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    Research for Dropout Prevention Using FIDO2 Authentication Server: From Aspect of Correlation Between Poor Attendance and Dropout Rate

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    FIDO2標準は, クレデンシャルをユーザとサーバーで共有しないことから, 安心・安全な認証環境 を構築できることで知られる. 本論文においては, 城西大学が独自に実装したFIDO2アプリケーション・サー バーによるパスワードレス環境において, なりすましのできない出席管理システムが退学者防止効果に与える影 響ついて, 出席不良者と退学率相関関係の視点にて分析を行った. 分析の結果,「1年生の退学率・退学者数が最 も多いこと」「リモート対応の中, 退学につながる可能性のある「出席不良者」の確認対応に改善必要性があるこ と」を確認し, FIDO2サーバーの活用は, こうした学生の退学者防止に一定の効果がある可能性があることを確 認した.FIDO2 standard is known as a safe and secure authentication protocol since it does not share users’ credentials between server and user. In this paper passwordless environment achieved by the FIDO2 application server Josai University implemented is effective for non-spoofing attendance management, and leads to dropout prevention. An analysis was made to find correlation between poor attendance and dropout rate. We found poor attendance management should be improved since freshmen’s dropout rate is higher than others and poor attendance rate is higher at hybrid classes

    Effect of bone mass on the relationship between bone metabolism related genes and lifestyle in young Japanese women

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    最終的に被検者数は500名となった。5つのビタミンD受容体遺伝子多型のうち、Cdx2遺伝子型はカルシウム摂取量との相互作用により骨量に有意な差が認められた(Nutrient, 2020)。さらに、BMIで調整を行ってもBsmI、TaqI遺伝子型において骨量と遺伝子型に有意な差が認められ、BsmI、TaqI、ApaI遺伝子型もカルシウム摂取量との相互作用により骨量に有意な差が認められた(BMC Women's Health, 2021)。本研究により、ビタミンD受容体の遺伝子型はカルシウム摂取量と相互作用を示し、若年女性の骨量に影響を与えることが明らかとなった。Eventually, the number of subjects reached 500. Of the five vitamin D receptor gene polymorphisms, the Cdx2 genotype was found to have a significant difference between dietary calcium intake and bone mass (Nutrient, 2020). Furthermore, bone mass was significantly different among the BsmI and TaqI genotypes after adjusting for body mass index (BMI). The BsmI, TaqI and ApaI genotypes showed significant differences in bone mass between the calcium-intake groups (BMC Women's Health, 2021). These findings revealed that the genotype of vitamin D receptors interacts with calcium intake and affects bone mass in young women.科学研究費助成事業研究成果報告書 研究種目:若手研究, 研究期間:2018~2021, 課題番号:18K17938 研究分野:食品科学, 研究者番号:60815281. 6p

    Mathematical Bulletin of the Graduate School of Science Josai University 24

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    Cell proliferation effects of S-allyl-L-cysteine are associated with phosphorylation of janus kinase 2, insulin-like growth factor type-I receptor tyrosine kinase, and extracellular signal-regulated kinase 2 in primary cultures of adult rat hepatocytes

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    The cell proliferation effect of S-allyl-L-cysteine (SAC) and its mechanisms were examined in primary cultures of adult rat hepatocytes. In serum-free cultivation, SAC (10−6 M)-stimulated hepatocytes showed significant proliferation compared to control at 5-h culture; the effect was dependent on the culture time and the dose of SAC (EC50 value 8.58 × 10−8 M). In addition, SAC-stimulated hepatocytes significantly increased mRNA expression levels of c-Myc and c-Fos at 1 h and cyclin B1 at 3.5 and 4 h, respectively. In contrast, alliin and allicin, structural analogs of SAC, did not show these effects observed with SAC. The SAC-induced hepatocyte proliferation effects were completely suppressed by monoclonal antibodies against growth hormone receptor and insulin-like growth factor type-I (IGF-I) receptor, respectively. Furthermore, the Janus kinase 2 (JAK2) inhibitor TG101209, phospholipase C (PLC) inhibitor U-73122, IGF-I receptor tyrosine kinase (RTK) inhibitor AG538, PI3 kinase inhibitor LY294002, MEK inhibitor PD98059, and mTOR inhibitor rapamycin completely suppressed the SAC-induced hepatocyte proliferation. JAK2 (p125 kDa) phosphorylation in cultured hepatocytes peaked 5 min after SAC stimulation. SAC-induced IGF-I RTK (p95 kDa) and ERK2 (p42 kDa) phosphorylation had slower rises than JAK2, peaking at 20 and 30 min, respectively. These results indicate that SAC promoted cell proliferation by growth hormone receptor/JAK2/PLC pathway activation followed by activation of the IGF-I RTK/PI3K/ERK2/mTOR pathway in primary cultures of adult rat hepatocytes.Article No.17506

    Computer exercises on a mathematical model of infectious diseases– Simulation with computer algebra software Maple –

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    理学部数学科の2 年次専門選択科目「数式処理による解析」の中で,SIR モデルの解説と数式処理ソフトMaple を用いたシミュレーションを行ったので紹介する。SIR モデルは感染症の流行を記述する連立微分方程式で,SIR モデルおよびこれを基本とする数理モデルが新型コロナウイルス感染症の流行分析や予測においても用いられている。報告 / Report

    Sports wagashi development project using local resources through high school-university agricultureindustry collaboration - Development of the regional collaboration product “JOSAI Collagen Yokan“

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    地域活動ノート / Notes 編集:城西大学・城西短期大学地域連携センター紀要編集委員

    Possibility of the online volunteer Change in the information society

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    The COVID-19 pandemic (hereinafter the “Pandemic”) has made many things impossible, with it becoming difficult for people to meet and talk with each other face to face since not meeting people per se lowers the risk of infection. Many volunteer activities had to be suspended as well. The educational effects of volunteer and community events are very significant; therefore, we can not blame the lack of anything on the Pandemic. For this reason, we have come up with the idea of online volunteering. While it is obviously not the same as volunteering in person, it is necessary to stay connected with people especially in this day and age with increasing loneliness and isolation. Volunteering is a way for people to talk directly to each other and build relationships as they help each other. Therefore, we would like to consider the possibility of online volunteering.論文 / Article 編集:城西大学・城西短期大学地域連携センター紀要編集委員

    Annual Report 2021

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    編集:城西大学・城西短期大学地域連携センター紀要編集委員

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