Jurnal Pendidikan Kimia
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Ethnochemistry Study of The Use of Plants as Traditional Medicine In The Community of Samadua District, South Aceh Regency
Research on the ethnochemistry study of using plants as traditional medicine in the Samadua District community has been conducted. In general, there are two ways to use plants as medicine: internal medicine (oral) and external medicine (topical). This type of research is descriptive qualitative with an ethnographic approach that aims to determine the types, benefits, processing methods, and chemical content of plants used as internal medicine by the people of Samadua District. Data collection techniques in this study were observation, interviews, and documentation. The sampling technique was carried out by purposive sampling, namely by conducting interviews with herbal practitioners, community leaders, and users. The results showed that in Samadua District, 54 plants were used by the community to treat diabetes, high blood pressure, cough, gout, cholesterol, diarrhea, and other complaints. Medicinal plants are processed by boiling, grinding, kneading, eating, making juice, or brewing. The most processing method is boiling at 46.34%, while the least is brewing at 1.21%. Plants can be used as drugs because they contain certain chemicals produced from secondary metabolites. The chemical constituents of these medicinal plants include flavonoids, alkaloids, saponins, tannins, terpenoids, phenolic compounds, glycosides, vitamins, steroids, and essential oils. Ethnochemistry studies combine public opinion with science regarding the effectiveness of plants considered useful as drugs based on the chemical compounds contained in these plants
Integration Method of Religious Character Values in Chemistry Learning
Science and religion are closely related because they come from one source, namely God Almighty. Therefore, the concept of the integration of science and religion must be implemented in the form of integrating religious characters in the science learning process. This study aims to identify and inventory the learning methods used to integrate religious character values in chemistry learning. This research is conducted by reviewing the literature, both in books, journal articles and popular scientific writings, about methods of integrating religious character values in chemistry learning. The main data sources are from journal articles that discuss the integration of religious characters in chemistry learning. The journal articles that became the main data source were ten articles obtained from the Google Scholar website using the keyword "integration of religious characters in chemistry learning". The research data were analyzed descriptively and qualitatively. A critical study was also carried out on the literature to obtain the correct conclusion. According to the teacher's creativity, the study results concluded that religious character values can be integrated in chemistry learning in various ways/methods. However, in their article, the researchers did not clearly and unequivocally mention the name of the learning method used to integrate religious characters in chemistry learning. Based on this conclusion, it is recommended that other research is needed to develop a learning model that integrates religious character values in chemistry learning.
Study of Virtual Molecular Docking of Avocados Compounds against Pseudomonas aeruginosa (5N5H) by Carbapenemase using DOCK 6 Algorithm
Antimicrobial resistance from bacteria is a global health problem that can cause death, and the cause is the emergence of carbapenem resistance Pseudomonas aeruginosa through VIM (Verona integron-encode metallo-β-lactamase), which causes the carbapenem class of antibiotics not to work properly. This species is a gram-negative bacteria which is the main cause of nosocomial pneumonia infection. This study aims to determine in silico inhibitory activity of 50 compounds obtained from avocado (Persea Americana Mill) on VIM, preventing carbapenem antibiotic resistance. The molecular docking process was carried out to test carbapenem's antibiotic resistance control activity by 50 compounds. Docking using DOCK 6 software with a flexible and rigid method, Molecular docking on a protein with PDB ID 5N5H, The target protein was prepared using the Chimera application. Visualization of ligand-protein interactions was carried out with PyMOL and PLIP. The results of the native ligand grid score obtained by each method are -63.013 kcal/mol (Flexible) and -64.032 kcal/mol (Rigid). The best test ligands in the flexible method are 44257090, 14282775 and 44257819, and the grid score are -77.474, -75.274 and -73.219 kcal/mol. The best test ligands in the rigid method are 5280637, 14282775 and 5490064; the grid score is -62.191, -61.714, and -60.453 kcal/mol. The results of the test ligands can provide a better grid score than native ligands, namely in the flexible method. However, the rigid method of grid score results is no better than the native ligand. A good result is that the test ligand grid score is smaller than native ligands, so it has less energy to bind to the active site
Implementation of The Video Project with Distance Learning on The Basic Chemistry Course
Education in the 4.0 era encourages the use of digital technology in a sustainable learning process. This article tries to analyze student responses to implementing a video project in a basic chemistry course. This research is qualitative research with a survey method. The participants were 74 students of the Chemistry Education Study Program and Mathematics Study Program consisting of 8 male students and 66 female students. Data collection techniques using online questionnaires by google form application. The steps in this study are Search for instrument literature to be compiled on the google form, compile a google form student response to the implementation of the video project, distribute the google form questionnaire link to students, and analyze the data obtained. The results showed that students positively responded to the implementation of the video project in terms of autonomy, teamwork, and technology used. The implementation of video projects improves learning skills, collaboration, and digital literacy independently, although students experience problems in video editing because they are not used to using these
Rash Model Approach for Analysis of Misconception on Chemistry Learning with Distractor Analysis
Multiple-choice questions can be used to identify misconceptions through distractor analysis. Distractor analysis for identifying misconceptions using Rasch modelling to find out how students choose options and whether they have any misconceptions. The test instrument uses questions from the teacher association in Indonesia to assess students’ ability to master chemical contexts. The number of question items used is 35 and has been validated and tested for reliability to be feasible to use. Questions were given to 462 first-year high school students. The fit item analysis results show that there are several questions related to clothing that indicate misconceptions. This is supported by the distractor analysis value, which found that misconceptions indicate questions related to electrolysis, the incidence of colligative properties in daily life and the factors that affect corrosion. The distractor’s value and the option probability curve are used to see how students know the ideas offered. The analysis results found that the material in the form of concepts and their application showed a large misconception, in which students would find it difficult to combine concepts and their applications
The bioactive of Pinus merkusii needle and bark extract as antioxidantand anti-aging
Pinus merkusii is a native pine species to Southeast Asia and has used as an oleoresins source and raw material for pulp and paper industries. This plant also possesses several biological activities, such as anti-inflammatory and larvicidal activity. This study aims to evaluate the antioxidant and antiaging activity of P. merkusii needle and bark. The qualitative phytochemical screening was used to evaluate the presence of secondary metabolites compounds. DPPH (2,2-diphenyl-1-picryl-hydrazyl) methods evaluated the antioxidant activity, and an anti-tyrosinase assay was used to evaluate the antiaging activity. Phytochemical analysis showed flavonoids, phenols, alkaloids, tannins, and terpenoids in both extracts. Bark extract showed the presence of saponins and triterpenoids, while needle extract possesses steroids. The antioxidant activity (IC50) of P. merkusii bark extract was 59.32 ± 1.74 µg/mL, stronger than needle extract (68.67 ± 1.47 µg/mL). Also, the bark extract showed higher inhibitory activity of tyrosinase (IC50) 74.97 ± 1.54 µg/mL than needle extract (96.08 ± 1.77 µg/mL). From this investigation, P. merkusii bark extracts appeared to have more potential as a natural source of antioxidants and antiaging and might be beneficial in these subjects
Nitrate Adsorption capacity of Activated Gamalama Volcanic Ash
The adsorption process of nitrate from an aqueous solution by using activated Gamalama volcanic ash was investigated. Gamalama volcanic ash (VA) was activated with HNO3 2M. The effect of adsorbent mass and initial nitrate concentration on nitrate adsorption were observed in this study. The adsorption process was conducted using a various mass of adsorbent (1 g, 2 g, 4 g, 6 g, and 8 g), various initial concentrations of nitrate (20 mg/L, 30 mg/L,40 mg/L, 50 mg/L, and 60 mg/L). The increasing of adsorbent mass decreased the adsorption capacity was observed. It was also found that the increase in initial concentration increased the adsorption capacity. The highest nitrate adsorption capacity showed by 1 gram adsorbent for 0.167 mg/g, and at nitrate initial concentration 80 mg/L, for 1.831 mg/g. Adsorption isotherm of nitrate on activated VA was determined and figured. These isotherms were modelled according to Freundlich and Langmuir adsorption isotherm
Synthesis of Na-CMC Modified Cellulose Membrane From Water Hyacinth (Eichhornia Crassipes) Rods Against Cr (VI) Metal Adsorption
Metal ion Cr (VI) is a type of heavy metal waste that is dangerous, so we need a method to reduce the level of pollution. The separation method using a cellulose membrane is an effective method to reduce the level of Cr (VI) metal pollution, by utilizing natural materials such as water hyacinth plants which are known to contain high enough cellulose. The purpose of this study was to determine the effect of concentration variations with time variations on the adsorption capacity of Cr (VI) metal ions from Na-CMC modified cellulose membranes from water hyacinth (Eichhornia crassipes) stems. This research uses experimental research methods, the steps that have been carried out are sample treatment, extraction, bleaching, hydrolysis, Na-CMC modified cellulose membranes. Data analysis was performed by sample characterization test using the FTIR Spectroscopy method and for metal content analysis using the Atomic Absorption Spectrophotometer (AAS) method. The results showed that there was an effect of concentration variations and time variations on the adsorption capacity of Cr (VI) metal ions. At the concentration variation with the largest adsorption capacity of 1.24 mg/gram occurred at a concentration of 30 mg/L and at the time variation the largest adsorption capacity of 0.917 mg/gram occurred at 30 minutes. The results respectively of FTIR showed functional groups O-H, C-H, and C-O in non-modified cellulose and there was no significant effect after the addition of Na-CMC, as evidenced by the similar FTIR spectrum without any shift or new peaks appearing.
Synthesis of Conjugated Copolymers Fluorene-based on Thieno-thiophene for Photovoltaic Cells
Organic solar cells have been receiving more attention in the recent years due to the cost bottleneck cap of inorganic solar cells and the increasing demand for more low-cost renewable power sources. In this work, poly(9,9-didodecylfluorene-alt-thieno[3,2-b]thiophene), P1 composed of alternating fluorene based co-polymer unit was successfully prepared by direct arylation polymerization. P1 composed of alternating fluorene unit as a donor unit and thieno[3,2-b]thiophene as a donor unit which is a donor-donor co-polymer. The colour and phase of P1 were observed. TLC showed positive result for P1. The surface morphology of P1 was identified by SEM. The structure of P1 was confirmed by using 1H-NMR and 13C-NMR. Functional group present of P1 were identified by using FTIR. The λmax and range of adsorption of P1 were identified and band gap were calculated. The physical characteristics of P1 was compared and discussed. Based on the chemical characteristics, P1 has a high potential as organic photovoltaic material as UV-Vis shown a better adsorption range and lower band gap.
Synthesis and Characterization Nanosilica from Rice Husk Ash Using Sol-Gel Method with Addition Of PEG-6000 and PVA
Nano-silica (NS) from rice husk ash was successfully synthesized using a sol-gel process with the addition of polyethylene glycol (PEG) 6000 and polyvinyl alcohol (PVA) as a template. The purpose of this study is to investigate the properties of NS functional groups and the effect of PEG6000 and PVA concentrations (5%, 10%, and 15% (b / v)) on the size, morphology, and distribution of nanosilica. The functional groups of NS are characterized by Fourier transform infrared (FTIR), the size and morphology of NS are characterized by scanning electron microscopy (SEM). In contrast the size analyzer characterizes the particle size distributionof particulate matter (PSA). The results indicated that the addition of PEG-6000 and PVA affected the size and morphology of NS. The FTIR spectra showed the presence of silanol (Si-OH) and siloxane (Si-O-Si) groups. According to the SEM results, the morphology of NS -PEG is round and relatively more uniform than the amorphous morphology of NS-Control and NS-PVA. Instead of PEG-6000, Sol-gel PVA can be obtained with a narrow particle size distribution