Jurnal Mahasiswa PSPD FK Universitas Tanjungpura
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UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP Staphylococcus aureus SECARA IN VITRO
Get PDFBackground: Areca nut potential as antibacterial need scientific studiesas consideration for maximal and directional exploration. Objective: The objective was to confirm the antibacterial activity, to knowthe chemical compounds and to determine Minimum InhibitoryConcentration (MIC) of ethanolic extract of Areca nut. Methods: Ethanolic extract of Areca nut was made from macerationprocess by using ethanol 96%. Antibacterial activity assays was performedusing Kirby-Bauer disc diffusion method against Staphylococcus aureus invitro. Ethanolic extract of Areca nut was diluted in 10 % DMSO to 0,5%;1%; 1,5%; 2%; 2,5%; 3% concentrations. Chloramphenicol and 10%DMSO were also used as control solutions. Result: The result showed that the phytochemical of Areca nut extractcontains phenols, flavonoids, tannin, saponins, triterpenoids, glycosidesand alkaloids. Antibacterial activity was reflected by the diameter of thezone of inhibition around the disc with the average zone of inhibitionobtained from concentrations 2%; 2,5%; 3% in a row was 7,37 mm; 8,56mm; 11,22 mm. Conclusion: Ethanolic extract of Areca nut has antibacterial activiyagainst Staphylococcus aureus in vitro with minimum inhibitoryconcentration (MIC) was 2%.Key words: antibacterial, Areca nut ethanolic extract, Staphylococcus aureus 1) Medical School, Faculty of Medicine, Universitas Tanjungpura,Pontianak, West Kalimantan 2) Study Program of Pharmacy, Faculty of Medicine, UniversitasTanjungpura, Pontianak, West Kalimantan 3) Departement of Physiology, Faculty of Medicine, UniversitasTanjungpura , Pontianak, West Kalimanta
GAMBARAN TINGKAT KEPOSITIFAN BASIL TAHAN ASAM, ANGKA KONVERSI, DAN HASIL PENGOBATAN PADA PASIEN TUBERKULOSIS PARU KATEGORI I DI UP4 PROVINSI KALIMANTAN BARAT PERIODE 2009-2012
Get PDFBackground: In Indonesia, there are 429.730 new cases of TB and62.246 death because of TB every year. In sputum examination, sputumgrading assessed based on the number of acid fast bacili. Sputum gradingused to assess the degree of infectious in pulmonary tuberculosis patients.Smear conversion rate is an indicator used to monitor and assesstreatment of pulmonary tuberculosis. High conversion rate will be followedby higher cure rate.Objective: To describe sputum smear grading, smear conversion rate,and treatment outcome of pulmonary tuberculosis patients treated withcategory 1 regimen.Methods: This research used descriptive study with cross sectionalapproach. Data were taken from the medical records of TB patients whotreated category 1 regimen in 2009-2012. Univariate data analysis wasused to describe the distribution of gender, age, type of anti TB drugs,history of DM, sputum grading, conversion rate, and treatment outcome.Results: Distribution of the most subjects in this study were the male(58,82%), age between 22-28 years old (21,85%), type of anti TB drugsused fixed doses combination (85,72%), did not have diabetes mellitus(88,24%), and +1 of acid fast bacili grades (55,46%). Sputum conversionrate was found more than the national target. The most of treatmentoutcomes was cured (88,23%), and then were transferred out (5,04%),defaulted (3,36%), failure (2,52%), dan died (0,84%).Conclusion: Patients with higher grades of sputum positivity at thebegining of the treatment and lower sputum conversion rate at the endintensive phase have lower cure rate.Keyword: Sputum grading, Conversion rate, Treatment outcome1) Medical School, Faculty of Medicine, University of Tanjungpura,Pontianak, West Kalimantan.2) Department of Pulmonology, dr. Soedarso Hospital, Pontianak, WestKalimantan.3) Department of Nutrition, Faculty of Medicine, University ofTanjungpura, Pontianak, West Kalimantan
HUBUNGAN LAMA MENYUSUI PADA MULTIPARA DENGAN KEJADIAN KANKER PAYUDARA DI RSUD DOKTER SOEDARSO PONTIANAK
Get PDFBackground: Breast cancer is the most common malignancy among women patient in RSUD Dokter Soedarso Pontianak. One of thereproductive factors that associated with decrease risk of breast cancer isbreastfeeding. Breastfeeding is reported lower in multiparous women.Objective: This research aimed to evaluate the association betweenduration of breastfeeding in multiparous women with breast cancerincidence at RSUD Dokter Soedarso Pontianak. Method: This researchwas hospital based case control study that has been conducted atoncology surgery clinic at RSUD Dokter Soedarso Pontianak from August2013 to August 2014, samples were 24 women with breast cancer and 24controls. Research instruments were medical record and questionnaire.Result: There is no significant association between breastfeeding durationin multiparous women and breast cancer incidence (p = 0.43).Breastfeeding characteristics that associated with decrease risk of breastcancer are age at first lactation 25-29 years (OR=0.50), number of childrenbreastfed ≥4 children (OR=0.47), age at last lactation ≥40 years(OR=0.25), average breastfeeding duration >12 months (OR=0.19), andlifetime breastfeeding duration >24 months (OR=0.46). Risk factors thatassociated with breast cancer incidence are family history of breastcancer, menopause, and use of ERT, cigarette, and alcohol (p<0.05).Conclusion: Breastfeeding duration in multiparous women is notassociated with breast cancer incidence at RSUD Dokter SoedarsoPontianak. Key words: Breast cancer, breastfeeding duration, multiparous women,risk factor 1) Medical School, Faculty of Medicine, University of Tanjungpura, Pontianak, West Borneo 2) Department of General Surgery, RSUD Dokter Soedarso, Pontianak, West Borneo 3) Department of Pediatric, Faculty of Medicine, University of Tanjungpura Pontianak, West Borne
KARAKTERISTIK PASIEN TB PARU YANG PATUH DAN TIDAK PATUH BEROBAT DI PUSKESMAS PERUMNAS II KECAMATAN PONTIANAK BARAT PERIOD 1 JANUARI - 31 DESEMBER 2010
Get PDFBackground: Pulmonary tuberculosis (TB) is a global infectious disease thatwas causing mortality in the world. Indonesia ranks fifth in the world that hasthe largest number of pulmonary TB cases. Pulmonary TB treatment needs along time to achieve healing and needs a combination of several kinds ofdrugs. The adherence is absolutely needed in pulmonary TB treatment toreach out the goal. It is important to know the characteristics of pulmonary TBpatients who adherent and non-adherent in pulmonary TB treatment.Methods: The study was a descriptive study with cross-sectional design.Object: To investigate the characteristics of pulmonary TB patients whoadherent to treatment and non-adherent to treatment in Perumnas II primaryhealth center, West Pontianak, on January 01 to December 31, 2010.Results: The patients who adherent to pulmonary TB treatment are 86.48%that have characteristics: in range of age 20-29 years, male, grade ofeducation in senior high school, have good knowledge about pulmonary TBdisease, and did not have drug side effects. The patients who non-adherentto pulmonary TB treatment are 13.51% that have characteristics: in range ofage 20-49 years, female, grade of education in elementary school, have poorknowledge about pulmonary TB disease, and have drug side effects.Key words: Characteristics, Adherence, Treatment, TuberculosisNotes:*Medical School, Faculty of Medical, Universitas Tanjungpura, Pontianak,West Kalimantan; **Departemen of Pulmonology, General Hospital of dr.Soedarso, Pontianak, West Kalimantan; ***Departemen of Biochemistry,Universitas Tanjungpura, Pontianak, West Kalimanta
PREVALENSI DAN FAKTOR-FAKTOR RISIKO YANG BERHUBUNGAN DENGAN TINGKAT GEJALA DEPRESI PADA MAHASISWA PROGRAM STUDI PENDIDIKAN DOKTER FAKULTAS KEDOKTERAN UNIVERSITAS TANJUNGPURA
Get PDFBackground: Depression is a mental disorder with the highest rates of mortality and morbidity in the world. Medical students have tendency to getdepression. Burdensome and stressful medical education contributes tothe development of depression symptoms among students. Objective:This study aimed to determine the prevalence and risk factors associatedwith depression symptoms level among medical students of TanjungpuraUniversity. Method: This study was analytic observational study with crosssectional approach, held at Tanjungpura University, Medical Faculty fromJanuary till June 2014. Data were collected using general questionnaireand Beck Depression Inventory II, also analyzed with Chi-Square andlogistic regression test. Results: Total samples were 208 students. Mostof subjects were female (57,2%), in the first year of study (35,1%), enteredthrough non-scholarship route (59,1%), living at home with parents(56,7%), had enough financial condition (68,8%), and used emotionfocusedcoping (60,1%). The prevalence of depression symptoms was30,8%, consisted of 15,4% mild depression, 13% moderate depression,and 2,4% severe depression. Depression symptoms were found highest infemale students (36,1%) and second year students (39,4%). Femalestudents had risk two times greater than male students while second yearstudent had risk three times greater than others students to getdepression. Conclusion: Female and second year medical students arethe greatest number of subjects who had depression symptoms. Keywords: Depression, medical students,and prevalence 1. Medical School, Faculty of Medicine, University of Tanjungpura,Pontianak, West Kalimantan. 2. Department of Pediatric, Faculty of Medicine, University ofTanjungpura, Pontianak, West Kalimantan
GAMBARAN KARAKTERISTIK AKSEPTOR KELUARGA BERENCANA DI PUSKESMAS ALIANYANG KOTA PONTIANAK TAHUN 2013
Get PDFLatar Belakang: Indonesia merupakan negara dengan jumlah pendudukterbanyak keempat di dunia (230 juta). Pemerintah sudah berupaya untukmengantisipasi laju pertumbuhan penduduk yang cepat ini dengan berbagaicara, salah satunya adalah dengan mencanangkan program KeluargaBerencana. Angka pengguna kontrasepsi di Indonesia sudah mencapai 62%.Data mengenai prevalensi pengguna kontrasepsi di Kalimantan Barat sudahada namun penelitian mengenai gambaran karakteristik akseptor keluargaberencana secara khusus di Kalimantan Barat belum pernah dilakukan.Tujuan: Mengetahui gambaran karakteristik akseptor keluarga berencana diPuskesmas Alianyang Kota Pontianak tahun 2013. Metodologi: Penelitiandeskriptif dengan menggunakan data primer dari hasil wawancara langsungterhadap responden yang merupakan akseptor KB suntik, pil dan IUD. Hasil: Jumlah respoden akseptor KB sebanyak 100 orang yang terdiri dari 45akseptor KB suntik, 29 akseptor KB pil dan 26 akseptor KB IUD. Kategoridengan proporsi terbesar pada ketiga metode kontrasepsi yang digunakanadalah kelompok usia 35-49 tahun (50%), jumlah anak yang telah dimilikiadalah 2 orang (49%), berasal dari suku Melayu (48%), beragama Islam((78%), pendidikan terakhir SMA/SLTA (46%), bekerja sebagai ibu rumahtangga (tidak bekerja) sebesar 52%, memperoleh informasi mengenai KBmelalui tenaga kesehatan (97%), memiliki IMT Pre-Obes 45%, dan tidakmemiliki riwayat penyakit 84%. Kesimpulan: Terdapat beberapa perbedaankarakteristik pada akseptor berdasarkan jenis metode kontrasepsi yangdigunakan.Kata Kunci: Karakteristik, Akseptor K
UJI EFEK EKSTRAK N-HEKSANA DAUN BAWANG KUCAI (Allium tuberosum Rottl ex Spreng) TERHADAP KOLESTEROL TOTAL PADA TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR WISTAR
Get PDFBackground: Garlic chives/kucai (Allium tuberosum Rotll ex Spreng)contain Allicin compound. The Allicin compound has an inhibitory effect forHMG-CoA reductase enzyme so that the cholesterol level was decreased.Objective: The research would investigate the effect of reduction totalcholesterol and effective dose of garlic chives’s n-hexane extract in malewistar rate compared with atorvastatin as possitive control. Method: Theresearch was a time series experiment. Twenty five wistar rat wasrandomly divided into 5 experimental group, negative control (CMC 1%),positive control (atorvastatin), dose I (0,0225 g/200 gBW), dose II (0,045g/200 gBW), and dose III (0,09 g/200 gBW) that was induced by highcholestrol diet for 14 days. The resulting data is analyzed with One-wayAnova test continued with LSD Post Hoc testing. Result: Fromphytochemical testing result, garlic chives n-hexane extract containsteroid/terpenoid secondary metabolite. Statistical analysis showedsignificance difference between average cholestrol level from controlgroup (negative and positif) againts dose I group and dose II group(p<0,05) at day-42. The effective dose was 0,09 g/200 gBB Conclusion:N-hexane extract of garlic chives has total cholestrol reduction effect onwhite male wistar rat with effective dose at 0,09 g/200 gBW which showthe same effectivity with atorvastatin.Key Words: Allium tuberosum Rottl ex Spreng, n-hexane extract of garlicchives, high cholestrol diet, total cholestrol level lowering effect 1) Medical School, Faculty of Medicine, Universitas TanjungpuraPontianak, Kalimantan Barat 2) Pharmacy School, Faculty of Medicine, Universitas TanjungpuraPontianak, Kalimantan Barat 3) Departement of Biochemistry, Medical School, Faculty of Medicine,Universitas Tanjungpura Pontianak, Kalimantan Bara
HUBUNGAN ANTARA FAKTOR PENGETAHUAN ISTRI DAN DUKUNGAN SUAMI TERHADAP KEJADIAN UNMET NEED KB PADA PASANGAN USIA SUBUR DI KELURAHAN SIANTAN TENGAH KECAMATAN PONTIANAK UTARA TAHUN 2014
Get PDFBackground: Unmet need for family planning is reproductive couple whowant to delay pregnancy or do not want to have more children, but do notusing any method of contraception. Among subdistricts in pontianak citythe highest prevalence of unmet need for family planning is found in NorthPontianak (18,97%). The highest number of reproductive couple is foundin Central Siantan (6326 couples). Wife’s knowledge and husband’ssupport are suggested to influence the incindence of unmet need forfamily planning. Objective: To determine the relationship between wife’sknowledge and husband’s support toward the incidence of unmet need forfamily planning. Method: This research was an analytic study with crosssectionalapproach conducted from April to June 2014. As much as 96reproductive couple were included in this study. Data was analyzed usingChi-Square test. Result: There were relationship between wife’sknowledge and husband’s support toward the incidence of unmet need forfamily planning with p=0,000 and p=0,000, rescpectively. Conclusion:wife’s knowledge and husband’s support are related to unmet need forfamily planning.Keywords: unmet need for family planning, wife’s knowledge, husband’ssupport. 1. Medical School, Faculty of Medicine, Universitas Tanjungpura,Pontianak, West Kalimantan. 2. Departement of Public Health, Faculty of Medicine, UniversitasTanjungpura Pontianak, West Kalimantan. 3. Departement of Physiology, Faculty of Medicine, UniversitasTanjungpura, Pontianak, West Kalimantan
GAMBARAN TINGKAT PENGETAHUAN DAN SIKAP REMAJA PUTRI TERHADAP KEPUTIHAN DI SMA NEGERI 2 PONTIANAK TAHUN 2013
Get PDFBackground. Leucorrhea is a reproductive health problem that almost75% of women at all ages experienced, both physiological andpathological. The study show that 75% women worldwide sufferleucorrhea at least once in their life. Female adolescent is a group thathad susceptible to leucorrhea problem. Objective. The purpose of theresearch was to know the distribution of knowledge and attitude aboutleucorrhea in SMAN 2 pontianak on 2013. Metodology. This study was adescriptive observational study with cross-sectional design. The samplefor this study are 59 sample. Date were obtained trought quetionnaires.Result. Of the 59 sample obtained, 44 sample (74,6%) have highknowledge, 46 sample (78%) have positive attitude. Conclusion. It wasconcluded that sample have good knowledge and positive attitude. Thebetter knowledge of a person to an object that it will better the personattitude toward the object. Keywords : Knowledge, Attitude, Leucorrhe
GAMBARAN PENGETAHUAN, SIKAP DAN MOTIVASI MENGENAI DONOR DARAH PADA DONOR DARAH SUKARELA DI UNIT DONOR DARAH KOTA PONTIANAK TAHUN 2013
Get PDFLatar Belakang: Ketersediaan darah di Unit Donor Darah diperoleh daridonor darah sukarela. Faktor faktor yang mempengaruhi donor darahsukarela seperti pengetahuan, sikap dan motivasi sangat penting untukmencapai ketersediaan darah yang cukup. Tujuan: Penelitian ini bertujuanuntuk menggambarkan tingkat pengetahuan, sikap dan motivasi mengenaidonor darah pada donor darah sukarela. Metode: Penelitian ini adalahpenelitian deskriptif dengan desain penelitian cross sectional. Pengambilansampel dilakukan menggunakan teknik consecutive sampling. Data diambildengan menggunakan kuesioner pada 70 respoden. Hasil: Distribusiproporsi responden yang paling banyak pada penelitian ini yaitu jeniskelamin laki-laki (84,82%), kelompok usia 17 30 tahun (54,28%), sarjana(35,73%), swasta (42,85%), penghasilan lebih dari Upah Minimum Kota perbulan (54,29%). Responden memiliki pengetahuan baik (65,71%), sikap baik(84,28%) dan motivasi baik (55,71%). Kesimpulan: Donor darah sukarelamemiliki pengetahuan, sikap dan motivasi yang baik.Kata Kunci: Pengetahuan, Sikap, Motivasi, Donor darah sukarel