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Evaluation of Business Performance Through Financial Analysis Tools
No full textThis bachelor thesis deals with a comprehensive financial analysis of the company Kostelecké uzeniny a.s. for the period from 2019 to 2023. It is divided into four parts: in the first part, it discusses the objective of the work, the procedure and the methodology. In the second - theoretical part, it defines the basic concepts, methodological procedures and tools of financial analysis. The third - practical part contains the actual analysis of the company's financial statements, including horizontal and vertical analysis, ratio and gap analysis and evaluation of aggregate bankruptcy and creditworthiness models. Based on the information found, the fourth part then formulates specific proposals, the implementation of which could contribute to improving the financial situation of the company
Multimodal Transport Planner for the South Moravian Region
No full textThe main goal of this thesis is to implement a multimodal planner in form of a web application that combines car and public transport by using transfer points where the transition from car to public transport happens. This application is particularly suitable for daily commuters who want to combine the speed and flexibility of a car with comfort and ecofriendliness of public transport or they live in a place with poor public transport connections.The application was implemented by React library and Deno runtime and was tested by real users
Proposal for Changes to the Marketing Mix
No full textThe bachelor’s thesis deals with the marketing mix of entrepreneur XY, who focuses on the automotive business. He specializes in selling, servicing and purchasing various car types and brands. The theoretical part is based on professional literature of marketing analyses. These analyses are further applied in the next, analytical part, in which the current state of the entrepreneur XY was determined. Conclusion is in the proposal part, in which are presented proposals for improving the marketing mix
Library for efficient representation and manipulation of software performance data
No full textTáto diplomová práca predstavuje implementáciu novej knižnice navrhnutej na efektívnu reprezentáciu a manipuláciu s dátami o výkone softvéru. Knižnica, motivovaná rastúcou komplexnosťou softvéru a potrebou efektívnej analýzy výkonu, rieši výzvy spojené s rôznorodosťou formátov výkonnostných dát a s obmedzeniami existujúcich nástrojov. Jadrom knižnice je schopnosť vytvárať rôzne dátové štruktúry, ako napríklad Strom kontextov volaní (Calling Context Tree) a Graf volaní (Call Graph), z dát zozbieraných počas vykonávania programu. Modulárna architektúra umožňuje používateľom rozšíriť sadu podporovaných vstupných formátov, definovať dáta uložené v štruktúrach, alebo prispôsobiť proces vytvárania dátovej štruktúry. Pre dátové štruktúry je k dispozícii rad operácií, vrátane rôznych metód prechádzania, rozdielovej analýzy na identifikáciu zmien medzi verziami zozbieraných dát, a orezávania na zníženie veľkosti dátovej štruktúry. Podporovaná je aj serializácia a kompresia dátových štruktúr. Experimentálne vyhodnotenie demonštruje výkonnosť a pamäťovú efektivitu knižnice, pričom zdôrazňuje jej potenciál významne zlepšiť spracovanie dát a vytváranie profilov v projekte Perun. Budúca práca sa bude zameriavať na integráciu knižnice do projektu Perun, a na ďalšie rozšírenie a optimalizáciu jej hlavnej funkcionality, napr. podporovaných vstupných formátov a dátových štruktúr
Zeolite-amine complex catalysis of Meerwein-Ponndorf-Verley type hydrogen transfer reactions
No full textMeerwein-Ponndorf-Verley (MPV) reduction is a selective hydrogen transfer reaction that converts carbonyl compounds to the corresponding alcohols under mild conditions, offering a safer alternative to conventional hydrogenation by avoiding the use of molecular hydrogen. Recently, Lewis acid zeolites, particularly Zr- and Sn-substituted beta zeolites, have been identified as effective catalysts. Although MPV reduction is typically highly selective, its selectivity can decrease when the substrate structure allows competing Lewis catalysed reactions. In such cases, the addition of organic bases can increase selectivity by forming zeolite-amine complexes, although the mechanism as well as the base structure-activity correlations are unknown. This study focuses on the MPV reduction of citronellal, a bio-derived aldehyde, in the presence of Zr- and Sn-beta catalysts, which suffers from side reactions like carbonyl-ene cyclization and acetalization. Small nitrogen-containing organic bases such as pyridine and N- methylpiperidine were used to increase the citronellol selectivity and to disclose the structure- activity correlations between the base and the selectivity improvement. A series of pyridine- derived bases shifted selectivity in favour of citronellol except 2,6-ditert-butylpyridine, which is..
Prevalence of smoking during pregnancy and its effects on baby's birth weight
No full textThis thesis focused on the prevalence of smoking during pregnancy and its impact on newborn birth weight. The topic was chosen due to its relevance and the significant health consequences associated with smoking during pregnancy. The aim of the study was to assess the prevalence of smoking in pregnancy, to characterize pregnant smokers, and to determine whether and how smoking affects birth weight. In addition, the study sought to identify other demographic and socioeconomic factors influencing this relationship. The analysis was based on questionnaire data from the Children's Health study conducted by the National Institute of Public Health between 2001 and 2016. Statistical data analysis methods were applied, including descriptive statistics, independent samples t-tests, analysis of variance, and binary logistic regression. The results showed that the prevalence of smoking during pregnancy in the Czech Republic decreased over the observed period 1984-2011. However, it remained higher among women with lower education levels and in younger age groups. Statistically significant differences in mean birth weight were found across different birth periods, with a gradual decline in birth weight observed from 1995-1999 to 2005-2011. Significant differences were also found between maternal age groups,..
Evaluation of Teaching Methods in Biology Education and Their Impact on Career Choices Among Upper Secondary Students
No full text6 Abstract Career choice is crucial at the end of upper secondary education. Research shows that the career choice is influenced by several factors. One of these factors is how students evaluate teaching methods in individual subjects. Several authors have studie the relationship between students' evaluation of upper secondary school teaching in STEM subjects and the choice of STEM-oriendted proffesions. However, the connection between the choice of profession and students'evaluation of various teaching methods has yet not been studied in more detail. This problemtics will be discussed further in this thesis. This diploma thesis has three aims. The first aim is to compare the evaluation of teaching methods in biology teaching by third-year upper secondary school students. The second aim is to compare the interest of third-year upper secondary school students in science-oriented careers, e.g. healthcare professions, scientific professions, biology teachers, veterinarians, or farmers. The final aim is to create a mathematical model for evaluating the impact of students' evaluation of teaching methods on career choice. The literature review summarizes current knowledge about the influence of teaching methods on learning, the popularity of biological topics, the impact of teaching methods, the evaluation of..
Environmental factors influencing the entry of diaspores into habitats during secondary succession of vegetation
No full textThe entry of species into a site during secondary succession is a complex phenomenon. It is influenced by a number of environmental factors. The characteristic features of the given species, such as the way its seeds spread and the distance over which they can be dispersed, play an important role. However, the entry of species is also influenced by other environmental factors. These can be divided into biotic and abiotic, depending on what is responsible for the given factors. The time sequence in which a given species reaches a given site and is able to settle and grow also plays an important role. In addition to natural factors, humans also influence the entry of species, either directly or indirectly. This work focuses mainly on abandoned fields, which are a good example of the succession stage and can be used to observe how different plant species appear over time. Due to historical reasons there are many such fields in the Czech Republic. In general, it can be said that each factor plays a key role in the entry of a species into a location. The properties of a given species themselves are very important - at what stage of succession the species is able to manifest itself, what type of seed transmission occurs in it, whether a given type of transmission allows transmission over longer distances..
Application of Voltammetry and Amperometry in the Determination of Warfarin
No full text5 Abstract This thesis deals with the study of the electrochemical behaviour of the anticoagulant drug warfarin (WAR). A screen-printed carbon electrode (SPCE) and an ultra-trace graphite electrode (UTGE) were used as working electrodes. The techniques of batch injection analysis with amperometric detection (BIA-AD), differential pulse voltammetry (DPV) and DC voltammetry (DCV) were used for the determination of warfarin. Measurements were performed in a Britton-Robinson (BR) buffer. For all used techniques, the pH dependence was measured, and the repeatability of the method was verified. For the BIA-AD technique, the optimal detection potential and parameters related to sample dosing, namely sample volume and sample dosing rate, were further searched. Using optimal conditions, the concentration dependence was measured, and the limits of detection and quantification were calculated. The developed voltammetric and amperometric methods were used for determination of the active ingredient in the tablets. The obtained values were compared with the UV-VIS spectrophotometric method, which was chosen as the reference method. Cyclic voltammetry (CV) was used to study the mechanism of electrochemical oxidation of WAR. Measurements were performed for both used working electrodes in BR buffer at pH corresponding to..
Genetic aspects of osteogenesis imperfecta
No full textThis bachelor thesis is a literature review of scientific articles dealing with the hereditary disease Osteogenesis imperfecta (also known as the brittle-bone disease) focusing on genetic aspects of this condition. It is a disease associated with type I collagen that causes patients to experience frequent fractures from birth, low bone density, growth deficiency, as well as various hearing, dental and in some cases respiratory and vascular problems. In recent years, numerous mutations in genes associated with OI fenotype have been discovered and research in this area continues. These include genes that directly code for chains of the type I collagen (COL1A1 and COL1A2) or genes whose products influence the proper post-translational modification, folding, transport or secretion of type I collagen or even bone mineralization and osteoblast differentiation. Currently, 23 types of OI are known, each with a different molecular and genetic cause or a different fenotypic manifestation. The thesis also mentiones diagnostic methods used in clinical practice and ways to manage the symptoms of patients with OI, as there is currently no causal treatment available. Key words: osteogenesis imperfecta, type I collagen, mutation, fractures, bone matrix, osteoblast