Hochschule Bonn-Rhein-Sieg
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HybridKEM - Entwicklung neuer Hybride auf Phosphat/Silicat/Agarose-Basis als Knochenersatzmaterial mit Release-Funktion für Bisphosphonat-Wirkstoffe: Abschlussbericht zum Forschungsvorhaben : Förderlinie "IngenieurNachwuchs - kooperative Promotion" im Rahmen des Programms "Forschung an Fachhochschulen" : Laufzeit des Vorhabens: 01.10.2018 bis 30.09.2022, auf Grund von Hochwasserschäden am Campus verlängert bis 30.5.2023
No full textPrüfungsordnung (studiengangsspezifischer Teil) für den Master-Studiengang Analytische Chemie und Qualitätssicherung am Campus Rheinbach an der Hochschule Bonn-Rhein-Sieg vom 23.03.2023
No full textRichtlinie der Studierendenschaft zur Vergabe von Fördermitteln und Investitionszuschüssen an Fachschaften und studentische Gruppen an der Hochschule-Bonn-Rhein-Sieg vom 04.12.2023
Get PDFRecommending path deviations - a practice-based approach to sustainable consumption
No full textWestern consumption patterns are strongly associated with environmental pollution and climate change, which challenges us with transforming our society and consumption towards a sustainable future. This thesis takes up this challenge and aims to contribute to this debate at the intersection of ICT artifacts and social practices through the examples of food and mobility consumption. The social practice lens is employed as an alternative to the predominant persuasive or motivational lens of design in the respective consumption domains. Against this background, this thesis first presents three research papers that contribute to a broader understanding of dynamic practices and their transformation towards a sustainable stable state. The following research takes up these sections' empirical results that more intensely focus on the appropriation of materials and infrastructures utilizing Recommender Systems. Given this approach, this thesis contributes to three fields - practice-based Computing, Recommender Systems, and Consumer Informatics.Westliche Konsummuster sind stark mit Umweltverschmutzung und Klimawandel verbunden, was uns vor die Herausforderung stellt, unsere Gesellschaft und unseren Konsum in Richtung einer nachhaltigen Zukunft zu transformieren. Die vorliegende Arbeit nimmt diese Herausforderung an und will einen Beitrag zu dieser Debatte an der Schnittstelle von IKT-Artefakten und sozialen Praktiken am Beispiel des Lebensmittel- und Mobilitätskonsums leisten. Die analytische Linse der sozialen Praxis wird als Alternative zum vorherrschenden persuasiven oder motivierenden Designansatz in den jeweiligen Konsumbereichen verwendet. Vor diesem Hintergrund werden in dieser Arbeit zunächst drei Forschungsarbeiten vorgestellt, die zu einem breiteren Verständnis dynamischer Praktiken und ihrer Transformation hin zu einem nachhaltig stabilen Zustand beitragen. Die folgenden Untersuchungen greifen die empirischen Ergebnisse dieses Abschnittes auf und fokussiert auf die Aneignung von Materialien und Infrastrukturen durch Empfehlungssysteme. Mit dieser Herangehensweise leistet diese Arbeit einen Beitrag zu den drei Feldern practice-based Computing, Empfehlungssysteme und Verbraucherinformatik
Analysis of the cervical microbiome in women from the German national cervical cancer screening program
Get PDFPURPOSE
Cervical cancer (CC) is caused by a persistent high-risk human papillomavirus (hrHPV) infection. The cervico-vaginal microbiome may influence the development of (pre)cancer lesions. Aim of the study was (i) to evaluate the new CC screening program in Germany for the detection of high-grade CC precursor lesions, and (ii) to elucidate the role of the cervico-vaginal microbiome and its potential impact on cervical dysplasia.
METHODS
The microbiome of 310 patients referred to colposcopy was determined by amplicon sequencing and correlated with clinicopathological parameters.
RESULTS
Most patients were referred for colposcopy due to a positive hrHPV result in two consecutive years combined with a normal PAP smear. In 2.1% of these cases, a CIN III lesion was detected. There was a significant positive association between the PAP stage and Lactobacillus vaginalis colonization and between the severity of CC precursor lesions and Ureaplasma parvum.
CONCLUSION
In our cohort, the new cervical cancer screening program resulted in a low rate of additional CIN III detected. It is questionable whether these cases were only identified earlier with additional HPV testing before the appearance of cytological abnormalities, or the new screening program will truly increase the detection rate of CIN III in the long run. Colonization with U. parvum was associated with histological dysplastic lesions. Whether targeted therapy of this pathogen or optimization of the microbiome prevents dysplasia remains speculative
Effect of Chain Extending Cross-Linkers on the Disintegration Behavior of Composted PBAT/PLA Blown Films
No full textA biodegradable blend of PBAT—poly(butylene adipate-co-terephthalate)—and PLA—poly(lactic acid)—for blown film extrusion was modified with four multi-functional chain extending cross-linkers (CECL). The anisotropic morphology introduced during film blowing affects the degradation processes. Given that two CECL increased the melt flow rate (MFR) of tris(2,4-di-tert-butylphenyl)phosphite (V1) and 1,3-phenylenebisoxazoline (V2) and the other two reduced it (aromatic polycarbodiimide (V3) and poly(4,4-dicyclohexylmethanecarbodiimide) (V4)), their compost (bio-)disintegration behavior was investigated. It was significantly altered with respect to the unmodified reference blend (REF). The disintegration behavior at 30 and 60 °C was investigated by determining changes in mass, Young’s moduli, tensile strengths, elongations at break and thermal properties. In order to quantify the disintegration behavior, the hole areas of blown films were evaluated after compost storage at 60 °C to calculate the kinetics of the time dependent degrees of disintegration. The kinetic model of disintegration provides two parameters: initiation time and disintegration time. They quantify the effects of the CECL on the disintegration behavior of the PBAT/PLA compound. Differential scanning calorimetry (DSC) revealed a pronounced annealing effect during storage in compost at 30 °C, as well as the occurrence of an additional step-like increase in the heat flow at 75 °C after storage at 60 °C. The disintegration consists of processes which affect amorphous and crystalline phase of PBAT in different manner that cannot be understood by a hydrolytic chain degradation only. Furthermore, gel permeation chromatography (GPC) revealed molecular degradation only at 60 °C for the REF and V1 after 7 days of compost storage. The observed losses of mass and cross-sectional area seem to be attributed more to mechanical decay than to molecular degradation for the given compost storage times
A systematic literature review about the consumers’ side of fake review detection – Which cues do consumers use to determine the veracity of online user reviews?
No full textBackground
Consumers rely heavily on online user reviews when shopping online and cybercriminals produce fake reviews to manipulate consumer opinion. Much prior research focuses on the automated detection of these fake reviews, which are far from perfect. Therefore, consumers must be able to detect fake reviews on their own. In this study we survey the research examining how consumers detect fake reviews online.
Methods
We conducted a systematic literature review over the research on fake review detection from the consumer-perspective. We included academic literature giving new empirical data. We provide a narrative synthesis comparing the theories, methods and outcomes used across studies to identify how consumers detect fake reviews online.
Results
We found only 15 articles that met our inclusion criteria. We classify the most often used cues identified into five categories which were (1) review characteristics (2) textual characteristics (3) reviewer characteristics (4) seller characteristics and (5) characteristics of the platform where the review is displayed.
Discussion
We find that theory is applied inconsistently across studies and that cues to deception are often identified in isolation without any unifying theoretical framework. Consequently, we discuss how such a theoretical framework could be developed
