Jurnal Kedokteran Universitas Lampung
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The influence of Piper retrofractum Vahl (Java's chili) extract towards lipid profile and histology of rats coronary artery with high-fat diet
The Development of Medical Biochemistry Text Book to Improve the Quality of Learning of Basic Science 1 (BS1) Block at Medical Faculty the University of Lampung
Relationship Between Pfmdrl Gene Polymorphisms with Response Therapy Against Artesunat Amodiakuinin Uncomplicated Falciparum MalariaPatientsin Puskesmas Hanura, Pesawaran Regency, Lampung
THE RELATIONSHIP BETWEEN NUTRITIONAL STATUS AND IMMUNONUTRITION INTAKE WITH IMMUNITY STATUS
Background: Immunity status is a system that protect the human body against foreign substances. Good immunity status can prevent various diseases. Several risk factors that make a person susceptible to infection is less nutritional status. Immunonutrition intake consists of some specific nutrient components that can form the immune system. This study aims to determine the relationship between nutritional status and intake of immunonutrition (proteins, zinc and iron) with the immunity status. Method: This study is an analytic observational study with cross sectional design at 78 students of medical faculty in Lampung university. Sampling was taken by proportionated random sampling. Nutritional status was obtained from anthropometric examination using the body mass index criteria, the immunonutrition intake taken through 3x24 h food recall and the immunity status was taken by lymphocyte numbers. Result: The results showed that in general, the immunity status are good (58.97%), nutritional status are normal (66.67%), protein intake are adequate (62.82%), zinc and iron intake classified inadequate (71,79%; 65,38%). There is a significant association between the intake of protein and iron with the immunity status (p=0.004; p=0.014) and there is not significant association between nutritional status and intake of zinc with the immunity status (p=0.192; p=0.599). From the four independent variables that have a more meaningful relationship is the intake of protein and iron. Conclusion: The intake of immunonutrition (protein and iron) was associated with the immunity status. [JuKe Unila 2014; 4(8):158-165
THE BEHAVIOR IN USING OF PESTICIDES ON RICE FARMERS AT RJ VILLAGE BANDAR LAMPUNG
Background: Based on the Health Law No. 36 year 2009 part 164(1) and (2) about the Occupational Health mandates that every workplace should hold an Occupational Health and Safety (OHS) to prevent health problems for workers. This is also include for workers in the agricultural sector that uses pesticides. The behavior of using pesticide must be on the rules set by the Ministry of Health of the Republic of Indonesia. Study about the behavior of using pesticides on farmers at the RJ village of Bandar Lampung. Method: Design of this study was a cross sectional study. Sample of this study 50 farmers. Data were collected by using interviews and questionnaire. The behavior of using pesticides include: the use of Personal Protective Equipment (PPE), the direction of spraying, washing hands after spraying, changing clothes after spraying, taking a bath after spraying, and smoking after spraying. Result: The use of PPE was complete about 8%, spraying pesticide in the direction of the wind about 80%, washing hands after spraying about 66%, changing clothes after spraying about 82%, taking a bath after spraying about 66% and smoking after spraying about 50%. Conclusion: Behavior on using PPE and smoking after spraying was low. All sectors need to support farmers’ behavior to use pesticides wisely. The impact is to increase farmers’ health status. [JuKe Unila 2014; 4(8):180-184
THE EFFECT OF ETHANOLIC EXTRACT OF CENTELLA ASIATICA (L) URBAN ADMINISTRATION TOWARDS THE THICKNESS OF PYRAMIDAL LAYER IN THE CA1 REGION OF HIPPOCAMPUS OF SPRAGUE DAWLEY RATS AFTER CHRONIC RESTRAIN STRESS
Background: Stress has been shown can change the structure of the brain, especially in the cornu ammonic (CA) I region of hippocampus. Centella asiatica or pegagan as herbal neuroprotector was investigated. The study aimed to determine the effect of ethanolic extract of C. asiatica to the thickness of pyramidal layer in the CA1 region in rats subjected to chronic restrain stress (CRS). Method: This experimental study used post test only group design. Thirty five rats were divided into 6 groups: non stress group (control) and stress only group pulvis gum arabicum (PGA), positive control group (treated with fluoxetin 10mg/kgBW), and 3 treatment groups are treated with C. asiatica 150, 300, and 600mg/kgBW respectively. All groups except non stress group were subjected to CRS, for 6 hours per day for 21 days. Fluoxetin, PGA, and C. Asiatica were applied 30 minutes before CRS done. Rats were sacrificed at the end of 24th day and were perfused transcardially. Processed brain tissue stained with toluidine blue, and measured with Image Raster program. Result: The thickness of pyramidal layer in the CA1 region are increasing significantly in treatment groups which treated with 150 and 300 kg/BW of C. asiatica, but not significant which treated with 600mg/kgBW ethanolic extract of C. asiatica. Conclusion: Ethanolic extract of C. asiatica can improve thickness of pyramidal layer in the CA1 region of hippocampus of Sprague Dawley rats after chronic restrain stress. [JuKe Unila 2014; 4(8):202-207
APPLICATION OF PAVLIK HARNESS IN DEVELOPMENTAL DYSPLASIA OF THE HIP (DDH)
Developmental dysplasia of the hip (DDH) is a spectrum of pathology ranging from acetabular dysplasia with minor instability until acetabular dysplasia with hip dislocation. The incidence of DDH that require treatment is 5.1 per 1000 live birth. Early detection is important to deliver good outcome and lessen complication. Careful history taking, physical examination and ultrasonography, have increased the sensitivity in establishing diagnose of DDH. Pavlik harness is the mainstay of treatment for infant who has not commenced crawling. Despite the fact of high success rate, the use of Pavlik harness is still uncommon in Indonesia. This paper reports a case of DDH treated with Pavlik harness and assessed regularly with ultrasonography. A 3 months girl with developmental dysplasia of the left hip. The initial ultrasound shows α angle 49.40 and β angle was 50.20, femoral head subluxated to superolateral aspect. The patient had Pavlik harness and followed up with serial ultrasound at 1st, 3rd and 4th month’s time. Having had 4 months of Pavlik harness, the α angle of the left hip became 630, and β angle 490 with good structure of ilium. Femoral head was smooth and no signs of avascular necrosis. The hip has full range of motion. Parents have no difficulty in taking care of their daughter daily activities such as taking a bath, changing napkin, and clothes. This implicates, patient treated using Pavlik harness showed good outcome clinically and ultrasonographically. Pavlik harness has been proven to be a safe, simple and user friendly method for treatment of DDH before crawling age. The good result obtained from this case could initiate application of pavlik harness in larger population of early detected DDH in Indonesia. [JuKe Unila 2014; 4(8):208-217