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    Birth of “OKUMUSASHI”

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    The name “OKUMUSASHI” is presumed to have been created by MUSASHINO Railway. In the early days, HANNO area was called “OKUMUSASHINO”. When MUSASHINO Railway extended to AGANO, “OKUMUSASHI” changed from HANNO area to AGANO area. And the bus service to CHICHIBU expanded the area of “OKUMUSASHI”. Mountaineers and hikers have expanded the area of “OKUMUSASHI” to include mountains along TOBUTOJO Line. In 1951, “SAITAMA Prefec tural OKUMUSASHI Nature Park” was established. The area of “OKUMUSASHI” was limited to the area along SEIBU Railway.査読論文 / PeerReviewed Article 編集:城西大学・城西短期大学地域連携センター紀要編集委員

    The Memorandum of Intermediate Organizations, Publicness, and Institutions in the Information Society : Thinking about the Information Society in the Face of New Coronavirus(COVID-19)Problem in 2020

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    本稿は,情報化社会における中間組織と公共性,そして制度に関する「覚え書き」として,まずベラーらが著した『善い社会』での論点を参照しながら従来の議論を振り返り,今後の課題を整理した。次いで,2020年の新型コロナウイルス感染症(COVID-19)問題は制度の変容を考える上で格好の事例を提示していることから,筆者らが所属するそれぞれの職場でのコロナ禍への対応や業界の変化について,中間組織,公共性,制度をキーワードに検討した。その結果,既存の中間組織が機能不全に陥っていることが今回のコロナ禍によってより鮮明になったこと,コロナ禍をきっかけとした様々な変化の方向性が「善い社会」に向かうか否かは不透明であるが,「善い社会」に向かうためにはそれぞれの中間組織が主体的に関与していく必要があること,そして「大きな社会」で民主主義を実現していくためには,中間組織を介して異種の制度の間に活発な対話を生み出すこと,を結論として述べた。This study first reviewed conventional arguments on intermediate organizations, publicness, and institutions in the information society, referring to points at issue in Robert N.Bellah et al.'s The Good Society, and examined future tasks. This study next investigated a)countermeasures against the 2019 novel coronavirus(COVID-19)calamity at each workplace to which the authors belonged and b)the changes in industries using intermediate organizations, publicness, and institutions as keywords because problems with the COVID-19 infection in 2020 present suitable cases for examining institutional change.Consequently, the COVID-19 calamity revealed that existing intermediate organizations became dysfunctional in their failure to respond. Although it was unclear whether the direction of various changes triggered by the COVID-19 calamity was toward the "good society," each intermediate organization must independently participate in the corresponding change in order to achieve the "good society." To realize democracy in the "big society," active dialogue among different types of institutions must be created through intermediate organizations.論文 / Article

    ANNALS of Josai Graduate School of Economics

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    A Report on Online Chinese Classes : The Case of Josai University, 2020

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    報告 コロナ禍における授業 / Reports on Some Styles of Classes under the COVID-19 Calamit

    Representations of Discrete Groups and Geometric Topology on Manifoldss, Josai University

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    Representations of Discrete Groups and Geometric Topology on Manifoldss, Josai University

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    The 4n + 3-dimensional quaternionic Heisenberg nilpotent Lie group M admits a quaternionic contact structure. There exists a three dimensional simply connected non-abelian solvable Lie group R acting properly on M. We show that the quotient of M by R admits a quaternionic almost Hermitian metric g. Moreover, one almost complex structure, say J from the quaternionic structure is shown to be integrable for which (M/R,J) is a Bochner flat K¨ahler manifold

    Josai Teacher-Training Course Center Review

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    Looking Back on the 2020 Online classes in the Department of Chemistry, Faculty of Science

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    特集 / Feature

    Stimulation of the Runx2 P1 promoter by collagen-derived dipeptide Prolyl-hydroxyproline bound to Foxg1 and Foxo1 in osteoblasts

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    学位授与機関:城西大学 学位記番号:博甲第101号,学位の種別:博士(薬科学), 学位授与年月日: 令和3年(2021年)3月17日 (91p.)博士(薬科学)城西大

    Effect of Lactic Fermentation Products on Human Epidermal Cell Differentiation, Ceramide Content, and Amino Acid Production

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    Introduction: Lactic fermentation products (LFPs) are thought to affect “good” bacteria in the gut. We previously reported that oral administration of LFPs has beneficial therapeutic effects in a mouse model of atopic dermatitis. However, it is unclear how LFPs affect human epidermal cell differentiation, ceramide (Cer), and amino acid production. Objective: The aim of this study was to determine the effects of LFPs on epidermal cell differentiation, by assessing amino acid and Cer production. Methods: A 3-dimensional cultured human epidermis model and normal human epidermal keratinocytes were used. Cytotoxicity tests were performed using alamar Blue. Transepidermal water loss (TEWL) was used as an index to assess barrier function. Keratin 1 (K1), keratin 5 (K5), keratin 10 (K10), involucrin (INV), calpain 1, and transglutaminase (TGase) (markers of differentiation) and profilaggrin (proFLG) and bleomycin hydrolase (amino acid synthesis-related genes) expression levels were quantified by RT-PCR. In addition, TGase protein levels were measured by Western blotting. The intercellular lipid content of the stratum corneum was measured by high-performance thin-layer chromatography. Amino acids were quantified using an amino acid analyzer. Finally, bound water content in the stratum corneum was measured by differential scanning calorimetry. Results: Cell viability did not change, but TEWL was significantly decreased in the cells treated with LFPs compared with the control cells. Treatment with LFPs significantly increased expression of the late-differentiation markers INV and TGase at the RNA level. Furthermore, TGase protein expression was significantly increased by treatment with LFPs. Treating a 3-dimensional cultured epidermis model with LFPs significantly increased the intercellular lipid content of the stratum corneum and production of the amino acid arginine (Arg). The amount of bound water in the stratum corneum was increased significantly in the LFP application group. Conclusion: Treatment with LFPs promotes human epidermal cell differentiation and increases the intercellular content of the free fatty acid, Chol, Cer [NS], Cer [AS], and Cer [AP]. This may result in improved skin barrier function. The increased amount of Arg observed in keratinocytes may help improve water retention

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