Jurnal Mahasiswa PSPD FK Universitas Tanjungpura
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POLA DISTRIBUSI PASIEN KOLELITIASIS DI RSU DR. SOEDARSO PONTIANAK PERIODE JANUARI 2010 PERIODE JANUARI 2010-DESEMBER 2011
Background:Gallstone disease known as cholelithiasis is one of the mostcommon digestive surgical disorder in the United States and in developedcountry in general. Individual with symptomatic gallstones may experiencevarious gartrointestinal symptoms and are also at risk of developing acutecholecystitis and other complications although the majority of individualswith gallstones remain asymptomatic.Objective: This research was aimed to know the distribution ofcholelithiasis patients according to age, sex, main symptom, additionalsymptom, and complication in dr. Soedarso General Hospital Pontianakduring the period of January 2010-December 2011.Method: This research was a descriptive study with cross-sectionalapproach which was conducted by using secondary data from medicalrecords.Result: Among a total of 99 cholelithiasis patients, 63 (63,6%) werefemales and 36 (36,4%) were males with ratio (F:M) was 1,75:1. Most ofpatients were in age group of 41-48 years (23,2%) with femalepredominance (ratio F:M=1,6:1). The most common main symptom wasupper right quadrant pain (55,6%) and followed by epigastrium pain(44,4%). The most common additional symptom was nausea and/orvomitting (76,8%). There were 47 (47,5%) patients had complication; 36(36,4%) had cholecystitis, 9 (9,1%) had jaundice, and 2 (2,0%) had acutepancreatitis.Conclusion: The most common cholelithiasis patients were female and inage group of 41-48 years. The most common main symptom was upperright quadrant pain. The most common additional symptom was nauseaand/or vomitting. The most common complication was acute cholecystitis.Keyword: cholelithiasis, age, sex, main symptom, additional symptom,complication, dr. Soedarso General Hospital Pontiana
HYPOGLYCEMIC EFFECT TEST OF SWEET POTATO (Ipomoea batatas) LEAVES ETHANOL EXTRACT AGAINTS BLOOD GLUCOSE LEVEL OF ALLOXAN-INDUCED WHITE MALE WISTAR RAT (Rattus norvegicus)
Background: Hot water infusion of sweet potato (Ipomoea batatas) leaves empirically used as oral antidiabetic. Sweet potato leaves contain manypholyphenol compound which can reduce blood glucose level. Objective:This study investigated the hypoglycemic effect and effective dose ofsweet potato leaves ethanol extract compared to metformin in alloxaninducedmale Wistar rat. Method: The study was an in vivo experimental.Thirty male Wistar rats was randomly divided into 5 experimental groupsthose were negative control (CMC 0,5%), positive control (metformin), dose 1 (1,4 g/kgBW extract), dose 2 (2,8 g/kgBW extract), and dose 3 (5,6 g/kgBW extract). The rats were induced by alloxan and the treatment eachgroup was given for 7 days. The resulting data is analyzed with One-wayAnova test then continued with LSD Post Hoc test. Result: Based on thephytochemical screening, sweet potato leaves ethanol extract containflavonoid and tannin. Statistical analysis showed significant differencebetween average of fasting blood glucose level from control group(negative and positive) with dose 1 group (p<0,05) in post test fastingblood glucose measurement. Effective dose of sweet potato leaves extractwas 700 mg/200 gBW. Conclusion: Ethanol extract of sweet potatoleaves was suspected had blood glucose reduction effect in alloxaninducedmale Wistar rat with effective dose at 700 mg/200 gBW whichshowed better effect than metformin.Key words: Ipomoea batatas, sweet potato leaves ethanol extract, alloxaninduction, phytochemical screening, blood glucose reduction
UJI AKTIVITAS ANTIBAKTERI EKSTRAK KASAR BIJI BUAH LANGSAT (Lansium domesticum Corr.) terhadap Bakteri Staphylococcus aureus
Background: increasing number of Staphylococcus aureus resistant toantimicrobial medicine makes traditional medicine commonly used. Previousresearch which investigate langsat seed infuse effect to Salmonella typhishows negative result, so that research is continued by replacing the langsatseed infuse to crude extract. Objective: The aim of this study was toinvestigate secondary metabolite and antibacterial activity of ethanol 96%extract and n-Hexane extract of Lansium domesticum Corr. seed throughMinimum Inhibitory Concentration (MIC) and Minimum BactericidalConcentration (MBC) measurement. Method: this research was anexperimental study with complete randomized design and posttest onlycontrol group design. Phytochemical screening performed by test tubemethod. Antibacterial activity test determined by tube dilution method in100%; 50%; 25%; 12,5%; 6,25%; 3,125%; 1,56%; 0,78%; 0,39%; and 0,19%concentrations. Positive control contained bacterial suspension and agarmedium, negative control contained extract dilution and agar medium, andsolvent control contained tween 20 solution, bacterial suspension and agarmedium. Results: Secondary metabolite content of ethanol 96% extract ofLansium domesticum Corr. were alkaloids, flavonoids, saponins, tannins,phenols, and terpenoids. Secondary metabolite content of n-hexane extract ofLansium domesticum Corr. were saponins, and terpenoids. MIC of ethanol96% extract and n-hexane extract could not be measured because of turbiditywhich caused by tween 20 solution. MBC of ethanol 96% extract obtained in100% concentration, while MBC of n-hexane extract in 100% and 50%concentration. Conclusion: Crude extracts of Lansium domesticum Corr.seed has antibacterial activity against staphylococcus aureus.Keywords: Antibacterial, Crude extracts of Lansium domesticum Corr.,Staphylococcus aureus, 1) Medical School, Faculty of Medicine, University of Tanjungpura Pontianak,West Kalimantan. 2) Biology Departement, Mathematic and Science Faculty, University ofTanjungpura Pontianak, West Kalimantan. 3) Pharmacology Departement, Medical School, Faculty of Medicine,University of Tanjungpura Pontianak, West Kalimantan
GAMBARAN LUARAN HASIL PERSALINAN PADA PASIEN PREEKLAMSIA-EKLAMSIA DI RSUD DR SOEDARSO PERIODE 1 JANUARI 2011-31 DESEMBER 2011
Background. Preeclamsia is a pregnancy-specific syndrome whichreduce organ perfusion because of vasospasm and endothelial activation.The combination of proteinuria and hypertension during pregnancy willincrease the risk of perinatal and maternal mortality and morbidity. Objective. This research would characterized patient, neonatal outcomeand maternal outcome at dr. Soedarso General Hospital Pontianak. Method. This research is a descriptive study. The sample was taken bynon probability sampling with consecutive sampling. This research was carried out at dr. Soedarso General Hopital on December 2011-June2012. The data were taken from Medical Record at dr. Soedarso GeneralHospital Pontianak. Result. Total case of preeclamsia-eclamsia were 275 patient which 219maternal and 232 neonatal became the sample of this research. Characteristic of patients was mostly on 20-30 years old patiens (18,7%),nullipara (39,7%) and gestational age >37 weeks (78,1%). Neonataloutcome with severe asphyxia was 9,1% and moderate ashpyxia was16,3%. Morbidity on maternal was 23,7%, which are hypertensiveretinopathy (5,9%), solutio placenta (1,8%), pain in epigastric regio (1,4%),pulmonary edema (0,9%), HELLP syndrome (0,5%), postpartum eclamsia(0,5%), hemiparesis sinistra and NVII peripheral lesion (0,5%), dyspnea(0,5%), decompensation cordis (0,5%), hematoma placenta (0,5%) andascites (0,5%). Maternal mortality was 0,9% and neonatal mortality was9,9%. Conclusion. The characterize of maternal preeclamptic-eclamptic patientswas 20-30 years old, nullipara and gestational age >37 weeks.Preeclamsia-eclamsia cause morbidity and mortality on neonatal andmaternal. Keyword: Preeclamsia-eclamsia, neonatal outcome, maternal outcome1. Medical School, Faculty of Medicine, University of Tanjungpura Pontianak, West Kalimantan2. Department of Obstetrics and Gynecology, dr. Soedarso General Hospital Pontianak, West Kalimantan3. Departement of Parasitology, Medical School, Faculty of Medicine, University of Tanjungpura, Pontianak, West Kalimanta
Uji Aktivitas Antibakteri Ekstrak n-Heksana Biji Buah Langsat (Lansium domesticum Corr ) Terhadap Bakteri Escherichia coli secara In Vitro
Background: The role of medical plants today is more evident with theincrease of knowledge of the properties of various plants that are thecultural heritage of the nation. Langsat (Lansium domesticum Correa) isone of the local plants that have the potential to be developed, langsat hasmany uses and benefits, one of which is used to treat diarrhea. The mostcommon bacteria that cause diarrhea is Escherichia coli. The resistancerates of E. coli is still increasing overtime, so the need to find analternative antibacterial that sensitive to E. coli in necessary . Objectives:This study aims to determine the antibacterial activity of n-hexane extractof langsat seeds against Escherichia coli, to determine the content ofsecondary metabolites contained in the extract, to determine minimuminhibitory concentration (MIC), and minimum bactericidal concentration(MBC) of extract againts Escherichia coli. Methodology: Langsat seedsextracted using maceration method with solvent n-hexane. Testantibacterial activity against Escherichia coli bacteria using a tube dilutionmethod to determine the MIC and MBC. Result: Based on phytochemicalscreening, n-hexane extract containing saponin compounds and terpenoidcompounds. MIC extract n-hexane can not be determined, and n-hexaneextract of langsat seeds does not have MBC againts Escherichia coli.Conclusion: Extract n-hexane of langsat seed has no antibacterial activityagainst Escherichia coli.Keywords: antibacterial, Langsat seed, Escherichia coli. 1) Medical School, Faculty of Medicine, University of TanjungpuraPontianak, West Borneo. 2) Biology School, Faculty of Mathematic and Scientific, University ofTanjungpura Pontianak, West Borneo. 3) Medical School, Faculty of Medicine, University of TanjungpuraPontianak, West Borneo
HUBUNGAN ANTARA KEMAMPUAN PENDENGARAN DAN RADIUS RUMAH PADA WARGA MASYARAKAT DI SEKITAR PLTD SIANTAN HILIR
Background: Electric power is the most fundamental need in supports peoplelife. The impact which emerge in the proccess of operati ng electric generatorwith diesel power (PLTD) is the noise which came from the diesel machi ne.Objective: This research was aimed to know the correlation between theability to hear and the distance of people houses around PLTD indownstrream Siantan.Methodes: This research was an analytic study with cross-sectional approach.92 subjects were chosen as sample by using cluster random sampling technique. Subjects were examined by usi ng tuning fork examination (ri nne,weber, and schwabach test) and were categori zed into normal group and hindrance group. According to the distance of people houses from PLTD indownstream Siantan, subjects were categorized into <100 meters and?100 meters. The data were analyzed by using Statistical Product and ServiceSolution 17.00 programme.Results: There was correlation that statistically significant between the abilityto hear and the distance of people houses around PLTD in downstream Siantan (P<0,027). The relati ve risk (prevalens ratio [RP] and the reliableinterval 95% [IK]) of hearing impairments on respondents who are at a radius of less than 100 meters was (RP 1,86; IK 1,072,37).Conclusion: There was corelation that statistically significant between the ability to hear and the distance of people houses around PLTD (electricgenerator with diesel power) in downstream Siantan. The house distance is the risk factor of hi ndrancing the ability to hear. In this case, subjects whosestated less than 100 meters from the PLTD have 1,9 times higher risk thansubjects whose stated more than equal to 100 meters from PLTD (electric generator with diesel power) in downstream Siantan.Keywords: the ability to hear, the house distance, noise induced hearing los
GAMBARAN EPIDEMIOLOGI PENYAKIT KUSTA DI KECAMATAN SUI KAKAP KABUPATEN KUBU RAYA PROVINSI KALIMANTAN BARAT TAHUN 2012
Latar belakang: Penyakit kusta masih menjadi masalah kesehatanIndonesia karena selain menderita karena penyakitnya, penderita jugadikucilkan masyarakat. Menurut WHO, Indonesia menduduki peringkatke-3 di dunia sebagai penyumbang kasus terbanyak. Tujuan:Menggambarkan epidemiologi penyakit kusta di Kecamatan Sui KakapKabupaten Kubu Raya Provinsi Kalimantan Barat tahun 2012. Metodepenelitian: Penelitian ini merupakan penelitian deskriptif denganpendekatan cross-sectional. Hasil: Prevalensi kusta di Kecamatan SuiKakap sebesar 0,84 per 10.000 penduduk, dengan distribusi padaPuskesmas Sui Kakap, Punggur dan Sui Rengas yang ada dikecamatan ini, yaitu: 0,8, 1,7 dan 0,3 per 10.000 penduduk. Persentaseterbanyak tiap-tiap variabel dari 9 responden, yaitu: usia dewasa(100%), laki-laki (67%), Madura (44,5%) dan Bugis (44,5%), tipe MB(78%), BTA positif (78%), tidak ada riwayat narakontak (56%), sukarela(78%), tidak sekolah (33,5%) dan tamat SMP/sederajat (33,5%), petani(34%), jarak pelayanan kesehatan jauh (89%) dan PHBS buruk (89%).Kesimpulan: Prevalensi kusta di Kecamatan Sui Kakap sebesar 0,84per 10.000 penduduk, dengan distribusi pada Puskesmas Sui Kakap,Punggur dan Sui Rengas yang ada di kecamatan ini, yaitu: 0,8, 1,7 dan0,3 per 10.000 penduduk. Penderita kusta terbanyak berada pada usiadewasa, berjenis kelamin laki-laki, suku Madura dan Bugis, tipe kustaMB, hasil pemeriksaan BTA positif, tidak ada riwayat narakontak,berobat secara sukarela, tidak sekolah dan tamat SMP/sederajat,bekerja sebagai petani, jarak pelayanan kesehatan terhadap tempattinggal penderita jauh dan penerapan ber-PHBS yang buruk. Kata kunci: Kusta, Gambaran epidemiologi, Kecamatan Sui Kaka
Korelasi Derajat Osteoartritis Lutut Menurut Kellgren dan Lawrence dengan Tes Timed Up and Go (TUG) pada Pasien Osteoartritis Lutut di Klinik Bedah Ortopedi RSU dr. Soedarso Pontianak
Latar Belakang: Osteoartritis (OA) lutut adalah salah satu penyakitmuskuloskeletal yang paling sering di seluruh dunia. Penyakit inimerupakan penyebab utama gangguan dan kecacatan di usia lanjut.Seseorang dengan OA lutut dapat mengalami kehilangan keseimbangansecara progresif dan menurunnya kekuatan otot kuadrisep. Tujuan:Tujuan dari penelitian ini adalah mencari korelasi derajat radiografiKellgren dan Lawrence (K/L) dengan tes Timed Up and Go (TUG) padapasien osteoartritis lutut. Metodologi: Sebanyak 63 pasien dengan OAlutut yang datang ke Klinik Bedah Ortopedi dilibatkan dalam penelitian ini.Diagnosis OA lutut berdasarkan pada kriteria dari American College ofRheumatology (ACR). Setelah dilakukan pemeriksaan fisik, derajatberatnya radiografi dievaluasi dengan derajat K/L. Tes TUG digunakanuntuk mengevaluasi fungsi aktivitas fisik pasien OA lutut. Hasil: Empatpuluh tiga pasien (68,3%) adalah perempuan. Rata-rata usia adalah 60,02(2SD 6,66) tahun dan rata-rata indeks massa tubuh (IMT) adalah 27,13(2SD 4,39) kg/m2. Rata-rata tes TUG adalah 12,90 (2SD 4,14) detik.Terdapat korelasi positif yang signifikan secara statistik antara derajat K/Ldengan tes TUG (r=0,537; p<0,001). Terdapat korelasi negatif yangsignifikan secara statistik antara IMT dengan tes TUG (r= -0,264;p<0,05). Kesimpulan: Tes TUG dapat digunakan sebagai indikatorderajat radiografi OA lutut, semakin singkat waktu dalam menyelesaikantes TUG, semakin baik derajat radiografinya.Kata kunci: Osteoartritis lutut, Kellgren dan Lawrence, Tes TU
Description of Body Mass Index in Tuberculosis Patient with Anti Tuberculosis Drugs Therapy in Unit Pengobatan Penyakit Paru Paru (UP4) Pontianak
Background. Tuberculosis is an infectious disease with a chronicinflammation caused by Mycobacterium tuberculosis. This disease affectsnutritional status to its patient through its chronic inflammation, causingsome serious malnutrition in most of the patients. Tuberculosis needs aspecial treatment with special drugs called Anti Tuberculosis Drugs in along period. These drugs can also worsen the nutritional status oftuberculosis patient through its side effects. Objective. This research wasmade to measure Body Mass Index (BMI) of TB patients at the beginningof therapy, after 2 months, and after 6 months of TB therapy. Method.Case records of active TB with first line therapy of ATD treated betweenDecember 2009 until December 2013 at UP4 Pontianak. Data was takenseparately between body weight, which is taken from case record, andbody height , which is taken from the patient due to the missing record inUP4, to measure the BMI after diagnosed, after 2 months, and after 6months of TB therapy. Result. Most of subject of this research areunderweight (66,7%) at the beginning of therapy, but after 6 monthstherapy most of subject of this research have normal BMI. Conclusion.There are some increasing of BMI from the beginning of the TB therapyuntil 6 months of TB therapy.Keywords: Tuberculosis, Body Mass Index, success of therapy.1. Program Studi Pendidikan Dokter, Fakultas Kedokteran UniversitasTanjungpura, Pontianak, Kalimantan Barat. 2. Pulmonology department of dr. soedarso General Hospital,Pontianak, Kalimantan Barat. 3. Nutrition department, Program Studi Pendidikan Dokter, FakultasKedokteran, Universitas Tanjngpura, Pontianak, Kalimantan Barat
GAMBARAN TINGKAT DEPRESI PASIEN DIABETES MELITUS TIPE 2 DI PUSKESMAS PURNAMA PONTIANAK TAHUN 2013
Background. Diabetes mellitus (DM)is a group of metabollic diseasethat classified in cronic disease with characteristic hyperglicemiathat happen because of insulin secretion defect, work of insulin, orboth. The impact of illness and treatment procedures are the stressorthat can cause depression. Objective. The objective of this researchwas to describe the level of depression in patients with DM type 2 inPuskesmas Purnama Pontianak. Method. The method used for theresearch was descriptive survey study. The subjects of this studywere 40 patients with DM type 2 in Puskesmas Purnama Pontianak.Sample taken by consecutive sampling. The qualified sample wasinterviewed with Beck Depression Inventory II (BDI II) for determiningthe level of depression. Result. The result shows that the prevalenceof depression in patients with DM type 2 is 25 %. In details, milddepression is 20 % and moderate depression 5 %. Conclusion.Majority of the depression level in patients with DM type 2 inpuskesmas Purnama Pontianak is mild depression and the dominantcharacteristics in respondent with depression are: age >60, female,married, senior high school graduated, and housewives.Keywords: Diabetes mellitus type 2 (DM type 2), Depression, BeckDepression Inventory II (BDI II)1)Medical School, Faculty of Medicine, Universitas Tanjungpura,Pontianak, West Kalimantan2)Department of Psychiatry, Faculty of Medicine, Universitas Tanjungpura,Pontianak, West Kalimantan3)Department of Health Community, Faculty of Medicine, UniversitasTanjungpura, Pontianak, West Kalimanta