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Biblioteca, 2024/2025
No full textEl folleto anual de la Biblioteca 2024-2025 contiene información general sobre las bibliotecas de la Universidad de Navarra, los servicios que presta y algunos datos estadísticos correspondientes al año anterior
Satisfacción de los pacientes con los cuidados enfermeros en una Unidad de Cuidados Intensivos medida a través de la escala Nursing Intensive-Care Satisfaction-Scale (NICSS)
No full textIntroducción: La satisfacción del paciente con los cuidados enfermeros se ha convertido en un
determinante clave de la calidad de la atención hospitalaria.
Objetivos: Evaluar la satisfacción con los cuidados enfermeros en el contexto del paciente
crítico; determinar su correlación con las variables sociodemográficas y clínicas y describir las
percepciones del paciente sobre aspectos relacionados con el cuidado enfermero.
Metodología: Estudio descriptivo, prospectivo, correlacional en la Unidad de Cuidados Intensivos (UCI) de un hospital universitario de nivel terciario. Se evaluó el nivel de satisfacción a
todos los pacientes dados de alta de la UCI. Se utilizó la escala validada en castellano Nursing Intensive-Care Satisfaction-Scale (NICSS). Además, se recogieron datos sociodemográficos
y clínicos y se realizaron tres preguntas abiertas. Se utilizó estadística descriptiva e inferencial
considerándose estadísticamente significativos p < 0,05. Las preguntas abiertas se examinaron
mediante un análisis de contenido del lenguaje. Se obtuvo la aprobación del Comité de Ética
del hospital.
Resultados: Aceptaron participar 111 pacientes, con una media de edad de 64,18 años (IC 95%
61,36-66,88) y un nivel de satisfacción medio de 5,83 (IC 95% 5,78-5,88) de una puntuación
máxima de seis. Las mujeres, los pacientes de mayor edad y los que reflejan mayor grado de
recuperación, son los que refieren mayor satisfacción. Del análisis de las preguntas abiertas
de las encuestas surgieron tres temas principales: relación enfermera paciente, entorno de la
práctica profesional y naturaleza de la UCI. Conclusión: El nivel de satisfacción de los pacientes con los cuidados enfermeros fue elevado. La
edad, el sexo y el grado de recuperación influyeron de manera significativa en su percepción. La
relación enfermera-paciente y el entorno de la práctica profesional fueron aspectos destacados
por los pacientes. El modelo de la práctica profesional incorporado en la institución puede
favorecer estos resultados
Cubiertas verdes en edificios educativos. Viabilidad de rehabilitación y renaturalización
No full textCon el crecimiento continuo de las ciudades, el entorno construido ha invadido el
espacio natural, acentuando los efectos del cambio climático. La contaminación,
las altas temperaturas y la escasez de espacios verdes afectan la salud y el bienestar
de las personas, especialmente de los más vulnerables, como los niños.
Ante esta preocupación, el objetivo de esta investigación fue profundizar en la
intersección entre la arquitectura y la sostenibilidad, abordando la rehabilitación
y renaturalización de edificios existentes a través de cubiertas verdes.
La investigación se centra en uno de los pilares fundamentales de la estructura
de nuestra sociedad: los colegios, tomando como caso de estudio el CPEIP García
Galdeano de Pamplona. Se exploró la viabilidad de rehabilitar sus cubiertas,
transformándolas en ajardinadas mediante un análisis exhaustivo del estado
actual del edificio, encuestas y participación de la comunidad educativa.
El objetivo último fue desarrollar una metodología que facilitase la toma de
decisiones en proyectos de rehabilitación a través de cubiertas ajardinadas
en colegios existentes. Con este propósito, se proponen dos herramientas: la
Herramienta de Viabilidad y Oportunidad, y la Herramienta para Propuestas.
Ambas se aplicaron al caso de estudio, evaluando la posibilidad de renaturalizar
sus cubiertas y estudiando la adecuación de tres diseños adecuados a diferentes
grados de presupuesto.
Los resultados obtenidos tras su análisis y comparación con otros colegios
de Pamplona, demuestran que estas soluciones son técnicamente viables y
profundamente beneficiosas para los niños, aunque los costos de construcción
y mantenimiento son significativos y pueden influir considerablemente en la
viabilidad de proyectos similares.With the continuous growth of cities, the built environment has encroached
upon natural spaces, accentuating the effects of climate change. Pollution, high
temperatures, and the scarcity of green spaces affect people’s health and well-being,
especially the most vulnerable, such as children.
In light of this concern, the objective of this research was to delve into the intersection
between architecture and sustainability, addressing the rehabilitation and re-
naturalization of existing buildings through green roofs.
The research focuses on one of the fundamental pillars of our society’s structure:
schools, using the CPEIP García Galdeano in Pamplona as a case study. The feasibility
of rehabilitating its roofs, transforming them into green spaces, was explored through
a comprehensive analysis of the building’s current state, surveys, and participation
from the educational community.
The ultimate goal was to develop a methodology that facilitates decision-making
in rehabilitation projects through green roofs in existing schools. To this end, two
tools are proposed: the Feasibility and Opportunity Tool, and the Proposal Tool. Both
were applied to the case study, evaluating the possibility of re-naturalizing its roofs
and studying the suitability of three designs tailored to different budget levels.
The results obtained after analysis and comparison with other schools in Pamplona
demonstrate that these solutions are technically viable and highly beneficial for
children, although the construction and maintenance costs are significant and can
considerably influence the feasibility of similar projects
Displays of anger in Turkish political discourse: a hard choice between cultural norms and political performance of anger
No full textThis paper examines the influence of cultural display rules on how high-status individuals,
such as political leaders, publicly express anger. Specifically, it focuses on Recep Tayyip
Erdoğan, who has been the Turkish leader since 2003. The study aims to understand the
extent to which Erdoğan’s expression of anger is influenced by cultural display rules, the
religious context stemming from his conservative electoral support, and his position as a
long-term populist political leader. Using extended conceptual metaphor theory (ECMT)
supported by corpus-assisted discourse analysis, the paper seeks to identify the contextual
factors that shape anger expressions (both direct and metaphorical) in the political discourse
of a populist leader in a collectivist culture. By comparing the conceptualization of ascribed
anger and inscribed anger expressions, the analysis reveals that Erdoğan’s discourse presents
two distinct scenarios for expressing anger toward ‘us’ and ‘others’. Additionally, it demonstrates how anger is strategically employed in culture-specific ways to navigate the
challenges posed by conflicting contextual factors
Exploring current and emerging therapies for porphyrias
No full textPorphyrias are rare, mostly inherited disorders resulting from altered activity of specific enzymes in the haem synthesis pathway that lead to accumulation of pathway
intermediates. Photocutaneous symptoms occur when excess amounts of photoreactive porphyrins circulate in the blood to the skin, whereas increases in potentially neurotoxic porphyrin precursors are associated with neurovisceral symptoms.
Current therapies are suboptimal and their mechanisms are not well established.
As described here, emerging therapies address underlying disease mechanisms by
introducing a gene, RNA or other specific molecule with the potential to cure or
slow progression of the disease. Recent progress in nanotechnology and nanoscience, particularly regarding particle design and formulation, is expanding disease
targets. More secure and efficient drug delivery systems have extended our toolbox
for transferring specific molecules, especially into hepatocytes, and led to proof-of-concept studies in animal models. Repurposing existing drugs as molecular chaperones or haem synthesis inhibitors is also promising. This review summarizes key
examples of these emerging therapeutic approaches and their application for hepatic
and erythropoietic porphyrias
The political economy of inequality, mobility and redistribution
No full textHow does the interaction between inequality and social mobility affect the choice of fiscal policy? I analyze this question in a model of democratic politics with imperfect tax enforcement, where the ability of individuals to evade taxes limits the amount of redistribution in the economy. Social mobility creates an insurance motive that increases voluntary compliance, favoring the tax enforcement process. In such an environment, redistributive pressures brought about by an increase in inequality are only implementable in highly mobile societies. On the contrary, when mobility is low, higher inequality reduces tax rates and does not translate into higher redistribution. Descriptive evidence based on a sample of 71 countries for the period 1980–2015 shows correlations among inequality, mobility and redistribution in line with the predictions of the model
AIDIP methodology for integrating standardization into collaborative research projects – Focus on smart and resilient cities
No full textThe European Commission fosters the integration of standardization in its Framework Programs since
a decade to disseminate and exploit the project results, thus increasing the projects’ impacts to
transfer research results into practice. Especially complex topics such as city resilience need urgently
research results to face the increasing hazards they are facing. However, there is a lack of a common
approach for integrating standardization in collaborative research projects. Furthermore, these
projects have the difficulty to engage the relevant stakeholders properly and to foster the application
of the resulting standards. This research addresses these issues by proposing the AIDIP methodology,
which includes the Analysis of standardization landscape, the Identification of end-user needs and
standardization potentials, the Definition of a standardization strategy, the Initiation of
standardization activities, and the Promotion and exploitation of conducted standardization work. In
addition, the research showed that standardization supports the engagement of project stakeholders
and that gathered factors to support the application of standards at city level are appropriate
Development of an in vitro platform for the analysis of contractile and calcium dynamics in single human myotubes
No full textIn vitro myotube cultures are widely used as models for studying muscle pathophysiology, but their limited maturation and heterogeneity pose significant challenges for functional analyses. While they remain the gold standard for studying muscle function in vitro, myotube cultures do not fully recapitulate the complexity and native features of muscle fibers, which may compromise their ability to predict in vivo outcomes. To promote maturation and decrease heterogeneity, we have incorporated engineered structures into myotube cultures, based on a PDMS thin layer with micrometer-sized grooves (mu Grooves) placed over a glass substrate. Different sizes and shapes of mu Grooves were tested for their ability to promote alignment and fusion of myoblasts and enhance their differentiation into myotubes. A 24 hour electrical field stimulation protocol (4 V, 6 ms, 0.1 Hz) was used to further promote myotube maturation, after which several myotube features were assessed, including myotube alignment, width, fusion index, contractile function, and calcium handling. Our results indicate superior calcium and contractile performance in mu Grooved myotubes, particularly with the 100 mu m-width 700 mu m-long geometry (7 : 1). This platform generated homogeneous and isolated myotubes that reproduced native muscle features, such as excitation-contraction coupling and force-frequency responses. Overall, our 2D muscle platform enables robust high-content assays of calcium dynamics and contractile readouts with increased sensitivity and reproducibility compared to traditional myotube cultures, making it particularly suitable for screening therapeutic candidates for different muscle pathologies
Phylogenomic insights into brucellaceae: The Pseudochrobactrum algeriensis case
No full textThe genus Pseudochrobactrum encompasses free-living bacteria phylogenetically close to Ochrobactrum opportunistic pathogens and to Brucella, facultative intracellular parasites causing brucellosis, a worldwide-extended and grave zoonosis. Recently, Pseudochrobactrum strains were isolated from Brucella natural hosts on Brucella selective media, potentially causing diagnostic confusions. Strikingly, P. algeriensis was isolated from cattle lymph nodes, organs that are inimical to bacteria. Here, we analyse P. algeriensis potential virulence factors in comparison with Ochrobactrum and Brucella. Consistent with genomic analyses, Western-Blot analyses confirmed that P. algeriensis lacks the ability to synthesize the N-formylperosamine O-polysaccharide characteristic of the lipopolysaccharide (LPS) of smooth Brucella core species. However, unlike other Pseudochrobactrum but similar to some early diverging brucellae, P. algeriensis carries genes potentially synthetizing a rhamnose-based O-polysaccharide LPS. Lipid A analysis by MALDI-TOF demonstrated that P. algeriensis LPS bears a lipid A with a reduced pathogen-associated molecular pattern, a trait shared with Ochrobactrum and Brucella that is essential to generate a highly stable outer membrane and to delay immune activation. Also, although not able to multiply intracellularly in macrophages, the analysis of P. algeriensis cell lipid envelope revealed the presence of large amounts of cationic aminolipids, which may account for the extremely high resistance of P. algeriensis to bactericidal peptides and could favor colonization of mucosae and transient survival in Brucella hosts. However, two traits critical in Brucella pathogenicity are either significantly different (T4SS [VirB]) or absent (erythritol catabolic pathway) in P. algeriensis. This work shows that, while diverging in other characteristics, lipidic envelope features relevant in Brucella pathogenicity are conserved in Brucellaceae. The constant presence of these features strongly suggests that reinforcement of the envelope integrity as an adaptive advantage in soil was maintained in Brucella because of the similarity of some environmental challenges, such as the action of cationic peptide antibiotics and host defense peptides. This information adds knowledge about the evolution of Brucellaceae, and also underlines the taxonomical differences of the three genera compared
Universidades privadas de Valencia: ¿discriminadas? Relaciones institucionales en crisis
No full textEl 2 de octubre de 2018, el tribunal superior de justicia de Valencia falló a favor de la Universidad
Cardenal Herrera CEU y la Universidad Católica de Valencia en su batalla contra la Generalitat
Valenciana. Los centros educativos habían recurrido las decisiones del gobierno autonómico,
que había incumplido los convenios de ambas instituciones con la Conselleria de Sanidad, que
garantizaban prácticas curriculares a sus alumnos del área de ciencias de la salud.
Dos años antes, en 2016, la Generalitat había decretado vetar las prácticas obligatorias de los
alumnos de las universidades privadas en los centros públicos. La nueva normativa suponía, de
facto, un golpe casi mortal para las universidades privadas, ya que el sistema privado de salud,
al que el gobierno pretendía derivar las prácticas de estos alumnos, no contaba con plazas suficientes para absorber a todos los alumnos.
En su sentencia, la sala de lo contencioso-administrativo del tribunal valenciano señalaba que,
en caso de revocar esos convenios, el derecho de esos alumnos a la educación “quedaría cercenado si se les impidiese realizar unas prácticas que son imprescindibles para obtener la titulación
que por sus estudios están cursando”, sobre todo teniendo en cuenta que las plazas para hacerlas en hospitales privados de la Comunidad Valenciana son insuficientes.
Las universidades privadas ganaron la primera batalla contra el gobierno del que dependían: la
Generalitat de Valencia.
Cuatro meses después, el 3 de julio de 2019, el tribunal constitucional español tumbó el veto
del gobierno autonómico valenciano a las prácticas de estudiantes de la privada en hospitales
públicos. ¿Hubo discriminación ideológica y religiosa, o se trató simplemente de un problema de masificación en las prácticas o de falta de coordinación? ¿Podría esa amenaza extenderse en el futuro
a universidades de otras partes de España