Koch Institute 2015 – 2024) with a total of 40 defined indicators or indicator groups. In addition to the indicator results, the methodological approach and the data source are described and the data are provided in aggregated form. All indicators are categorised into four fields of action: (1) Reducing the risk of diabetes, (2) Improving the early detection and treatment of diabetes, (3) Reducing the complications of diabetes, and (4) Reducing the burden and costs of disease. There are indicators for children and adolescents as well as for adults. The results of the Diabetes Surveillance at the end of the project in 2024 are published on the publication server of the Robert Koch Institute (https://edoc.rki.de/handle/176904/12467). In future, some diabetes indicators will be regularly updated with new data as part of the extended surveillance of non-communicable diseases at http://www.gbe.rki.de
Causes of Death in Cancer Patients (CoDiCa)
No full textCancer remains the leading cause of premature death worldwide. While the survival rate of cancer patients continues to improve, non-cancer events including potential long-term and late effects are now competing with cancer as the underlying cause of death. However, limited studies have focused on the cause-specific mortality in overall population of patients with cancer. Mortality patterns and the risk of non-cancer mortality in patients with cancer remain unknown. Therefore, the purpose of this study is to characterize the causes of death among patients with cancer. The results will provide critical insights into shifting mortality trends, helping to improve survivorship care and long-term outcomes for cancer patients.
The objective of this study is to analyze cause-specific mortality among cancer patients in Germany. The study will evaluate mortality patterns based on: (1) cancer type (and stage), (2) calendar year, (3) sex and patient age, (4) time after diagnosis, and (5) histology and mode of treatment (in a later study based on clinical dataset). The corresponding hypotheses are: (1) patients with highly lethal cancers and cancers in advanced stage are more likely to die from cancer-related causes; (2) there are changes in mortality pattern from 1998 to 2021; the proportion of cancer deaths among patients with cancer decreases, while the proportion of non-cancer death gradually increases; (3) older patients with cancer are more likely to die from non-cancer related causes compared to younger patients with cancer; (4) patients with cancer are more likely to die from non-cancer related causes after 10 years compared to the time of their initial cancer diagnosis; (5) patients with cancer who receive chemotherapy are at a higher risk of mortality due to non-cancer diseases such as infectious diseases and ischemic heart disease; (6) patients with advanced cancer are at higher risk of suicide
Health-related quality of life - mental dimension - Adults
No full textThe indicator (key figure) presented here is part of the Diabetes Surveillance indicator set (research project at the Robert Koch Institute 2015 – 2024) with a total of 40 defined indicators or indicator groups. In addition to the indicator results, the methodological approach and the data source are described and the data are provided in aggregated form. All indicators are categorised into four fields of action: (1) Reducing the risk of diabetes, (2) Improving the early detection and treatment of diabetes, (3) Reducing the complications of diabetes, and (4) Reducing the burden and costs of disease. There are indicators for children and adolescents as well as for adults. The results of the Diabetes Surveillance at the end of the project in 2024 are published on the publication server of the Robert Koch Institute (https://edoc.rki.de/handle/176904/12467). In future, some diabetes indicators will be regularly updated with new data as part of the extended surveillance of non-communicable diseases at http://www.gbe.rki.de
Prävalenz Typ-1-Diabetes - Kinder und Jugendliche
No full textDer hier dargestellte Indikator (Kennzahl) ist Teil des Indikatorensets der Diabetes-Surveillance (Forschungsprojekt am Robert Koch-Institut 2015-2024) mit insgesamt 40 definierten Indikatoren beziehungsweise Indikatorgruppen. Zusätzlich zu den Indikator-Ergebnissen werden das methodische Vorgehen und die Datengrundlage beschrieben sowie die Daten in aggregierter Form bereitgestellt. Alle Indikatoren sind in vier Handlungsfelder eingeordnet: (1) Diabetesrisiko reduzieren, (2) Diabetesfrüherkennung und behandlung verbessern, (3) Diabeteskomplikationen reduzieren bzw. (4) Krankheitslast und Krankheitskosten senken. Zudem wird zwischen Kindern und Jugendlichen sowie Erwachsenen unterschieden. Der Ergebnisstand der Diabetes-Surveillance zum Projektende 2024 ist auf dem Publikationsserver des Robert Koch-Institutes (https://edoc.rki.de/handle/176904/12467) veröffentlicht. Zukünftig werden einige Diabetes-Indikatoren als Teil einer erweiterten Surveillance nichtübertragbarer Erkrankungen unter http://www.gbe.rki.de regelmäßig mit neuen Daten aktualisiert werden
Sugar-sweetened beverages - Adults
No full textThe indicator (key figure) presented here is part of the Diabetes Surveillance indicator set (research project at the Robert Koch Institute 2015 – 2024) with a total of 40 defined indicators or indicator groups. In addition to the indicator results, the methodological approach and the data source are described and the data are provided in aggregated form. All indicators are categorised into four fields of action: (1) Reducing the risk of diabetes, (2) Improving the early detection and treatment of diabetes, (3) Reducing the complications of diabetes, and (4) Reducing the burden and costs of disease. There are indicators for children and adolescents as well as for adults. The results of the Diabetes Surveillance at the end of the project in 2024 are published on the publication server of the Robert Koch Institute (https://edoc.rki.de/handle/176904/12467). In future, some diabetes indicators will be regularly updated with new data as part of the extended surveillance of non-communicable diseases at http://www.gbe.rki.de
Treatment Pathways and Clinical Characteristics Among Patients with Metastatic Breast Cancer in Germany: A Retrospective Descriptive Analysis with Data from 2020 to 2023
No full textBreast cancer is the most common cancer among women worldwide and represents a significant health challenge. It is caused by uncontrolled growth of breast tissue cells and can metastasize to other parts of the body if it is not detected and treated in time.
Breast cancer treatment is tailored to the individual and depends on various factors, including type and stage of the tumor, hormone receptor status, and the patient's overall health. For patients with metastatic breast cancer (mBC) the primary treatment modalities include systemic drug therapies such as hormone therapy, chemotherapy, targeted drugs, and immunotherapy. These treatments aim to reduce the tumor size, alleviate symptoms, and prolong survival.
This study will address the gap in our understanding of the real-world treatment patterns and outcomes of mBC in Germany.
The objectives of this study are:
• Conduct a descriptive analysis of incident mBC patients, focusing on their demographic and clinical characteristics.
• Examine the HER2 status distribution and its impact on treatment decisions.
• Classify breast cancer cases according to ICD-10 and ICD-O.
• Describe treatment patterns of all incident mBC patients.
• Analyze overall survival, progression-free survival, and response rate of mBC patients.
This retrospective study will utilize data from the German Centre for Cancer Registry Data (Zentrum für Krebsregisterdaten, ZfKD) at the Robert Koch Institute (RKI), covering diagnosis years 2020 to 2023. Patients with newly diagnosed mBC within this period will be included. Exclusion criteria will involve incomplete records and non-metastatic cases. Statistical analysis will be conducted using appropriate methods and software to examine treatment outcomes and trends over time, such as descriptive statistics and Kaplan-Meier for overall survival. The choice of statistical techniques will be further specified based on the data availability.
The study aims to provide valuable information for patients and various stakeholders involved in mBC management. This will be achieved by improving the understanding of the treatment pathways as well as demographic and clinical characteristics of mBC patients in Germany
Wochenbericht zur hitzebedingten Mortalität KW 34
Get PDFHitzeperioden führen in Deutschland regelmäßig zu einem Anstieg der Mortalität. Um über die
aktuelle Lage in Deutschland zu informieren, wird dieser Bericht während des Sommers 2025
(Juni-September) wöchentlich aktualisiert. Der aktuelle Bericht umfasst Schätzungen der
hitzebedingten Sterbefälle im Zeitraum der Kalenderwochen (KW) 15 bis 34/2025
Wochenbericht zur hitzebedingten Mortalität KW 31
Get PDFHitzeperioden führen in Deutschland regelmäßig zu einem Anstieg der Mortalität. Um über die aktuelle Lage in Deutschland zu informieren, wird dieser Bericht während des Sommers 2025 (Juni-September) wöchentlich aktualisiert. Der aktuelle Bericht umfasst Schätzungen der hitzebedingten Sterbefälle im Zeitraum der Kalenderwochen (KW) 15 bis 31/2025
Beschluss und Wissenschaftliche Begründung der STIKO zur Erweiterung der Indikations- und beruflichen Indikationsempfehlung für die saisonale Influenza-Impfung
No full textDie STIKO hat die aktuelle Situation mit der weltweit starken Ausbreitung von hochpathogenen H5Nx-Viren unter Geflügel, Wasservögeln und anderen Wildvögeln sowie den vermehrten Nachweisen von H5Nx in diversen Säugetierklassen zum Anlass genommen, ihre Influenza-Indikationsimpfempfehlung anzupassen. Zusätzlich sollen nun Personen, die im privaten Umfeld oder arbeitsbedingt häufigen, regelmäßigen und direkten Kontakt zu z. B. Schweinen, Geflügel sowie Wildvögeln oder Robben haben, eine jährliche Impfung im Herbst/Winter mit einem inaktivierten Influenza-Impfstoff erhalten. Im Epidemiologischen Bulletin 29/2025 werden der Beschluss zur Erweiterung der Impfempfehlung sowie die wissenschaftliche Begründung veröffentlicht.Peer Reviewe