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Learning Behaviors of Emergency Life-Saving Technicians' (ELSTs) and Supervisors' Coaching Behaviors 一 A Comparison Across Organizations of Different Jurisdiction Sizes 一
Full text link【概要】本研究の目的は, 救急救命士の経験学習行動, 越境的能力開発および上司のコーチング行動において, 管轄人口規模別の所属組織によってどのような違いがあるのかについて考察することである。540名の定量的調査の結果, 経験学習行動においては管轄人口規模が「30万人以上」の組織の救急救命士の平均値が総じて高く, 特に具体的経験や内省的観察において有意な差が示された。また, 上司のコーチング行動についても, 一つの項目を除いて管轄人口規模が「30万人以上」で平均値が高かった。今後, 管轄人口規模別の所属組織による救急救命士の学習行動やコーチング行動に影響する組織文化あるいは組織的取り組みに関してより詳細に検討する必要がある。The purpose of this study is to examine how emergency life-saving technicians’ (ELSTs) experiential learning behaviors, cross-organizational skill development, and supervisor coaching behaviors differ across organizations depending on jurisdictional population size. Results from 540 quantitative surveys showed that ELSTs from organizations with a jurisdictional population size of “300,000 or more” had generally higher averages in experiential learning behaviors, with significant differences especially in concrete experience and reflective observation. The mean values for supervisors' coaching behaviors were also higher in the jurisdictional population size of “300,000 or more,” with the exception of one item. Further research is needed to examine in more detail the organizational culture and efforts that influence ELSTs’ learning behaviors and coaching behaviors based on the size of the population.departmental bulletin pape
Introduction of the Research Project of High Pressure Protein Research Center for Allosteric Drug Discovery using a Cancer Metabolism-Related Factor, ENTPD5.
Full text link近畿大学の先端技術総合研究所高圧力蛋白質研究センターでは数年来、研究センターの基盤手法である計算科学・分子動力学シミュレーションとNMR分光学測定を柱として創薬研究に貢献する融合研究プロジェクトを構築・推進中である. 我々の融合研究は創薬研究でも初期段階の薬物候補化合物の開発に注力している. 具体的には、我々は創薬研究ターゲットの一つとしてがんに関係するENTPD5に注目したアロステリック薬剤に関する研究を遂行中である. 本研究ノートでは高圧力蛋白質研究センターのアロステリック薬剤創薬融合研究の背景や現状を解説すると共にその研究意義を明確に示し、計算科学利用の概要と最近開始された分子動力学シミュレーション研究の準備状況について報告する.Recently, High Pressure Protein Research Center, Institute of Advanced Technology, Kindai University has established and promoted a research project that contributes to drug discovery research based on computational science, molecular dynamics simulation and NMR spectroscopy measurements, which are the basic methods of our research center. The research focuses on the development of drug candidates in the early stages of drug discovery. We are conducting research on allosteric drugs, especially focusing on the cancer-related ENTPD5 protein as a drug discovery research target. In this note, we would like to describe the background and current status of the allosteric drug discovery research proposal at High Pressure Protein Research Center, clarify the significance of the research, and provide an overview of the use of computational science and the initial preparation status of the molecular dynamics simulation studies.departmental bulletin pape
Generation of bitterness by oral seasoning of rice cake with commercial beverages
Full text linkSome commercial beverages turn the sweet taste of rice cakes into bitter taste when we put them in the mouth. Here we investigated the mechanisms of bitterness generation by sensory evaluations. Eight healthy university students were recruited as subjects. After chewing about 13 g of rice cakes, a commercial sweet beverage (beverage A) was put together in the mouth. Bitterness scores for baked and boiled rice cakes were defined as 2 and 4, respectively. As a result, many commercial beverages (pH 3.5), but not water and barley tea (neutral pH), produced bitter taste similar to that of beverage A. Adjusting the pH of beverage A to 5.0 and 7.0 reduced bitterness significantly. Similar results were obtained with 0.2% lactic acid, tartaric acid, citric acid, and phosphoric acid (pH 3.5, 5.0, 7.0). Instead of rice cake, the rice produced reduced bitterness with the combination of beverage A. These results suggested that chemicals that elicit bitter taste under acidic conditions, but not neutral ones, may be released into the oral cavity (saliva) by chewing rice cakes.departmental bulletin pape
