Journal of Agromedicine and Medical Sciences
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Diet Reduce Apnea Hypopnea Index (Ahi) Score in Obstructive Sleep Apnea Patient: Systematic Review and Meta-analysis
Obstructive sleep apnea (OSA) is a breathing disorder during sleep that can cause obstruction to the flow of breathing with characteristics such as collapse of the upper airway which can cause breathing to stop, either completely (apnea) or partial (hypopnea). Based on a study of taxi drivers in Jakarta, it was found that 52,5% of the sample had OSA. One of the main factors for OSA is obesity. Based on The American Academy of Sleep Medicine (AASM) recommends weight loss through lifestyle modifications (eg applying diet) as a treatment option for AHI improvement in OSA. The purpose of writing this article is to prove that adopting a diet can reduce the apnea hypopnea index (AHI) of OSA. The method in this study is a systematic review and meta-analysis using secondary data derived from PubMed, Science Direct, and Springer databases published from 2019 to 2022.. A total of six randomized controlled trial (RCT) articles were investigated by meta-analysis The weighted mean difference in AHI (-6,77 event/d with 95% CI: -13,42 to -0,1) significantly favoured diet over control arms. Based on the results of a systematic review and meta-analysis of six articles, the application of a diet is proven to reduce AHI scores in OSA patients.
Keywords: Obstructive sleep apnea, Apnea hypopnea index, Die
Impact of the User-Friendliness of BalitaGrow+ on Compliance with Children's Daily Nutrition Column Completing
Abstract
Nutritional imbalances can lead to malnutrition which can affect children's physical and cognitive growth and development. Advances in science and technology have created opportunities for innovation in the form of health applications to help monitor children's growth and development, nutritional status, and children's daily nutritional intake. The factor that influences the intention to use technology is the ease of use. This indicates that the easier the application is to use, the higher a person's interest and compliance will be in using the application regularly. This research aims to determine the effect of ease of use of the BalitaGrow+ application on compliance with filling in the daily nutrition column for children in Rambigundam Village, Jember. This research was an analytical observational research with a cross sectional approach with a sample size of 35 people who meet the criteria. Data analysis used univariate tests and bivariate used the Spearman Rank correlation test. The results obtained from 35 respondents showed that 34 people (97.1%) found it easy to use the BalitaGrow+ application and 31 people (88.6%) had good compliance in filling in the child's daily nutrition column in the application. The results of statistical analysis showed a significance value of p value >0.05 (0.726). So it can be concluded that there was an insignificant influence between the ease of use of the BalitaGrow+ application on compliance with filling in the daily nutrition column for children in Rambigundam Village, Jember. It is suggested to increase the sample size and investigate other influenced factors for future study.
Keywords: health application, ease of use, compliance of filling, children’s nutritio
Correlation Analysis of Body Weight with Insulin Resistance and Leptin Levels in Farm Workers
Insulin resistance is a pathological condition resulting from impaired insulin response which causes increased insulin production as a form of compensation from pancreatic beta cells. A stable body weight can prevent insulin resistance and excessive body weight can be a predisposing factor insulin resistance. Individuals with insulin resistance will experience an increase leptin levels 2.3 times more than normal individuals. The aim of this study was to analyze the correlation between body weight and insulin resistance and leptin levels in farm workers. This research method is a cross-sectional analytical observational study conducted from April to September 2023. This research has taken primary data in the form of body weight, fasting blood glucose levels, and insulin and leptin levels from 46 farm worker respondents in Wringin Agung Village, Jombang District, Jember Regency. The results of the Pearson Correlation analysis showed that there was no correlation between body weight and insulin resistance and leptin levels in farm workers. The results of the analysis between body weight and insulin resistance were p = 0.265 with a correlation coefficient of 0.168, which means the degree of correlation is very low. The results of the analysis between body weight and leptin levels were p = 0.870 with a correlation coefficient of 0.025, which means the degree of correlation is very low. The conclusion of this study is that there is no significant correlation between body weight and insulin resistance and leptin levels in farm workers.
Keywords: Body weight, insulin resistance, leptin level
Association between Physical Activity with Burnout Syndrome After the Second Wave of the COVID-19 Pandemic in Health Workers at RSD dr. Soebandi Jember
Health workers have a key role in handling the COVID-19 pandemic. Working in a stressful environment can affect the emotional stability of health workers and can trigger burnout syndrome. Physical activity is one of the factors that can trigger burnout syndrome. Therefore, this study was conducted to analyze the relationship between physical activity and the incidence of burnout syndrome after the peak of the second wave of the COVID-19 pandemic among health workers at RSD dr. Soebandi Jember. This cross-sectional analytic observational study conducted from November to December 2021 was attended by 84 doctors and nurses working at RSD dr. Soebandi. The data were obtained using the Global Physical Activity Questionnaire and the Maslach Burnout Inventory. Ordinal logistic regression analysis showed a significant relationship between work activities and the level of burnout syndrome (p = 0.04). The effect of physical activity on burnout syndrome in this study was 32%. Our recommend is that further research is needed on the factors that can affect burnout syndrome with more objective research methods so that more valid results are obtained.
 
Combination of Body Acupuncture with Scalp and Ear Microacupuncture in Treating Alzheimer's Dementia in Elderly, A Case Report
Dementia refers to impairment in more than one domain of cognitive function. The most common cause of dementia is Alzheimer's dementia (AD). AD is associated with the influence of amyloid, oxidative stress, as well as abnormal phosphorylation of the protein Tau which forms neurofibrillary plaques in neurons. Clinical symptoms include progressive memory impairment for current events, cognitive impairment, general confusion, agitation, delusions, social disinhibition, and paranoia. A 68 year old man complained of rapid forgetfulness and decreased cognitive function accompanied by insomnia. Acupuncture manual therapy was performed at points GB20, LI4, HT7, KI3 bilaterally and EX-HN1, EX-HN3, GV20, CV9, CV4, CV3. Combine with scalp acupuncture Zhu Scalp Head and Face, as well as bilateral anterior hypothalamus and master cerebral ear points. Electroacupuncture 2 Hz continuous wave electroacupuncture at points ST25-ST28, CV12-CV6, and ST36-SP6. Therapy is carried out 2 times a week. Evaluation using MMSE ad PSQI. After 10 treatments, there was improvement in clinical symptoms, MMSE and PSQI scores. Manual acupuncture and electroacupuncture, a combination of body points, scalp and ear microcupuncture are useful in the management of Alzheimer's dementia accompanied by insomnia as non-pharmacological adjuvant therapy with positive results.
Keywords: Manual acupuncture, electroacupuncture, scalp microacupuncture, ear microacupuncture, Alzheimer's dementi
Fibroma of the Vastus Lateralis Tendon Sheath in the Thigh of the 58-year-old Female: A Rare Case Report
Background: Fibroma of the tendon sheath (FTS) is a rare slow-growing noncancerous fibrous tumor that is usually small, painless and involves the upper extremity tendons in young adult males. FTS of the lower extremity is an unusual and underreported variety that poses a diagnostic preoperative challenge. Case description: We report an atypical case of a large fibroma of the vastus lateralis tendon in a 58-year-old female presented with a painful lump in her right thigh within the past six months. Physical examination showed a hard firm mass approximately 6 cm in diameter palpated in the anterior of the lower thigh. The mass was smooth, mobile, solid, and had well-defined borders. There was no adhesion to the skin, redness, or tenderness. MRI showed a 4,2 x 5,8 x 6,2 cm tumor with isointense signals on T1-weighted images (T1WI), heterogeneous hypointense signals on T2-weighted images (T2WI), and hyperintense signals on FatSat images. Biopsy revealed no malignant findings and the tumor had been surgically resected. Imaging studies for FTS have rarely been described, T1WI often show a low signal mass, with slight isointense to hypointense to the muscle. The T2WI’s appearance of FTS is more variable. Conclusion: In spite of rarity, FTS must still be included as a differential diagnosis of a thigh mass especially if the mass is painful and benign-appearing on physical exam and radiology
Comparison of Cyclosporine and Steroids in Treating Severe Allergic Conjunctivitis in Children: an Evidence-based Case Report
The efficacy of cyclosporine compared with corticosteroid in reducing symptoms and signs in children with severe allergic conjunctivitis, either in vernal keratoconjunctivitis or atopic keratoconjunctivitis, is still unknown. Here we present the case of an 8-year-old boy with a case of allergic keratoconjunctivitis. The patient had been given steroid eye drops (Dexamethasone 1 mg) for 2 weeks and only slight improvement was found. Considering the steroid’s long-term effects, the doctor prescribed cyclosporine eye drops. Therefore, this case study is conducted to compare the better efficacy between cyclosporine eye drops and steroid eye drops as a treatment for severe allergic conjunctivitis. After conducting a systematic literature analysis following the PRISMA guidelines, full-text analysis was carried out on two RCTs by assessing their validity, clinical importance, and applicability according to the Oxford CEBM criteria. One of the studies did not meet the validity criteria, while another study showed that cyclosporine eye drops that were given to patients with severe vernal keratoconjunctivitis could reduce signs and symptoms. There was no significant difference between cyclosporine eye drops and dexamethasone eye drops. Cyclosporine's function to reduce signs and symptoms of severe allergic conjunctivitis in children is equivalent to that of corticosteroids.
Keywords: Cyclosporine, corticosteroid, severe allergic conjunctivitis, therap
Approach to Refractory Hypoglycaemia in a Patient with Hepatocellular Carcinoma: A Case Study and Literature Review
Symptomatic hypoglycaemia in patients without underlying diabetes is uncommon. Etiology of non-diabetic hypoglycaemia varies from hyperinsulinism, hormone deficiencies, malignancies, to critical illness. This case report illustrates the attempt to determine the cause of refractory hypoglycaemia in a 46 years old male patient with underlying hepatocellular carcinoma (HCC). Anamnesis and examinations have narrowed differential diagnosis to concurrent systemic illness (liver failure due to HCC) or paraneoplastic syndrome from non-beta cell tumors, referred as non-islet cell tumor hypoglycaemia (NICTH). It was noted that the absence of chronic liver disease stigmata has put NICTH as the possible main cause. Deciding what diagnostic modalities needed to perform to establish the diagnosis eventually relies on clinical judgement while taking cost-effectiveness and patients’ preference in consideration, particularly in low-resource settings. Nonetheless, the main goal of treating hypoglycaemia is to immediately achieve and sustain euglycemia which can be achieved conservatively or definitively with surgery despite the etiology.
Keywords: Hepatocellular carcinoma, Hypoglycaemia, NICTH
Analysis of Determinants of Tuberculosis in Stunted Toddlers in Rambipuji, Jember
Tuberculosis (TB) and stunting remain serious health problems in Indonesia. Stunting can impact a child's ability to resist infections, including TB. Stunted toddlers are more vulnerable to contracting TB compared to those with normal nutritional status. This research aims to explore the relationship and influence of TB risk factors on the occurrence of TB in stunted toddlers. This research is an analytical descriptive research with a cross sectional design. The research sample consisted of 183 stunted toddlers from eight villages in the Rambipuji sub-district, Jember. The research procedures included interviews, direct observations, and TB examinations in children. Interviews were conducted with the parents/guardians of the child respondents. Observations and direct measurements were performed to determine the physical characteristics of the respondents' living environments, including household density, ventilation area, natural lighting, humidity, and room temperature. The diagnosis of TB in children was established based on a scoring table for childhood TB. From the research findings, 15 children tested positive for TB (8.2%). Bivariate analysis showed a value of p <0.05 for nutritional status, close contact, household density, ventilation, and natural lighting factors. Multivariate analysis revealed significant results for close contact (p=0.000; OR=39.563), household density (p=0.015; OR=9.659), and nutritional status (p=0.029; OR=6.718) as risk factors. In conclusion, it can be inferred that the risk factors associated with TB occurrence in stunted toddlers include nutritional status, close contact history, household density, ventilation, and natural lighting. The factors influencing TB occurrence in stunted toddlers are close contact history, household density, and nutritional status.
Keywords: risk factor, stunted toddler, tuberculosi
Ventricular Septal Defect And Maternal History Of Epilepsy: A Case Report
Pregnancy with epilepsy can cause major risks for both the mother and the offspring. It is known that the use of antiepileptic drugs (AEDs) during pregnancy can increase the risk of cardiac malformations. This journal reports a 19-day-old male infant who came with complaints of shortness of breath and a blue lip 2 days before admission. The mother had a history of epilepsy and had regularly taken epilepsy medication since before pregnancy. Physical examination revealed cyanotic lips, chest wall retraction, coarse crackles, and murmurs. The patient's symptoms and signs were associated with congenital heart disease, so he was further observed in the NICU. After bedside echocardiography, the results showed a patent foramen ovale and perimembranous ventricular septal defect. The teratogenic effect of AED is thought to be one of the major causative factors of congenital heart disease. A ventricular septal defect is the most common cardiac malformation found in population-based studies. The long-term effects of AED exposure during pregnancy require further investigation, both in terms of the type of AED (old or new) and the duration of AED consumption. It is important to educate mothers-to-be about this, especially to avoid the risk of congenital heart disease in their offspring.
Keywords: epilepsy, ventricular septal defect, cardiac malformation