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ISOLATION OF ANTIOXIDANT COMPOUNDS OF METHANOL EXTRACT OF NUTMEG LEAVES (Myristica fragrans Houtt)
Get PDFAbstract.The antioxidant activity from methanol extract of nutmeg leaves (Myristica fragrans Houtt) was performed using 2,2-diphenyl-1-picrylhydrazil (DPPH). Antioxidant assay using DPPH of the methanol extract at a concentration of 25 ppm, 50 ppm and 100 ppm, showed high antioxidant activity with IC50 = 36.31 ppm and Vitamin C showed antioxidant activity with IC50 = 3.657 ppm. The methanol extract of nutmeg leaves were partitioned with chloroform to obtain chloroform extract of the leaves with IC50 = 28.30 ppm. isolation of the active compounds from the chloroform extract of the nutmeg leaf using column chromatography yielded 6 mix fractions MFMD 1, MFMD 2, MFMD 3, MFMD 4, MFMD 5 and MFMD 6. The test results of antioxidant activity in very strong category is fractions MFMD 4, MFMD 3, MFMD 2, MFMD 6 and MFMD 5 with IC50 of each are 26.590 ppm, 27.239 ppm, 29.639 ppm, 39.766 ppm and 55.436 ppm, while antioxidant activity in a weak catagory is fraction MFMD 1 with IC50 is 126.270 ppm. This shows that the fraction of the leaf has a better inhibitory activity, because some of the active compound contained in the fraction can synergize in inhibiting free radicals, so that the IC50 value of the fraction is stronger than the extract.Keywords: Antioxidant, chromathography, Nutmeg (Myristica fragransHoutt), methanol extract, leave
DETERMINATION OF VITAMIN C IN SEVERAL VARIETIES OF MELON FRUITS BY TITRATION METHOD
Get PDFAbstract. Vitamin C (ascorbic acid) is micronutrient that is water soluble and indispensable for the body's metabolism, also plays a role in immune function. Vitamin C are easy to be absorbed actively. One of the fruits that contain vitamin C is melon fruit. Many varieties of melon fruit affect the vitamin C levels. The levels of vitamin C can be determined by 2,6-dichloroindophenol titration method using 2,6-dichloroindophenol solution. The advantages of the 2,6-dichloroindophenol titration method in the determination of vitamin C levels is reductor substances other than vitamin C are not oxidized by 2,6-dichloroindophenol. The examination begins with the determination of equivalence of 2,6-dichloroindophenol solution to vitamin C and followed by determination of vitamin C levels in several varieties of melon fruit. Equivalence of 2,6-dichloroindophenol solution to vitamin C was obtained 0,1347 mg vitamin C per 1 mL 2,6-dichloroindophenol solution. Levels of vitamin C in various varieties of melon fruit obtained that the highest levels was in Golden Melon variety (9,209 mg vitamin C per 100 g of Golden Melon) while the lowest levels was in Langkawi Melon variety (0,335 mg of vitamin C per 100 g of Langkawi Melon). It can be concluded that vitamin C levels contained in melon fruit vary and depend on melon fruit varieties.Keywords: Vitamin C, Ascorbic Acid, Melon Fruits, Varieties, Titration MethodREFERENCES. Almatsier, 2001, Prinsip Dasar Ilmu Gizi, Gramedia Pustaka Utama, Jakarta, 152-153, 185-186.F. Prajnanta, 2003, Melon: Pemeliharaan secara Intensif dan Kiat Sukses Beragribisnis. Penebar Swadaya, Jakarta, 3, 30.R. Rukmana, 2007, Melon Hibrida, Kanisius, Yogyakarta, 11, 13-15, 16.B. Samadi, 2007, Melon: Usaha Tani dan Penanganan Pascapanen, Kanisius, Yogyakarta, 19, 23, 25-28, 31.P.M. Wijoyo, 2009, Panduan Praktis Budi Daya Melon, Bee Media Indonesia, Jakarta, 14-17, 55.I.G. Gandjar, dan A. Rohman, 2007, Kimia Farmasi Analisis, Pustaka Pelajar, Yogyakarta, 249.N. Andarwulan, dan S. Koswara, 1992, Kimia Vitamin, Rajawali Press, Bogor, 14-20, 32-35, 235.Direktorat Jenderal Pengawasan Obat dan Makanan Departemen Kesehatan Republik Indonesia, 1995, Farmakope Indonesia, Edisi Ke-4, Departemen Kesehatan Republik Indonesia, Jakarta, 1215-1216.W. Horwitz, 2002, Official Methods of Analysis of Association Offical Analytical Chemist Internasional, Edisi Ke-42, Association Offical Analytical Chemist International Suite, Maryland, 16-17.10. J.N. Counsell, and D.H. Hornig, 1981, Vitamin C, Applied Science Publisher, London, 123-124.11. R.M. Astrid, 2016, Cara Cerdas Berkebun Emas Dengan Menanam Melon, Villam Media, Depok, 67
SEMI-IMPLICIT NUMERICAL SCHEMA IN SHALLOW WATER EQUATION
Get PDFAbstract. A two-dimensional shallow water equation integrated on depth water based on finite differential methods. Numerical solutions with different methods consist of explicit, implicit and semi-implicit schemes. Different methods of shallow water equations expressed in numerical schemes. For bottom-friction is described in semi-implicitly. This scheme will be more flexible for initial values and boundary conditions when compared to the explicit schemes. Keywords: 2D numerical models, shallow water equations, explicit and semi-implicit schema.ReferenceHassan, H. S., Ramadan, K. T., Hanna, S. N. 2010. Numerical Solution of the Rotating Shallow Water Flows with Topography Using the Fractional Steps Method, Scie.Res,App.Math. (1):104-117.Omer, S, Kursat, K. 2011. High-Order Accurate Spectral Difference Method For Shallow Water Equations. IJRRAS6. Vol. 6. No. 1.Kampf, J. 2009. Ocean Modelling for Beginners. Springer Heidelberg Dordrecht. London, New York.Wang, Z. L., Geng, Y. F. 2013. Two-Dimensional Shallow Water Equations with Porosity and Their Numerical scheme on Unstructured Grids. J. Water Science and Engineering. Vol. 6, No. 1, 91-105.Saiduzzaman, Sobuj. 2013. Comparison of Numerical Schemes for Shallow Water Equation. Global J. of Sci. Fron. Res. Math. and Dec. Sci. Vol. 13 (4).Sari, C. I., Surbakti, H., Fauziyah., Pola Sebaran Salinatas dengan Model Numerik Dua Dimensi di Muara Sungai Musi. Maspari J. Vol. 5 (2): 104-110.Bunya, B., Westerink, J. J. dan Shinobu, Y. 2004. Discontinuous Boundary Implementation for the Shallow Water Equations. Int. J. Numer. Meth. Fluids 2005 (47): 14511468
ANTIMICROBIAL ACTIVITY OF METHANOL EXTRACT FROM STEM BARK OF Cinnamomum sintoc
Get PDFAntimicrobial activity of methanol extract from stem bark of Cinnamomum sintoc has been evaluated against Candida albicans, Staphylococcus aureus and Escherichia coli. The extraction of compound was carried out by maceration, then isolation by column chromatograph, which yielded five (5) subfractions (A-E). Activity against fungus C. albicans, S. aureus bacteria dan E. coli using agar dilution method in paper disk. Methanol extract was not potent against antifungal activity but shows antibacterial activity with medium category. Subfraction C showed that antibacterial activity against S. aureus and E. coli with weak category, but subfractions D and E did not show any activity
TEACHING MEDIA DEVELOPMENT OF MATHEMATIC IN THE MATERIALS TRIGONOMETRY SUM AND TWO ANGLES DIFFERENCE BY USING GUI MATLAB
Get PDFAbstract. The aim of this research is to develop teaching media for mathematics specifically for materials on trigonometry using GUI Matlab. This media can be used as teaching and learning aid for students at senior high school, grade XI in the first semester. This learning media consists of instructions on how to use the media, learning materials, exercises and profile. The trigonometry materials which are discussed in this learning media consist of the sum and difference of two angles. The limitation on the angles that can be used are special angles in the interval -360o a,b 360o. The special angles are 0o, 30o, 45o, 60o, 90o, 120o, 135o, 150o, 180o, 210o, 225o, 240o, 270o, 300o, 315o, 330o, and 360o. The trigonometry functions such as sinus, cosine and as well as the operation addition (+) and subtraction (-) can be selected by hitting the appropriate button. Within each step, there is a check button and a next button to check the input true or false. If the value that entered incorrectly then the next step will not displayed and warning box will appear to report the location of error. Users have to fix the error in order to continue to the next step. Keywords: teaching learning media, trigonometry, GUI Matla
INHIBITION TEST OF METHANOL EXTRACT FROM SOURSOP LEAF (Annona muricata Linn.) AGAINST Streptococcus mutans BACTERIA*
Get PDFAbstract. Dental caries is a disease with a high prevalence of caries in Indonesia is caused by the bacterium Streptococcus mutans. The leaves of the soursop (Annona muricata Linn.) is one of the herbs that can remove dental plaque. This study aims to determine the chemical content and measure the inhibitory antibacterial soursop leaft methanol extractin inhibiting the growth of Streptococcus mutans bacteria. Phytochemical screening stated that the leaf of the soursop contains flavonoids, alkaloids, tannins, steroids, glycosides and saponins. Test of inhibition were measured using paper disc diffusion method with variation concentrations of 5, 10, 15 20, and 25%, positive control is tetrasilkin 30 g, and a negative control is methanol. Antibacterial test results showed that the methanol extract of soursop leaves have antibacterial activity against Streptococcus mutans at concentrations of 5, 10, 15, 20 and 25% with inhibitory diameter of 9,1; 10,57; 11,53; 12,01 and 13,75 mm respectively.Keywords: Soursop leaves, Dental caries, Streptococcus mutans, Methanol.*Judul ini telah dipresentasikan pada Seminar Nasional: Indonesian Students Conference on Science and Mathematics (ISCSM) 11-12 November 2015, Banda Aceh Indonesi
TREND ANALYSIS OF EXTREAM RAINFALL FROM 1982 - 2013 AND PROJECTION FROM 2014 - 2050 IN BANDA ACEH AND MEULABOH
Get PDFAbstract. Climate change is a global phenomenon that currently and seriously impacts the environment. Increasing concentrations of greenhouse gases have caused changes in extreme climate events. We have studied index rainfall extream trend at two meteorological stations of Sultan Iskandar Muda in Banda Aceh and Cut Nyak Dien in Meulaboh from 1982-2013. Daily rainfall data were processed using software of RClimDex to obtain the extreme rainfall index. Such indexes are extreme climate index set by the expert team for Climate Change Detection Monitoring and Indices (ETCCDMI) including of maximum 1-day and 5-days precipitation amount (RX1day and RX5day), total annual precipitation (PRCPTOT), consecutive dry days (CDD), consecutive wet days (CWD), very wet days (R95p), extremely wet days (R99p) and heavy precipitation days (R20mm). Based on our study, we found that the PRCPTOT tend to decrease, whereas occurances of RX1day and RX5day increase. The Banda Aceh station which has a monsoonal pattern is charaterized by increasing in R95p and R99p as well as but decreasing in R20mm. The CWD and CDD tend to accumulate at once. The Meulaboh station that has the type of equatorial rain show decreasing trend in R95p and R99p, but increasing trend in R20mm. The CWD and CDD occur within some days. The projection Representative Concentration Pathways (RCP) 4.5 and 8.5 from 2014-2050 showed an increasing pattern frequency of rain in Banda Aceh and a decreasing pattern in Meulaboh.Keywords: Trend, Extream Climate Index, ProjectionREFERENCELutgens. F.K. and Tarbuck. E.J. 2004. The Atmosphere: An Introduction to Meteorology. Pearson Prentice Hall. New Jersey.Ratag, M.A., Halimurrahman, Juaeni, I., Siswanto, B., dan N., Adikusumah. 2002. Perubahan Iklim : Basis Alamiah dan Dampaknya. Bandung, Lembaga Penerbangan dan Antariksa Nasional.IPCC, 2013. Climate Change. World Meteororogical Organization. Switzerland.Nuraini, Ida Sartika. 2014. Analisis dan Proyeksi Trend Temperatur dan Curah Hujan untuk Mendeteksi Perubahan Iklim (Studi Kasus Provinsi Kalimantan Barat). STMKG, Tangerang Selatan.Sulistya, W., Swarinoto, T.S., Zakir, A.,Riyanto, H., dan B., Ridwan.1998. The Impact of El Nino 1997/98 over Indonesia Region. Jakarta: Jurnal Meteorologi dan Geofisika, No 4, Desember.Zhang, X., and Feng Yang, 2004. RClimDex User Manual. Climate Research Branch, Environment Canada, Downsview, Ontario, Canada.Aldrian, E., 2007 Perubahan iklim global dan dampak terhadap iklim benua mantim di laut dan di daratan Prosiding Jumal Club Tahun 2007.Badan Meteorologi dan Geofisika. ISBN:978-979-1241-11-
DESIGNING APPLICATION OF ANT COLONY SYSTEM ALGORITHM FOR THE SHORTEST ROUTE OF BANDA ACEH CITY AND ACEH BESAR REGENCY TOURISM BY USING GRAPHICAL USER INTERFACE MATLAB
Get PDFBanda Aceh city and Aceh Besar Regency are two of the leading tourism areas located in the province of Aceh. For travelling, there are some important things to be considered, such as determining schedule and distance of tourism. Every tourist certainly chooses the shortest route to reach the destination since it can save time, energy, and money. The purpose of this reserach is to develop a method that can be used in calculating the shortest route and applied to the tourism of Banda Aceh city and Aceh Besar regency. In this reserach, Ant Colony Optimization algorithm is used to determine the shortest route to tourism of Banda Aceh city and Aceh Besar regency. From the analysis made by using both manual calculation and GUI MATLAB program application test, the shortest route can be obtained with a minimum distance of 120.85 km in one travel. Based on the test result, the application for tourism (in Banda Aceh city and Aceh Besar regency) shortest route searching built by utilizing the Ant Colony Optimization algorithm can find optimal route.Keyword:tourism, the shortest route, Ant Colony Optimizatio
ACTIVITY TEST OF Abrus precatorius L. LEAF EXTRACT AGAINST CLINICAL Streptococcus pneumonia GROWTH*
Get PDFAbstract. Saga (Abrus precatorius L.) have been used by Indonesian community as a traditional medicine. The research aims to determine the activity of the methanol extract of saga leaves to inhibit the growth of clinical Streptococcus pneumoniae growth. Inhibition tests was done with casting cup method. The results showed that the methanol extract of saga leaves at a concentration of 37,5; 50; 62,5; 75 and 87,5 mg/mL formed growth inhibition zone of clinical S. pneumoniae with consecutive average of 0,5; 1,75; 2,82; 4,00; and 4,82 mm. Based on the results of the research can be concluded that the methanol extract of saga leaves had activity in inhibiting the growth of clinical S. pneumoniae isolates with low category. Key words: Abrus precatorius L., Clinical Streptococcus pneumoniae, Methanol extract*Judul ini telah dipresentasikan pada Seminar Nasional: Indonesian Students Conference on Science and Mathematics(ISCSM) 11-12 November 2015, Banda Aceh Indonesi
ANTIOXIDANT ACTIVITY OF N-HEXANE EXTRACT OF NUTMEG PLANTS FROM SOUTH ACEH PROVINCE
Get PDFAbstract. It has tested the antioxidant activity of n-hexane extract respective roots, bark, fruit and seed crops of nutmeg against DPPH. Each extracted by maceration method with n-hexane. The extraction of each plant nutmeg with n-hexane extract obtained yield of n-hexane respectively 8,35%; 81,5%; 11,89% and 55,63%. The result of the antioxidant activity of n-hexane extract of each plant nutmeg against DPPH with a concentration of 25 ppm, 50 ppm and 100 ppm is obtained IC50, respectively, are 0,216 ppm, 63,755 ppm, 43,998 ppm and 11,599 ppm and positive control vitamin C ( IC50 = 3,657 ppm). Vitamin C is a standard compound is more often used than butyl for very high antioxidant activity. The antioxidant activity increases from high to low at the roots, seeds, fruits and bark of plants nutmeg in a row. Based on data GC-MS chemical components of each successive extracts of roots, bark, fruit and seeds are 41, 41, 44, 43 components of secondary metabolites. The main components of each part of the plant based on data from GC-MS are a 5-Octadecanoic acid, linalool, eugenol, myristicin, methoxyeugenol. The compounds are thought to play an active role in inhibiting free radicals from DPPH. n-Hexane extract nutmeg plant potential as an antioxidant.Keywords:Nutmeg (Myristica fragrans Houtt), n-hexane extract, Antioxidant, DPP