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    Baroque humanist-pracher Emmanuel Ernst von Waldstein at the Metropolitan Chapter of St. Vitus in Prague

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    Tomáš BÁRTA PRAŽÁK, Baroque humanist-preacher Emmanuel Ernst von Waldstein at the Metropolitan Chapter of St. Vitus in Prague, Praha 2023. Abstract The disserta�on presents the personality of Emmanuel Ernst von Waldstein through his own work in one of the stages of his life before he became bishop in Litoměřice. The actual content is divided into two main sec�ons: 1. Introductory study on the personality of Emmanuel Ernst von Waldstein, and 2. Edi�on of manuscript sermons. In the first part, Waldstein is presented in a broader context in the form of a biography, highligh�ng the significance of his extensive writen estate, which is also presented here; what is not neglected, of course, is Waldstein's preaching ac�vity including the interpreta�on of selected texts. Some data within Waldstein's biography have been revised, for example, informa�on about his birth and leisure ac�vi�es. Among other things, informa�on on some sources has been clarified. As far as Waldstein's sermons themselves are concerned, it is obvious that he reflected contemporary prac�ce in them, using the current knowledge and relevant facts of the cited authori�es. For the second part of the disserta�on, the primary source was a set of sermon concepts of 1746-1755 writen by Emmanuel Ernst von Waldstein, which were mostly writen in Czech (only..

    Memory Activation in Neural Networks of the Brain

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    The processes of association and separation of individual mental representations are essential for normal cognitive functions. They are vital for both non- declarative and declarative memory, especially for semantic memory, episodic memory, symbolic language, imagination and spatial orientation. Distruptions in these phenomena can have profound consequences leading to pathological conditions such as dementia or psychosis. Hippocampus, being the centerpoint of the declarative memory system, offers a valuable window for studying the formation, reactivation and modification of memory traces. Insight into mechanisms of hippocampal spatial coding provides a uniquely transparent view on neural representations, whose dynamical nature is central to processes of thought and cognition in general. Evolutionary preservation of the hippocampus and medial temporal lobe memory system enables us to study building blocks of complex phenomena, such as episodic memory, in simpler animal models. My thesis focuses on the dynamics of awake reactivation of hippocampal place cell population patterns from different environmental contexts. This ability is supposedly a key prerequisite for declarative, conscious recollection we can observe in humans. We discovered that rat models are capable of reactivating neuronal codes..

    Studies applied to bioscience research using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS)

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    Felipe Martínez Ramírez - Ph.D. Thesis abstract in Czech: "Studie aplikované na biologický výzkum za užití kapalinové chromatografie v tandemu s hmotnostní spektrometrií (LC-MS/MS)" Tato práce se zaměřuje na aplikaci kapalinové chromatografie ve spojení s tandemovou hmotnostní spektrometrií (LC-MS/MS) v biologickým výzkumu. Primárním cílem bylo vyvinout a ověřit robustní metody založené na LC-MS/MS pro posouzení klíčových analytických problémů v oblastech jako jsou lipidomika, farmakokinetika a environmentální zdraví. Studium bioaktivních lipidů bylo zaměřeno na estery mastných kyselin a hydroxymastných kyselin (FAHFA) v jedlých houbách. Necílené a cílené metody LC-MS/MS umožnily identifikaci jedinečných lipidových profilů, což podpořilo jejich použití jako chemotaxonomických markerů. Tento duální přístup poskytl detailní strukturální pohled a usnadnil druhovou diferenciaci. Ve studii metabolismu léčiv bylo LC-MS/MS spojeno s jaterním systémem Organ-on-a-Chip (OoC) pro hodnocení metabolismu tolbutamidu a jeho metabolitu, 4-hydroxytolbutamidu. Systém automatizované filtrace a zpětného proplachu filtru (AFFL) byl vyvinut pro zlepšení manipulace se vzorky a minimalizaci efektů matrice. Metoda validovaná FDA prokázala linearitu, selektivitu, vysokou preciznost, přesnost a reprodukovatelnost, a nabízí tak..

    Conducting polymers-based films for energy conversion and storage

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    Conducting polymers-based films for energy conversion and storage ABSTRACT Polypyrrole (PPy) is one of the most promising conducting polymers owing to its excellent conductivity, redox properties, and stability. The aim to develop PPy nanostructures is to significantly improve PPy's conductivity and electroactivity relevant for high performance supercapacitors. Recently, the addition of organic dyes to the polymerization of pyrrole has noticeable influence on the morphology, conductivity, and electrochemical stability of PPy. The presence of organic dyes during the chemical and electrochemical polymerization of PPy has the ability to modify the typical globular morphology of PPy to nanotubes or nanofibers with enhanced conductivity. In this study, the electrochemical properties of chemically and electrochemically prepared PPy in the presence of Safranin-O, Acid Blue 25, Acid Blue 129 and methyl orange were investigated. Specifically, electroactivity, capacitance, stability, and morphology of the obtained films were elucidated through various characterization techniques (i.e. cyclic voltammetry, galvanostatic charge-discharge, electrochemical impedance spectroscopy, and scanning electron microscopy). Results showed that the presence of organic dyes during the electrochemical polymerization of PPy has shown a..

    Public Health Communication in Obesity Prevention: Insights into the Current Media Space, Influencer Communication and Audience Preception

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    The dissertation focuses on the issue of public health communication in the field of obesity prevention, with an emphasis on the role of media and influencers in shaping the perception of this topic among target audiences. In the context of the growing prevalence of obesity in the Czech Republic, which affects more than 60% of the population, the work analyses how messages related to obesity and healthy lifestyles are presented in the media space and how these messages are perceived by the public. In its analytical part, the dissertation examines how media representation of obesity in Czech media has changed over the past two decades and the influence of digital media, especially social networks and influencers, on perceptions of a healthy lifestyle and body image. Theories of social comparison and objectification play a key role, applied to analyse how women with a BMI over 25 are influenced by media content and what consequences this has on their self-esteem and behaviour. The discussion section explores the connection between current theoretical concepts and empirical data obtained from in-depth interviews and content analysis of media content on social networks. The conclusions indicate that media messages, especially from influencers, play a significant role in shaping attitudes towards..

    Kateřina Jeřábková’s Fiction Library as Publishing Company

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    Recent works on the Bibliotéka českých původních románů historických i novověkých (Library of Czech original historical and modern novels) by the Prague printer and publisher Kateřina Jeřábková – including one work by Zuzana Urválková – tend to characterize it as a key literary project of the 1850s that, in its time, provoked an extraordinary critical response. Much remains to be clarified, however, about the circumstances under which the library, in the context of the contemporary book market, was established, promoted, operated, and eventually went defunct at the turn of 1860 and 1861. The present study addresses this issue by examining a number of printed reports, advertisements, publishers’ statements, and similar materials. With some exceptions, documentation from the publisher’s estate has not been preserved

    Retirement home

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    The subject of this diploma thesis is the preparation of project documentation for the construction of a retirement home. The new building is located in Vysoké Mýto. The building is divided into three parts SO 01, SO 02 and SO 03. Part SO 01 has three floors and is partially basement. In the basement there are technical facilities, warehouses and a workshop. On the first floor there are offices and staff facilities, hygiene facilities, a dining room with its own kitchen for providing food for the entire building. There is also a surgery and a hairdresser/pedicure, which are also accessible to the public through a side entrance. On the second and third floors there are single rooms for clients, nurses' rooms with facilities, handy storage rooms for medicines, dirty and clean linen and other necessary materials. There are also social, reminiscence, rehabilitation, cleaning and housekeeping rooms. There are 8 single rooms on each floor. Part SO 02 has two above-ground floors and one underground floor. In the basement there is a technical room, an air conditioning machine room, a laundry room and a drying room with clean and dirty linen storage rooms, and a backup power source. The above-ground floor of this part serves mainly as a residential area, with a total of 11 double rooms designed here. Necessary facilities for staff, storage rooms, a café, a buffet, and others. The last southern part of SO 03 has only one above-ground floor. 7 double rooms, a nurse's room, storage rooms, a reminiscence room, and technical facilities are designed here. The detailed documentation for the diploma thesis is prepared only for part SO 01. The vertical load-bearing structures are made of ceramic blocks of the type and of lost formwork. The building is insulated with a contact insulation system. The horizontal ceiling structures and staircases are made of reinforced concrete. The building is covered with a flat vegetation roof

    Highway bridge at urban area

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    The aim of this work was to design a new bridge structure with 5 spans. 3 studies were prepared, from which I selected one, namely a monolithic two-girder variant made of prestressed concrete, which will replace the existing bridge structure consisting of prefabricated beams. The length of the bridge in the axis of the highway is 178m and the total width of the bridge is 25.9m. The work includes a static calculation, drawings of reinforcement, construction phases and bridge layout

    Construction technology project for the construction of a fire station in Rosice

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    The thesis focuses on the development of a construction and technological project for the construction of a new fire station in Rosice. The project includes the preparation and realization of the building, consisting of a garage section, technical facilities, and a two-story residential area for the fire rescue unit. The work includes the design of the construction site facilities, a time and financial plan, a technological procedure for the implementation of the monolithic ceiling, and a quality control and inspection plan. Furthermore, environmental and safety aspects of the construction are analyzed, including a proposal for LEED certification and a noise study. The project outcomes are supported by technical and economic analyses, emphasizing the optimization of construction processes

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