Jurnal Kedokteran Universitas Lampung
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Faktor-Faktor yang Mempengaruhi Ketertarikan Mahasiswa Kuliah Dalam Kelas Besar
Full text linkKuliah masih merupakan salah satu strategi pembelajaran yang tidak bisa dihilangkan. Dengan adanya kuliah mahasiswa bisa mendapatkan pengetahuan dari ahlinya walaupun kurikulum yang digunakan adalah kurikulum Problem-Based Learning (PBL). Akhir-akhir ini banyak keluhan karena motivasi mahasiswa kuliah menurun. Ada banyak faktor yang mempengaruhi mahasiswa untuk kuliah atau mengikuti perkuliahan. Faktor tersebut di antaranya adalah metode PBL yang mendukung mahasiswa untuk mengembangkan keterampilan Self-Directed Learning (SDL) sehingga mahasiswa terbiasa mandiri. Kemudian keterampilan dosen dalam mengajar, mengaktifkan, dan memotivasi mahasiswa. Faktor lainnya adalah motivasi mahasiswa yang rendah, gaya belajar yang tidak sesuai, dan lingkungan belajar yang tidak mendukung. Simpulan, Untuk meningkatkan ketertarikan mahasiswa bisa dilakukan dengan mengembangkan strategi mengajar di dalam kelas. [JuKe Unila 2015; 5(9):115-118
Bakteriological Quality Of Refill Drinking Water At Refill Drinking Water Depots In Bandar Lampung
Full text linkDEPRESSION SYMPTOM AND NUTRITIONAL STATUS OF ELDERLY IN JEMBER REGENCY
Full text linkBackground: Indonesia is one of countries which have inhabitant of elderly highest ever. In 2020 Indonesia will be the fifth highest of elderly. East Java province has included in groups the area having structure aging population. East Java have the number of elderly second highest after Yogjakarta (10.4%). The growing number of elderly would have become complex problem for senior family and community including the physical aspects, biological, mental, or socially economy. Along with the matter will affect on nutrition status for elderly. The aim of this studi is to determine correlation between depression symptom with nutritional status of elderly in Jember regency. Method: This research was observational with cross sectional design. Subjects were elderly in Sumbersari sub-district, Jember regency who fulfilled inclusion criteria. Research subjects consisted of 120 elderly. Depression symptom was measured with Geriatric Depression Scale-15 (GDS-15), dietary intake with semi quantitative food frequency questionnaire (SQFFQ) method, and nutritional status was determined based on body mass armspan (BMA). Data were analyzed with chi squaretest and multiple logistic regression. Result: The proportion of depression symptom in Sumbersari sub-district, Jember egency was by 27,5%. Most of the subjects who suffer depression symptom have more and less nutritional status 69,7% (23 elderly), and have a good nutritional status for as many as 10 elderly (30.3%). The greatest distribution of subjects with depression as much as 31 elderly (33.7%) and the subject with no depression as many as 61 elderly (66.3%) female subjects in the group scattered. Conclusion: Significant correlation was found between depression symptomand nutritional status (p=0.027). [JuKe Unila 2014; 4(8):185-193
HEART VALVE DISEASE IN HYPERTHYROIDISM
Full text linkThe incidence of heart valve disease, especially mitral valve prolapse was first reported in hyperthyroid heart disease in 1981. Incidence of heart valve disease in the form of mitral regurgitation (MR) or tricuspid regurgitation (TR) reached 23% in patients with hyperthyroidism. 45 years old male with a chief complaint tightness, worsened since 1 week before entering the hospital. Since 2 years ago patient often feels palpitations and breathless if activity. About 5 months ago, patient was sweating a lot and tremble, increase in appetite but weight going down. Defecation 5-6 times a day. Visible and palpable lump in the neck diameter ±5 cm, soft, ned, part moves while swallowing. Laboratory showed free T4: 7.550, sensitive TSH: 0.010. Thoracic X-ray showed cardiomegaly with cardiac waist disappeared. ECG showed atrial fibrillation. Echocardiography showed LA + LV dilatation TAPSE 1.91, AR Moderate, Severe MR, AML prolapse in A2 and PML with EF: 62.7%. Ultrasonography showed Throid hyperthyroidism and thyroid scan results with the impression difusa bilateral goitre within crease of total thyroid uptake. Patients received digoxin, furosemide, PTU. Patients then performed MV Repair and AV Repair. The mechanism of valvular heart disease relationship in hyperthyroidism has not been completely understood. In patients with MPV, some studies have shown a high prevalence of HLA-Bw35. Increased production and secretion of acid polymukosakarida in Graves can accumulate all the heart valves, especially the mitral valve, causing the valve to thicken (myxomatous). MR in hyperthyroidism is said to be a consequence of mitral annulus dilatation due to the left ventricle is dilated. It has been reported also a gernline mutations of thyrotropin receptor gene in Chinese families with thyrotoxicosis and MVP. In hyperthyroid patients is important to explore the patient's cardiovascular condition, including the possibility of valve disorders. [JuKe Unila 2014; 4(8):225-232
SOCIAL DETERMINANTS CHARACTERISTICS OF TUBERCULOSIS PATIENTS IN BANDAR LAMPUNG MUNICIPALITY
Full text linkBackground: World Health Organization through tuberculosis (TB) control averted up to six million deaths and cured thirty-six million people in 1995-2008, but had less success in reducing TB incidence, especially in thirteen high burden countries, including Indonesia. Therefore, TB control will need to have more emphasis on the issues of social determinants, as social determinants affect TB’s incidence directly and/-or through TB’s risk factors. This study aimed to identify social determinants characteristics of TB patients in Bandar Lampung, during period January–July 2012. Methods: The research setting was at twenty-seven primary health centers and one hospital that have implemented the Directly Observed Treatment Shortcourse (DOTS) strategy in Bandar Lampung. Respondents of this research were 238 TB patients and 238 patients without TB. Research variables consisted of social determinants, which measured through its indicators (education, occupation, family income, and social class). Data have been collected by using questionnaire and then was analyzed with Stata 11. Results: Tuberculosis patients had lower education, occupation, family income, and social class compare to patients without TB. Conclusion: The knowledge of social determinants characteristics of TB patients can be used to support TB control program, particularly to implement DOTS strategy together with improving social determinants. [JuKe Unila 2014; 4(8):166-172
INHERITED VARIATIONS IN DRUGS EFFECT INDEPENDENT IN PHARMACOKINETIC: POLYMORPHISM IN PHASE II BIOTRANSFORMATION ENZYMES
Full text linkPhase II enzymes play an important role in the biotransformation of endogenous compounds and xenobiotics to more easily excretable forms as well as in the metabolic inactivation of pharmacologically active substances. The purpose of phase II biotransformation is to perform conjugating reactions. These include glucuronidation, sulfation, methylation, acetylation, glutathione, and amino acid conjugation. In general, the respective conjugates are more hydrophilic than the parent compounds. Polymorphism in Phase II drug metabolism enzymes may have role in diseases, cancer, and others. This review discuss brief about polymorphism in Phase II drug metabolism enzyme. [JuKe Unila 2014; 4(8):254-268