Jurnal Gizi Klinik Indonesia
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Asupan makan, status gizi, dan kualitas hidup pasien kanker payudara di RSUP DR Sardjito Yogyakarta
Get PDFBackground: Breast cancer is the fifth leading cause of death due to all the type of cancer and the second leading cause of death in developing country after lung cancer. The global incidents of this disease were 43%. The cancer cells have an ability to disturb the nutrients absorbtion in the body and give an effect of decreasing nutritional status, physical performance and quality of life.Objective: To show the relationship between nutrient intake, nutritional status and quality of life, breast cancer patients with radiotherapy at RSUP Dr Sardjito Yogyakarta.Method: This study was an observational study with cross sectional design. Total subject of this study were 85 respondents. Intake of energy, protein, fat and carbohydrate were measured using 1x24 hours food recall. Nutritional status were measured using patient-generated subjective global assessment (PG-SGA) questionnaire. Then the quality of life were measured using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) questionnaire.Results: There were significant difference in the average intake of energy (p=0.013), protein (p=0.043) and fat (p=0.016) between severe malnourished, moderate malnourished and wellnourished patients, whereas the average intake of carbohydrate was not significant (p=0.070). The lower nutrition intake, the lower nutritional status. There was also significant difference in fat intake (p=0.035) and nutritional status based on PG-SGA (p=0.002) between patients with poor and good quality of life. Patients with poor quality of life had lower nutrition intake and nutritional status.Conclusion: Nutrient intake gave an effect to nutritional status and quality of life in breast cancer patient with radiotherapy
The effect of Sea urchin (Diadema setosum) gonad extract on IgM and IgG antibodies production in BALB/c mice infected by Salmonella typhi
Get PDFBackground: Salmonella typhi infection decreases of the immune system and influences the adaptive antibodies among malnourished children. The gonad of Diadema setosum (D. setosum) is one of food sources from marine biota that contains high-quality nutrients and potentially can be used as a dietary supplement for typhoid fever condition.Objective: This study aimed to determine the effect of gonad D. setosum extract on the production of antibody IgM and IgG in an animal model.Method: This experimental study was used BALB/c mice before and after infected Salmonella typhi through intraperitoneally at 0.2 mL x the unit 103 CFU/mL. The level of IgM and IgG production was measured by Enzyme Linked Immune Sorbent Assay (ELISA). Experimental animals were divided into 2 groups. The control group was only fed with standard diets, while at the intervention group received the extract of D. setosum gonad in two doses (100 and 200 mg/kg body weight).Results: Production of IgM antibodies in the control group significantly increased twofold (p=0.001) whereas the intervention group received the extracts of D. setosum gonad (200 mg/kg body weight) could suppress the increase in IgM antibody production and indicate the highest increase of IgG antibody significantly (p<0.05) at day 7.Conclusion: The gonad of Diadema setosum extracts (200 mg/kg body weight) could suppress the increase in IgM antibody productions and indicate the highest increase of IgG antibody titers in mice infected with Salmonella typhi. The role of anti-microbial substances of the gonad of Diadema setosum, is potential to be utilized as dietary supplement to increase body immune system among patients infected by Salmonella typhi
Pengaruh durasi senam diabetes pada penurunan glukosa darah penderita diabetes mellitus tipe II
No full textBackground: The management of DM focused on four pillars: education, nutrition therapy, physical exercise, and pharmacological interventions. In type 2 diabetes, physical activity functions primarily in controlling diabetes.Objective: This study aims to determine the effect of differences in the duration of aerobic exercise on blood glucose levels.Method: This was quasi-experimental research with pre-post test design. A total of 24 respondents with type 2 diabetes were divided into two groups consisting of groups A that received aerobic exercise with a duration of 30 minutes and group B received aerobic exercise with a duration of 60 minutes for 6 weeks and frequency of exercise 3 times each week. Statistical tests use paired t-tests and independent t-tests.Results: The mean post-test blood sugar level based on HbA1c measurements in group A was 7.92±1.56% while group B was 7.13±0.99%. Mean pre-test - post-test blood sugar levels in the two groups were significantly different (p<0.05). Aerobic exercise for 6 weeks with a frequency of 3 times each week can reduce HbA1c by -2.5±0.96% in group A while group B increased by 0.02±0.29%. There is a significant difference in HbA1c before and after 6 weeks of aerobic exercise between two groups (p=0.021).Conclusion: Aerobic exercise with a duration of 30 minutes for 6 weeks 3 times each week can reduce blood glucose (HbA1c) by -2.5±0.96% while the group duration of aerobic exercise 60 minutes an increase of 0.02±0.29%. There is a significant difference in HbA1c before and after 6 weeks of aerobic exercise between the two groups
Karakteristik sosial demografi dan konsumsi zat besi pada ibu hamil berdasarkan data Studi Diet Total (SDT) tahun 2014 di Indonesia
Get PDFBackground: Pregnant women are the group most vulnerable to iron deficiency anemia. This occurs as a consequence of a significantly increased demand for iron intake during pregnancy. The efforts of pregnant women to compensate for the increased need of iron depend on various sociodemographic characteristics.Objective: To analyze the relationship between sociodemographic characteristics and iron consumption of pregnant women in Indonesia.Method: This research is observational study design with cross-sectional approach using secondary data of the Total Dietary Study (SDT) year 2014. A total of 644 pregnant women inform the SDT study who met our inclusion and exclusion criteria were assessed for their level of consumption using 24-hour dietary recall method. Data were then processed using Nutrisurvey software and Indonesian Food Composition Table (TKPI) to estimate the consumption of iron. Analysis was conducted using Mann-Whitney and Kruskal-Wallis tests by including various social demographic characteristics in pregnant women.Results: The results of this study found that level of education, employment status, economic status, and residence of pregnant women are significantly related to iron consumption (p<0.05).Conclusion: Pregnant women with high education, working status, middle to upper economic status, and living in urban areas have better iron consumption
Konsumsi ikan bersifat protektif terhadap diagnosis stroke pada orang yang pernah terdiagnosis hipertensi di Indonesia
Get PDFBackground: Stroke is a burdensome disease. The prevalence of stroke has increased by 16% over the last 6 years. The biggest risk factor for stroke is hypertension, but consumption of animal products such as meat, fish, eggs, and milk is often associated with the onset of stroke.Objective: To examine the relationship between the frequencies of animal products consumption to the incidence of stroke in 2014/2015 on hypertensive people in 2007/2008.Method: This research was using case control design performed by analyzing longitudinal data derived from Indonesian Family Life Survey (IFLS) 4 and 5 (2007/2008 and 2014/2015). The population of this study was Indonesian aged over 40 years who have been diagnosed with hypertension in IFLS 4.Results: The results of bivariate analysis using Chi Square test and Fisher's exact test found that the variables significantly associated with stroke diagnosis in IFLS 5 were IFLS 5 fish consumption (p=0.027; OR=0.47); IFLS 4 milk consumption (p=0.04; OR=2.97); IFLS 5 hypertension diagnosis (p=0.006; OR=4.03); IFLS 4 diabetes mellitus diagnosis (p=0.033;OR=8.91); and IFLS 5 diabetes mellitus diagnosis (p=0.041; OR=3.73), also IFLS 5 physical activity (p=0.00; OR=0.34).Conclusion: Fish consumption of 2 - 7 days per week and adequate physical activity is associated with a decreased risk of stroke in a population that has been diagnosed with hypertension. Daily milk consumption, hypertension diagnosis, and diabetes mellitus diagnosis may increase the risk of stroke
Latihan yoga terhadap berat badan, persen lemak tubuh, dan lingkar perut pada wanita dewasa overweight
Get PDFBackground: Obesity caused diabetes and cardiovascular disease. Yoga considered three aspects, physic, emotion and mental that helped in obesity therapy.Objective: This research aimed to explain the influence of yoga excercise on body weight, percent of body fat, waist circumference and waist to hip ratio (WHR) in overweight women.Method: This research applied quasi experiment design by using pre-post test with control group design. The subjects of research were 31 women aged 19-25 years old and divided into 2 groups, treatment group and control group. Treatment group was prepared to do yoga in 60 minutes for 10 times during 20 days and given nutrition education, whereas control group was given nutrition education only. Data body weight and percentage of body fat were measured by bioimpedance analysis; waist circumference and WHR were measured by tape measures; food intake were assessed by food recall and food frequency questionnaire. Data were analyzed using paired t-test and independent t-test.Results: There was a significant difference of body weight before and after intervention in both groups. The body weight on treatment group decreased by 0.81 ± 1.29 kg (p0.05). Conclusion: Obesity women with 10 times yoga had no significant influences on body weight, percentage of body fat, waist circumference and WHR
1,25 dihydroxyvitamin D dan kalsium pada akseptor depot medroxyprogesteron asetat (DMPA) berdasarkan lama pemakaian
Get PDFBackground: Long – term usage of depot medroxyprogesterone acetate (DMPA) may suppress estrogen levels causing the body to undergo hypoestrogenic. The hormone estrogen affects the metabolism of calcium and 1,25 dihydroxy vitamin D in the body. Calcium and 1,25 dihydroxy vitamin D are bone-forming vitamin and minerals.Objective: This study aimed to analyze the relationship between 1,25 dihydroxy vitamin D and calcium on the accelerate of DMPA based on long usage.Method: This is an observational study with cross-sectional design. A total of 70 acceporates sample was chosen by consecutive sampling and divided into 2 groups. 35 acceporates received DMPA for 1-2 years (group 1) and 35 acceporates received DMPA for 2-4 years (group 2). Serum 1,25 dihydroxy vitamin D levels examined by enzyme-linked immunoabsorbent assay (ELISA) method and serum calcium was quantified using the Calcium Arsenazo method. The research was conducted in Puskesmas Andalas and Lubuk Buaya Kota Padang between July 2017 and September 2017. The data normality was checked using Kolmogorov Smirnov and then the data were analyzed using the Spearman test.Results: The average of 1,25 dihydroxy vitamin D in group 1 is 351.16 pg/ml and in group 2 is 289.84 pg/ml. The median concentration of calcium on samples in group 1 is 9.30 mg/dl and in Group 2 is 9.13 mg/dl.Conclusion: There were negative significant correlations between 1,25 dihydroxy vitamin D and calcium in group 1 and group 2.
Pengaruh suplementasi zink terhadap parameter hematologi atlet sepatu roda setelah latihan endurance
Get PDFBackground: In sports such as roller skates, endurance can lead to increased inflammation and muscle cell damage, free radical formation, and zinc excretion from sweat and urine that affect the increased redistribution of zinc from blood to tissue. This mechanism causes a decrease in blood zinc levels, erythrocyte numbers and hemoglobin concentrations, increased leukocyte counts and the body’s oxidative stress parameters that have an impact on the athlete’s performance decline. Zinc supplementation may be given to maintain the athlete’s hematologic parameters during endurance exercise.Objectives: To examine the effect of zinc supplementation on serum zinc level, hemoglobin concentration, erythrocyte and leukocyte counts, and blood MDA level of skate athletes after endurance exercise.Method: This study was an experimental clinical trial using pre and post-test designs on 8 athletes incorporated in the pre-PON DIY Wheels Team. The study was conducted in two periods, one week of endurance exercise without zinc supplementation and one week of endurance exercise with 30 mg/d of zinc supplementation. Blood sampling was performed on the seventh day of each period, before and after endurance training.Results: There was a decrease in erythrocytes and hemoglobin concentration, and a significant increase in leukocyte count after endurance training in both periods (p0.05). Although there were no significant differences in all athlete hematologic parameters between two treatments (p>0.05), there was an improvement in serum zinc levels, hemoglobin concentrations, erythrocyte, and leukocyte counts.Conclusion: Zinc supplementation 30 mg/day for one week did not have a significant effect on the athlete’s hematology parameters after endurance exercise
Kekuatan genggam tangan, skor Child Pugh, dan massa otot pada pasien dengan sirosis hati
Get PDFBackground: Malnutrition is independent factor related to morbidity, mortality and high cost of treatment in liver cirrhosis. Hand grip strength (HGS) is one of the method use for malnutrition detection and prognosis evaluation. The correlation of HGS with liver function (Child Pugh score) and muscle mass is controversial. These important evaluation is not yet avalaible in Indonesia.Objective: Aim of this study is to assess the role of HGS measurement in malnutrition and its correlation with liver function and muscle mass.Method: This is a cross-sectional study in liver cirrhosis patients at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital from February to June 2015. Nutritional status was assessed by HGS. Muscle mass was obtained from bioimpedance. Data were analyzed using Spearman correlation test.Results: There were 115 patients liver cirrhosis at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital, 112 patients who fit the inclusion criteria, consisted of 79 men and 33 women with mean age 54.15±10.55 years, median Child Pugh score 6 (5-13) with median HGS 26 (11-50) kgF, mean muscle mass 44.43±8.12 kg. The median intake of energy 1334.82 (604.75-3023.7) kkal, median protein 45.87 (19-114.5) gram. Prevalence of malnutrition according HGS was 33%. Hand grip strength is not correlated with Child Pugh score (p=0.046; r=-0.19) however it is correlated with muscle mass (p<0.00; r=0.70).Conclusion: There are 33% malnutrition cases based on HGS in out patient liver cirrhosis. There is no correlation between HGS with Child Pugh score however HGS is correlated with muscle mass in liver cirrhosis
Efek kombinasi vitamin B1, B6, B12 untuk menurunkan intensitas nyeri pada penderita neuropatik diabetes
Get PDFBackground: Neuropathy diabetic pain are common symptom in patient with diabetic melitus. The combination of vitamin B1, vitamin B6, and vitamin B12 usually used for treatment the pain, the result of previous studies are limited and conflicting.Objective: The aim of the study to measure the convering of intensity of pain in diabetic neuropathy.Method: The method of study using quase experimental design with pre and post treatment patient were selected by conservative sampling method from Bethesda Hospital, Yogyakarta. There are 68 patient diabetic neuropathy to follow in the study. Fact patient received combination of vitamin B1 100 mg, vitamin B6 100 mg, and vitamin B12 5000 mcg once a day for 3 month. Pain intensity measured using visual analog scale (VAS) on the first initial visited after 30th day and 90th day.Results: The 68 patient consist of 27 (39.7%) male and 41 (60.3%) women. The mean age 58.32±6.72 years. The mean duration of Diabetic 4.32±2.86 year. The study showed that the pain intensity lower significantly after received vitamin B (p<0.001). The mean pain intensity in first VAS 43.68±12.32 lower to 20.42±11.24 and in the end of study lower to 12.23±8.39.Conclusion: The combination of vitamin B1, B6, B12 significantly lower pain intensity of patient diabetic neuropathy