Hochschulschriftenserver der Hochschule der Medien Stuttgart
Not a member yet
128342 research outputs found
Sort by
Review shows that parental reassurance and nutritional advice help to optimise the management of functional gastrointestinal disorders in infants
No full textRegurgitation, infantile colic and functional constipation are common functional gastrointestinal disorders (FGIDs) during infancy. Our aim was to provide carry out a concise review of the literature, evaluate the impact of these common FGIDs on infants and their families and provide an overview of national and international guidelines and peer-reviewed expert recommendations on their management
Optimization of fuel consumption and battery life cycle in a fleet of Connected Hybrid Electric Vehicles via Distributed Nonlinear Model Predictive Control
No full textThis paper proposes a distributed Nonlinear Model Predictive Control (NMPC) strategy for a fleet of connected Hybrid Electric Vehicles that move in a coordinated fashion, optimizing fuel economy and battery state of charge. The numerical validation is provided by considering a commuter cycle usually exploited during real on-the-road emission tests. Results, carried out by exploiting ADVISOR- a state of the art simulation environment for modeling and control of hybrid electric vehicles- confirm the effectiveness of the approach
Rafforzamento dei diritti processuali nel mutuo riconoscimento delle decisioni in absentia (d. lg. n. 31/2016)
No full textThe influence of rib stiffeners on the response of extended end-plate joints
No full textThe presence of rib stiffeners in extended end-plate joints influences the yield line distribution in the tensile zone
of the connection, the depth of internal lever arm as well as the resistance of compression components of the
joint. In addition, the stiffeners may affect the plastic rotation capacity of the connected beamin bothmonotonic
and cyclic regime. The current EN1993:1–8 (2005) gives limited recommendations on these issues, while
EN1998-1 (2005) does not provide any detailing rules to enforce ductile cyclic response when rib stiffeners are
adopted in end-plate connections. In order to investigate these criticisms, extensive parametric finite element
simulations were carried out and the obtained results are described and discussed in this paper. The main analyzed
parameters are the thickness, the slope (i.e. the depth to width ratio), and the constructional imperfections
of the rib stiffeners for different beam-to-column assemblies alternatively designedwith full and partial strength
connection. The monitored response from monotonic and cyclic analyses allows characterizing the yield line
distribution and the variation of internal forces into the rib and the bolt rows. The evolution of the internal
lever arm of the connection, the out-of-plane bending and torsional moments developing when the connected
beam experiences large plastic rotations as well as the forces acting on lateral torsional restraints are also
investigated
A model for dislocations in epitaxially strained elastic films
No full textA variational model for epitaxially strained films accounting for the presence of dislocations is considered. Existence, regularity and some qualitative properties of solutions are addressed
Flinovia - Flow Induced Noise and Vibration Issues and Aspects - II
No full textThis is the proceedings of the Second International Workshop on Flow Induced Noise and Vibration (FLINOVIA), which was held in Penn State, USA, in April 2016. The authors’ backgrounds represent a mix of academia, government, and industry, and several papers include applications to important problems for underwater vehicles, aerospace structures and commercial transportation. The book offers a valuable reference guide for all those working in the area of flow-induced vibration and noise.
Flow induced vibration and noise (FIVN) remains a critical research topic. Even after over 50 years of intensive research, accurate and cost-effective FIVN simulation and measurement techniques remain elusive. This book gathers the latest research from some of the most prominent experts in the field.
The book describes methods for characterizing wall pressure fluctuations, including subsonic and supersonic turbulent boundary layer flows over smooth and rough surfaces using computational methods like Large Eddy Simulation; for inferring wall pressure fluctuations using inverse techniques based on panel vibrations or holographic pressure sensor arrays; for calculating the resulting structural vibrations and radiated sound using traditional finite element methods, as well as advanced methods like Energy Finite Elements; for using scaling approaches to universally collapse flow-excited vibration and noise spectra; and for computing time histories of structural response, including alternating stresses
TRA TRADIZIONE E INNOVAZIONE. LA SFIDA DELL’INDUSTRIA CANTIERISTICA DELLA REGIONE POMERANIA
No full textLa storia recente della Pomerania, regione baltica della Polonia, è strettamente intrecciata all’evoluzione della cantieristica navale la cui genesi è rinvenibile negli anni Cinquanta del XIX secolo, quando l’intera regione era sotto il dominio della Prussia. Il governo teutonico aveva pre- disposto piani precisi per lo sviluppo dell’area che avrebbe dovuto fornire, alla costituenda flotta prus- siana, le nuove e veloci navi in acciaio. A questo scopo, a Danzica, sorsero i primi cantieri navali dove, tra la fine del XIX e l’inizio del XX secolo, oltre alla costruzione di scafi, motori navali, incrociatori e sottomarini, venivano effettuati lavori di manutenzione, ristrutturazione e riparazione (Pavino, 2014).
L’industria delle costruzioni e delle riparazioni navali, a parte la parentesi del periodo bellico, ha rappresentato uno dei traini di sviluppo della regione fino all’inizio degli anni Ottanta del XX secolo quando la Polonia era ormai diventata un significativo produttore mondiale di navi d’altura. I contrac- colpi del passaggio da un’economia pianificata, con forte centralizzazione, ad un regime di libero mer- cato dominato dai colossi asiatici, ha profondamente penalizzato il comparto cantieristico che, nel breve giro di qualche anno, nonostante gli aiuti e gli incentivi statali, ha vissuto una drastica riduzione delle commesse e dei posti di lavoro (Wrobel et al., 2016).
Da questa crisi ne è derivata l’esigenza di riformure le strategie diversificando le produzioni e con- centrandosi sulla qualità e sulla tecnologia che le navi prodotte avrebbero contenuto. Si iniziò così a pun- tare sulla costruzione di unità navali tecnologicamente sempre più avanzate: navi da crociera, traghetti alimentati da gas naturale liquefatto, navi per costruire campi offshore di generatori a pale eoliche, navi militari, inclusi i sottomarini (UNCTAD, 2005).
La regione Pomerania rappresenta oggi un importante hub logistico e commerciale il cui progresso è principalmente ascrivibile all’industria marittima, ai servizi portuali e alle grandi raffinerie che trattano e distribuiscono i prodotti derivati dal petrolio. Il contributo che si presenta, descrive la correlazione tra il cambio di passo nella struttura produttiva dell’industria navale della Pomerania e l’accelerazione delle perfomance economiche e commerciali regionali
Regulation of trafficking and folding of cellular prion protein PrPC and its shadow Shadoo
No full textCellular prion protein (PrPC) is a glycosyl-phosphatidyl-inositol (GPI) anchored glycoprotein whose precise function in the brain remains elusive but may depend upon its cellular localization. PrPC is able to misfold to a pathogenic isoform PrPSc, the causative agent of neurodegenerative prion diseases. The PrPSc formation and cellular propagation has been related to the presence of the PrP receptor 37/67 kDa LR (Laminin Receptor), as well as to a member of the prion protein family called Shadoo. The misfolded PrPSc is amyloidogenic and strictly related to expression, intracellular localization and association of PrPC itself to cholesterol enriched membrane microdomains (lipid rafts).
In this report we show our recent findings related to:
1.
The biological effects deriving from the treatment with specific 37/67 kDa LR inhibitor, NSC47924, on the trafficking and interaction between PrPC and its receptor
2.
The natural tendency of Shadoo to acquire in neuronal cells “prion-like” characteristics, such as misfolding and aggregation state, and the existence of its non-translocated ER form, whose presence into mitochondria is controlled by the chaperone TRAP1.
Altogether our findings contribute i) to reveal NSC47924 inhibitor as a useful tool to regulate PrPC and 37/67 kDa LR trafficking and degradation, representing a novel small molecule to be tested against prion diseases and ii) to understand the role of molecular chaperones and of PrP-related folding intermediates in “prion-like” conversion
The reuse of cultural heritage as an opportunity for urban regeneration
No full textCultural heritage represents a strategic resource for the social and the economic development of territories. Today, the pressures facing urban areas require new approaches and tools for managing change, combining the objectives of cultural heritage conservation with those of socio-economic development. This paper deals with the theme of the reuse of contemporary relevant architecture, in which the choice of the new use and the design solutions are guided by the objective of generating opportunities for regeneration and enhancement of the historic urban landscape. The case study is an eclectic style building, called ''Il Capricho'', on the island of Ischia (Naples), built at the end of 50s and abandoned at the beginning of this century. Multidisciplinary research develops a methodological path that, starting from the construction of a shared urban regeneration scenario, develops a project of re-use of the building, aimed - on one hand - to enhance its performance and its identity - on the other - to interpret the need to improve the environmental, social and economic conditions of the urban context