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Passive Smokers Pregnant Women with Low Birth Weight
No full textThe number of cases of low-birth-weight babies at dr. Doris Sylvanus Regional General Hospital, Palangka Raya in 2017 was as many as 378 cases. One of the causes of low birth weight was mothers who smoke actively or passively during pregnancy. The objective of this study is to determine the relationship between passive smoking pregnant women and the incidence of low birth weight at the dr. Doris Sylvanus Regional General Hospital, Palangka Raya. This research is an observational study using a cross-sectional research design and a retrospective approach with a sample of 45 mothers obtained using purposive sampling technique. Data analysis used Chi-Square statistical test. The results of the study found that pregnant women with heavy passive smokers gave birth to babies with low birth weight as many as 28 people (62.2%) and 1 person who did not have low birth weight babies (2.2%). Meanwhile, pregnant women with light passive smokers who gave birth to low birth weight were 12 people (26.7%) and 4 people did not have low birth weight (8.9%). Thus, there is a significant relationship between passive smoking pregnant women and the incidence of low birth weight at dr. Doris Sylvanus Regional General Hospital, Palangka Raya with p = 0.047, OR = 9.33. For further researchers, it is recommended to examine the factors that cause pregnant women to smoke passively with the incidence of low-birth-weight babies.The number of cases of low-birth-weight babies at dr. Doris Sylvanus Regional General Hospital, Palangka Raya in 2017 was as many as 378 cases. One of the causes of low birth weight was mothers who smoke actively or passively during pregnancy. The objective of this study is to determine the relationship between passive smoking pregnant women and the incidence of low birth weight at the dr. Doris Sylvanus Regional General Hospital, Palangka Raya. This research is an observational study using a cross-sectional research design and a retrospective approach with a sample of 45 mothers obtained using purposive sampling technique. Data analysis used Chi-Square statistical test. The results of the study found that pregnant women with heavy passive smokers gave birth to babies with low birth weight as many as 28 people (62.2%) and 1 person who did not have low birth weight babies (2.2%). Meanwhile, pregnant women with light passive smokers who gave birth to low birth weight were 12 people (26.7%) and 4 people did not have low birth weight (8.9%). Thus, there is a significant relationship between passive smoking pregnant women and the incidence of low birth weight at dr. Doris Sylvanus Regional General Hospital, Palangka Raya with p = 0.047, OR = 9.33. For further researchers, it is recommended to examine the factors that cause pregnant women to smoke passively with the incidence of low-birth-weight babies
Innovation of Dental X-Ray Holder Using Silicone Rubber Coating in Posterior Dental Periapical Intraoral Examination
No full textThe major drawback of the parallel periapical examination technique is that the holder used can damage the oral tissues and cause discomfort to the patient. The objective of this study is to determine the work efficiency and radiographic quality of the innovative dental x-ray holder which has been made by adding synthetic rubber or silicone to the part of the holder that is in direct contact with the patient. This research is an experimental with a post-test only design. The analysis was performed based on filling out the questionnaire on a Likert scale ranging from 1 to 4. With the criteria 1. Disagree, 2. Sometimes, 3. Agree and 4. Strongly Agree. The test was administered by comparing the holder made with the commonly used Aphrodite holder as a control group. There were 16 repetitions of exposure to the cadaveric skull in obtaining research data for each treatment group. The results of statistical work efficiency testing on the control group resulted in a value of B = 0.125 with a significance of 0.071 and an effect of 10.5%. Meanwhile, for testing the quality of radiographic image, the value of B = 0.125 with a significance of 0.014 and an effect of 18.5% was obtained. The innovative dental x-ray holder using a silicone rubber layer is efficient and the resulting radiographic image quality is good when used in the intraoral examination.The major drawback of the parallel periapical examination technique is that the holder used can damage the oral tissues and cause discomfort to the patient. The objective of this study is to determine the work efficiency and radiographic quality of the innovative dental x-ray holder which has been made by adding synthetic rubber or silicone to the part of the holder that is in direct contact with the patient. This research is an experimental with a post-test only design. The analysis was performed based on filling out the questionnaire on a Likert scale ranging from 1 to 4. With the criteria 1. Disagree, 2. Sometimes, 3. Agree and 4. Strongly Agree. The test was administered by comparing the holder made with the commonly used Aphrodite holder as a control group. There were 16 repetitions of exposure to the cadaveric skull in obtaining research data for each treatment group. The results of statistical work efficiency testing on the control group resulted in a value of B = 0.125 with a significance of 0.071 and an effect of 10.5%. Meanwhile, for testing the quality of radiographic image, the value of B = 0.125 with a significance of 0.014 and an effect of 18.5% was obtained. The innovative dental x-ray holder using a silicone rubber layer is efficient and the resulting radiographic image quality is good when used in the intraoral examination
The Prediction Number of Smear Acid Resistant Bacteria on Positive Pulmonary Tuberculosis Infection Disease at Madiun City in 2021 to 2025
No full textTuberculosis (TB) is an infectious disease caused by Mycobacterium Tuberculosis Bacillus. The disease spreads in the air when people contract TB bacteria, such as coughing or sneezing. The lack of ability to anticipate the incidence of Acid Resistant Bacteria Positive Pulmonary TB in Madiun City is affected by the time and number of events that have not been appropriately foreseen. There is no map of regional vulnerability based on the time of occurrence. Hence, the incidence of Acid Resistant Bacteria Positive Pulmonary TB in Madiun city increases, determined by the total number of cases in 6 health centers, seven hospitals, and one prison. In 2015, there were 174 cases, then in 2019, 706 cases. The objective of this study is to predict the number of Acid Resistant Bacteria Positive Pulmonary TB suffering in 2021-2025 based on gender, health centers, and prisons in Madiun City and the overall incidence of cases in 2015-2019 is then foreseen in 2021 to 2025. This type of research is descriptive study research by employing Eviews with the ARIMA method. The population and samples in the study were all data of Acid Resistant Bacteria Positive Pulmonary TB case encompassing the sex of patients during 2015-2019 in Madiun City. The study aimed to predict the incidence of Acid Resistant Bacteria Positive Pulmonary TB in 2021-2025. The results of this study revealed the projection of Acid Resistant Bacteria Positive Pulmonary TB cases based on gender, health centers, hospitals, and prisons in Madiun City from 2020-2025, which experienced an increasing trend with the number of 933, 992, 1063, 1120, 1190 incidences respectively. This study is recommended for relevant agencies or health services to perform preventive efforts by involving trained policymakers and Health Cadis, particularly in preventing TB disease and reducing the high rate of predicting positive pulmonary TB smear incidences in the future.Tuberculosis (TB) is an infectious disease caused by Mycobacterium Tuberculosis Bacillus. The disease spreads in the air when people contract TB bacteria, such as coughing or sneezing. The lack of ability to anticipate the incidence of Acid Resistant Bacteria Positive Pulmonary TB in Madiun City is affected by the time and number of events that have not been appropriately foreseen. There is no map of regional vulnerability based on the time of occurrence. Hence, the incidence of Acid Resistant Bacteria Positive Pulmonary TB in Madiun city increases, determined by the total number of cases in 6 health centers, seven hospitals, and one prison. In 2015, there were 174 cases, then in 2019, 706 cases. The objective of this study is to predict the number of Acid Resistant Bacteria Positive Pulmonary TB suffering in 2021-2025 based on gender, health centers, and prisons in Madiun City and the overall incidence of cases in 2015-2019 is then foreseen in 2021 to 2025. This type of research is descriptive study research by employing Eviews with the ARIMA method. The population and samples in the study were all data of Acid Resistant Bacteria Positive Pulmonary TB case encompassing the sex of patients during 2015-2019 in Madiun City. The study aimed to predict the incidence of Acid Resistant Bacteria Positive Pulmonary TB in 2021-2025. The results of this study revealed the projection of Acid Resistant Bacteria Positive Pulmonary TB cases based on gender, health centers, hospitals, and prisons in Madiun City from 2020-2025, which experienced an increasing trend with the number of 933, 992, 1063, 1120, 1190 incidences respectively. This study is recommended for relevant agencies or health services to perform preventive efforts by involving trained policymakers and Health Cadis, particularly in preventing TB disease and reducing the high rate of predicting positive pulmonary TB smear incidences in the future
Saliva pH Between Gargling and without Gargling Water after Consuming Sweet and Sticky Foods
No full textSweet and sticky foods are the main energy source for oral bacteria and are directly involved in lowering the pH. Gargling with boiled water after every meal can speed up the pH of the saliva in the mouth to return to normal. The objective of this study is to determine the difference in salivary pH between gargling and without gargling water after consuming sweet foods in elementary school students. The research method used was quasi-experimental with pretest and posttest with control group design. The instrument in this research was a pH meter. The population in this study were students in grades I – V of public elementary schools in Bantul with a total population of 135. The research sample used total sampling. Analysis of the research data was conducted using the Wilcoxon test, Mann Withney and Anova Test. The results showed that the pH of saliva (direct gargling) of water/0 minutes after consuming sweet and sticky foods was before 7.53 after gargling 7.99 increased by 0.46. The pH of gargling saliva 5 minutes before 7.48 after rinsing 7.63 increased 0.15. pH of saliva gargling 10 minutes, that was before 7.31 after gargling 7.3 decreased by 0.18. pH of saliva (without rinsing) water/0 minutes, which was initial pH 7.68 to 7.55 after consuming sweet and sticky foods, decreased 0 ,13. The pH of saliva without rinsing with water for 5 minutes, the initial pH was 7.70 to 7.06, decreased by 0.64. The most effective gargling time on salivary pH was gargling water immediately 0 minutes after consuming sweet and sticky foods. The time without gargling water affecting the pH of saliva after consuming sweet and sticky foods was 5 minutes.Sweet and sticky foods are the main energy source for oral bacteria and are directly involved in lowering the pH. Gargling with boiled water after every meal can speed up the pH of the saliva in the mouth to return to normal. The objective of this study is to determine the difference in salivary pH between gargling and without gargling water after consuming sweet foods in elementary school students. The research method used was quasi-experimental with pretest and posttest with control group design. The instrument in this research was a pH meter. The population in this study were students in grades I – V of public elementary schools in Bantul with a total population of 135. The research sample used total sampling. Analysis of the research data was conducted using the Wilcoxon test, Mann Withney and Anova Test. The results showed that the pH of saliva (direct gargling) of water/0 minutes after consuming sweet and sticky foods was before 7.53 after gargling 7.99 increased by 0.46. The pH of gargling saliva 5 minutes before 7.48 after rinsing 7.63 increased 0.15. pH of saliva gargling 10 minutes, that was before 7.31 after gargling 7.3 decreased by 0.18. pH of saliva (without rinsing) water/0 minutes, which was initial pH 7.68 to 7.55 after consuming sweet and sticky foods, decreased 0 ,13. The pH of saliva without rinsing with water for 5 minutes, the initial pH was 7.70 to 7.06, decreased by 0.64. The most effective gargling time on salivary pH was gargling water immediately 0 minutes after consuming sweet and sticky foods. The time without gargling water affecting the pH of saliva after consuming sweet and sticky foods was 5 minutes
Factors Associated with Providing the Basic Immunization to Infants
No full textBasic immunization is the first providing immunization to acquire the immune level on the verge of protection given to baby before one year which was aimed to get a full set of basic immunization for each baby with a good indicator that is full immunization (IDL). The indicator was influenced by several independent variables such as mother’s job status, education, knowledge, attitude, perception, and support from cadre and family. From total 89 villages in Lamandau district since 2015 to 2018, there were 82 villages of Universal Child Immunization (UCI) (92.1%) increased by 22.78% than 2016 is 69.32%. However, there was Drop Out (DO) of 2.83% from the village thathad not reached a full set of basic immunization of infants in Kujan Village. The objective of this study is to determine the factors associated with providing a full set of basic immunization of infants in Kujan village, Bulik district, Lamandau Regency, Central Kalimantan Province. The research employed cross sectional design. Data was collected from 80 mothers who had children aged 12-24 months during February 2020. The study samples was conducted with total sampling (80 respondents). The results of study used chi square test with levels of trust that is 95%. It showed a significant relationship between education by providing a full set of basic immunization of infants with p-value = 0.000. Meanwhile, employment status, knowledge, attitudes, family support, perceptions, support from cadres were not related to complete immunization. Therefore, based on the results of this study, it is suggested to the Lamandau Regency Government in the long term to improve the education of healthy mothers and also massive education related to the importance of immunization to increase the complete basic immunization coverage in Kujan Village.Basic immunization is the first providing immunization to acquire the immune level on the verge of protection given to baby before one year which was aimed to get a full set of basic immunization for each baby with a good indicator that is full immunization (IDL). The indicator was influenced by several independent variables such as mother’s job status, education, knowledge, attitude, perception, and support from cadre and family. From total 89 villages in Lamandau district since 2015 to 2018, there were 82 villages of Universal Child Immunization (UCI) (92.1%) increased by 22.78% than 2016 is 69.32%. However, there was Drop Out (DO) of 2.83% from the village thathad not reached a full set of basic immunization of infants in Kujan Village. The objective of this study is to determine the factors associated with providing a full set of basic immunization of infants in Kujan village, Bulik district, Lamandau Regency, Central Kalimantan Province. The research employed cross sectional design. Data was collected from 80 mothers who had children aged 12-24 months during February 2020. The study samples was conducted with total sampling (80 respondents). The results of study used chi square test with levels of trust that is 95%. It showed a significant relationship between education by providing a full set of basic immunization of infants with p-value = 0.000. Meanwhile, employment status, knowledge, attitudes, family support, perceptions, support from cadres were not related to complete immunization. Therefore, based on the results of this study, it is suggested to the Lamandau Regency Government in the long term to improve the education of healthy mothers and also massive education related to the importance of immunization to increase the complete basic immunization coverage in Kujan Village
The Effectiveness of Pineapple Extract (Ananas Comosus) and Kesum Leaves (Polygonus Minus) on the Quality of Coconut Oil (Coconus Nucifera)
No full textThe processed oil from the coconut plant is generally understood as coconut oil. A method is required to produce a product with a higher oil extraction rate and is able to reduce the water content and free fatty acids in the coconut oil production. It is also necessary to add substances that can delay or prevent fat oxidation reactions by generating substances in the form of antioxidants. The method that can be implemented is the enzymatic method employing the bromelain enzyme in a pineapple with the addition of an antioxidants substance from the kesum leaf. The objective of this research is to describe the quality of coconut oil after the addition of pineapple (ananas comosus) and kesum leaves (polygonus minus) extracts. The parameters for describing the quality of the oil are the organoleptic test, the degree of acidity, the oil extract rate, the peroxide number, the saponification number, and the acid number. This research is a quasi-experiment. The samples in this research were coconut oil without the addition of pineapple fruit extract, coconut oil with the addition of pineapple fruit extract without the addition of kesum leaves, and coconut oil with the addition of pineapple fruit extract and kesum leaves as much as 20gr, 30gr and 40gr. Based on the statistical results of the linear regression test, it was discovered that p-value = 0.000 <0.05, so it was concluded that there was an effect of the addition of pineapple fruit and leaves of kesum on acid number content with an effect of 76.4% on the acid number, 71.4% on the peroxide number, and 81.5% to the saponification number. It is recommended to test the water content, free fatty acids, and iodine number.The processed oil from the coconut plant is generally understood as coconut oil. A method is required to produce a product with a higher oil extraction rate and is able to reduce the water content and free fatty acids in the coconut oil production. It is also necessary to add substances that can delay or prevent fat oxidation reactions by generating substances in the form of antioxidants. The method that can be implemented is the enzymatic method employing the bromelain enzyme in a pineapple with the addition of an antioxidants substance from the kesum leaf. The objective of this research is to describe the quality of coconut oil after the addition of pineapple (ananas comosus) and kesum leaves (polygonus minus) extracts. The parameters for describing the quality of the oil are the organoleptic test, the degree of acidity, the oil extract rate, the peroxide number, the saponification number, and the acid number. This research is a quasi-experiment. The samples in this research were coconut oil without the addition of pineapple fruit extract, coconut oil with the addition of pineapple fruit extract without the addition of kesum leaves, and coconut oil with the addition of pineapple fruit extract and kesum leaves as much as 20gr, 30gr and 40gr. Based on the statistical results of the linear regression test, it was discovered that p-value = 0.000 <0.05, so it was concluded that there was an effect of the addition of pineapple fruit and leaves of kesum on acid number content with an effect of 76.4% on the acid number, 71.4% on the peroxide number, and 81.5% to the saponification number. It is recommended to test the water content, free fatty acids, and iodine number
Hemodialysis Duration with Levels of Hemoglobin, Hematocrit, Serum Iron and Total Iron Binding Capacity on Chronic Kidney Disease
No full textThe correlation of the length of time undergoing hemodialysis with the levels of hemoglobin, hematocrit, serum iron and total iron binding capacity in patients with chronic kidney disease at RSUD Prof. Dr. W. Z. Johannes Kupang. People with chronic kidney disease who are performing Hemodialysis suffer from anemia. Blood loss during the hemodialysis process is affected by frequent blood sampling for laboratory tests. To diagnose the occurrence of iron deficiency, anemia laboratory tests such as complete blood, serum iron (SI), TIBC, transferrin saturation, and serum ferritin can be conducted. The objective of this study is to determine the correlation between the length of undergoing Hemodialysis with the levels of Hemoglobin, Hematocrit, Serum Iron, and Total Iron Binding Capacity (TIBC) in patients with chronic kidney disease in RSUD Prof. Dr.W. Z Johannes Kupang. This study employed an anon-reactive research design or unobtrusive research based on secondary data derived from medical record records at RSUD Prof. Dr.W. Johannes in August - September 2019 on 92 hemodialysis patients who met the inclusion criteria. The collected data were calculated with the SPSS application, while the correlation analysis between variables was performed by administering a linear regression analysis test. Ninety-two (92) respondents were obtained by employing the purposive sampling technique. The majority of patients with chronic kidney disease undergoing Hemodialysis were men (57.6%) with ages 39 - 59 years (63.0%), and the majority of patients undergoing Hemodialysis in patients with chronic kidney failure (CKD) were <12 months (41.3%). It was discovered that there was no relationship between the length of Hemodialysis with hemoglobin, hematocrit, serum iron, and total iron-binding capacity levels in patients with chronic kidney disease (CKD).The correlation of the length of time undergoing hemodialysis with the levels of hemoglobin, hematocrit, serum iron and total iron binding capacity in patients with chronic kidney disease at RSUD Prof. Dr. W. Z. Johannes Kupang. People with chronic kidney disease who are performing Hemodialysis suffer from anemia. Blood loss during the hemodialysis process is affected by frequent blood sampling for laboratory tests. To diagnose the occurrence of iron deficiency, anemia laboratory tests such as complete blood, serum iron (SI), TIBC, transferrin saturation, and serum ferritin can be conducted. The objective of this study is to determine the correlation between the length of undergoing Hemodialysis with the levels of Hemoglobin, Hematocrit, Serum Iron, and Total Iron Binding Capacity (TIBC) in patients with chronic kidney disease in RSUD Prof. Dr.W. Z Johannes Kupang. This study employed an anon-reactive research design or unobtrusive research based on secondary data derived from medical record records at RSUD Prof. Dr.W. Johannes in August - September 2019 on 92 hemodialysis patients who met the inclusion criteria. The collected data were calculated with the SPSS application, while the correlation analysis between variables was performed by administering a linear regression analysis test. Ninety-two (92) respondents were obtained by employing the purposive sampling technique. The majority of patients with chronic kidney disease undergoing Hemodialysis were men (57.6%) with ages 39 - 59 years (63.0%), and the majority of patients undergoing Hemodialysis in patients with chronic kidney failure (CKD) were <12 months (41.3%). It was discovered that there was no relationship between the length of Hemodialysis with hemoglobin, hematocrit, serum iron, and total iron-binding capacity levels in patients with chronic kidney disease (CKD)
The Effect of Health Education on Mother\u27s Knowledge Attitudes and Behavior in Giving Care to Low Birth Weight Babies
No full textThe number of low-birth-weight babies (LBW) who returned to the hospital after returning home had increased from 2015 to 2016. The results of the interview revealed that mothers who had LBW did not thoroughly understand providing care for LBW after returning from the hospital. This study aims to determine the effect of health education on a mother\u27s knowledge, attitude and behaviour in providing care to LBW. This study is quasi-experimental with a pre-posttest approach non-equivalent to the control group, with 66 respondents fulfilling the inclusion criteria. The inclusion criteria in this study were post-partum mothers on the second day who had babies with a birth weight of 1500 grams-2499 grams and were willing to be respondents. The sampling technique was purposive sampling. The statistical test employed independent t-test, paired t-test, and chi-square. Knowledge scores before and after treatment were significantly different in the intervention group and control group, with a p-value in the intervention group 0.00, while the knowledge and attitude scores in the control group were 0.00 and the behavioural scores were 0.11. There was a significant difference in the increase in knowledge, attitudes and behaviour scores in both groups. The p-value of knowledge and attitudes is 0.00, and the p-value of behaviour is 0.01. Hence, there is an increase in mothers\u27 knowledge, attitudes, and behaviour after being provided with health education using a booklet.The number of low-birth-weight babies (LBW) who returned to the hospital after returning home had increased from 2015 to 2016. The results of the interview revealed that mothers who had LBW did not thoroughly understand providing care for LBW after returning from the hospital. This study aims to determine the effect of health education on a mother\u27s knowledge, attitude and behaviour in providing care to LBW. This study is quasi-experimental with a pre-posttest approach non-equivalent to the control group, with 66 respondents fulfilling the inclusion criteria. The inclusion criteria in this study were post-partum mothers on the second day who had babies with a birth weight of 1500 grams-2499 grams and were willing to be respondents. The sampling technique was purposive sampling. The statistical test employed independent t-test, paired t-test, and chi-square. Knowledge scores before and after treatment were significantly different in the intervention group and control group, with a p-value in the intervention group 0.00, while the knowledge and attitude scores in the control group were 0.00 and the behavioural scores were 0.11. There was a significant difference in the increase in knowledge, attitudes and behaviour scores in both groups. The p-value of knowledge and attitudes is 0.00, and the p-value of behaviour is 0.01. Hence, there is an increase in mothers\u27 knowledge, attitudes, and behaviour after being provided with health education using a booklet
The Effect of Simplisia Drying Method on Antioxidant Activity of Senggani Fruit Extract (Melastoma Malabathricum L.) by DPPH (2,2-diphenyl-1-picrylhydrazyl)
No full textSenggani fruit (Melastoma Malabathricum L.) contains anthocyanin that functioning as an antioxidant. Anthocyanin are tremendously sensitive to thermal processes which trigger phytochemical or photo-oxidation reactions that can open anthocyanin rings. The objective of this study is to identify the effect of the simplicia drying method on the antioxidant activity of Senggani fruit extract. Senggani fruit extract was prepared by obtaining samples of ripe fruit, dry sorting, washing, wet sorting, and drying using two methods; sunlight and oven at 70oC. After the simplicia was dry, it was blended and sifted until smooth. The fine simplicia was macerated with 96% ethanol and evaporated to gain a crude extract. The crude extract was assessed with reagents for phytochemical screening. Furthermore, the crude extract was examined for antioxidant activity by the DPPH method. This study implies that the simplicia and crude extract of Senggani fruit from drying in sunlight and oven possess different organoleptic properties such as color, smell, and taste. In phytochemical testing with reagents, it was discovered that anthocyanin compounds were unveiled in drying utilizing sunlight while employing an oven at 70oC; no anthocyanins were found. The antioxidant testing of Senggani fruit extract revealed that the drying method employing sunlight had an IC50 value of 18.8 g/mL while the oven temperature of 70oC owned an IC50 value of 28.3 g/mL. Based on the study results, it can be identified that the simplicia drying method affects the antioxidant activity of the Senggani fruit extract. The drying method in the sun produces extracts with greater antioxidant activity while drying in an oven at 70oC results in a degradation process of anthocyanin compounds, thereby decreasing the antioxidant activity of the Senggani fruit extract.
Senggani fruit (Melastoma Malabathricum L.) contains anthocyanin that functioning as an antioxidant. Anthocyanin are tremendously sensitive to thermal processes which trigger phytochemical or photo-oxidation reactions that can open anthocyanin rings. The objective of this study is to identify the effect of the simplicia drying method on the antioxidant activity of Senggani fruit extract. Senggani fruit extract was prepared by obtaining samples of ripe fruit, dry sorting, washing, wet sorting, and drying using two methods; sunlight and oven at 70oC. After the simplicia was dry, it was blended and sifted until smooth. The fine simplicia was macerated with 96% ethanol and evaporated to gain a crude extract. The crude extract was assessed with reagents for phytochemical screening. Furthermore, the crude extract was examined for antioxidant activity by the DPPH method. This study implies that the simplicia and crude extract of Senggani fruit from drying in sunlight and oven possess different organoleptic properties such as color, smell, and taste. In phytochemical testing with reagents, it was discovered that anthocyanin compounds were unveiled in drying utilizing sunlight while employing an oven at 70oC; no anthocyanins were found. The antioxidant testing of Senggani fruit extract revealed that the drying method employing sunlight had an IC50 value of 18.8 g/mL while the oven temperature of 70oC owned an IC50 value of 28.3 g/mL. Based on the study results, it can be identified that the simplicia drying method affects the antioxidant activity of the Senggani fruit extract. The drying method in the sun produces extracts with greater antioxidant activity while drying in an oven at 70oC results in a degradation process of anthocyanin compounds, thereby decreasing the antioxidant activity of the Senggani fruit extract
Measuring the Antioxidant Effect of Limnocharis Flava on Malondialdehyde Activities in Livers of Alloxan-induced Diabetic Rats
No full textAntioxidants are substances counteracting the effects of free radicals. Antioxidants are formed in several forms, encompassing vitamins, minerals, and phytochemicals. Genjer or yellow velvet leaves (Limnocharis Flava) is an aquatic plant potentially beneficial alternative to natural antioxidants. This study aims to measure the antioxidant effect from the yellow velvetleaf ethanol extract on malondialdehyde (MDA) activities in livers of diabetic rats (Rattus novergicus) induced by alloxan in three different doses. The tested animals were randomly divided into five groups comprising six white rats previously induced with alloxan by intra-peritoneal injection. Group 1 was the negative control provided 0.5% CMC Na while group 2 was a positive control administered 0.45 mg glibenclamide. On the other hand, groups 3, 4, and 5 were the experimental groups that provided the extract of yellow velvetleaf as many as 32.5 mg/kg body weight (BW) ethanol, 65 mg/kg BW ethanol extract, and 130 mg/kg BW, respectively. Furthermore, the extracts were administered once on the 7th, 14th, and 21st days; the parameters observed were MDA activities in the rats’ livers. The Thiobarbituric Acid Reactive Substances (TBARs) method was then employed to investigate these actions. The one-way ANOVA was administered to examine the acquired data from the examination, followed by a post hoc test. The average points of the MDA level from group 1 to group 5 were 10.78 0.33, 3.71 + 0.19, 7.25 + 0.26, 5.76 + 0.25, and 4.01 + 0.22, correspondingly, according to the results. The one-way ANOVA test revealed that MDA levels in each test group were significantly different (p 0.05). Based on these findings, it may be concluded that feeding ethanol extract from yellow velvet leaves to diabetic rats reduces MDA levels in their livers, therefore preserving cells from harm.Antioxidants are substances counteracting the effects of free radicals. Antioxidants are formed in several forms, encompassing vitamins, minerals, and phytochemicals. Genjer or yellow velvet leaves (Limnocharis Flava) is an aquatic plant potentially beneficial alternative to natural antioxidants. This study aims to measure the antioxidant effect from the yellow velvetleaf ethanol extract on malondialdehyde (MDA) activities in livers of diabetic rats (Rattus novergicus) induced by alloxan in three different doses. The tested animals were randomly divided into five groups comprising six white rats previously induced with alloxan by intra-peritoneal injection. Group 1 was the negative control provided 0.5% CMC Na while group 2 was a positive control administered 0.45 mg glibenclamide. On the other hand, groups 3, 4, and 5 were the experimental groups that provided the extract of yellow velvetleaf as many as 32.5 mg/kg body weight (BW) ethanol, 65 mg/kg BW ethanol extract, and 130 mg/kg BW, respectively. Furthermore, the extracts were administered once on the 7th, 14th, and 21st days; the parameters observed were MDA activities in the rats’ livers. The Thiobarbituric Acid Reactive Substances (TBARs) method was then employed to investigate these actions. The one-way ANOVA was administered to examine the acquired data from the examination, followed by a post hoc test. The average points of the MDA level from group 1 to group 5 were 10.78 0.33, 3.71 + 0.19, 7.25 + 0.26, 5.76 + 0.25, and 4.01 + 0.22, correspondingly, according to the results. The one-way ANOVA test revealed that MDA levels in each test group were significantly different (p 0.05). Based on these findings, it may be concluded that feeding ethanol extract from yellow velvet leaves to diabetic rats reduces MDA levels in their livers, therefore preserving cells from harm