Jurnal Info Kesehatan
Not a member yet
478 research outputs found
Sort by
Effectiveness of Bay Leaves (Syzygium polyanthum) to Reduce Body Mass Index Among Pre-Menopausal Obese Adults in South Jakarta Regency
No full textPerimenopause is a transition phase towards menopause which is characterized by hormonal changes, including a decrease in the production of the hormone estrogen and an increase in belly fat which can cause obesity. This study aimed to examine the effectiveness of bay leaves to reduce body mass index (BMI). The research design used was quasi-experimental with a one-group pretest and posttest-only design. The population in this study were pre-menopausal adults with obesity who were selected using purposive sampling with a total respondents 30 adults. During 14 days, they are given the 4-5 bay leaves which were previously boiled with around 250 ml water. The BMI was calculated before and after giving the intervention. Data analysis used the Wilcoxon analysis test. The results revealed that there are significantly reduced BMI compared to before and after the intervention. The content of bay leaves can accelerate weight loss in pre-menopause because it has a thermogenic effect on the body and can be used as an alternative herbal therapy that is very easy to obtain and economical which can be used by obese women in perimenopause. The health promotion to introduce bay leaves could be started as bay leaves are easy to find and grow.
Development of an Early Detection Tool for Pneumonia in Toddlers with Ari Program Respiratory Rate Timer Based on the Internet of Things
No full textDelays in establishing a diagnosis of pneumonia in toddlers can increase toddler morbidity and mortality. Early pneumonia detection tools are very necessary to be able to provide appropriate intervention. The objective is to develop an early-detection tool for pneumonia in toddlers using the ARI Programme Respiratory Rate Time based on the Internet of Things by calculating respiratory frequency and oxygen saturation. The research methods use Research and Development (R&D) was carried out on toddlers with cough complaints in the working area of the Grogol Health Center, Sukoharjo Regency from December 2023 to January 2024. The sample consisted of 100 toddlers who were selected using consecutive sampling. The dependent variables are respiratory frequency and oxygen saturation. The independent variables are ARI based on IoT, ARI Timer, and pulse oximeter. Other data is collected through observation sheets. Data were analyzed using independent t-test analysis using the SPSS version 26. The results of the validation test assessment by 6 experts obtained a total average score of 95.48% with very valid assessment criteria, which means the tool is suitable for use. The results of the Independent T-Test show that there is no difference between IoT-based ARI (Mean=39.28; SD=9.05) and Timer ARI (Mean±SD= 39.29±9.07), this result is not statistically significant (p=0.994) and does not exist. the difference between IoT-based ARI (Mean±SD= 94.90±2.55) and pulse oximeter (Mean±SD= 95.15±2.61), this result is not statistically significant (p=0.494). The conclusion is an ARI Programme Respiratory Rate Timer based on the Internet of Things tool can be developed for the early detection of pneumonia in toddlers and is suitable for use to determine the respiratory frequency and oxygen saturation in toddlers
Mercury Pollution from Ilegal Gold Mining Activities and Its Impact on Human Health in the Anahoni River, Kaiely Bay, Maluku: A Review
No full textIllegal gold mining in the Anahoni River area, Kaiely Bay, Maluku, intensifies mercury pollution, posing grave environmental and health risks. Statistical analyses reveal a significant correlation between illegal mining and escalating mercury levels, necessitating urgent intervention. Environmental impacts include biomagnification in fish, affecting indigenous communities dependent on these resources. Health risks encompass neurological, reproductive, and respiratory implications, warranting targeted public health interventions. Examining the broader context, the global dimension of mercury pollution underscores the interconnected nature of the issue, requiring collaborative efforts. The toxicological aspects of mercury and its biogeochemical cycling inform potential mitigation strategies. Methodologically, systematic literature reviews, field investigations, and socio-economic assessments provide a holistic understanding of mercury contamination. Results highlight alarming mercury concentrations, with significant correlations between mercury levels, deforestation, and fish abundance, emphasizing the need for evidence-based policy decisions. Human health implications are evident through a positive correlation between mercury concentrations in river water and human hair samples, emphasizing the direct link between environmental exposure and health risks. Environmental impacts extend beyond human health, affecting ecosystems and necessitating global collaboration. The study underscores the importance of comprehensive policy frameworks, international collaborations, and community engagement in addressing the socio-economic roots of illegal gold mining. Mitigation strategies encompass regulations, sustainable practices, alternative technologies, and community-based initiatives. This review contributes to a nuanced understanding of mercury pollution in the Anahoni River, providing insights into the interconnected challenges and opportunities for sustainable solutions within a concise framework
The Glycemic Index of Gayam (Inocarpus fagifer Forst) Cookies as a High Dietary Fiber Food
No full textThe type 2 diabetes (T2D) is still one of the world\u27s public health problems. It needs serious handling and prevention efforts in the nutritional aspect. The high prevalence of T2D is related to the low intake of dietary fiber. This type of food has a low glycemic index (GI). Gayam is a high-dietary fiber material that can be used for the manufacture of flour and as processed food material for the high-dietary fiber cookies. The objectives of this research were to study the GI evaluation of cookies from gayam flour. Cookies were tested for chemical composition, and glycemic index. The glycemic index evaluation test used 12 volunteers taken from the healthy group/nondiabetic, normal nutritional status (BMI: 18.5-22.9), and age 19-55 years. The results of this study indicate the dietary fiber content of gayam cookies was 4.57 g/100 g and included in the category of high dietary fiber food. The glycemic index of gayam cookies was 43 and the low glycemic index category. The obtained results show for the first time the potential of gayam cookies in hyperglycaemia management. The conclusion of this study was that gayam cookies has high dietary fiber content and low GI level. Gayam cookies can be used as an alternative snack to control blood glucose levels in the prevention of diabetes mellitus.
Early MP-ASI Supplementation Impact in Infants and Toddlers Aged 6 to 24 Months
No full textThe highest rate of solid or semi-solid feeding occurs at the age of 4-5 months in 32.7% of the 488 sample children, according to data from the Indonesian Demographic and Health Survey, and the highest rate of early supplementation of drinking occurs at 2-3 months in 24.7% of the 506 sample children. This research also continues the results of previous research, where the research was to determine the dominant factors in giving MP-ASI to babies and toddlers. The research results were obtained from 132 babies and toddlers, of whom 44 (33.3%) had received early MP-ASI. This study aimed to determine the effect of early complementary feeding on growth and development in infants and toddlers aged 6–24 months in the Banjar Baru PKM area, Tulang Bawang Regency, in 2022. This type of research is retrospective with stratified random sampling, with a sample of 132 mothers with infants and toddlers aged 6–24 months. Bivariate analysis using the Chi-Square test and multivariate analysis with the Logistics Regression Test. The results of the study showed that more than half, namely 62.1% of respondents, were in favor of giving early complementary feeding to infants and toddlers in the risk category in the work area of the Banjar Baru Health Center, Tulang Bawang Regency, in 2022. The statistical test results also found that there was a significant effect between the behavior of giving MP to infants and toddlers with growth (p-value = 0.0001, OR = 3.273) and development (p-value = 0.000, OR = 10.353) in the Banjar Baru Public Health Center, Tulang Bawang Regency in 2022. In order to prevent early complementary feeding in infants and toddlers, it is suggested that pregnant women be educated about the effects of early complementary feeding on their children\u27s growth and development from 6 to 24 months of age. reactivating the role of Integrated Service Post (Posyandu) and health cadres in community activities for early detection of growth and development of infants and toddlers, identifying anomalies early so they can immediately receive referrals for treating developmental disorders in infants and toddlers in the Banjar Baru health center, Tulang Bawang district, in 2022.
The Flavonoids, Phenolics, and Antioxidant Activity from Ethanol Extract of Fibraurea tinctoria Lour
No full textOxidative stress has long been associated with increased risk for several diseases. Antioxidant is a molecule that inhibits the oxidation of other molecules and delays or prevents oxidative damage. Natural phenolic and flavonoid compounds are plant secondary metabolites directly contributing to antioxidant activity. Fibraurea tinctoria Lour, often called the yellow root, is a plant that has long been known in the traditional medicine of the native tribes of West Kalimantan to treat several diseases, including malaria, jaundice, and diabetes. This study aimed to quantify the total phenolic (TPC) and flavonoid (TFC) contents and antioxidant activity of the ethanol extract of yellow root stems. Yellow root stems were extracted by maceration in 96% ethanol for four days. The total phenolic, flavonoid, and antioxidant activities were measured using the Folin-Ciocalteu, AlCl3, and DPPH methods. Phytochemical screening showed that the ethanol extract of yellow root stems contains phenolics, flavonoids, alkaloids, saponins, tannins, and steroids/triterpenoids. The total phenol and flavonoid contents were 40.2 mg GAE/g extract and 61.2 mg QE/g extract, respectively. The ethanol extract of yellow root stems showed moderate DPPH scavenging activity, with an IC50 of 152.13 ppm. From this study, it can be concluded that this plant could be a potential source of natural antioxidants
Effect of pH Variations in Eosin Methylene Blue Agar (EMBA) Medium on E. coli Growth
No full textThe growth of E. coli is influenced by several factors, including environmental pH. Environmental pH unsuitable for bacterial growth conditions will interfere with the enzyme activity and influence bacterial growth. This study aimed to determine the effect of pH variations (5.3, 5.8, 6.3, 7.3, 7.8, 8.3) in EMBA medium on E. coli growth. The research method used was true experiment post-test-only control design. The samples in this study were suspensions with dilutions of 10-4, 10-5, 10-6, and 10-7, inoculated using the duplo test to EMBA with various pH conditions, so that the total sample size is 48. The results showed that the mean number of E. coli bacteria on EMBA with pH 5.3 was 9.1 x 106 CFU/mL; with pH 5.8 was 9.6 x 106 CFU/mL; with pH 6.3 was 1.2 x 107 CFU/mL; with pH 7.3 was 1.1 x 107 CFU/mL; with pH 7.8 was 9.7 x 106 CFU/mL; and with pH 8.3 was 7.1 x 106 CFU/mL. Growth in positive control showed the mean number 1.4 x 107 CFU/mL; negative control showed no growth of E. coli or other microorganisms. Based on the One-Way ANOVA statistical test with a 95% confidence level, there was no difference in the mean number of E. coli bacteria in the six pH variations of EMBA medium (p-value > 0.05). E. coli bacteria grew best at neutral pH. Its growth decreases in slightly acidic and slightly alkaline pH, but it can still be observed. This allows E. coli to survive in extreme pH. Pathogenic E. coli have developed the potential to live inside the human body. They will experience temporary stress in unfavourable conditions before finally adapting. The advice for future researchers is to test the effect of pH on E. coli growth by using other E. coli growth media or with a wider range of pH (more acidic and more basic). It is also recommended to conduct further research about the effect of various environmental conditions such as temperature, nutrients, and others on bacterial growth
The Effect of Preeclampsia in Pregnant Women on The Incidence of Maternal Mortality: Literature Review
No full textPreeclampsia is a severe pregnancy complication characterized by elevated blood pressure and often occurs after 20 weeks of gestation. This condition can lead to significant morbidity and mortality for both the mother and the fetus. This study aims to identify the risk factors associated with preeclampsia in pregnant women, a condition that remains prevalent in Indonesia and globally. The research employed a comprehensive literature review method, examining ten articles sourced from databases such as Google Scholar, PubMed, and Elsevier. The inclusion criteria for the literature review involved studies focused on the causes and consequences of preeclampsia, published within the last ten years, and providing substantial data on maternal mortality. The results of the literature review indicated that pregnant women with a history of hypertension or previous preeclampsia are at a significantly higher risk of developing preeclampsia. Additionally, severe cases of preeclampsia, such as those involving HELLP syndrome, eclampsia, and high diastolic blood pressure, were strongly linked to increased maternal mortality. The review also highlighted the crucial role of efficient referral systems and timely medical interventions in managing severe preeclampsia and reducing maternal deaths. This study concludes that early detection and continuous monitoring are essential for managing preeclampsia effectively. The findings underscore the need for standardized treatment protocols, improved healthcare access, and comprehensive prenatal services to mitigate the risks associated with preeclampsia. Future research should aim to include a broader range of studies and explore the long-term implications of preeclampsia on maternal and fetal health. These insights are critical for developing effective strategies to reduce the incidence and severity of preeclampsia and enhance maternal health outcomes.
Moringa oleifera as Anticancer: A Review of Recent Studies
No full textMoringa oleifera Lam (MO) plants have long been reported to have many pharmacotherapy benefits. In vitro and in vivo studies have shown that MO extracts have various biological activities and therapeutic effects, including cardioprotective, cardiometabolic, hypocholesterolemic, neuroprotective, anti-inflammatory, antioxidant, anti-hypertensive, anti-diabetic, anti-bacterial, immunomodulatory and anticancer. Researchers have tested extracts from various parts of the MO tree, both in vitro and in vivo, on several types of cancer (such as liver cancer cells, breast cancer, colorectal, leukemia, lung cancer, and oral cancer) with varying success. This review aims to explore the current state of the latest anticancer activity research of MO plants in the last five years. We tried to explore the anticancer activities of MO extracts from reported in vivo and in vitro studies. We searched systematically from three databases (PubMed, Scopus, and Embase) and summarized the data. The keywords used were “Moringa oleifera” AND “anticancer” AND “in vivo” OR “in vitro”. The inclusion criteria were in vivo or in vitro experimental studies and exclusion criteria analyses i.e., in silico trials, study protocols, reviews, or observational studies. This review includes 16 papers on nonclinical studies of MO anticancer activity. Several active compounds have been purified and have reported their anticancer effectiveness, including glucomoringin-ITC/MIC-1, 7-octanoic acid, oleamide, 1-phenyl-2-pentanol, quercetin, gallic acid, p-coumaric acid, and 4-hydroxy 3 – methoxy cinnamic acid, quinic acid. There was no difference in the mechanism of anticancer action based on plant parts, leaves, roots, and seeds, even though using different extraction methods. The general mechanism of action shown was apoptotic, antiproliferative, and cytotoxic. The dose used differed depending on the type of cancer cells used. Some used conventional extraction methods, and others have used modern techniques to extract the purified active compounds from the fractionation process. Our review made it clear that MO could be an excellent and safe candidate for the development of novel therapies against cancer and was most commonly reported in MCF-7, HepG2, and HCT-116 cancer cells. In addition, the development of MO products as future cancer prevention is also interesting to be explored and developed optimally in clinical settings.
Factors Associated with Anemia in Adolescents and Its Prevention Strategies: Systematic Review
No full textAnemia is a global health issue affecting various age groups, including teenagers. This systematic review aims to identify the causes and treatments of anemia in adolescents. Using the Systematic Literature Review method, data were sourced from four databases: PubMed, Science Direct, Google Scholar, and SCOPUS. The literature search employed the keywords "Risk factor" AND "Anemia" AND "Adolescence," conducted comprehensively via the Publish or Perish (POP) search engine. Articles were selected based on inclusion criteria, covering publications from the last three years (2021-2023). Eligibility was assessed using the PICOS framework, and duplications were filtered using the Covidence application. Articles unrelated to the research problem were excluded after screening titles and abstracts. The VOSviewer application was utilized for thematic mapping. The study selection followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Based on 18 selected articles, data was obtained on factors influencing anemia among adolescents such as inadequacy of nutrient intake (N=5 studies) such as protein, iron, and Vitamin A Nutritional status (N=3 studies), dietary patterns (N=2 studies), menstruation (N=2 studies), and hemoglobinopathies (N=1 study) are translated into English. Indirect risk factors associated with anemia among adolescents are found to be: Adolescent females (N=10 studies), Knowledge (N=6 studies), low socioeconomic status (N=3 studies), Education (N=2 studies), Demographics (2 studies), Shared toilet usage (1 study). The study concludes that young women are more susceptible to anemia than young men, with nutritional intake, knowledge, nutritional status, and diet being the primary risk factors. Addressing direct and indirect causes is crucial for effectively managing adolescent anemia.