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PERBANDINGAN RERATA EKSPRESI PROTEIN Bax DAN Bak PADA PREEKLAMPSIA BERAT DAN KEHAMILAN NORMOTENSI
PERBANDINGAN RERATA EKSPRESI PROTEIN Bax DANBak PADA PREEKLAMPSIA BERAT DAN KEHAMILANNORMOTENSITejo Sujatmiko*, Diah Rumekti H*, Detty S Nurdiati*ABSTRACTBackground: Preeclampsia is still become major cause of maternal and perinatal mortality. The placentais an important and central focus on the pathogenesis of preeclampsia. Failure of trophoblast cells toperform remodeling on spiral arteries due to excessive apoptosis may cause uteroplacental ischemiaand endothelial cells damage, this induce clinical manifestations of preeclampsia especially through theintrinsic pathway. Intracellular Bax and Bak are genes that play a role as a cells apoptosis regulator (as proapoptosis).They are located in the mitochondria and endoplasmic reticulum and would in turn activatecaspase the intrinsic apoptotic pathway that cascade resulting in cell death processes.Objective: Comparing the mean of Bax and Bak protein expression between normotensive pregnancies andsevere preeclampsia.Method: This research is a cross-sectional study design. The subjects were severe preeclampsia andnormotensive patients treated at RSUP dr. Sardjito Jogjakarta between October 2011 to March 2012,with total patients of 81. Bak and Bax protein expression were measured with immunohistochemistrytechniques.Result and Discussion: The mean expression of Bax and Bak proteins in severe preeclampsia group weresignificantly higher compared to normotensive group. The mean value of Bax expression was 0,23 (CI 95% 0,12 - 0,34) and the mean expression of Bak was 0,44 (95 % CI 0,10 - 0,78).Conclusion: Expression of Bax and Bak proteins in severe preeclampsia is higher than normotensivepregnancies and Bax protein gave more effect statistically in preeclampsia compared to Bak protein.Keywords: trophoblast, immunohistochemistry, severe preeclampsia, Bak protein, Bax protein, apoptosis.ABSTRAKLatar belakang: Preeklampsia masih merupakan penyebab kematian maternal dan perinatal yang utama.Plasenta merupakan fokus sentral dan penting pada patogenesis terjadinya preeklampsia. Kegagalan seltrofoblas melakukan remodeling arteri spiralis akibat proses apoptosis yang berlebihan menyebabkanterjadinya iskemia uteroplasenter dan kerusakan sel endotel yang menimbulkan manifestasi klinispreklampsia terutama terjadi melalui jalur intrinsik intraseluler dimana Bax dan Bak adalah gen-genyang berperan sebagai regulator apoptosis pada sel (sebagai pro-apoptosis). Mereka terletak di dalammitokondria dan reticulum endoplasma dan bekerja mengaktifkan caspase cascade sehingga terjadiproses kematian sel.Tujuan: Membandingkan rerata ekspresi protein Bax dan Bak antara preeklampsia berat dengan kehamilannormotensi.Metode: Penelitian ini merupakan rancangan penelitian potong lintang dengan sampel penderitapreeklampsia berat dan normotensi yang dirawat di RSUP dr. Sardjito Jogjakarta antara bulan Oktober2011 hingga Maret 2012, sebanyak 81 pasien. Pengamatan ekspresi protein Bak dan Bax dilakukan denganteknik imunohistokimia.Hasil dan Pembahasan: Rerata ekspresi protein Bax dan Bak pada kelompok preeklampsia berat lebihtinggi secara bermakna di bandingkan kelompok normotensi Dengan nilai rerata ekpresi Bax 0.23 (CI 95%0.12 – 0.34) dan rerata ekspresi Bak 0.44 (CI 95% 0.10 – 0.78).Kesimpulan: Ekspresi protein Bax dan Bak pada preeklampsia berat lebih tinggi dibanding dengankehamilan normotensi dan protein Bax lebih berpengaruh pada preeklampsia dibanding dengan proteinBak.Kata kunci: trofoblas, imunohistokimia, preeklampsia berat, protein Bak, protein Bax, apoptosis.* Departement of obstetrics and gynecology* Medical Faculty of Gadjah Mada University* Sardjito Hospita
Does Misoprostol for Induction of Labor Increase the Risk of Uterine Rupture?
Background: Misoprostol is a synthetic prostaglandin E1 analogue which is now commonly used for induction of labor. Hyperstimulation is a complication of misoprostol that may lead to uterine rupture.Objective: To find the association between misoprostol exposure for induction of labor with uterine rupture.Methods: Case were all women who delivered in Sardjito and affiliate Hospitals from January 2007 to November 2012 with the diagnosis of uterine rupture. Controls were taken randomly from the same hospital. Chi square test and logistic regression model were used for statistical analysis.Result and Discussion: There were 53 cases of uterine rupture and 199 controls. The incidence of uterine rupture was 53 over 64,244 deliveries or 0,08%. Risk of of uterine rupture associated with misoprostol exposure was 1, 09 (CI 95% 0,52-2,2), while that of oxytocin exposure was 0,80 (CI 95% 0,35-1,85). Logistic regression analysis showed that the highest risk factor associated with uterine rupture was fetal weight > 3500 (OR 3,46; 95% CI 1,48-8,56) followed by parity (OR 2,56;95% CI 1,019-6,465) and vacuum extraction(OR 2,45;95% CI 0,94-6,39).Conclusion: There was no association between misoprostol exposure with uterine rupture. Fetal weight> 3500 gram, Parity more than 3, and vacuum extraction increased the risk of uterine rupture associated with misoprostol use.Keywords: Misoprostol, induction of labor, uterine rupture, fetal weight, parity
Perbandingan hasil stimulasi ovarium dengan kombinasi klomifen sitrat gonadotropin dan klomifen sitrat pada inseminasi intra uteri
Background: Infertile couple with the cause of unexplained infertility and male factor can follow intrauterine insemination (IUI) program as a cheap and easy method for infertility therapy. Ovarian stimulation by combination of clomiphene citrate and gonadotropin and also clomiphene citrate alone was done as a superovulation mode to get higher number of mature follicle to gain higher pregnancy rate. Objective : To compare the amount of mature follicles and endometrial thickness as an outcome of ovarian stimulation between combination drug of clomiphene citrate and gonadotrophin with clomiphene citrate alone.Methods: Observational retrospective cohort. Subject is one cycle intrauterine insemination stimulated either by combination CC gonadotrophin or CC alone, eligible in inclusion criteria and exclusion criteria. Statistic test used was independent t-test, chi-square and logistic regression.Location of study: Infertility Clinic of Permata Hati, dr. Sardjito Hospital, Yogyakarta.Result: A total of 142 cycle from 98 couples followed IUI and stimulated by combination CC gonadotrophin (n=72) or CC alone (n=70). Multiple mature follicle number was different and statistically significant 77% vs 54%, RR 1,433 (IK95% 1,118-1,836), p=0,005, while endometrial thickness > 7mm was more frequent in combination group but not statistically different with percentage 81,9% vs 74,3%, RR 1,103 (CI95% 0,926-1,315), p=0,367.Conclusion: Ovarian stimulation by combination CC gonadotropin resulting of more multiple mature follicle number while good endometrial thickness was more in combination group but not statistically significant.Keywords: ovarian stimulation, clomiphene citrate, gonadotrophin, multifollicular, endometrial thicknes
RASIO ESTRIOL/ ESTRADIOL TINGGI SEBAGAI PREDIKTOR KEBERHASILAN INDUKSI PERSALINAN PADA KEHAMILAN LEWAT WAKTU
RASIO ESTRIOL/ ESTRADIOL TINGGI SEBAGAI PREDIKTORKEBERHASILAN INDUKSI PERSALINAN PADA KEHAMILANLEWAT WAKTUMuhammad Nur Adintyo Rahman1, Shinta Prawitasari2, Heru Pradjatmo3ABSTRACTBackground: Induction of labor is a common procedure performed at 15-20 % of pregnancies. The mostcommon indication was prolonged pregnancy (70 %). The past decade labor induction rate was increased2-fold as well as the risk of cesarean section. Difficulties to predict the success of induction made predictorsof success of induction widely studied. Predictors can be physical or chemical markers. One of the chemicalmarker is the ratio of estriol to estradiol levels.Objective: To determine the value of the ratio of estriol/ estradiol to predict success of induction of laborin prolonged pregnancy.Method: The design of study are Prospective Cohort. Study two hospitals (Wonosobo District Hospitaland Banjarnegara District Hospital) used in this study from September 10, 2013 until December 31,2013. Blood sampling was drown from the subject before induction to examin the levels of estriol andestradiol the induction which end in vaginal delivery were noted as succesull induction Receiver OperatingCharacteristic (ROC) method in order to determine the sensitivity, specificity, positive predictive value,negative predictive value and Area Under the Curve. Bivariate and multivariate analyzes also used todetermine the correlation between variables.Results and Discussion: This study obtained 76 samples, 69 with successful induction and 7 failed ofinduction. The research got a cut-off was point 35 the sensitivity was 71% value, specificity value of 71%,positive predictive value 49%, negative predictive value was 55.6%. Area Under the was value of 80,7%.Positive likelihood ratio 1,06 and negative likelihood ratio 0,88. Bivariate and multivariate analysis showedthat the ratio of estriol / estradiol ≥ 35 ng / mL significantly associated with successful induction (OR 9,598;95% CI 1,378-66,859) Bishop score was also associated with a significant induction success (OR 13,481;95% CI 1,955 -92,955)Conclusion: This study shows that the proportion ratio of estriol / estradiol in succeed induction groupwere higher (≥ 35) compared with induction failure group (<35).Keywords: prolonged pregnancy, labor induction , estriol/ estradiol ratio, predictorsABSTRAKLatar Belakang: Induksi persalinan adalah prosedur umum yang dilakukan pada 15-20% kehamilan.Indikasi tersering adalah kehamilan lewat waktu (70%). Satu dekade terakhir angka induksi persalinantelah meningkat 2 kali lipat begitu juga dengan risiko seksio sesarea. Keberhasilan induksi sulit diprediksi.Prediktor keberhasilan induksi banyak diteliti baik penanda fisik maupun kimia. Salah satu penanda kimiaadalah rasio kadar estriol terhadap estradiol.Tujuan: Mengetahui nilai rasio kadar estriol estradiol untuk memprediksi keberhasilan induksi padakehamilan lewat waktuMetode: Kohort prospektif. Dua rumah sakit (RSUD Wonosobo dan RSUD Banjarnegara) dipakai dalampenelitian ini dari 10 September 2013 sampai 31 Desember 2013. Subyek yang memenuhi kriteriainklusi dan eksklusi diambil sampel darah sebanyak 5 ml sebelum Induksi untuk diperiksa kadar estrioldan estradiol kemudian dilihat keberhasilan induksinya. Analisis yang digunakan adalah metode ReceiverOperating Characteristic (ROC) untuk dapat mengetahui nilai sensitivitas, spesifitas, nilai ramal positif,nilai ramal negatif dan Area Under Curve. Analisis X2 dan Regresi logistik digunakan untuk mengetahuihubungan antar variabel.Hasil dan Pembahasan: Selama waktu penelitian didapatkan 76 sampel, 69 dengan induksi berhasil dan7 gagal induksi. Dengan cut off point 35, nilai sensitivitasnya 71%, nilai Spesifitas 71%, nilai ramal positif49%, nilai ramal negatif 55,6%. Nilai Area Under Curve sebesar 80.7%. Likelihood ratio positive 1,06 danlikelihood ratio negative 0,88. Hasil analisis multivariat menunjukkan bahwa Rasio estriol/ estradiol ≥ 35berhubungan dengan keberhasilan induksi secara signifikan (RO 9.598; IK 95% 1.378-66.859) Skor Bishopjuga berhubungan dengan keberhasilan induksi secara signifikan (RO 13,481; IK 95% 1.955-92.955)Kesimpulan: Kelompok yang berhasil diinduksi memiliki proporsi rasio estriol/ estradiol yang lebih tinggi(≥ 35) dibandingkan dengan kelompok gagal induksiKata kunci: Kehamilan lewat waktu, induksi persalinan, rasio estriol/ estradiol, prediktor1,2,3 Bagian Obstetri dan Ginekologi Fakultas Kedokteran Universitas Gadjah Mada Yogyakart
PENGARUH IBU HAMIL PEROKOK PASIF TERHADAP KEJADIAN LAHIR MATI DI KOTA AMBON
PENGARUH IBU HAMIL PEROKOK PASIF TERHADAPKEJADIAN LAHIR MATI DI KOTA AMBONMagdalena Paunno1, Ova Emillia2, Abdul Wahab3ABSTRACTBackground: Intervention in the care for pregnant women can reduce antenatal mortality until 75%.Antenatal Care (ANC) in Ambon municipality is categorized good if compared from the mean rate ofnational level, that is, Visit 1 (89%) and Visit 4 (87.76%); however, the incidence of stillbirths in Ambonis still considered high. Data about the incidence of stillbirths in three hospitals of Ambon showed thatthere were 44.2 stillbirths per 1000 live births while national data in 2003 showed that there were only9.6 stillbirths per 1000 live births. The direct cause of stillbirth is hypoxia, that is, the lack of oxygenin a pregnant woman’s body due to the exposure of cigarette smoke. In Ambon municipality, 65% ofhouseholds have 1 active smoker and almost all of the smokers (90%) smoke inside the house. This rateof course exceeds the national rate. In addition, other factors causing stillbirth are the quality of antenatalcare, age, parity, anemia and women’s educational level.Objective: To study whether passive smoking during pregnancy is a risk factor of the incidence of stillbirths.Method: This was an observational study with case-control study design. Study sites were in three hospitalsof Ambon municipality, namely Dr. M. Haulussy District Hospital, Al-Fatah Hospital, and Sumber HidupHospital. Subjects were divided into two groups which were case and control with comparison of 1:1 (69stillbirths as case and 69 live births as control) from January to December 2007. Samples were taken usingnon probability sampling which was determined with quota sample. The analysis of quantitative dataused univariable analysis, bivariable analysis with chi-square test (χ²) and stratification, and multivariableanalysis with logistic regression.Result and Discussion: There was a significant relationship between passive smoking during pregnancyand the incidence of stillbirth based on bivariable analysis with OR=3.36 (95% CI=1.20-5.41) while basedon multivariable analysis with OR=2.8 (1.01-7.94). Other risk factors that affected the incidence of stillbirthwere the quality of antenatal care with OR=3.2 (95% CI=1.39-7.52) and anemia during pregnancy withOR=2.3 (95% CI=1.20-5.41). Meanwhile, stratification analysis showed that non anemic women duringpregnancy was significantly related to stillbirths with OR=5.7 (95% CI 1.10-55.22). However, age, parity andeducation were not the risk factors of the incidence of stillbirth in Ambon.Conclusion: Passive smoking during pregnancy was a risk factor of the incidence of stillbirth in Ambonmunicipality. Other factors that caused the incidence of stillbirths were the quality of antenatal care andanemia. However, age, and parity were not the risk factors of the incidence of stillbirths in Ambon.Keywords: pregnant woman, passive smoking, stillbirthINTISARILatar belakang: Intervensi pada perawatan ibu hamil dapat menurunkan kematian perinatal hingga 75%.ANC di Kota Ambon dikategorikan baik, bila dilihat angka rata-rata secara nasional yaitu K1 89%, K4 87,76%namun, kejadian lahir mati sangat tinggi dibanding angka nasional. Salah satu penyebab langsung lahirmati adalah hypokxia yaitu kekurangan oksigen dalam tubuh ibu, akibat dari ibu hamil terpapar asaprokok. Di Kota Ambon, 65% rumah tangga mempunyai 1 orang perokok, dan hampir semua perokok (90%)merokok di rumah. Angka ini lebih tinggi dari angka nasional. Faktor lain menyebabkan lahir mati adalahkualitas antenatal care, umur, paritas anemia ibu selama hamil, pendidikan ibu yang rendah.Tujuan: Penelitian ini untuk mengetahui apakah ibu hamil perokok pasif merupakan faktor risiko kejadianlahir mati.Metode: Penelitian observasional dengan rancangan kasus-kontrol. Lokasi penelitian pada 3 RS di KotaAmbon yaitu: RSUD dr. M. Haulussy, RS. Al-Fatah, RS. Sumber Hidup. Subjek penelitian 1:1 69 lahir mati(kasus) dan 69 lahir hidup (kontrol) pada bulan Januari sampai dengan bulan Desember 2007. Pengambilansampel dengan cara non probability sampling, ditentukan secara quota sample . Analisis data terdiridari analisis univariabel, analisis bivariabel menggunakan uji chi-square (χ²), stratifikasi serta analisismultivariabel menggunakan regresi logistik.Hasil dan Pembahasan: Ada hubungan yang bermakna antara ibu hamil perokok pasif dengan kejadianlahir mati. Analisis bivariabel OR=3,36 (95% CI=1,20-5,41) analisis multivariabel OR=2,8 (1,01-7,94). Faktorrisiko lain yang mempengaruhi kejadian lahir mati adalah: Kualitas antenatal care mempunyai nilai OR=3,2(95% CI=1,39-7,52), ibu hamil anemia OR=2,3 (95% CI=1,20-5,41) dan pendidikan OR=2,42 ( 1,15-5,10).Saat analisis strativikasi, ibu tidak anemia mempunyai hubungan bermakna dengan lahir mati OR=5,7 (95%CI 1,10-55,22). Umur, paritas dan pendidikan bukan merupakan faktor risiko lahir mati di Kota Ambon.Kesimpulan : Ibu hamil perokok pasif merupakan faktor risiko terhadap kejadian lahir mati di Kota Ambon.Faktor lain yang menyebabkan lahir mati adalah kualitas antenatal care dan anemia ibu hamil.Kata kunci: ibu hamil, perokok pasif, lahir mati.1 Air Selobar Community Health Center, Ambon Health Office, Maluku Province2 Obstetric and Gynecology Division, Faculty of Medicine,Gadjah Mada University, Yogyakarta3 Maternal and Child Health-Reproductive Health, Graduate Program,Faculty of Medicine, Gadjah Mada University, Yogyakart
HUBUNGAN ANTARA STRESOR PSIKOSOSIAL DENGAN GANGGUAN MENSTRUASI PADA REMAJA SMP PASCA ERUPSI MERAPI DI KECAMATAN CANGKRINGAN KABUPATEN SLEMAN YOGYAKARTA
HUBUNGAN ANTARA STRESOR PSIKOSOSIAL DENGAN GANGGUAN MENSTRUASI PADA REMAJA SMP PASCA ERUPSI MERAPI DI KECAMATAN CANGKRINGAN KABUPATEN SLEMAN YOGYAKARTAAnik Dwi Marga 1, Sumarni DW 2, Djaswadi Dasuki 3ABSTRACTBackground: Merapi eruption can cause tremendous damage, not only physically but also mentallywhich will trigger the emergence of mental disorders in adolescence and even into adulthood. After theeruption of Merapi, adolescents and their families should move from shelters to permanent residence.Resettlement to permanent residence had resulted in a new variety of stressors. The new stressors wouldaffect the release of LH (luteinizing hormone) and FSH (follicle-stimulating hormone) which may affectthe occurrence of menstrual disorders. Menstrual disorder might interfere with learning achievement inadolescence.Objective: To determine the relationship between psychosocial stressors with menstrual disorders infemale junior high school students after the eruption of Merapi in Cangkringan Sleman YogyakartaMethod: This study is a observational with cross-sectional design and combined with a qualitativeapproach. Respondents in this research is class VII students who were menstruating in CangkringanSleman. Samplings method used was total sampling. The research instrument was a questionnairepsychosocial stressors (IPSP), menstrual disorder questionnaire (SPAF) and the behavioral aspects of thequestionnaire. Datas were analysed using Chi-Square test by looking at the value of prevalence ratio andlogistic regression at the significance level of p <0.05 with a confidence interval (CI) of 95%.Result and Discussion: There was a significant correlation between psychosocial stressors and menstrualdisorders (OR; 6.47; CI = 1.436 to 29.165)Conclusion: Adolescents who experienced severe psychosocial stressors six times more likely to experiencemenstrual disorders compared to adolescents who experience mild psychosocial stressorsKeywords: Psychosocial Stressors, menstrual disorders, post-eruption of Merapi, Youth,SMP.ABSTRAKLatar Belakang: Erupsi Merapi dapat menyebabkan kerusakan yang luar biasa, tidak hanya fisik tetapijuga mental yang akan memicu munculnya gangguan jiwa pada remaja bahkan sampai masa dewasa.Pasca erupsi Merapi, remaja dan keluarganya harus pindah dari huntara ke huntap. Perpindahan tempattinggal ke huntap inilah yang mengakibatkan berbagai stresor-stresor baru.. Stresor baru tersebut akanmempengaruhi pelepasan LH (Luteinizing Hormone) dan FSH (follicle-stimulating hormone) yang dapatmempengaruhi terjadinya gangguan menstruasi. Masalah menstruasi jika tidak mendapatkan penangananyang benar dapat mengganggu prestasi belajar remaja.Tujuan: Untuk mengetahui hubungan antara stresor psikososial dengan gangguan menstruasi pada remajaSMP pasca erupsi Merapi di Kecamatan Cangkringan Kabupaten Sleman YogyakartaMetode: Penelitian ini merupakan jenis penelitian non eksperimen dengan metode observasional denganrancangan cross-sectional yang dilengkapi dengan pendekatan kualitatif. Responden dalam penelitianini adalah Siswi kelas VII SMP yang sudah menstruasi di Kecamatan Cangkringan Kabupaten Sleman.Pengambilan sampel penelitian dengan total sampling. Instrumen penelitiannya adalah kuesioner stresorpsikososial (IPSP), kuesioner gangguan menstruasi (SPAF) dan kuesioner aspek perilaku. Analisis datamenggunakan Uji Chi-Square dengan melihat nilai RP (Rasio Prevalensi) dan regresi logistik pada tingkatkemaknaan p<0,05 dengan Confidence interval 95%.Hasil dan Pembahasan: Remaja yang mengalami stresor psikososial berat beresiko 6,47 kali lebih besaruntuk terjadi gangguan menstruasi (CI 95% 1,436-29,165)Kesimpulan: Remaja yang mengalami stresor psikososial berat mempunyai resiko 6 kali lebih besarmengalami gangguan menstruasi dibandingkan dengan remaja yang mengalami stresor psikososial ringanKata Kunci: Stresor psikososial, Gangguan menstruasi, Pasca Erupsi Merapi, Remaja, SMP.1 Anik Dwi Marga dari Magister Ilmu Kesehatan Masyarakat, Fakultas Kedokteran, UGM2 Sumarni DW dari Bagian Kedokteran Jiwa Fakultas Kedokteran, UGM3 Djaswadi Dasuki Bagian Obstetri Ginekologi, Fakultas Kedokteran, UG
Pengaruh Pendidikan Kesehatan dengan Media Audiovisual Manajemen Laktasi terhadap Tingkat Pengetahuan dan Self Efficacy Ibu Menyusui
Background: Infant mortality rate in Indonesia in 2012 is 32 per 1,000 live births. It is less pleasant ifcompared to the target Ministry of Health of Republic of Indonesia tries to achieve, which is 24 by 2014. The low rate of breastfeedingto one of the dominant factor that cause the mortality it is influenced by several factors, in which one of them is the mother’sknowledge about breast milk and breastfeeding. Health education on lactation management may help increase mothers’ ability to gain information as well as their confidence to breastfeeding their baby.Objective: This research is conducted with the purpose to know the effect of health education with audiovisual on lactation management to the level of knowledge and self-efficacy among breastfeeding mothers.Method: This research is categorized as quasi experimental one, whose design applies pre-test and post-test non-equivalent control group. It is conducted toward 32 breastfeeding mothers who receive health education as the treatment group, and to 32 breastfeeding mothers who are asked to read modules about breastfeeding as the control group. The sampling technique applies purposive sampling and simple random sampling. Data are processed by computer programs using Mann-Whitney test, Wilcoxon test, and linear regression model.Result and Discussion : The score for the value of knowledge before treatment among both groups were relatively similar (p>0.05). After treatment, both groups have improvement, (p0.05). compared to control group, the intervention group has significantly higher score of knowledge (p>0.05)Conclusion: Health education by audiovisual media and modules are more effective to improve the knowledge and self-efficacy among breastfeeding mothers compared to by only modules.Keywords: Health education, Audiovisual, Modules, Knowledge, Breastfeeding, Self-Efficac
Hubungan Komunikasi Interpersonal Orang Tua dengan Perilaku Seksual Pranikah Remaja di Kota Padang
Background: The phenomenon that is troubling many parties at the present time is the pattern of the adolescent courtship leading to sexual intercourse. Most teens consider premarital sexual behavior is normal and common. Interpersonal communication parents is not good to their children will cause conflicts that impact on adolescent premarital sexual behavior. By looking at the picture of interpersonal communication old man is expected to overcome adolescent premarital sexual behavior.Objektive : The purpose of this study was to determine the relationship between interpersonal communication of parents toward adolescent premarital sexual behavior.Method: This was an observational study using cross-sectional design and mixed methods approaches (quantitative and qualitative). The experiment was conducted at SMAN A, SMAN B, SMA C Idan MAN D Padang with research subjects totaling 299 teenagers. Informants for qualitative data that consists of 4 boys, 4 girls and 8 parents of the school to be studied.Results and Discussion: Indicates that there is a statistically significant relationship (p <0.05) between the independent variables (interpersonal communication of parents) with dependent variable (adolescent premarital sexual behavior) with a RP 3.71 95% CI (2.62 to 5.25). interpersonal communication of parents after the controlled variable peers, the media and religiosity there is also an increase of 49%.Conclusion: premarital sexual behavior in adolescents at risk because interpersonal communication of parents are not good . Other factors that affect the risk of premarital sexual behavior in adolescents are peers, the media and the level of religiosity. The results of in-depth interviews permissiveness and emotionally intimate relationship with parents also have an impact on the relationship is not good between parents and teenagers in interpersonal communication.Keywords: interpersonal communication of parents, adolescent premarital sexual behavio
Hubungan antara Kepercayaan dan Keterpaparan Informasi dengan Pengetahuan dan Sikap terhadap Perawatan Metode Kanguru pada Bidan di Kabupaten Musi Rawas Sumatera Selatan Tahun 2016
Background: Infant and Neonatal mortality in Musi Rawas District is the highest in Southern Sumatera in 2014. Implementation of kangaroo mother care as Low Birth Weight treatment is still limited in the provincial general hospital Dr. Mohammad Hoesin, Palembang. At the present time, midwives as maternal and child health service provider, can access many information including Kangaroo Mother Care from various media.Objectives: This study aimed to analyze the relationship between belief in the myth of LBW care and exposure information with the knowledge and attitudes toward kangaroo mother care on midwives in Musi Rawas District of Southern Sumatra 2016.Method: Cross sectional study design used on 197 midwives with purposive sampling.Result and Discussion: The results showed that midwives who have relatifely good knowledge about KMC As much as 50,8% and having relatively positive attitude towards KMC as much as 40.1%. There are a significant relationship between belief of LBW care (ρ=0,001; OR: 3,1; 95% CI: 1,6 – 5,8), exposure information from scientific media (ρ=0,039; OR: 2,4; 95% CI: 1,0 – 5,4), training (ρ=0,001; OR: 3.5; 95% CI: 1.7 – 7,5) with knowledge about KMC on midwives.Conclusion: A significant relationship also demonstrated between exposure information from training with attitude towards KMC on midwives (ρ=0,003; OR: 2,8; 95% CI: 1,4 – 5,6). Improving quality of the midwives in Kangaroo Mother Care is very important so midwives can provide counseling, information, and education to mother since detected with LBW.Keywords: Kangaroo Mother Care, Midwife, Belief, Attitude, Knowledge of KM
Analisis Angka Seksio Caesarea di RSUP Dr. Sardjito Yogyakarta Tahun 2009-2013
Background: Caesarean section is a procedure to reduce maternal and perinatal mortality and morbidity. The caesarean section rate is continuously uprising in the last 3 decades. However, the increasing rate, especially in low risk women, may compromise maternal and perinatal outcome. In 1985, WHO recommended that optimal national caesarean rates should be in the range of 5% to 10% and the rate above 15% might be less benefits. Previous study conducted in DR Sardjito hospital reported caesarean section rate in 1996 was 13.38%, while in 2001 was 18.39%. In national level, based on Indonesia Basic Health Survey 2010, caesarean section rate was 10.8%. Therefore, in this study we analyzed the rate of Caesarean section performed in DR Sardjito hospital, and studied whether the operations occurred in high-risk group or low-risk group.Objective: To compare the rate of caesarean section between high-risk group and low-risk group in DR Sardjito hospitalMethod: Retrospective cohortResult and Discussion: Participants of this study were 7821 patients undergoing labor at RSUP DR Sardjito in 2009-2013. Among them, 3152 patients underwent caesarean section and 4669 patients underwent vaginal delivery. There was an increasing in the overall caesarean section rate of 38,7% in 2009 to 43% in 2013. T-test found the presence of significant differences between the caesarean section rate of high-risk group and low-risk group in 2009-2013 (p<0.05) with a mean difference was 28.5 (20.2-36.8). Caesarean section rate of high-risk group was significantly higher than the low-risk group (p<0.05).Conclusion: There was a difference in caesarean section rate of high-risk group compared to low-risk group. Caesarean section rate in high-risk group was significantly higher than in the low-risk group.Keywords: caesarean section rate, caesarean section, low-risk group, high- risk grou