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    Artificial Intelligence techniques for searching paths and cycles in hypercubes

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    In this thesis we study Hamilton paths and cycles in hypercubes. We prove that any matching spanning at most five directions in an n-dimensional hypercube can be extended to a Hamilton cycle, and characterize when such matchings extend to Hamilton paths between specified vertices of opposite parity. Our proofs combine theoretical frameworks with computer-assisted verification using SAT solvers and the MathCheck methodology to establish base cases for n = 5. Furthemore, we explore Hamilton paths in hypercubes with specific properties and compare various SAT encodings for finding such paths

    The standing of principles of law in the legal philosophy of H. L. A. Hart, Ronald Dworkin and Gustav Radbruch

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    In my bachelor's thesis, I will focus on legal principles and their role in the philosophy of law, specifically within the frameworks of legal positivism, legal interpretivism, and non- positivismu. Each of these approaches will be presented through the lens of a prominent author. For legal positivism, I will examine H. L. A. Hart and his book The Concept of Law. For legal interpretivism, I will analyze Ronald Dworkin and his book Law's Empire. For non-positivism I will consider Gustav Radbruch and his famous formula first unveiled in his essay Statutory Lawlessness and Supra-Statutory Law. I will analyze how these theories conceptualize and utilize legal principles, exploring the functions these principles serve within each framework. Specifically, I will investigate whether legal principles play a significant role in the system as a whole or whether they recede into the background. Subsequently, I will compare the advantages and disadvantages of these various approaches and contrast them with my own understanding of legal principles

    Neural signalling pathways regulation at protein level

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    Neurodegenerative diseases are incurable disorders associated with the loss of cells in the central nervous system. The neural cell loss severely affects brain functions which ultimately results in a patient's death. Cell-based therapy using neural stem cells represents a promising strategy. These neural stem cells are expected to stimulate the regeneration of damaged tissue either by protein secretion or through the direct replacement by cells that differentiate into neurons or glial cells upon transplantation. However, current protocols for neural stem cell differentiation yield heterogeneous cell populations so a better understanding of regulatory mechanisms is required. It is crucial to determine the proliferation and differentiation potential to fully characterise the cells intended for transplantation. One of the key factors driving the efficacy of cell therapy is the timing of its administration to the patient. Thus, a search for suitable biomarkers that would assess the development of the disease is essential not only for the precise timing of transplantation but also for monitoring cell therapy outcomes. This dissertation thesis provides a detailed study of human neural stem cells during in vitro differentiation, aiming to uncover the pathways that regulate this process. The first part of..

    Expressionist Theatre and Denis Johnston's The Old Lady Says 'No!'

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    This thesis presents a comparative reading of Denis Johnston's The Old Lady Says 'No!' alongside nine expressionist plays that he was exposed to leading up to The Old Lady Says 'No!''s 1929 premiere, in order to uncover the intersections of motifs and techniques among them. The plays include both George S. Kaufman and Marc Connelly's Beggar on Horseback and Josef Čapek's The Land of Many Names as well as works by Luigi Pirandello, August Strindberg, Ernst Toller, Eugene O'Neill, Georg Kaiser, and Elmer Rice. The aim of this thesis is to assess the The Old Lady holds a place among the tapestry of works that constitute the expressionist genre, and to reconcile the fact that individual theatrical techniques and characteristics ascribed to expressionism can also be found in other genres. The introduction consists of a plot summary of The Old Lady, a general overview of the topics covered and a structural layout of the study. The first chapter introduces expressionist theatre as a genre. The following chapter contains an overview of the development of the Dublin theatre scene and Johnston's involvement in the Dublin Drama League and later the Gate Theatre. Chapter three introduces The Old Lady Says 'No!' itself, the play's production history, as well as its structure and theatrical elements. The fourth..

    Professional support for healthcare professionals in the field of perinatal loss: experiences with the implementation of a new service in a Czech hospital environment

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    Perinatal death is a long-term underestimated life situation that brings serious psychological, social and economic consequences for the affected family and society. The attitudes and behaviour of healthcare professionals have an important influence on the parents' decision-making and on their overall ability to get through this extremely difficult situation as best as possible. Empathetic and supportive care contributes to positive memories of parents about their child, while discord between parents and healthcare professionals can have a long-term negative impact on their future life, including mental health. Improving the quality of care in a situation of perinatal loss requires the development of various forms of professional support so that healthcare professionals can acquire knowledge in palliative care, develop their psychosocial skills and have the opportunity to use support to process the burden resulting from the stress they experience. The aim of the work is to use the current knowledge in the field of perinatal loss from the perspective of healthcare professionals and affected families and, with support in the humanistic person-centered approach of Carl Rogers, to describe the experiences of healthcare professionals from the neonatal department with the implementation of professional..

    The role of Christian belief in psychodynamic therapy

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    The presented diploma thesis deals with psychodynamic psychotherapy in the Christian faith with a focus on the most important aspects of the client-therapist relationship. The main sources of knowledge on which it is based are the author's long-term practice as a therapist, an initiate, together with the use of literature from our and foreign origins. In the introduction, without ambitions for completeness, she presents the findings of theorists and fellow therapists touching on the relationship between faith/religiosity and psychotherapy. She primarily notes the role of different life attitudes of Christians and the majority population and their manifestations in situations such as ending one's own life by one's own decision, sexuality, masturbation, etc. The thesis deals in more depth with the description of specific modalities of therapeutic work with a client of the Christian faith, where it again analyzes its pros, cons and differences in relation to psychotherapy in general. The key here is the idea of God and the client's relationship to Him resulting from it and what influences it. A specific type of client of the Christian faith is the initiated person, to whom an entire chapter is dedicated. This provides an insight into what personality problems this clientele living a specific way of..

    Book culture in the hussite works of Zdeněk Nejedlý

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    Annotation: The aim of this bachelor thesis is to determine if Zdeněk Nejedlý perceives sources in his works The Beginnings of Hussite chant and History of Hussite chant as a part of the book culture. The first chapter summarizes Nejedlý's life and work. Nejedlý's approach to the topic of Hussites and the scientific methods used by him are described in the following chapters. The thesis also focuses on contemporary and current reflection of Nejedlý's work. The final chapters analyze Nejedlý's hussite work more closely with an emphasis on Nejedlý's work with the historical manuscripts as a part of the book culture. Keywords: Zdeněk Nejedlý, Hussites, book culture, manuscript

    Self-defence in Criminal Law

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    Self-defence in Criminal Law Abstract This thesis examines the legal institute of self-defence in criminal law, focusing on its theoretical foundations and practical problems, with special attention paid to the understudied concept of premature (self) defence. Combining an analysis of historical development, theoretical evaluation and legislative critique, it provides a comprehensive overview of self- defence as a circumstance excluding liability. The work traces the historical development of necessary defence in Czech law, emphasising its roots in natural law and its codification in response to social needs. Key elements such as the direct threat of attack, the attack itself and its definition, the interests protected by the criminal law, and the not entirely obvious disproportionality are examined, along with variations in the form of excesses, premature (self) defence and its assessment, depending on the circumstances, as either a putative self-defence or a circumstance excluding liability sui generis as a performance of a duty. The thesis advocates that premature defence should be qualified in cases fulfilling the performance of the obligation laid down in Section 367 of the Criminal Code as a separate legal construct, not as an excess. In cases not fulfilling the above mentioned, it is important to..

    Social work with soldiers, war veterans, and their families.

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    (in English): This bachelor thesis focuses on the issue of social work with soldiers, war veterans and their families. The aim of this research probe is to analyze the specifics of the social services field, especially in the context of soldiers' return to civilian life, dealing with trauma associated with war experiences, and supporting families facing challenges associated with the military environment. The role of social workers in providing support to families of soldiers and war veterans is also described within the framework of the bachelor thesis. We identify specific challenges faced by families and analyze social work strategies to strengthen family relationships and ensure overall well-being. Overall, the main aim of this thesis is to contribute to a better understanding and improvement of social work in this specific area of the military environment, with an emphasis on supporting soldiers, veterans and their families in overcoming the challenges associated with military service and subsequent return to civilian life

    Legal Binomials in Old Bailey Corpus

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    Thesis abstract Binomials are expressions occurring in almost every legal text. Although they stand for markers of such texts, there is no definition of what features should legal binomials have. A number of works subsume within the concept of binomial any combination of two words such as 'ladies and gentlemen' or 'four by four' but legal binomials tends to be fixed as their meaning needs to be precise and unmistakable. It is therefore important to emphasize the features of legal binomials that separate them even from other types of binomials. This work seeks to answer this question by probing into the Old Bailey Corpus and searching for adjectival binomials that evince affiliation to the legal language. The corpus contains both spoken and written language of the proceedings with the speakers and scribes of various social background and therefore offers an opportunity to explore the breadth of the use of binomials in legal environment. The Old Bailey Corpus also keeps records of who used the binomial, in which procedural part of the proceedings and what was the overall result of the proceedings. There is no ambition to connect each binomial with ever trial it occurred in but to gain a general idea of what is the intended use of the expressions in the legal environment. Key words: Binomials, Old Bailey..

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