50716 research outputs found
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Reducing the Risk of Pre-Eclampsia in Women with Polycystic Ovary Syndrome Using a Combination of Pregnancy Screening, Lifestyle, and Medical Management Strategies
Get PDFPolycystic ovary syndrome (PCOS) is a multisystem disorder that presents with a variety of phenotypes involving metabolic, endocrine, reproductive, and psychological symptoms and signs. Women with PCOS are at increased risk of pregnancy complications including implantation failure, miscarriage, gestational diabetes, fetal growth restriction, preterm labor, and pre-eclampsia (PE). This may be attributed to the presence of specific susceptibility features associated with PCOS before and during pregnancy, such as chronic systemic inflammation, insulin resistance (IR), and hyperandrogenism, all of which have been associated with an increased risk of pregnancy complications. Many of the features of PCOS are reversible following lifestyle interventions such as diet and exercise, and pregnant women following a healthy lifestyle have been found to have a lower risk of complications, including PE. This narrative synthesis summarizes the evidence investigating the risk of PE and the role of nutritional factors in women with PCOS. The findings suggest that the beneficial aspects of lifestyle management of PCOS, as recommended in the evidence-based international guidelines, extend to improved pregnancy outcomes. Identifying high-risk women with PCOS will allow targeted interventions, early-pregnancy screening, and increased surveillance for PE. Women with PCOS should be included in risk assessment algorithms for PE.</p
Comparison of Laboratory and Non-Laboratory-Based 2019 World Health Organization Cardiovascular Risk Charts in the Bhutanese Population
No full textThe World Health Organization (WHO) recommends the use of color-coded cardiovascular disease (CVD) risk charts for CVD management. This study evaluated the agreement between the laboratory and non-laboratory 10-year CVD risks based on 2019 WHO CVD risk-prediction charts. The agreement of CVD risk scores among 40- to 69-year-old Bhutanese population stratified by gender and age groups (<60 and ≥60 years) was determined via weighted kappa statistics. In the general population, there was substantial agreement between the two CVD risk score charts for all ages and <60 years but a moderate agreement for participants aged ≥60 years. In males, substantial agreement was observed in all ages and in <60 years and moderate agreement in ≥60 years. In females, both the predictions showed substantial agreement in all ages and <60, but a moderate agreement for ≥60 years. The non-laboratory-based risk charts can be used interchangeably with laboratory-based charts for predicting 10-year CVD risk in resource-constrained countries like Bhutan.</p
Incorporating Complexity and System Dynamics into Economic Modelling for Mental Health Policy and Planning
Get PDFCare as usual has failed to stem the tide of mental health challenges in children and young people. Transformed models of care and prevention are required, including targeting the social determinants of mental health. Robust economic evidence is crucial to guide investment towards prioritised interventions that are effective and cost-effective to optimise health outcomes and ensure value for money. Mental healthcare and prevention exhibit the characteristics of complex dynamic systems, yet dynamic simulation modelling has to date only rarely been used to conduct economic evaluation in this area. This article proposes an integrated decision-making and planning framework for mental health that includes system dynamics modelling, cost-effectiveness analysis, and participatory model-building methods, in a circular process that is constantly reviewed and updated in a ‘living model’ ecosystem. We describe a case study of this approach for mental health system policy and planning that synergises the unique attributes of a system dynamics approach within the context of economic evaluation. This kind of approach can help decision makers make the most of precious, limited resources in healthcare. The application of modelling to organise and enable better responses to the youth mental health crisis offers positive benefits for individuals and their families, as well as for taxpayers.</p
An Exploratory Review on Lithium-Ion Battery Fire Risk Mitigation Using Deep Learning Approaches
Get PDFLithium-ion batteries (LIBs) have been extensively adopted in various applications ranging from portable electronics to electric vehicles owing to their high energy density and efficiency. Meanwhile, LIB fire risks have also increased with many incidents causing life and property losses. With the advancement of machine learning techniques, deep learning approaches have been used in research on battery fire safety, particularly in battery safety risk prediction, risk classification, thermal runaway detection, and system optimization. This review summarizes deep learning approaches applied to mitigating LIB fire risk. As the LIB industry expands and safety regulations are relatively new, significant opportunities for improvement and unexplored technology areas remain. These include thermally stable components, smart material design, battery thermal management systems for safety monitoring, safety design models for battery systems, thermal management systems, battery safety evaluation systems and more. Deep learning can effectively and flexibly align with these developments. We compare and discuss state-of-the-art studies that implement deep learning in battery thermal performance and risk mitigation, especially using images for early battery fire detection. We also propose further prospects for developing new energy materials and advancing battery technology. By applying deep learning approaches, researchers can integrate multiple strategies and develop lithium-ion batteries or battery thermal management systems with enhancedsafety performance
From online trolls to ‘Slut Shaming’:understanding the role of incivility and gender abuse in local government
No full textFair political representation is an important goal of democratic governments, yet Australia lags behind many democracies in women’s representation in elected politics. Attacks against women in public spaces through harassment and verbal abuse have long constrained women’s ease in physical spaces and, in the digital age, this has extended into online spheres. This paper examines the impact of on- and offline incivility on women’s experiences in local politics. It focuses on Australia’s southern state of Victoria and its 79 local government municipalities. We conduct two surveys of men and women elected representatives (N1 = 222, N2 = 205) to determine their experiences during the campaigning period and first year on council. We follow up with in-depth interviews with women who have experienced gender harassment (n = 10) to further understand its impacts. We offer new insights in to a ‘push factor’ that contribute to women leaving elected local government and their political underrepresentation.</p
Associations Between Supported Accommodation and Health and Re-offending Outcomes:A Retrospective Data Linkage Study
Get PDFFollowing release from prison, housing and health issues form a complex and mutually reinforcing dynamic, increasing reincarceration risk. Supported accommodation aims to mitigate these post-release challenges. We describe the impact of attending Rainbow Lodge (RL), a post-release supported accommodation service for men in Sydney, Australia, on criminal justice and emergency health outcomes. Our retrospective cohort study using linked administrative data includes 415 individuals referred to RL between January 2015 and October 2020. Outcomes of interest were rates of criminal charges, emergency department (ED) presentations and ambulance attendance; and time to first reincarceration, criminal charge, ED presentation and ambulance attendance. The exposure of interest was attending RL; covariates included demographic characteristics, release year and prior criminal justice and emergency health contact. Those who attended RL (n = 170, 41%) more commonly identified as Aboriginal or Torres Strait Islander (52% vs 41%; p = 0.025). There was strong evidence that attending RL reduced the incidence criminal charges (adjusted rate ratio [ARR] = 0.56; 95% confidence interval [CI] 0.340.86; p = 0.009). Absolute rates indicate a weak protective effect of RL attendance on ED presentation and ambulance attendance; however, adjusted analyses indicated no evidence of an association between attending RL and rates of ED presentations (ARR = 0.88; 95% CI = 0.65–1.21), or ambulance attendance (ARR = 0.82; 95% CI = 0.57–1.18). There was no evidence of an association between attending RL and time to first reincarceration, charge, ED presentation or ambulance attendance. Greater detail about reasons for emergency health service contact and other self-report outcome measures may better inform how supported accommodation is meeting its intended aims.</p
Community sport, Australian sport policy, and advocacy: The views of community sport club officials
No full textIn Australia, the policy priorities and processes of government and national governing bodies of sport impact how community sport organizations operate. This study explored the views of community sport club (CSC) officials (n = 53) in the Illawarra region in New South Wales, where there is a disparity in impact compared with their better-resourced urban counterparts concerning sustainability, policy, and advocacy matters. Participants were surveyed for their views about the typically top-down policy processes, inter-organizational relationships, and advocacy for community sport. CSC officials participated in an online survey to assess opinions on resource issues and policy processes. The findings demonstrated that community sport is challenging to sustain and that CSC officials have little influence on policy. The outcome points to an appetite for advocacy from CSC officials in policy creation. Further, the Advocacy Coalition Framework is proffered as a platform for evaluating the viability of advocacy within community sport.</p
