Jurnal Gizi Klinik Indonesia
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    Efek asam alfa lipoat terhadap insulitis pada tikus diabetes melitus tipe 2

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    Effect of alpha lipoic acid on insulitis in type 2 diabetic ratBackground: The damaging of β cell causes hyperglycemia. Β cell damaged as insulitis happens because of the increase of free radical and the decrease of endogen antioxidant that caused oxidative stress.Objective: The goal of this research was to find out the effect of alpha lipoic acid (ALA) on pancreas Langerhans island’s histopathology in type 2 diabetic rats.Methods: This was an experimental laboratory study with post test only design. Fifteen adult male rats of  Wistar strain were segregated into three groups (n=5) labeled as control, type 2 diabetes (DM), and DM+ALA. The experiment was designed for 3 weeks. The measured parameter was insulitis level on pancreas Langerhans island of groups labeled.Results: The statistical test result showed there was the significant difference between control and type 2 diabetes group (p=0,005), but there was no significant difference between DM and DM+ ALA group (p=0,549).Conclusions: Although not statistically significant, giving ALA 60 mg/kg body weight for 3 weeks decreased the degree of insulitis in diabetic rats

    Pola konsumsi atlet sepakbola remaja di Indonesia

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    Consumsion pattern of football athlete in IndonesiaBackground: Some early research shows that nutrition in adolescent soccer athlete is still less than the recommended requirements. In Indonesia itself is still lack of studies that describe the pattern of consumption of teenage football athlete.Objective: Describe the consumption pattern in Indonesia teenage football athlete.Method: is study is an observational study at soccer boarding school in Jakarta and Malang. The subjects involved 131 athletes with age 15-19 year. This research conduct on February – May 2016. Researchers examined the intake of food the subject inside the hostel and outside the hostel with 3x24 hour food recall and semi quantitative food frequencies method. Fulfillment nutrient intake of the subject compared with the standard requirements Nutrition Adequacy Score ( AKG 2013) according to age groups.Results: The intake of macro nutrients include energy and carbohydrate was significantly lower than recommendation (p <0.000), whereas protein intake beyond the amount recommended (p <0.000). A total of 33.6% of the subjects taking the supplement with varying types. Types of supplements most consumed supplements vitargo electrolyte (18 people), followed by multivitamins and vitamin C (15 people), calcium (13 people), and herbal supplements (9 people).Conclusion: The consumption pattern teenage soccer athletes for energy and carbohydrate nutrition recommendations do not meet the standards when compared with the needs and AKG 2013. Provision of education needs to be done to improve intake patterns athletes, so the nutritional needs can be met to get the physical quality and the best performance

    Lingkar pinggang dan lingkar leher dengan kadar kolesterol total pada wanita usia subur obesitas

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    Waist circumference, and neck circumference correlated to total cholesterol among reproductive-age women with obesityBackground: Dyslipidemia is a metabolic disorder condition that is closely related to cholesterol and obesity. The prevalence of obesity in reproductive-age women (>18 years) in Indonesia increased dramatically. Reproductive age women with obesity are at greater risk of hypercholesterolemia compared with non-obese. Waist circumference (WC), mid-upper arm circumference (MUAC), and neck circumference (NC) can be used as a marker of higher or low cholesterol levels. Objective: This study aimed to determine the relationship between WC, MUAC, and NC with total cholesterol. Methods: The study design was cross-sectional with several subjects were 54 women of reproductive-aged 18-29 years. Subject with obese category (BMI ≥25kg/m2) was measured the WC, MUA, and NC as an independent variable and total cholesterol as the dependent variable, and dietary intake (total fat, cholesterol, and saturated fat) as confounding variables. The bivariate analysis used the Pearson correlation test. Multivariate analysis used multivariate linear regression. Results: Bivariate analysis showed there was a significant relationship between WC and NC to total cholesterol (p=0.006 and p=0.001), but not on MUAC (p=0.063). In multivariate analysis, NC is the most significantly related to total cholesterol (β=0.367; p=0.004; Adjusted R Square 24%) than WC. Conclusions: There is a significant relationship between WC and NC to the total cholesterol in women of reproductive age obesity. NC more significantly related to total cholesterol

    Peran kecambah kacang hijau (Phaseolus radiatus (L.)) pada sel lemak retroperitoneal tikus Sprague Dawley yang diberi diet tinggi lemak

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    The role of mung bean sprouts (Phaseolus radiatus (L.)) on retroperitoneal fat cells of Sprague Dawley rats fed a high-fat dietBackground: The tendency of current lifestyles with high consumption patterns of fat is one of the factors causing obesity which is a risk of cardiovascular disease. Prevention of cardiovascular disease can be done by adopting a dietary pattern that is rich in antioxidants including consumption of sources of vitamin E. Sprouts from mung beans contain vitamin E and phytochemicals rich in antioxidants, so they can be used as an alternative to prevent hyperlipidemia sourced from daily functional food.Objective: To assess the effects of mung bean sprouts on retroperitoneal fat weight, cell number and cell diameter in rats fed high-fat feed.Method: This research is an experimental study with a post-test design with the control group. Thirty-four male Sprague Dawley rats ± 2 months old were divided into five groups, group I (standard feed), group II (high-fat feed), group III (high-fat feed and intervention of feeding tube of mung bean sprout 0.67 g/ 200 g BW), group IV (high fat feed and intervention of feeding tube of mung bean sprout 1.34 g / 200 g BW), and group V (high-fat feed and 23 IU dose of vitamin E supplement with feeding tube). After adaptation for three days, the intervention was carried out for four weeks. Analysis of fat weight, fat cell number, and fat cell diameter were done after the treatments. Data analysis using the One-Way ANOVA test. Results: Mung bean sprout dose of 1.34 g given for 4 weeks did not significantly decrease fat weight and cell number, but it decreased the diameter of retroperitoneal fat cells.Conclusion: Mung bean sprouts dose 1.34 g was better than a dose of 0.67 g and vitamin E supplementation in reducing the diameter of retroperitoneal fat cells in rats fed a high-fat diet

    Kepatuhan konsumsi suplemen mikronutrien tidak terpengaruh oleh bentuk suplemen

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    Compliance of micronutrients supplement consumption was not affected by supplements formBackground: Taburia is micronutrient sprinkle produced by Ministry of Health Indonesia to overcome malnutrition problem in Indonesia. Compliance of Taburia consumption is an important indicator for the success of the supplementation program. Taburia’s compliance in some regions is low (0.05). Several factors affected the compliance level such as mother’s employment status, gender of the children, and age of the children. Conclusions: The compliance level of Taburia sprinkle and fortified gummy candies was similar. Hence fortified gummy candies could be used as an alternative of micronutrient supplement to overcome nutrition problem in Indonesia

    Status iodium pada anak usia sekolah berdasarkan ekskresi iodium urin dan asupan iodium

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    Iodine status in school-age children determined from iodine urine excretion and iodine intakeBackground: School-age children are more at risk if they experience deficiencies and excess iodine. The concentration of iodine in urine is a good biomarker for assessing iodine intake, 90% of iodine intake will be excreted through urine. Objective: This study aimed to analyze the iodine status of school-age children based on urinary iodine excretion (UIE) and iodine intake.Method: The study design used a cross-sectional study on 44 healthy school-aged children in Bogor Regency. Subject selection was done purposively in healthy 5th-grade elementary school students. The data taken in this study was urine iodine excretion concentration and food recall (1x24 hours). Data were analyzed using descriptive analysis and Pearson correlation test.Results: Median iodine excretion concentration in urine was 157 μg/l and the average daily iodine intake of children was 83.29 mg/day. Conclusion: The concentration of iodine excretion in the urine of the children is in the category of sufficient iodine as recommended by WHO / UNICEF / ICCID while the daily intake of iodine for children is still in the less category. The results showed that there was no association of iodine daily intake with iodine excretion concentration in urine(p=0.469)

    The effect of lesser yam based cookies on fasting glucagon-like peptide 1, appetite, and dietary intake in overweight/obese with ad libitum diet

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    Background: Appetite and dietary intake have been associated with obesity and successfulness of weight loss in obese individuals. Glucagon-like peptide 1 is a gut-derived neuropeptide that is produced as a response to dietary intake and associated with appetite. It has been investigated that prebiotic can induce GLP-1 production in animal models and humans. Objectives: This study aimed to investigate the effect of lesser yam based cookies on fasting GLP-1 plasma, appetite, and dietary intake. Methods: An experimental study was conducted on 15 overweight/obese individuals using cookies made with lesser yam flour for 6 weeks. Fasting GLP-1 level, dietary intake, and appetite were measured before and after the intervention. Dietary intake was recorded using a semi-quantitative food frequency questionnaire and appetite was measured using a visual analog scale. Results: After the intervention, the dietary intake includes total energy (p=0,013), protein (p=0,004) and carbohydrate (p=0,02) were significantly reduced. Based on paired t-test that was done in each time point, after the intervention subjects had lower hunger feeling and higher satiety especially at 4 (p=0,039) and 3 (p=0,039) hours after breakfast, respectively. Fasting GLP-1 plasma level was not changed after the intervention (p>0,05). There is no correlation between GLP-1 and dietary intake as well as appetite. Conclusions: We concluded that lesser yam based cookies were able to reduce dietary intake and hunger as well as increase fullness. The fasting GLP-1 concentration did not change after the intervention this was not associated with changes in satiety, fullness, desire to eat, or energy intake

    Pengetahuan, sikap, motivasi ibu, dan praktik pemberian MP-ASI pada anak usia 6-23 bulan: studi formatif di Aceh

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    Maternal knowledge, attitude, motivation and complementary feeding practice of children aged 6-23 months: formative study in AcehBackground: Poor knowledge, attitude, and motivation of the mother determine complementary feeding (CF) practice of the child resulting in poor nutrition fulfillment. Objective: This study aimed to analyze maternal knowledge, attitude, motivation, and relationships with the CF practice of children aged 6-23 months.Method: A cross-sectional study and cluster random sampling was applied to select 392 mothers of children aged 6-23 months in Aceh Besar District. Data on maternal knowledge, attitude, and motivation were collected using valid and reliable structured questionnaire. CF practice quality was assessed using indicators of timely introduction to CF, minimum meal frequency, minimum dietary diversity, and minimum acceptable diet according to WHO recommendation. The association of maternal knowledge, attitude, and motivation with CF practice was analyzed using binary logistic regression with a 95% confidence level (α=0.05).Results: There was a small proportion of mothers (20.2%, 8.7%, 33.9%) having good knowledge, attitude, and motivation, respectively. Overall, there was one-fourth (23%) of the children aged 6-23 months receiving CF as recommended by WHO. There were significant correlations between maternal knowledge and attitude (r=0.606, p<0.01) and motivation (r=0.103, p<0.05). Education level and motivation were the risk factors of improper CF practice (OR=4.25; 95% CI: 1.10-16.36; p=0.035and OR=1.83; 95% CI: 1.05-3.16; p=0.031, respectively). Conclusion: Maternal knowledge, attitude, and motivation of children aged 6-23 months in Aceh were still poor, shown by improper CF practice. Therefore, an effort to improve nutrition education, particularly by health personnel and stakeholder, to be specific and targeted is important.

    Pemantauan gizi dengan SMS reminder efektif meningkatkan kepatuhan diet pasien hemodialisis

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    Nutritional monitoring with SMS reminder is effective to increase the dietary compliance of hemodialysis patientsBackground: Patients with routine hemodialysis are at risk of malnutrition, inadequate intake of protein, hypoalbuminemia, gastrointestinal disorders. One of the factors affecting dietary compliance is knowledge so that the education and nutrition monitoring on an ongoing basis is necessary. Objective: To determine the effectiveness of nutrition monitoring with SMS reminders on dietary compliance of hemodialysis patients.Methods: This was a quasi-experimental study that involved 30 regular hemodialysis patients, divided into two groups. The inclusion criteria were aged >18 years, willing to become respondent and following the procedure, have a handphone, able to read and write. Patients with anasarca edema and complications of malignancy disease were excluded. The independent variable is nutritional monitoring with SMS reminders, while the dependent variable is dietary compliance. Data were statistically analyzed using the Chi-Square test and multiple logistic regression test. Results: Statistical analysis showed that nutritional monitoring with SMS reminder effectively influences the compliance on the consumption of energy (p=0.011, RR=2.750), fluid (p=0.014, RR=2.000), and potassium (p=0.011, RR=2.750). The compliance on the consumption of fluid is the most dominant factor affected by nutrition monitoring with SMS reminders given (B=3.676, p=0.02).Conclusions: Nutritional monitoring with SMS reminders is effective to increase the dietary compliance of hemodialysis patients

    Kondisi stres pada karyawan mempengaruhi tingkat konsumsi gula sederhana dan natrium

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    Stress in work staff influenced simple sugar and sodium intakeBackground: Stress is a condition that occurs to individual experiences a burden of a problem that can not solve there for lead to an unspecific response from the body. One of the causes of stress is the load of work. Stress caused by work could lead to obesity, cardiovascular disease, and diabetes. Change of behavior during stress like eating behavior cause of changing appetite on the individual.Objective: This research was aimed to analyze simple glucose and sodium intake during stress in staff.Method: This was a cross-sectional research design. A total of 125 subjects were chosen by purposive random sampling. The subject was the educational staff of Universitas Ahmad Dahlan. Data was collected as identity, nutrition intake used the Semi-Quantitative Food Frequency Questionnaire (SQFFQ), and stress level used Depression Anxiety Stress Scales (DASS) questionnaire. The statistical test used the Chi-Square test.Results: There is no significant difference between a simple sugar and sodium intake to stress level (p>0.05). The average of simple sugar and sodium intake classified as normal as much as 56.49±77.20 g for simple sugar intake and as much as 653.30±464.55 mg for sodium derived from food ingredients added salt and preservative foods. Data characteristic showed that the nutritional status of 40,8% of the staff was overweight and obese. Conclusions: There is no significant difference between stress level and simple sugar and sodium intake.

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