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Legal Framework for Data Processing in Employee Fluctuation Risk Analysis – the European Regulation from a German Perspective
No full textIn connection with the management of employee retention many Human Resources Managers feel the need to know who of their employees might leave the company in the near future. The more a company knows about the motives of those who might leave, the easier it is to get in contact with them.
Thus it is not surprising that the HR Managers want to try to combine all the data they have or can get in order to predict the behavior of their employees. It is evident that the interpretation of data-combinations can give inaccurate predictions of the probability of departure of an employee, and it is undesirable for this data-interpretation process to create a negative image of an employee. It is a sensitive issue for all parties involved, because managers want to retain the “good people” and keep the company going; on the other hand many employees are afraid of having all details of their work be observed. The uncertainties can hopefully be best dealt with by talking with each other. However, it is worth taking a look at the European legal situation in order to determine if these analyses are permitted at all.
Therefore it is necessary to examine whether and under what conditions an analysis of employee fluctuation risk is compatible with the GDPR, which has been applicable since May 25th, 2018, and which places special conditions on the processing of personal data in Europe
Towards Citizen Science Communication : How can citizen science enhance science communication?
No full textScience communication has shifted significantly in recent decades. From an early, widespread understanding that scientific findings were disseminated in a linear, closed pathway, there is now widespread acknowledgement of the need for more comprehensive and inclusive participation in science [cf. Massarani et al., 2017; Schäfer et al., 2015].
The project “Wir forschen”, which is part of the project “Innovation Hub 13 – fast track to transfer” coordinated by Technical University of Applied Science Wildau and Brandenburg University of Technology Cottbus-Senftenberg, explores methodological and practical characteristics of citizen science as a form of science communication. In this project, we outline an argumentation of understanding citizen science as science communication and furthermore introduce the term citizen science communication. In the processual course of the projects, different instruments of science communication come into play, which establish a dialog between the actors and initiate exchange with different intentions and approaches. In doing so, the project contributes to the science of science communication
LogisticsLab: An academic software for decision-making in logistics
No full textLogistical decision problems are a part of many courses in the field of logistics, management and operations research. It makes sense to illustrate these optimisation problems using case studies, which can be reproduced by students using suitable software. Often, solver add-ins in spreadsheets programs or general optimisation software are used, which on the one hand requires a high level of knowledge in Operations Research and on the other hand does not always allow an intuitive approach. This article describes the academic software LogisticsLab with which the distributors tie in with the idea of interactive decision support systems to systematically combine the experiences and intuitions of human decision-makers with the possibilities of computer-assisted modelling and optimisation of a wide range of logistical decisions
Influence of plasma treatment on SiO2/Si and Si3N4/Si substrates for large-scale transfer of graphene
No full textOne of the limiting factors of graphene integration into electronic, photonic, or sensing devices is the unavailability of large-scale graphene directly grown on the isolators. Therefore, it is necessary to transfer graphene from the donor growth wafers onto the isolating target wafers. In the present research, graphene was transferred from the chemical vapor deposited 200 mm Germanium/Silicon (Ge/Si) wafers onto isolating (SiO2/Si and Si3N4/Si) wafers by electrochemical delamination procedure, employing poly(methylmethacrylate) as an intermediate support layer. In order to influence the adhesion properties of graphene, the wettability properties of the target substrates were investigated in this study. To increase the adhesion of the graphene on the isolating surfaces, they were pre-treated with oxygen plasma prior the transfer process of graphene. The wetting contact angle measurements revealed the increase of the hydrophilicity after surface interaction with oxygen plasma, leading to improved adhesion of the graphene on 200 mm target wafers and possible proof-of-concept development of graphene-based devices in standard Si technologies
Antitumor efficiency of the natural alkaloid berberine complexed with C60 fullerene in Lewis lung carcinoma in vitro and in vivo
No full textBackground
Berberine (Ber) is a herbal alkaloid with pharmacological activity in general and a high anticancer potency in particular. However, due to its low bioavailability, the difficulty in reaching a target and choosing the right dose, there is a need to improve approaches of Ber use in anticancer therapy. In this study, Ber, noncovalently bound to a carbon nanostructure C60 fullerene (C60) at various molar ratios of the components, was explored against Lewis lung carcinoma (LLC).
Methods
C60–Ber noncovalent nanocomplexes were synthesized in 1:2, 1:1 and 2:1 molar ratios. Ber release from the nanocomplexes was studied after prolonged incubation at different pH with the liquid chromatography–mass spectrometry analysis of free Ber content. Biological effects of the free and C60-complaxated Ber were studied in vitro towards LLC cells with phase-contrast and fluorescence microscopy, flow cytometry, MTT reduction, caspase activity and wound closure assays. The treatment with C60–Ber nanocomplex was evaluated in vivo with the LLC-tumored C57Bl mice. The mice body weight, tumor size, tumor weight and tumor weight index were assessed for four groups, treated with saline, 15 mg C60/kg, 7.5 mg Ber/kg or 2:1 C60-Ber nanocomplex (15 mg C60/kg, 7.5 mg Ber/kg).
Results
Ber release from C60–Ber nanocomplexes was promoted with medium acidification. LLC cells treatment with C60–Ber nanocomplexes was followed by enhanced Ber intracellular uptake as compared to free Ber. The cytotoxicity of the studied agents followed the order: free Ber < 1:2 < 1:1 < 2:1 C60–Ber nanocomplex. The potency of cytotoxic effect of 2:1 C60–Ber nanocomplex was confirmed by 21.3-fold decrease of IC50 value (0.8 ± 0.3 µM) compared to IC50 for free Ber (17 ± 2 µM). C60–Ber nanocomplexes induced caspase 3/7 activation and suppressed the migration activity of LLC cells. The therapeutic potency of 2:1 C60–Ber nanocomplex was confirmed in a mouse model of LLC. The tumor growth in the group treated with 2:1 C60–Ber nanocomplex is suppressed by approximately 50% at the end of experiment, while in the tumor-bearing group treated with free Ber no therapeutic effect was detected.
Conclusions
This study indicates that complexation of natural alkaloid Ber with C60 may be a novel therapeutic strategy against lung carcinoma
Concept Towards Segmenting Arm Areas for Robot-Based Dermatological In Vivo Measurements
No full textDermatological in vivo measurements are used for various purposes, e.g. health care, development and testing of skin care products or claim support in marketing. Especially for the last two purposes, in vivo measurements are extensive due to the quantity and repeatability of the measurement series. Furthermore, they are performed manually and therefore represent a nonnegligible time and cost factor. A solution to this is the implementation of collaborative robotics for the measurement execution. Due to various body shapes and surface conditions, common static control procedures are not applicable. To solve this problem, spatial information obtained from a stereoscopic camera can be integrated into the robot control process. However, the designated measurement area has to be detected and the spatial information processed. Therefore the authors propose a concept towards segmenting arm areas through a CNN-based object detector and their further processing to perform robot-based in vivo measurements. The paper gives an overview of the utilization of RGB-D images in 2D object detectors and describes the selection of a suitable model for the application. Furthermore the creation, annotation and augmentation of a custom dataset is presented
Digitale Plattform für den Innovation Hub 13
No full textDas institutsübergreifende Transferprojekt Innovation Hub 13 soll eine Schnittstelle zwischen Wissenschaft, Wirtschaft und der Öffentlichkeit sein. Um dies zu realisieren, sollen digitale Werkzeuge und eine digitale Plattform den Transferscouts, die das Bindeglied zwischen den genannten Bereichen darstellen, eine Arbeitserleichterung verschaffen. Durch die Werkzeuge und die digitale Plattform sollen die Transferscouts kollaborativ mit Wissenschaft, Wirtschaft sowie Öffentlichkeit agieren und Kooperationen ermöglichen und in die Wege leiten. Eine systematische Verbreitung und Anwendung von wissenschaftlichem Know-how in die Projektregion ist dabei ein Ziel, was durch die digitale Plattform unterstützt werden kann. Zudem soll eine Öffnung der Hochschulen gegenüber der Zivilgesellschaft stattfinden sowie eine signifikante Verbesserung der Wissenschaftskommunikation erfolgen. Die Plattform soll dabei den gesamten Innovation Hub 13 digital abbilden. Das umfasst u.a. die Showrooms, die Testfelder und die Aktivitäten der Transferscouts. Dieses Working Paper zeigt auf, was eine digitale Plattform auszeichnet und welche Bestandteile diese beinhalten kann. Des Weiteren werden die konzeptionellen Arbeiten an der digitalen Plattform des Innovation Hub 13 dargelegt und einzelne Bausteine dieser digitalen Plattform beschrieben. Einige dieser Bausteine sind bereits umgesetzt und einzeln verwendbar. Zum Abschluss wird ein Ausblick über zukünftige Arbeiten an der konkreten digitalen Plattform des Innovation Hub 13 gegeben
Variant expression signatures of microRNAs and protein related to growth in a crossbreed between two strains of Nile tilapia (Oreochromis niloticus)
No full textNile tilapia (Oreochromis niloticus) is a species of worldwide importance for aquaculture. A crossbred lineage was developed through introgressive backcross breeding techniques and combines the high growth performance of the Chitralada (CHIT) lwith attractive reddish color of the Red Stirling (REDS) strains. Since the crossbreed has an unknown genetically improved background, the objective of this work was to characterize expression signatures that portray the advantageous phenotype of the crossbreeds. We characterized the microRNA transcriptome by high throughput sequencing (RNA-seq) and the proteome through mass spectrometry (ESI-Q-TOF-MS) and applied bioinformatics for the comparative analysis of such molecular data on the three strains. Crossbreed expressed a distinct set of miRNAs and proteins compared to the parents. They comprised several microRNAs regulate traits of economic interest. Proteomic profiles revealed differences between parental and crossbreed in expression of proteins associated with glycolisis. Distinctive miRNA and protein signatures contribute to the phenotype of crossbreed
Crack Propagation in As-Extruded and Heat-Treated Mg-Dy-Nd-Zn-Zr Alloy Explained by the Effect of LPSO Structures and Their Micro- and Nanohardness
No full textThe investigation of the crack propagation in as-extruded and heat-treated Mg-Dy-Nd-Zn-Zr alloy with a focus on the interaction of long-period stacking-ordered (LPSO) structures is the aim of this study. Solution heat treatment on a hot extruded Mg-Dy-Nd-Zn-Zr (RESOLOY®) was done to change the initial fine-grained microstructure, consisting of grain boundary blocky LPSO and lamellar LPSO structures within the matrix, into coarser grains of less lamellar and blocky LPSO phases. C-ring compression tests in Ringer solution were used to cause a fracture. Crack initiation and propagation is influenced by twin boundaries and LPSO lamellae. The blocky LPSO phases also clearly hinder crack growth, by increasing the energy to pass either through the phase or along its interface. The microstructural features were characterized by micro- and nanohardness as well as the amount and location of LPSO phases in dependence on the heat treatment condition. By applying nanoindentation, blocky LPSO phases show a higher hardness than the grains with or without lamellar LPSO phases and their hardness decreases with heat treatment time. On the other hand, the matrix increases in hardness by solid solution strengthening. The microstructure consisting of a good balance of grain size, matrix and blocky LPSO phases and twins shows the highest fracture energy
Contours of citizen science: a vignette study
No full textCitizen science has expanded rapidly over the past decades. Yet, defining citizen science and its boundaries remained a challenge, and this is reflected in the literature—for example in the proliferation of typologies and definitions. There is a need for identifying areas of agreement and disagreement within the citizen science practitioners community on what should be considered as citizen science activity. This paper describes the development and results of a survey that examined this issue, through the use of vignettes—short case descriptions that describe an activity, while asking the respondents to rate the activity on a scale from ‘not citizen science’ (0%) to ‘citizen science’ (100%). The survey included 50 vignettes, of which five were developed as clear cases of not-citizen science activities, five as widely accepted citizen science activities and the others addressing 10 factors and 61 sub-factors that can lead to controversy about an activity. The survey has attracted 333 respondents, who provided over 5100 ratings. The analysis demonstrates the plurality of understanding of what citizen science is and calls for an open understanding of what activities are included in the field