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Introduzione al ciclo di incontri "Fare ricerca per la tesi di laurea".
L'intervento introduce il ciclo di incontri dal titolo "Fare ricerca per la tesi di laurea. Banche dati e risorse digitali" evidenziando l'importanza e le criticità del lavoro di ricerca finalizzato all'elaborazione della tesi di laurea, sullo sfondo della rinnovata offerta formativa del Dipartimento di Giurisprudenza. Si svolgono poi alcune considerazioni di più spiccato interesse per lo studente che voglia approfondire le materie privatistiche, legate al pluralismo delle fonti e della complessità del sistema ed alla possibilità di riconoscere al diritto commerciale una sua autonomia e una sua logica interna rispetto al diritto civil
Nanomaterials for Skin Delivery of Cosmeceuticals and Pharmaceuticals
Skin aging is described as dermatologic changes either naturally occurring over
the course of years or as the result of the exposure to environmental factors (e.g., chemical products,
pollution, infrared and ultraviolet radiations). The production of collagen and elastin, the main
structural proteins responsible for skin strength and elasticity, is reduced during aging, while their
role in skin rejuvenation can trigger a wrinkle reversing effect. Elasticity loss, wrinkles, dry skin,
and thinning are some of the signs that can be associated with skin aging. To overcome skin aging,
many strategies using natural and synthetic ingredients are being developed aiming to reduce the
signs of aging and/or to treat age-related skin problems (e.g., spots, hyper- or hypopigmentation).
Among the different approaches in tissue regeneration, the use of nanomaterials loaded with
cosmeceuticals (e.g., phytochemicals, vitamins, hyaluronic acid, and growth factors) has become an
interesting alternative. Based on their bioactivities and using different nanoformulations as efficient
delivery systems, several cosmeceutical and pharmaceutical products are now available on the
market aiming to mitigate the signs of aged skin. This manuscript discusses the state of the art of
nanomaterials commonly used for topical administration of active ingredients formulated in
nanopharmaceuticals and nanocosmeceuticals for skin anti-aging
Mediterranean diet and Psoriatic Arthritis activity: a multicenter cross-sectional study
Diet is a modifiable factor implicated in chronic systemic inflammation, and the mediterranean dietary pattern is considered to be a healthy model in terms of morbidity and mortality. The main aim of this study was to evaluate the adherence to the mediterranean diet in patients with Psoriatic Arthritis (PsA) and its impact on disease activity. A cross-sectional observational study was conducted in a cohort of 211 consecutive PsA patients. We evaluated PsA activity by disease activity index for PSoriatic Arthritis (DAPSA) and composite psoriatic disease activity index (CPDAI). The NCEP-ACT III criteria were used to identify subjects with MetS, and in each subject, we evaluated body mass index (BMI). A validated 14-item questionnaire for the assessment of adherence to the mediterranean diet (PREDIMED) was recorded for all the enrolled subjects. Patients showed a median age of 55 (48-62) and disease duration was 76 (36-120) months. 27.01% of patients were classified as having MetS. The median of the mediterranean diet score (MDS) was 7 (6-9). A moderate adherence to mediterranean diet was found in 66.35% of the entire cohort; 15.64% and 18.01% of the patients showed low- and high adherence to the dietary pattern, respectively. We found a negative association between DAPSA and adherence to mediterranean diet (B = - 3.291; 95% CI - 5.884 to - 0.698). DAPSA was positively associated with BMI (B = 0.332; 95% CI 0.047-0.618) and HAQ ( B = 2.176; 95% CI 0.984-3.368). Results from our study evidenced that in PsA patients, higher levels of disease activity as measured by DAPSA correlated with low adherence to mediterranean diet, suggesting potential benefit of antinflammatory properties of this dietary pattern
Reason and Critique. Keys to Understanding Modernity
Some 20th-century philosophers emphasized “critique” as a key to understanding the practical and theoretical issues of the modern world. They also tried to establish the conditions for a transformative critique of what exists. In his famous essays of the 1930s, for example, Horkheimer presents critical theory as a multidisciplinary project and analysis that uncovers the internal and external contradictions caused by the market economy on which the modern world is based, with a view to sketching out a new society composed of free individuals. Critical theory thus challenges the established order and aims to fight against it: it pits against the “traditional theory”, which dates back to the origins of modern thought, a new model of scientificity going beyond dualisms and, in particular, the separation between subject and object. While differing from one another, these conceptions and practices of critique, which at times are clearly under the sign of Marx, show, firstly, that from the 15th century onwards, a system of discipline was being prepared with the aim of increasing human production and, secondly, that it is impossible to understand the development of modern thought and culture without analysing its relationship with that of its material basis, namely the mechanisms of power and the relations of production that characterise capitalist societies. How can modern thought, then, be reread on the basis of an analysis of the effects of power in relation to a rationality that has been historically and geographically defined in the West since the 15th century? To what extent can the concept and practice of “critique” be seen as a key to understanding modernity? Can we detect, as André Tosel suggests, in the long discourse of modernity – from Descartes, maybe even Luther –, a persistent self-critique and a self-destructive movement in which each critical gesture replaces previous ones by proposing a reading key that better corresponds to the changing problems of history and society? Should these approaches be carefully distinguished according to the principle on which they are based? Do certain (more or less) radical critical postures of the 20th century unquestionably create a profound break with the guidelines of modern thought (which, in the light of historical reconstructions by authors such as Cousin, Hegel, Feuerbach, go back to Bacon and Descartes) so that a clear boundary can be drawn between one and the other (for example, between traditional theory and critical theory, as Horkheimer argues)? Or are they in continuity with the critical approaches of modern philosophies? How does critical theory fit into the long discourse of modernity? From these problems it is necessary to identify the theoretical nodes of the “critical” interpretation of the modern era, an interpretation that highlights the ambiguity of the notion of progress, the intertwining of reason with power and the progressive decline of theoretical consciousness
Hay or silage? How the forage preservation method changes the volatile compounds and sensory properties of Caciocavallo cheese
The aim of this study was to determine the effect of the forage preservation method (silage vs. hay) on volatile compounds and sensory properties of a traditional Caciocavallo cheese during ripening. A brown-midrib sudangrass hybrid was cultivated on a 7-ha field and at harvesting it was half ensiled in plastic silo bags and half dried to hay. Forty-four lactating cows were equally allotted into 2 groups fed a isonitrogenous and isoenergetic total mixed ration containing as the sole forage either sorghum hay (H group) or sorghum silage (S group). Milk from the 2 groups was used to produce 3 batches/diet of Caciocavallo ripened for 30, 60, and 90 d. Milk yield and composition as well as cheese chemical and fatty acid composition were not markedly affected by the diet treatment and ripening time. By contrast, ripening induced increased levels of the appearance attribute “yellowness,” along with the “overall flavor,” the odor/flavor attributes “butter” and “hay,” the “salty,” “bitter,” and “umami” tastes, and the texture attribute “oiliness,” whereas the appearance attribute “uniformity” and the texture attribute “elasticity” were reduced. The silage-based diet induced higher perceived intensities of several attributes such as “yellowness”; “overall flavor”; “butter”; “grass” and “hay” odor/flavors; “salty,” “bitter,” and “umami” tastes; and “tenderness” and “oiliness” textures. In S cheese we also observed higher amounts of ketones and fatty acids. Conversely, H cheese showed the terpene α-pinene, which was not detected in S cheese, and a higher intensity of the appearance attribute “uniformity.” These differences allowed the trained panel to discriminate the products, determined an increased consumer liking for 90-d ripened cheese, and tended to increase consumer liking for hay cheese
Forschungsbericht 2019
Der vorliegende Forschungsbericht fasst die Leistungen der
Hochschule der Medien zusammen. Die „harten“ Drittmittel,
welche von der AGIV anerkannt werden, liegen weiterhin deutlich
über 3 Millionen Euro. Neben den klassischen Drittmitteln ist
die Hochschule der Medien zudem erfolgreich bei der Einwerbung
weiterer Förderungen. Diese wettbewerblich eingeworbenen
sonstigen Drittmittel haben ebenfalls erhebliche Forschungsanteile.
Ein Beispiel ist das Programm des Ministeriums für
Wissenschaft und Kunst zur Verbesserung der Lehre. Ebenfalls
erfolgreich war die Hochschule der Medien bei der Einwerbung
von Mitteln im Bereich der Startup-Förderung. So kommen wir
in der Summe auf ein gesamtes Drittmittelaufkommen von über
3,8 Millionen €.
Neben den reinen Zahlen – in 2019 wurde das zweithöchste
Drittmittelaufkommen erzielt – ist die Forschung an der Hochschule
der Medien breiter aufgestellt als je zuvor. Das zeigt sich
an zahlreichen neuen Projekten, welche im Berichtszeitraum
starteten. Der leichte Rückgang der Drittmittel im Berichtszeitraum
ist dem Auslaufen einiger großer Projekte geschuldet. Das
betrifft u.a. die kooperativen Promotionskollegs und gleichzeitig
auch – mit dem nahenden Ende von Horizon 2020 – EU-geförderter
Projekte. Zusätzlich trägt das Phänomen bei, dass bewilligte
Projekte verspätet bzw. langsamer als geplant starten. Der
Arbeitsmarkt in Stuttgart ist angespannt und nicht selten können
Stellen in Forschungsprojekten nur mit Verzögerung besetzt
werden. Hier steuert die Hochschule der Medien zukünftig mit
gezielter Personalentwicklung entgegen. Wissenschaftlichen Mitarbeiterinnen
und Mitarbeitern müssen gerade bei den üblichen
Projektbefristungen attraktive Weiterbildungs- und Entwicklungsmöglichkeiten
ermöglicht werden. Ein wesentlicher Pfeiler dazu
ist der Zugang zur Promotion. Die Anzahl der betreuten und
der abgeschlossenen Promotionen wächst stabil und gleichzeitig
bewährt sich die Strategie der Hochschule der Medien mit
vielfältigen Partnerschaften. Die Universitäten in Baden-Württemberg
haben inzwischen Satzungen für die Assoziierung von
Hochschullehrerinnen und Hochschullehrern der Hochschulen
für Angewandte Wissenschaften verabschiedet. Die Praxis zeigt
aber, dass es im konkreten Einzelfall gar nicht zu einer Assoziierung
kommt, da bereits eine individuelle Vereinbarung zu
Betreuung eines Doktoranden gefunden wurde. Somit setzen
wir weiterhin auf vielfältige Partnerschaften im In- und Ausland
und freuen uns, dass es hier u.a. mit Partnern in Australien neue
Vereinbarungen gibt, welche den diversen Forschungsthemen
gerecht wird.
Ein weiterer Indikator für die
Breite der Forschungsaktivitäten
an der Hochschule der
Medien ist das Ergebnis der
Neuausschreibung der Forschungsleuchttürme.
Mittlerweile
erfüllen 9 Institute die intern
festgelegten Kriterien, die
sich an den AG-IV orientieren.
Neu dazugekommen sind das
Learning Research Center, das
Institut für Games, das Institute for Applied Artifi cial Intelligence
und der Forschungsleuchtturm DECIDE (Digital Ethics, Responsible
Innovation and Design).
Neben der Förderung der Leuchttürme unterstützt die Hochschule
der Medien die forschenden Kollegen in Form von
Anschubstellen, individuellen Budgets für Tagungsteilnahmen
über das sog. Bonuspunkteprogramm, Deputatsnachlässen,
Forschungsprofessuren und durch die Schaffung von Rahmenbedingungen
und Planbarkeit. Ein weiterer Schritt wird der Aufbau
einer eigenen Ethikkommission sein sowie die Digitalisierung der
Unterstützungsprozesse der Forschenden.
Innerhalb des IAFs gab es Änderungen. Prof. Dr. Judith Papadopolus
folgt Prof. Dr. Michael Burmester sowohl als Prodekanin
der Fakultät Information & Kommunikation und Vertreterin
der Fakultät im Vorstand nach. Neben dem Dank an Michael
Burmester geht mein Dank vor allem an Alexandra Wenzel und
Marina Hudjec, welche als Team im IAF in vielfältiger Art und
Weise unsere forschenden Kollegen unterstützen.
Prof. Dr. Nils Högsda
Fare gli italiani con il design. La construcción del mito del Made in Italy (1945-1970).
“Fatta l’Italia, bisogna ‘fare’ gli italiani” fue el eslogan de la clase intelectual italiana ya desde las primeras fases de la recomposición geográfica y política del país, en la segunda mitad del siglo XIX: se refería al difícil desafío de construir una identidad compartida en una nación relativamente joven, unida por su secular tradición artística y cultural pero aún fragmentada por desequilibrios económicos y sociales. Esta construcción—paralela a la creación de una primera red productiva nacional—resulta ser un proceso largo y complejo, del que tanto el Risorgimento como las dos décadas fascistas constituyen etapas fundamentales; asimismo, las tres décadas sucesivas al segundo conflicto mundial revisten, en este sentido, una importancia igualmente crucial.
Esta propuesta tiene el objetivo de profundizar en el doble movimiento, a la vez centrífugo (hacia el extranjero) y centrípeto (hacia el interior y los propios italianos), con el que el diseño italiano contribuye a producir cierta imagen de la nación en unos años que, en relación a ello, han resultado
ser decisivos
Clausola d’emergenza e Costituzione.
Lunedì 4 e martedì 5 maggio 2020 si terrà il webinar “Stato di diritto - Emergenza - Tecnologia” sulla piattaforma Zoom. L’evento, organizzato dal Centro Ermes (European Research Centre on Media for E-Society), è nato da un’idea dei prof. Giovanna De Minico e Massimo Villone.
Il tema è quanta parte dello Stato di diritto sia stata congelata dall’emergenza e dalla tecnologia. Le misure limitative delle nostre libertà hanno rispettato la proporzionalità, la necessità, la temporaneità e la precauzionalità? L’autore del bilanciamento tra valori costituzionali è stato chi doveva essere? Come ha giocato l’erompere della tecnologia sull’effettività dei diritti fondamentali e sull’unità della Repubblica? Infine, emergenza e tecnologia cosa stanno insegnando a noi cittadini, allo Stato e all’Unione Europea
Spatial and egocentric mental rotation in patients with cervical dystonia
Mental rotation has attracted the interest of cognitive research on dystonia, but at the moment, contrasting data are available on whether this complex cognitive ability is impaired in the disorder. Here, we assessed spatial and egocentric mental rotation in patients with cervical dystonia (CD). Patients with CD and healthy controls were required to perform a letter rotation task (spatial mental rotation) and to judge laterality of front-facing and back-facing human images (egocentric mental rotation). CD patients were selectively impaired on letter rotation, whereas they did not differ from controls when judging laterality of both front-facing and back-facing bodies. These findings support the view according to which neural circuits involved in spatial processing are dysfunctional in CD