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Chair-based yoga programme for older adults with multimorbidity: RCT with embedded economic and process evaluations
Get PDFChurch of England ministry in the south-west peninsular: Gaps and priorities
Get PDFAs part of a review of ministry and training for ministry by the dioceses of Exeter and Truro in 2023, an online survey was distributed to clergy and lay ministers. The paper reports on how 92 parochial incumbents (or incumbent status clergy), 80 assistant clergy (self-supporting ministers and curates), and 94 Readers rated the importance of various tasks in their ministries, how well they felt they were equipped to do those tasks, and what they felt should be the priorities for ministry and training in their dioceses. In general, traditional tasks of preaching and teaching, leading worship, and pastoral care were rated as most important, while those rated as least important were management and administration, talking about giving and raising money, and speaking up on local issues. When it came to the gap between importance and being equipped, supporting personal wellbeing was rated as most under-equipped by incumbents, equipping disciples by assistant clergy, and bringing others to faith by Readers. The top ministry priorities were equipping lay ministries, team working, and supporting evangelists, while the lowest priorities were remaining faithful to received traditions, maintaining the parish system, and developing digital ministries. Participants recognised the need to select the right people to do particular ministries and support the mental health and wellbeing of ministers
International consensus is needed on a core outcome set to advance the evidence of best practice in cancer prehabilitation services and research
Get PDFPrehabilitation aims to optimise patients' physical and psychological status before treatment. The types of outcomes measured to assess the impact of prehabilitation interventions vary across clinical research and service evaluation, limiting the ability to compare between studies and services and to pool data. An international workshop involving academic and clinical experts in cancer prehabilitation was convened in May 2022 at Sheffield Hallam University's Advanced Wellbeing Research Centre, England. The workshop substantiated calls for a core outcome set to advance knowledge and understanding of best practice in cancer prehabilitation and to develop national and international databases to assess outcomes at a population level
Building resilient leadership: A study exploring leadership development during uncertainty
Get PDFEffective small and medium enterprise (SME) leadership demands creative solutions, to ensure organisations survive, and thrive, during the turbulent times that COVID-19 continues to bring. This paper explores how SME leaders (in micro and small organisations) prioritise and access the skills and development needed to provide effective and sustainable leadership to organisations, focusing on the role of resilience and the benefits it provides. Participants were selected through purposive and snowballing sampling. Online surveys and semi-structured interviews were conducted and provide qualitative data that contributes to an understanding of the role of resilience and the view of participants as to what is needed to effectively respond to a dynamic environment. Evidence shows that SME leaders prioritise learning and development opportunities that provide demonstrable benefits throughout the organisation. Building business resilience remains a fuzzy concept, however, viewing resilience as a multi-level construct offers benefits when designing and delivering development opportunities. It is found that networking, partnerships, and relationship building promote resilience and may offer a solution to how to embed resilience building into development opportunities that SME leaders value and wish to engage with. This article contributes by illustrating and exploring leadership development within SMEs during a period of unexpected and untested uncertainty. The pandemic caused major shock waves within business communities and SMEs were significantly affected. The research is limited in that it is (expected) to be a once in a lifetime event and as such conditions may not be replicable, however learning opportunities for other ‘shock’ events are possible. The findings of this paper have relevance to practice, in that while the event may be a one-off, shocks to the business environment are not
Picture Perfect: Perfectionistic Self-Presentation, Instagram Intrusion, and Body Satisfaction in Young Women
Get PDFPerfectionistic self-presentation (the desire to appear perfect to others) is related to decreased body satisfaction and intrusive (e.g., addictive or problematic) social media use in young women. Instagram, a highly visual social media platform, may serve as a medium for heightened body image concerns among this population. Exploring perfectionistic self-presentation on Instagram, by examining the extent to which women promote a perfect image on Instagram (perfectionistic self-promotion) and avoid presenting an imperfect image on Instagram (non-display of imperfection and non-disclosure of imperfection), may help to further understand its role in these issues. To test this idea, we recruited two non-clinical samples of young women (Sample 1: cross-sectional, N = 392; Sample 2: two-wave longitudinal, N = 176) to examine the relationships between perfectionistic self-presentation on Instagram, Instagram intrusion and body satisfaction. Findings revealed that dimensions of perfectionistic self-presentation on Instagram were negatively associated with body satisfaction, both cross-sectionally and over time and positively associated with Instagram intrusion, cross-sectionally. Non-display of imperfection appeared to be the most important dimension. Overall, our findings offer initial support for examining perfectionistic self-presentation on Instagram, and its utility in understanding the body satisfaction of young women
The Efficacy of a Novel Biological Formulation from Bovine Milk Colostrum Exosomes and its Growth Factors in Enhancing the Process of Wound Healing
Get PDFThe management of wounds is a significant issue that impacts individuals, healthcare systems, and society at large. This study evaluated a novel formulation extracted from Bovine Colostrum with a unique combination of 20 different growth factors and exosomes, known for its exceptional properties in promoting cell proliferation and regeneration. The newly developed combination of different biological components was referred to as Rigemed D (RD). This study aims to determine the effects of different doses of RD on cell survival (using CCK8) and to assess its antioxidant effect using the Comet assay in the presence of hydrogen peroxide (H2O2) on two human cell types, fibroblasts and immortalised keratinocytes (HaCaT cell line). The study results revealed that RD, at doses of 1, 1.5 and 2% v/v, significantly improved cell viability four, six and 12 times, respectively, compared to the control group (p<0.00001). Furthermore, the Comet assay showed a two-fold reduction in DNA damage in RD-treated cells at 2% v/v without and with H2O2 (p<0.001). The effect of RD on cell proliferation and migration was evaluated using a scratch assay on fibroblasts and HaCaT cells. The findings demonstrated a four-fold increase in cell proliferation and migration at 1 and 24 hours (p<0.001). Immunohistochemistry confirmed this claim (p<0.001). Also, angiogenesis induction of RD was assessed on Human Vein Umbilical Endothelial Cells (HUVEC), showing that RD significantly enhanced the proliferation of endothelial HUVEC cells (p<0.0001). In conclusion, RD is a promising vitalising compound with exceptional capabilities in promoting cell proliferation, migration, and regeneration. It also shows a significant antioxidant effect and has the potential to support all phases of wound healing involving cell proliferation, re-epithelialisation, angiogenesis, and tissue maturation. Hence, the present formulation presents a promising foundation for developing a 3D bio-printed membrane, potentially expediting the wound healing process
Anti-racist and decolonial practice in teacher education
Get PDFPostgraduate Certificate of Education (PGCE) mathematics students work in groups to create lesson plans and resources about the historical and cross-cultural roots of mathematics, with written reflections on celebrating diversity. Last years’ lesson activities included: ‘The Game AYO’, ‘Yoruba Number System’, ‘Towers of Hanoi’, ‘Crop Circles’ and ‘Tangrams, Sudoku and Kenken’. The students reflected on the implications on their classroom teaching with pupils, relating to unconscious bias and decolonisation of the national curriculum. At the summer British Society for Research into Learning Mathematics (BSRLM) workshop 2021, ideas were shared from university colleagues and students at York St. John University and for classroom teaching. BSRLM colleagues contributed to the Padlet for initial teacher education. Collaborative curriculum development practice takes place with student teachers, involving lesson planning of activities for classroom practice in placement schools. Reflections about critical mathematics education is outlined with feedback from pupils. Learning about contributions to mathematics from people from around the world can help pupil engagement and interest, whilst addressing diversity, inclusion and social justice issues.
Keywords: anti-racism; decolonial practice, critical mathematics education, social justic
P161 The use of Novel Natural Treatments for Inflammatory Bowel Diseases
Get PDFBackground Background: Free radicals and reduced antioxidant levels lead to oxidative stress, which plays a role in causing Inflammatory Bowel Disease (IBD). IBD is a chronic gastrointestinal autoimmune condition that involves an abnormal immune response. This includes Crohn's disease (CD) and ulcerative colitis (UC). In the previous studies, we demonstrated the antioxidant effect of Inonotus obliquus (IO) and flavonoids such as quercetin and epicatechin on lymphocytes from IBD patients. In vitro studies have shown that Chaga extract is effective in reducing oxidative stress in lymphocytes of both healthy individuals and those with IBD. This suggests that Chaga extract may be a useful supplement for anyone looking to inhibit oxidative stress. Methods Methods: In our current study, Cord Blood Stem Cells -derived Exosomes (CBSC Exo) and their synthesised miRNAs were investigated as antioxidant/anti-inflammatory elements on lymphocytes and 3D intestinal epithelial model. There were seven miRNAs found in CBSCs Exo, and among them were two miRNAs that were identified as novel. The Peripheral Blood Monocyte Cells (PBMCs) from IBD patients and healthy individuals after challenging with H2O2 or Interleukin 6 were treated with CBSCs Exo, transfected with miRNA novels or both. The treatment method also was applied to the EpiltestinalTK 3D model from Mattek. Various techniques were utilised, including the Comet assay, Fast Microplate DNA damage assay, and CCK8. Results The findings of the study indicate that the administration of CBSC-derived Exo, Let-7c-mimic miRNA, Let7bSb miRNA, as well as Novel 1 and Novel 2 miRNAs on the 3D model intestine, significantly decreased the level of DNA damage when compared to the positive control H2O2 and IL6, as well as the untreated samples. Conclusion Conclusions: In conclusion, certain natural substances like flavonoids, Inonotus obliquus, and exosomes derived from CBSCs may have an advantage in decreasing significantly oxidative stress and DNA damage in IBD Peripheral Blood Mononuclear Cells (PBMCs) and inflamed intestinal 3D models
Navigating through Transnational Experiences of Chinese Working Holiday Makers in New Zealand
Get PDF‘My sexual desires, everything, my normal life just stops’; A qualitative study of male sexual health in Inflammatory Bowel Disease
Get PDFAim: To describe and interpret the sexual health experiences of men with IBD.
Design: Interpretive qualitative study.
Methods: In-depth, semi-structured interviews were conducted with 22 men with a diagnosis of Inflammatory Bowel Disease. Interviews were digitally audio-recorded and transcribed verbatim. Data were analysed using constant comparative, thematic analysis.
Results: Three themes were identified from interview data: (1) the disease shapes intimate connections, (2) the disease thwarts sexual experiences, (3) the disease disrupts male gender norms. Men reported that active disease lowered libido and could change pre-, inter- and post-coital sexual practices. All participants noted that health professionals did not initiate discussion of sexual health and well-being needs in the outpatient hospital setting. Men who engaged in receptive anal sex reported a lack of disease-specific guidance and understanding from professionals.
Conclusion: Inflammatory bowel disease can negatively impact the sexual well-being, gender identity and activities of men. Further research is required to identify the care preferences of men with IBD and clarify the barriers and facilitators to sexual health assessment so that nurses may better support the health needs of this population.
Implications for the profession and patient care: This study highlights the need for sexual health and well-being support that is specific to disease and gender in IBD. There is a paucity of information and guidance for men with peri-anal disease and proctitis who engage in receptive anal sex, which requires urgent attention