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    Isolation and Characterization of Lupeol from the Stem of Tapinanthus globiferus (A Rich.) and its Antimicrobial Assay

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    Lupeol, a pentacyclic triterpenoid, was isolated from hexane and ethyl acetate solvent system. In antiquity, the stem and leaf infusion of Tapinanthus globiferus has been used ethno-medicinally as a remedy for stomach ache, diarrhea, dysentery, and wounds. Lupeol isolation from this species was carried out by column chromatography after concentrating the crude extract using a rotary evaporator, and the structure was determined by analysis of the isolate by IR, 13CNMR, 1HNMR, HSQC, and HMBC spectral analysis as well as comparison with reported data. This is the first isolation of lupeol from the stem of this species

    Evaluation of Revenue Channels and Challenges in Sustainable Management of Oyo State Forest Reserves, Nigeria

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    Forest revenue system is an instrument used by government to achieve various goals and objectives in forest management. This paper evaluates the various challenges of revenue collection and remittance in Oyo forestry service in Nigeria. A total of 94 forest officials were identified and reached (100%) in all the forestry administrative zones in Oyo State, including the headquarters through a set of structured questionnaire and data obtained were analyzed using descriptive statistics and logit regression at \u3b10.05. Theaverage age of the respondents was 39.7\ub16.5 years, mostly male (71%), married (75.6%) and had secondary education (63%). Challenges confronting adequate revenue collection included lack of proper law enforcement, payment of cash by revenue collectors and inability of field officers to withstand armed illegal fellers with odds-ratio of 55694.85, 668.78 and 20.79 respectively. Problems facing adequate revenue remittance were remittance by field staff, inaccessibility of bank on time, lack of provision of incentives for running cost by the government and possibilities of field officers indulging in printing of fake receipts with odds-ratio of 140.18, 116.80, 3.65 and 3.44 respectively. The study exposed the various challenges facing adequate revenue collection and remittance in Oyo State forestry service, it is therefore necessary for the forest managers in the State to utilize this information wisely for the betterment of revenue generation

    Assessment of Biodiesel Fuel Potentials of Seed Crude Oil Extracts of Balanites aegyptiaaca (L.) Del

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    Study on assessmentof biodiesel fuel potentials of seed crude oil extracts of Balanites aegyptiaaca (L.) Del was carriedout. Standard methods of the Association of Official and Analytical Chemist (AOAC) were adopted to evaluate the proximate, physico-chemical properties and fatty acid compositions of crude seed oil extracts of the test plant. The proximate constituents of the crude seed oil extract gave crude protein (22.09%), crude fat (56.75%), moisturecontent (1.35%), ash (4.70%), crudefiber (12.75%) and carbohydrate (2.36%). The crude oil physicochemical properties included saponification value(216.439mgKOH/g), peroxide value(4.84meq/kg), acid value(2.18mgKOH/g), iodine value(77.08g/100g), viscosity value(150.3@30\ub0C) and cetane number(54.08), refractive index(1.487 @30\ub0C), relative density (0.949g/cm3) while calorific value was 39.03(MJ/kg). The fatty acids composition of crude kernel oil extract of B. aegyptiaca indicated the presence of four (4) fatty acids, with relative percentage abundance (RPA) in the order of 67.17% (9,12-Octadecanoic acid (C19H3402)) > 16.22% (Pentadecanoic acid (C17H3402)) > 11.8kg% (Heptacosanoic acid (C28H5602)) > 4.72% (Oleic acid(C18H3402)). These properties conferred relative prospects on the crude oil of the test plant as a suitable potential biodiesel substrate and consequently, large scale aforestation efforts be renewed, to guarantee ready availability of the raw materials

    A Critique on Sustainable Cities Waste Management Predicaments; Case of Nairobi City, Kenya

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    Waste management predicaments in attaining sustainable city status globally is challenged by increased solid waste generation as a result of rapid urban population and migration. Through a critique lens, solid waste management predicaments in developing countries characterized by inefficiencies; weak institutional capacities and lack of financial prudence. Nairobi City illustrates vividly predicaments through sporadic growth of open dumpsites, blocked drainers and sewers, indiscriminate behavior of littering. This is aided by weak enforcement of solid waste policies and regulations, duplicity of mandates by institutions and limited human resources. This paper undertakes to explicate predicaments in Nairobi City County and is supported by institutional, capacity and planned behavior theories. The study adopted mixed research design with data collection from a sample size of 385 household. Primary and secondary data was collected using questionnaires, key informant interview and focus group discussion; transect walk and desk top analysis. The results support the critique as documented by this paper. The study recommends institutional empowerment to reverse negative predicaments for sustainable global cities

    Assessment of Background Ionizing Radiation Dose Levels in Quarry Sites Located in Ebonyi State, Nigeria

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    The study presents a radiometric survey of Background Ionizing Radiation (BIR) dose levels in ten quarry sites located in Ebonyi State, Nigeria. In-situ BIR dose rate measurements, by means of nuclear radiation survey meter, at 1 m above ground level were carried out at the excavation section (ES) and quarrying section (QS) of the investigated quarry sites. The obtained results indicated dose rates ranging from from 0.14 to 0.18 \u3bcSv/h with mean of 0.15\ub10.01 \u3bcSv/h at the ES and 0.16 to 0.19 \u3bcSv/h with mean value of 0.18\ub10.01 \u3bcSv/h at the QS. While the values obtained at the QS are respectively higher than those measured at the ES, they are all higher than the worldwide average value of 84 nSv/h signifying BIR elevated environments. The estimated mean annual effective dose (AED) and excess lifetime cancer risk (ELCR) are 0.27\ub10.03 mSv/y and 0.94 710\u20133 respectively at the ES and 0.31\ub10.02 mSv/y and 1.07 710\u20133 at the QS. The obtained AED values for all the sites are well above the outdoor worldwide average value of 0.07 mSv/y but lower than the International Commission on Radiological Protection recommended permissible limits of 1.0 mSv/y for the general public. Generally, the BIR levels of the quarry sites are within acceptable limits and no immediate radiological health threat may be derived from the current levels. However, long-term health effects due to continuous exposure to low-level radiation doses may manifested in future over a lifetime exposure of 70 years as indicated by the ELCR values

    Efficacy of spraying intervals of Ridomil Plus 66 WP for control of taro leaf blight disease

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    Taro leaf blight causes up to 100% yield loss in susceptible taro ( Colocasia esculenta L. (Schott)) cultivars. The use of fungicides in disease management is fast and effective; however efficacy of fungicides could be affected by frequency of application. The objective of this study was to evaluate the efficacy of spraying intervals and economic benefits of Ridomil Plus 66 WP (12% Metalaxyl-M and 60% Copper (1) oxide) on taro leaf blight disease. The study consisted of four fungicide spraying intervals, viz at one, two and at four weekly intervals, all at the concentration of 3.3 g l-1 and no fungicide application as the control. Results showed no significant differences (P > 00.5) between one and two weekly spraying intervals in terms of taro leaf blight disease incidence and severity. These were, however, significantly different (P < 0.05) from four weekly and no fungicide applications. Taro corm yield was higher in weekly spraying interval, but not significantly different (P > 0.05) from biweekly application intervals. Yields in weekly intervals were 2.9, 33.0 and 44.0% higher than biweekly, four weekly and no application intervals. Applying fungicide at a biweekly interval was found to be economically efficient as it recorded higher total revenue and net present values. Applying 66 WP (12% Metalaxyl-M and 60% Copper (1) oxide) at 2 weekly interval was the optimum period and most efficient to reduce the incidence and severity of Phytophthora leaf blight disease and increase yield of taro.La br\ufblure des feuilles de taro peut causer une perte de rendement allant jusqu\u2019\ue0 100% chez les cultivars sensibles de taro ( Colocasia esculenta L. (Schott)). L\u2019utilisation de fongicides dans la gestion des maladies est rapide et efficace; cependant, l\u2019efficacit\ue9 des fongicides pourrait \ueatre affect\ue9e par la fr\ue9quence d\u2019application. L\u2019objectif de cette \ue9tude \ue9tait d\u2019\ue9valuer l\u2019efficacit\ue9 des intervalles de pulv\ue9risation et les avantages \ue9conomiques de Ridomil Plus 66 WP (12% de m\ue9talaxyl-M et 60% d\u2019oxyde de cuivre (1)) sur la maladie du taro. L\u2019\ue9tude consistait en quatre intervalles de pulv\ue9risation de fongicide, c\u2019est-\ue0-dire \ue0 une, deux, quatre intervalles hebdomadaires, le tout \ue0 la concentration de 3,3 g l-1 et sans application de fongicide. Les r\ue9sultats n\u2019ont montr\ue9 aucune diff\ue9rence significative (P> 00,5) entre un et deux intervalles de pulv\ue9risation hebdomadaires en termes d\u2019incidence et de gravit\ue9 de la br\ufblure du taro. Celles-ci \ue9taient cependant significativement diff\ue9rentes (P <0,05) de quatre applications hebdomadaires et sans fongicide. Le rendement en corme de taro \ue9tait plus \ue9lev\ue9 dans l\u2019intervalle de pulv\ue9risation hebdomadaire, mais pas significativement diff\ue9rent (P> 0,05) des intervalles d\u2019application bihebdomadaires. Les rendements \ue0 intervalles hebdomadaires \ue9taient de 2,9, 33,0 et 44,0% sup\ue9rieurs \ue0 ceux des deux semaines, quatre semaines et aucun intervalle d\u2019application. L\u2019application d\u2019un fongicide toutes les deux semaines s\u2019est av\ue9r\ue9e \ueatre \ue9conomiquement efficace car elle a enregistr\ue9 des revenus totaux et des valeurs actuelles nettes plus \ue9lev\ue9s. En conclusion, l\u2019application de 66 WP (oxyde de m\ue9talaxyl-M \ue0 12% et oxyde de cuivre (1) \ue0 60%) \ue0 intervalles de 2 semaines s\u2019est av\ue9r\ue9e \ueatre la p\ue9riode optimale et la plus efficace pour r\ue9duire l\u2019incidence et la gravit\ue9 de la maladie phytophthora et augmenter le rendement du taro

    New sources and stability of resistance to aphids in cowpea germplasm across locations in Uganda

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    The cowpea aphid ( Aphis craccivora Koch) is an economically important pest, whose feeding effects cause stunting, delayed flower initiation and yield reduction in cowpea ( Vigna unguiculata L. Walp). Host plant resistance offers an alternative for controlling aphids; while simultaneously reducing reliance on chemical pesticides. The objective of this study was to evaluate a multi-parent advanced generation inter-cross (MAGIC) population of cowpea against aphids, across cowpea growing regions in Uganda. The study was arranged in alpha lattice design, with two replicates in three locations over two seasons (2018B and 2019A). Results revealed significant effects (P<0.001) for the main treatment effects, genotype x location and location x season interaction for both infestation and damage. The genotype x season interaction was significant (P<0.01) for both aphid infestation and damage; while the three-way interaction was only significant (P<0.001) for aphid infestation, but not for damage. The study identified five new resistant and stable genotypes from the MAGIC panel, including MAGIC131, MAGIC-132, MAGIC149, MAGIC170 and MAGIC280; and one resistant parent, SUVITA-2. The study further revealed MAGIC-125, MAGIC-171, MAGIC153, MAGIC-333, MAGIC177, MAGIC-292, MAGIC282, MAGIC249, MAGIC162, SEC 4W * SEC 5T, NAROCOWPEA 4, MAGIC-204, MAGIC-039, MAGIC060, MAGIC-097, NAROCOWPEA 3, MAGIC-233, MAGIC090 and MU 9 to be moderately resistant and high yielding genotypes. The above genotypes are recommended for use in the cowpea breeding programme, to develop improved resistant lines against aphids in Uganda.Le puceron du ni\ue9b\ue9 ( Aphis craccivora Koch) est un ravageur \ue9conomiquement important, dont les effets alimentaires provoquent un retard de croissance, un retard de floraison et une r\ue9duction du rendement du ni\ue9b\ue9 ( Vigna unguiculata L. Walp). La r\ue9sistance des plantes h\uf4tes offre une alternative pour lutter contre les ravageurs destructeurs, y compris les pucerons; tout en r\ue9duisant simultan\ue9ment la d\ue9pendance aux pesticides chimiques. L\u2019objectif de cette \ue9tude \ue9tait d\u2019\ue9valuer une population multi-parentale inter-crois\ue9e de g\ue9n\ue9ration avanc\ue9e (MAGIC) de ni\ue9b\ue9 contre les pucerons, dans les r\ue9gions de culture du ni\ue9b\ue9 en Ouganda afin d\u2019identifier de nouvelles sources de r\ue9sistance contre le ravageur. L\u2019\ue9tude a \ue9t\ue9 organis\ue9e en conception de r\ue9seau alpha, avec deux r\ue9pliques \ue0 trois endroits sur deux saisons (2018B et 2019A). Les r\ue9sultats ont r\ue9v\ue9l\ue9 des effets significatifs (P <0,001) pour les principaux effets du traitement, le g\ue9notype x emplacement et l\u2019interaction emplacement x saison pour l\u2019infestation et les dommages. L\u2019interaction g\ue9notype x saison \ue9tait significative (P <0,01) \ue0 la fois pour l\u2019infestation et les dommages caus\ue9s par les pucerons; tandis que l\u2019interaction \ue0 trois facteurs n\u2019\ue9tait significative (P <0,001) que pour l\u2019infestation de pucerons, mais pas pour les dommages. L\u2019\ue9tude a identifi\ue9 cinq nouveaux g\ue9notypes r\ue9sistants et stables du panel MAGIC, notamment MAGIC131, MAGIC-132, MAGIC149, MAGIC170 et MAGIC280; et un parent r\ue9sistant, SUVITA-2. L\u2019\ue9tude a en outre r\ue9v\ue9l\ue9 MAGIC-125, MAGIC-171, MAGIC153, MAGIC-333, MAGIC177, MAGIC-292, MAGIC282, MAGIC249, MAGIC162, SEC 4W * SEC 5T, NAROCOWPEA 4, MAGIC-204, MAGIC-039, MAGIC060, MAGIC -097, NAROCOWPEA 3, MAGIC-233, MAGIC090 et MU 9 pour \ueatre des g\ue9notypes mod\ue9r\ue9ment r\ue9sistants et \ue0 haut rendement. Les g\ue9notypes ci-dessus sont recommand\ue9s pour une utilisation dans le programme de s\ue9lection du ni\ue9b\ue9 pour d\ue9velopper des lign\ue9es am\ue9lior\ue9es r\ue9sistantes aux pucerons en Ouganda

    EXPLORING CHALLENGES FACED BY PHYSICALLY DISABLED WOMEN IN UTILIZING ANTENAL SERVICES IN KABALE MUNICIPLAITY

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    Introduction: The right to utilize ANC services is included in Sustainable Development goals to improve maternal and neonatal health outcomes. According to Uganda MOH, every pregnant woman has got to attend four ANC visits in order to utilize the whole ANC package. Irrespective of the policy framework and laws that have been put in place for every pregnant woman to utilize antenatal care services from health care facilities, physically disabled pregnant women globally, and Uganda in particular, still underutilize ANC services from health care facilities. This is brought by challenges faced by Physically Disabled Pregnant Women (PDPW) when utilizing ANC services in health care facilities. Most studies on ANC services utilization are general rather than being specific to physically disabled pregnant women. Objectives: To investigate the extent of utilization of ANC services among physically disabled pregnant women (PDPWs) in health care facilities in Kabale Municipality between February, 2019 and February 2020. Methods: A purely qualitative method employing a descriptive phenomenological design was used. A sample 15respondents, both Physically Disabled Pregnant Women (PDPWs) and health workers were purposively selected and interviewed. Data was collected from 7PDPWs and 8 health workers using individual interviews, focus group discussion and observation. Data was transcribed and analyzed thematically. Results: The extent of utilization of ANC services by PDPWs is very low. This low ANC services utilization was due to challenges faced by PDPWs in attempt utilize ANC services from health care facilities. The revealed challenges were unmodified health care facilities, inadequate income, low levels of education among others. It was discovered that negative intra-personal attitudes of PDPW make them not to utilize ANC services from health care facilities. Inter-personal attitudes of health workers were quite positive and supportive towards ANC services by PDPW. Conclusion: There is low level of ANC services utilization among Physically Disabled Pregnant Women (PDPWs). This is mainly due to challenges they faced, in attempt to utilize ANC services, in health care facilities

    Bilateral paediatric cataract surgery - outcomes of 298 children from Kinshasa, the Democratic Republic of the Congo

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    Introduction: The leading cause of childhood blindness globally is paediatric cataract. Bilateral cataract surgery can help to improve visual performance and to diminish the burden of childhood blindness. Objective: To report in a retrospective observational cohort study the long-term outcomes of 298 children who had bilateral cataract surgery with IOL implantation from 2001-2016 in Kinshasa. Methods: A standardized surgical treatment of paediatric cataract was practiced on 298 children. Patient\u2019s follow-up, complications, and visual outcomes were recorded and analysed. Results: The mean age was 5.7 \ub1 4.3 years and males were predominant (64.9%). Most of children were living mainly in urban poorest areas (96.3%). Strabismus, nystagmus and microcornea were encountered in 20.1%, 25.1% and 8.7% of children, respectively. Using WHO criteria most of patients were classified as blind preoperatively and 81.9% of them had improved visual outcomes after surgery. Main reasons for reduced vision during follow-up were secondary cataract (5.7%), IOL decentration (1.2%), retinal detachment (1.2%), and secondary glaucoma (1.5%). Conclusion: In spite of the post conflict challenges, elimination of cataract blindness in children remains a priority. Children present at a late age for surgery and long term follow-up is poor. There is need for program strengthening in these areas

    Antiretroviral therapy outcomes among adolescents and young adults in a Tertiary hospital in Kenya

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    Background: Limited data is available on the treatment outcomes of HIV infected adolescents and young adults (AYA) in sub-Saharan Africa. HIV-infected adolescents and young adults (AYA) are at high risk of developing antiretroviral treatment failure. Objective: To determine the clinical, immunological and virologic outcomes of AYA at a tertiary hospital in Kenya. Methodology: A longitudinal study was conducted among AYA age 10-24 years attending Kenyatta National Hospital comprehensive care center. Clinical data was abstracted from electronic medical records for study participants with at least 6 months of follow-up using a structured data abstraction sheet. Results: A total of 250 AYA age 10 to 24 years were included. The median age was 16 years. The median CD4 cell count was 650.6 cells/mm3 (IQR 350.7-884.0). More than half (60.6%) of AYA had a CD4 cell count higher than 500 cells/mm3. Overall, 76.9% of AYA had achieved viral suppression (viral load <1000 copies/ml). There was a significant increase in virologic failure with higher age and late adolescents and young adults were more likely to have a viral load > 1000 copies/ ml p<0.012. Conclusion: The overall virologic suppression in this cohort of AYA was sub-optimal. Both immunological and virologic outcomes were worse among late adolescents (18-19 years) and young adults (20-24 years)

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