Journal of Agromedicine and Medical Sciences
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Risk Factors Analysis of Hypertension Incidence at Karangtengah Public Health Center, Wonogiri Regency
Get PDFHypertension is the most common disease found in Karangtengah Health Center, Wonogiri Regency. The incidence of hypertension can be influenced by factors such as: factor that can not be changed consists of age, gender, family history of illness and modifiable factors consisted of obesity, occupation, and smoking history. Of these risk factors, still unknown factors which increse the incidence of hypertension in Karang Tengah Public Health Center. The purpose of this study was to determine the relationship of these risk factors with the incidence of hypertension and the determinants of the incidence of hypertension in Karangtengah Public Health Center, Wonogiri Regency. This type of research is analytic observational with a cross-sectional design. The sample of this study used the total sampling method, namely all medical record data of new adult patients (>26 years) with a history of chronic diseases who came to Karangtengah Public Health Center, Wonogiri Regency in October 2020 and this study was conducted in March 2021. There were 76 patients. Most of the patients had hypertension (n=42; 55.3%), including the category of elderly (n=55; 72.4%), women (n=41; 53.9%). More patients had a family history of disease (n=50; 65.8%), were obese (n=40; 52.6%), had minimal work activities (n=44; 57.9%), and had a history of smoking (n=42; 55.3%). The risk factors associated with the incidence of hypertension were age, gender, family history of disease, BMI, occupation, and smoking history (all p<0.05).
Keywords: Hypertension, age, family history, BMI, occupatio
Wrist Ankle Acupuncture (WAA) and Body Acupuncture Accelerates Neurorehabilitation in Bell's Palsy: A Case Report
Get PDFBell’s Palsy (BP) is an acute unilateral facial paralysis due to idiopathic inflammation of the peripheral facial nerve. Corticosteroids, antiviral drugs, and physical therapy could be useful to treat BP, however these treatments could not bring complete recovery. Acupuncture could be an alternative option for BP and to show its effectiveness, we present a case report, a patient with BP treated with acupuncture. A 48-year-old female patient, a kindergarden teacher, already treated with corticosteroid and antiviral agents as soon as BP was diagnosed. Six weeks later, patient didn’t recover, with House-Brackmann score stage 3. Acupuncture was perfomed at local and distance acupoints at ears, body and face. Wrist Ankle Acupuncture (WAA) L1,2; ear acupuncture at zero point; and body points were stimulated by electroacu-puncture. After acupuncture therapy, the House-Brackmann score was grade 2. Medical options for the sequelae of BP are limited. Acupuncture’s effectivity in Bell palsy patients’ should be shown with more clinical studies.
Keywords: Acupuncture; Wrist Ankle Acupuncture; Bell’s Palsy; Recover
The Effectiveness of Tamarindus indica Extract in Total Osteoblast Cell of Male Wistar Rat’s Femur Bone Induced by Aluminium
Get PDFAluminum is widely used in life but includes non-essential metals toxic to the human body that most accumulates in the femur. Aluminum is toxic because it increases the number of free radicals resulting in oxidative stress that causes osteoblast apoptosis. Tamarindus indica has the most potent antioxidant effect on the seed. The polyphenol content in Tamarindus indica seed are myricetin, procyanidin B2, and caffeic acid. Antioxidants in Tamarindus indica seed have mechanism of donating electrons from the -OH group in the phenolic ring to stop oxidative chain reactions and prevent the formation of hydroxyl radicals and lipid peroxidation that play a role in cell apoptosis. The purpose of this study to determine the effect of giving Tamarindus indica extract on the total osteoblasts of femur bone in male wistar rats induced by aluminum. This research is a true experimental in vivo with randomized post-test only control group design using 25 male Wistar rats divided into five groups. Aluminum is given orally dose 300mg/kgBB and Tamarindus indica extract dose 25, 50, 100mg/kgBB for 10 weeks. The results of this study indicate the average total of osteoblasts in groups K, P1, P2, P3, P4 are 15.21 ± 1.71; 18.48 ± 3.65; 17.8 ± 7.05; 17.13 ± 1.16; 16.74 ± 5.71. Data analysis used the Kruskal Wallis test. The results of data analysis showed that there was no significant differences in all groups (p = 0.581). Based on the results of this study, Tamarindus indica extract that was given to male wistar rats induced by aluminum for 10 weeks had no effect on the total osteoblasts
Comparison of Sodium Levels in Patients with Stage V Chronic Kidney Disease Whose Using New and Re-use Hemodialyzer in Hemodialysis Installation RSD dr. Soebandi Jember
Get PDFStage V Chronic Kidney Disease (CKD) is one of the most common medical case in the world. Stage V CKD defined as a condition where the renal function decrease progressively, marked by the GFR <15/ml/minute/1,73 m2, with or without kidney damage history for three months. Patients diagnosed with Stage V CKD often needs kidney replacement therapy, one of which is hemodialysis. The cost needed for hemodialysis was considered as too expensive, forcing lots of medical staff in most countries using the method known as re-use hemodialyzer. Re-use hemodialyzer is a term for using the same hemodialyzer (or hemodialysis machine) for the same patient but on a different therapy session. The main purpose for this research is to investigate the sodium level in patients with Stage V CKD whose using new and re-use hemodialyzer in Hemodialysis Installation of RSD dr. Soebandi Jember. Analytic Observational Study is used for this research combined with Cross Sectional Study in December 2018. Total of 19 samples chosen with inclusion and exclusion criteria. Collected data is analyzed using paired t-test. The conclusion that can be obtained from this research is that there is no significant difference between sodium level in patients with Stage V CKD whose using new and re-use hemodialyzer (p=0,904). The effectivity and quality of the hemodialyzer is thought to be the main factor for this result.
Keywords: Chronic Kidney Disease, sodium, re-use hemodialyze
The Potension of Aditory Nerve Damage on Milling Industry Workers in Jember Regency
Get PDFJember Regency is one of the agro-industrial areas in Indonesia with a variety of activities that can produce noise including milling industry. Exposure to noise that is too strong or too long will damage the auditory nerve. The type of material being grounded determines the amount of noise produced so that the potential for hearing nerve damage also varies. This study aims to determine the level of noise produced by the milling industry and analyze the potential for hearing nerve damage in milling workers in Jember Regency. This type of research is observational analytic with cross-sectional approach. This research was conducted by measuring noise in several grinding locations in Jember that were randomly determined. Types of careful milling is grinding meat, coffee, rice, sticky rice and coconut. In addition to measuring the noise level, a short interview was also conducted with the mill workers regarding how long they worked at the mill every day. The measurement results are then analyzed descriptively and compared with standards set by the government and the Occupational Safety and Health Administration (OSHA). In this study it was found that the grinding of meat raw materials produced an average noise level of 88.5 db, coffee of 88.5 db, rice of 88.9 db, sticky rice of 87.3 db and coconut of 80.7 db. The duration of exposure to noise in milling meat, coffee, rice and sticky rice ranges from 9-12 hours a day. While the duration of noise exposure to coconut milling workers ranged from 6-9 hours. Therefore it can be concluded that milling meat, coffee, rice and sticky rice has the potential to cause hearing loss for workers.
Keywords: agroindustry, hearing loss, noisy, millin
Potential of Cocoa Extract (Theobroma cacao) in Inhibiting Erythrocyte Damage Induced by Physalia utriculus Venom
No full textPhysalia utriculus is one of the invertebrate marine biota that is often found in Indonesia. Some symptoms of venoming due to jellyfish stings cause pain, itching, and hemolysis. In Indonesia, 13 cases of jellyfish stings were reported in 2005-2009 with three people dying in Java, Bali, and Bangka. Cocoa beans (Theobroma cacao L.) contain fat, carbohydrates, proteins, and polyphenol compounds that are useful as antioxidants. Polyphenols in the form of epicathechins, catechins, and procyanidins serve to provide protection to hemolysis. The purpose of this study was to determine the potential of ethanol extract of cacao (Theobroma cacao L.) in inhibiting the damage of erythrocyte induced by Physalia utriculus in vitro. This study used 28 samples of erythrocytes divided into seven groups, namely the normal control group, negative controls, and treatment with cocoa ethanol extract 0.2%, 0.1%, 0.04%, and 0.02%. Each subsequent group induced venom Physalia utriculus. The results showed that the average speed of erythrocyte lysis in the treatment group by giving cocoa ethanol extract 0.2%, 0.1%, 0.04%, and 0.02% respectively (seconds ± standard deviation) was 858,25 ± 94,44; 1.000,5 ± 159,93; 678,5 ± 19,71; and 1.006 ± 159,50. The mean speed of erythrocyte lysis in the negative control group was 1,025 ± 164.63 and the positive control group with the administration of N-Acetylcystein can last up to one hour after administration of venoms. Test for normality and homogeneity shows that data is normally distributed and homogeneous. One Way Annova analysis shows the significance value of p <0.05, then a post hoc analysis test was performed with the Bonferoni method to find out the differences in significance in each group. In this study it can be concluded that the administration of cocoa ethanol extract has no potential to inhibit erythrocyte damage that has been venomed by Physalia utriculus in vitro.
Keywords: Physalia utriculus, cacao, erythrocyte damag
DNA Quality and Quantity on Blood Spot Post Soil and Ultraviolet-C Exposure
Get PDFBercak darah dapat ditemukan di tempat kejadian perkara (TKP) pada banyak kasus tindak kekerasan. Asam deoksiribonukleat (DNA) pada darah dapat digunakan sebagai data primer untuk proses identifikasi akan tetapi bercak darah di TKP berisiko rusak akibat pajanan tanah dan ultraviolet. Tujuan utama dari penelitian ini adalah untuk mempelajari efek kombinasi dari pajanan sinar ultraviolet-C dan tanah terhadap kualitas dan kuantitas DNA pada bercak darah. Sebanyak 20 gelas berisi 200 gram tanah ditetesi 900µl darah dan diberikan pajanan sinar ultraviolet-C dalam tiga kelompok berdasarkan durasi pajanan yakni satu hari, tiga hari, dan lima hari. Satu kelompok digunakan sebagai kontrol. Ekstraksi DNA dilakukan menggunakan DNAZol dilanjutkan dengan pengukuran spektrofotometri untuk mengetahui kualitas dan kuantitas DNA. Peningkatan konsentrasi DNA dapat diamati yaitu 681,1 pada hari pertama menjadi 1274,7 pada hari ketiga dan mulai menurun menjadi 1090,6 pada hari kelima, sedangkan kemurnian DNA terus menurun secara konstan seiring dengan meningkatnya durasi pajanan. Penelitian ini menunjukkan bahwa pajanan sinar ultraviolet-C dan tanah menyebabkan degradasi molekul DNA menjadi fragmen-fragmen molekul yang lebih kecil sehingga terjadi peningkatan kuantitas DNA yang disertai penurunan kualitas DNA. Penurunan kualitas DNA dapat mempersulit proses identifikasi sehingga isolasi DNA sampel pada tanah terbuka yang terpajan matahari harus dilakukan sesegera mungkin.
Kata Kunci: DNA, darah, tanah, ultraviolet C, patologi forensi
Potentials of Grinting Grass (Cynodon dactylon l.) For Biopesticides On Sitophylus Zeamais Motsch Mortality
Get PDFCorn is one of the cereals that has strategic and economic value and has the opportunity to be developed. The attack of the Sitophilus Zeamais Motsch species becomes one of the obstacles in the process of storing corn. This study aims to develop the potential of plant biopesticides from grinting grass to control the warehouse pests of Sitophilus Zeamais Motsch. This research is a laboratory based experimental study. The independent variables in this study were the gram weight of grinting grass extract and the number of Sitophilus Zeamais Motsch pests. The dependent variable in this study was the mortality of Sitophilus Zeamais Motsch. Grinting grass extract is obtained using maceration method. Qualitative and quantitative tests were carried out to test the active compound content of grinting grass. Vegetable biopesticide toxicity tests were carried out using a completely randomized design. The results showed that variations in the weight of grinting grass affect the content of chemical compounds present in the grass. Based on UV-Vis and FTIR spectra, the content of polyphenols, alkaloids, flavonoids, terpenoids, steroids, and saponins contains 20 gr / 100 mL, there are flavonoids as much, 2.38 mg / mL, saponins as 2.04 mg / mL, alkaloids as much as 1.79 mg / mL, polyphenols 3.15 mg / mL, steroids as much as 2.24 mg / mL and terpenoids as much as 3.15 mg / mL. Based on qualitative tests the active compound is evidenced by changes in color and deposition. While based on pest mortality tests, it was found that almost 50 percent of grinting grass extract can kill corn pests within a period of 7 days of observation with an extract concentration of 800 ppm.
Key words: Biopesticides, Grinting Grass, Uv-Vi
Correlation between Personal hygiene and Household Overcrowding to the Incidence of Pediculosis capitis in Sukogidri Village Jember
Get PDFAbstract
Pediculosis capitis is an infection of human hair or scalp caused by Pediculus humanus var. capitis. This disease is classified as a neglected disease and is quite developed in developing and poor countries. Risk factors that influence the incidence of pediculosis capitis is the level of education of parents, socio-economy, personal hygiene, age, gender, and household overcrowding. The purpose of this study was to determine the correlation between personal hygiene and household overcrowding to the incidence of pediculosis capitis in Sukogidri Village Jember. This study was an observational analytic study, with a cross sectional approach carried out on 230 respondents in Sukogidri Village Jember. In this study, head lice was examined using crescent combs, filling in personal hygiene questionnaires, and measuring the area of ​​respondent’s house. The results showed the prevalence of pediculosis capitis in Sukogidri Village was 44.3% (102 respondents). The results of data analysis using the fisher test and chi-square test showed that personal hygiene and household overcrowding had a significant relationship (p <0.05) as a risk factor for the incidence of pediculosis capitis in Sukogidri Village Jember.
Keyword : personal hygiene, household overcrowding, pediculosis capiti
Evaluation of CD4 Number In HIV / AIDS Patients Who Are Running The Antiretrovial Treatment Program
Get PDFHIV is a health problem for Indonesia and the world. Enforcement of diagnoses and control efforts continue to be made to reduce the number of HIV / AIDS cases. ARVs are becoming efforts to cure HIV by increasing CD4 cell counts. CD4 cell count is a determinant of ARV therapy. The purpose of this study was to evaluate CD4 cell counts in people with HIV / AIDS who were implementing ARV programs. The study design was observational using secondary data in the form of medical record records. The study population was HIV sufferers who registered to run an HIV / AIDS antiretrovial treatment program at the Cendana Poly Ngudi Waluyo Regional Hospital in Blitar in June 2017. Samples in the study were 30 people according to inclusion and exclusion criteria with a sampling technique using a purposive sampling method. Research instruments using questionnaires. Data analysis uses descriptive method. The results showed that this CD4 cell count had a CD4 cell count of 200 cells / mm 3 by 10%, 200-499 by 90% in patients who were on ARV programs. The patient's condition and obata resistance result in a CD4 cell count not exceeding 500 mm / cell.
Key words: amount CD4, ARV , patient HI